๐ Testing the repatriated for SARS-Cov2: Should laboratory-based quarantine replace traditional quarantine?
BACKGROUND: An ongoing epidemic of respiratory diseases caused by a novel coronavirus (COVID 2019, SARS-CoV2) started in Wuhan, Hubei, in China at the end of December 2019. The French government decided to repatriate the 337 French nationals living in Wuhan and place them in quarantine in their home country. We decided to test them all for SARS-Cov2 twice in order to reduce anxiety among the population and decision-makers. METHODS: We investigated the presence of SARS-CoV-19 in asymptomatic carriers by testing all repatriated patients within the first 24 h of their arrival in France and at day 5. Viral RNA was extracted from pooled nasal and oropharyngeal swab fluids or sputum in the absence of nasal/oropharyngeal swabs. Detection of SARS-CoV-2 RNA was then carried out using several real-time reverse transcription (RT)-PCR assays. RESULTS: We tested 337 passengers at day 0 and day 5. All the tests for SARS-CoV2 were negative. By optimising the sampling process, sending samples sequentially and reducing the time-scale for biological analysis, we were able to test the samples within 5 h (including sampling, shipment and biological tests). CONCLUSION: Optimising our procedures reduces anxiety and reassures the population and decision makers.
keywords
๐ Anxiety (36)
๐ COVID-19 (1240)
๐ Coronavirus (5664)
๐ Early (29)
๐ Quarantine (110)
๐ Rapid testing ()
๐ reverse transcription (205)
๐ novel coronavirus (684)
๐ real-time reverse (87)
author
๐ค Lagier, Jean Christophe
๐ค Colson, Philippe
๐ค Tissot Dupont, Herve
๐ค Salomon, Jerome
๐ค Doudier, Barbara
๐ค Aubry, Camille
๐ค Gouriet, Frederique
๐ค Baron, Sophie
๐ค Dudouet, Pierre
๐ค Flores, Remi
๐ค Ailhaud, Lucie
๐ค Gautret, Philippe
๐ค Parola, Philippe
๐ค La Scola, Bernard
๐ค Raoult, Didier
๐ค Brouqui, Philippe
year
โฐ 2020
journal
๐ Travel Med Infect Dis
issn
๐
volume
number
page
citedbycount
0
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