๐ Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility - King County, Washington, March 2020.
Older adults are susceptible to severe coronavirus disease 2019 (COVID-19) outcomes as a consequence of their age and, in some cases, underlying health conditions (1). A COVID-19 outbreak in a long-term care skilled nursing facility (SNF) in King County, Washington that was first identified on February 28, 2020, highlighted the potential for rapid spread among residents of these types of facilities (2). On March 1, a health care provider at a second long-term care skilled nursing facility (facility A) in King County, Washington, had a positive test result for SARS-CoV-2, the novel coronavirus that causes COVID-19, after working while symptomatic on February 26 and 28. By March 6, seven residents of this second facility were symptomatic and had positive test results for SARS-CoV-2. On March 13, CDC performed symptom assessments and SARS-CoV-2 testing for 76 (93%) of the 82 facility A residents to evaluate the utility of symptom screening for identification of COVID-19 in SNF residents. Residents were categorized as asymptomatic or symptomatic at the time of testing, based on the absence or presence of fever, cough, shortness of breath, or other symptoms on the day of testing or during the preceding 14 days. Among 23 (30%) residents with positive test results, 10 (43%) had symptoms on the date of testing, and 13 (57%) were asymptomatic. Seven days after testing, 10 of these 13 previously asymptomatic residents had developed symptoms and were recategorized as presymptomatic at the time of testing. The reverse transcription-polymerase chain reaction (RT-PCR) testing cycle threshold (Ct) values indicated large quantities of viral RNA in asymptomatic, presymptomatic, and symptomatic residents, suggesting the potential for transmission regardless of symptoms. Symptom-based screening in SNFs could fail to identify approximately half of residents with COVID-19. Long-term care facilities should take proactive steps to prevent introduction of SARS-CoV-2 (3). Once a confirmed case is identified in an SNF, all residents should be placed on isolation precautions if possible (3), with considerations for extended use or reuse of personal protective equipment (PPE) as needed (4).
keywords
๐ personal protective (55)
๐ transcription-polymerase chain (58)
๐ reverse transcription (205)
๐ polymerase chain (300)
๐ novel coronavirus (684)
๐ reverse transcription-polymerase (55)
๐ protective equipment (57)
๐ health care (123)
๐ chain reaction (303)
author
๐ค Kimball, Anne
๐ค Hatfield, Kelly M
๐ค Arons, Melissa
๐ค James, Allison
๐ค Taylor, Joanne
๐ค Spicer, Kevin
๐ค Bardossy, Ana C
๐ค Oakley, Lisa P
๐ค Tanwar, Sukarma
๐ค Chisty, Zeshan
๐ค Bell, Jeneita M
๐ค Methner, Mark
๐ค Harney, Josh
๐ค Jacobs, Jesica R
๐ค Carlson, Christina M
๐ค McLaughlin, Heather P
๐ค Stone, Nimalie
๐ค Clark, Shauna
๐ค Brostrom-Smith, Claire
๐ค Page, Libby C
๐ค Kay, Meagan
๐ค Lewis, James
๐ค Russell, Denny
๐ค Hiatt, Brian
๐ค Gant, Jessica
๐ค Duchin, Jeffrey S
๐ค Clark, Thomas A
๐ค Honein, Margaret A
๐ค Reddy, Sujan C
๐ค Jernigan, John A
year
โฐ 2020
journal
๐ MMWR Morb Mortal Wkly Rep
issn
๐
volume
number
page
citedbycount
0
download
๐ [BibTeX]