📄 Pathogenicity of 2 porcine deltacoronavirus strains in gnotobiotic pigs

© 2015, Emerging Infectious Diseases. To verify whether porcine deltacoronavirus infection induces disease, we inoculated gnotobiotic pigs with 2 virus strains (OH-FD22 and OH-FD100) identified by 2 specific reverse transcription PCRs. At 21–120 h postinoculation, pigs exhibited severe diarrhea, vomiting, fecal shedding of virus, and severe atrophic enteritis. These findings confirm that these 2 strains are enteropathogenic in pigs.

keywords 🔗 reverse transcription (205) 🔗 coronavirus infection (270) 🔗 virus strain (138)

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