๐ Antigenic characterization of a turkey coronavirus identified in poult enteritis- and mortality syndrome-affected turkeys
A turkey coronavirus (TCV [NC95]) was characterized by antigenic comparison with other avian and mammalian coronaviruses using immunofluorescence (FA) and immunoperoxidase (IP)procedures. Based on FA and IP procedures, TCV (NC95) was determined to be antigenically indistinguishable from turkey enteric (bluecomb) coronavirus (TECV). In addition, TCV (NC95) and TECV were found to be closely related to infectious bronchitis virus (IBV); a one-way antigenic relationship was demonstrated. Polyclonal anti-bodies specific for TECV and IBV reacted strongly against TCV (NC95), as determined by FA procedures. Monoclonal antibodies (MAbs) specific for IBV matrix protein (MAb 919) reacted strongly against TCV (NC95) and TECV as determined by FA and IP procedures; an IBV peplomer protein-specific MAb (MAb 94) did not recognize the two viruses. These studies suggest an identification of TCV (NC95) as a strain of TECV, and provide evidence of a close antigenic relationship between these viruses and IBV.
keywords
๐ closely related (222)
๐ bronchitis virus (233)
๐ infectious bronchitis (235)
๐ turkey coronavirus (48)
year
โฐ 1997
journal
๐ Avian Diseases
issn
๐ 00052086
volume
41
number
3
page
583-590
citedbycount
66
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