๐ Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan
We investigated whether infection with a novel human coronavirus (HCoV), called "New Haven coronavirus" (HCoV-NH)-which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63-is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoV-NL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan. ยฉ 2005 by the Infectious Diseases Society of America.
keywords
๐ rectal swabs (30)
๐ nasopharyngeal aspirates (24)
๐ polymerase chain (300)
๐ human coronavirus (623)
๐ real-time reverse (87)
๐ throat swab (43)
๐ chain reaction (303)
๐ nasopharyngeal aspirate (38)
author
๐ค Chang, Luan Yin
๐ค Chiang, Bor Luen
๐ค Kao, Chuan Liang
๐ค Wu, Mei Hwan
๐ค Chen, Pei Jer
๐ค Berkhout, Ben
๐ค Yang, Hui Ching
๐ค Huang, Li Min
year
โฐ 2006
issn
๐ 00221899
volume
193
number
2
page
283-286
citedbycount
41
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