π Risk factors for primary middle east respiratory syndrome coronavirus illness in humans, Saudi Arabia, 2014
Β© 2016, Centers for Disease Control and Prevention (CDC). All rights reseved. Risk factors for primary Middle East respiratory syndrome coronavirus (MERS-CoV) illness in humans are incompletely understood. We identified all primary MERS-CoV cases reported in Saudi Arabia during MarchβNovember 2014 by excluding those with history of exposure to other cases of MERS-CoV or acute respiratory illness of unknown cause or exposure to healthcare settings within 14 days before illness onset. Using a caseβcontrol design, we assessed differences in underlying medical conditions and environmental exposures among primary case-patients and 2β4 controls matched by age, sex, and neighborhood. Using multivariable analysis, we found that direct exposure to dromedary camels during the 2 weeks before illness onset, as well as diabetes mellitus, heart disease, and smoking, were each independently associated with MERS-CoV illness. Further investigation is needed to better understand animal-to-human transmission of MERS-CoV.
keywords
π syndrome coronavirus (1074)
π dromedary camels (70)
π diabetes mellitus (16)
π respiratory syndrome (2004)
π acute respiratory (1734)
author
π€ Alraddadi, Basem M.
π€ Watson, John T.
π€ Almarashi, Abdulatif
π€ Abedi, Glen R.
π€ Turkistani, Amal
π€ Sadran, Musallam
π€ Housa, Abeer
π€ Almazroa, Mohammad A.
π€ Alraihan, Naif
π€ Banjar, Ayman
π€ Albalawi, Eman
π€ Alhindi, Hanan
π€ Choudhry, Abdul Jamil
π€ Meiman, Jonathan G.
π€ Paczkowski, Magdalena
π€ Curns, Aaron
π€ Mounts, Anthony
π€ Feikin, Daniel R.
π€ Marano, Nina
π€ Swerdlow, David L.
π€ Gerber, Susan I.
π€ Hajjeh, Rana
π€ Madani, Tariq A.
year
β° 2016
issn
π 10806059 10806040
volume
22
number
1
page
49-55
citedbycount
83
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