๐ Bats are natural reservoirs of SARS-like coronaviruses
Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-Co. Vs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-Co. Vs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group.
keywords
๐ closely related (222)
๐ etiological agent (62)
๐ respiratory syndrome (2004)
๐ acute respiratory (1734)
author
๐ค Li, Wendong
๐ค Shi, Zhengli
๐ค Yu, Meng
๐ค Ren, Wuze
๐ค Smith, Craig
๐ค Epstein, Jonathan H.
๐ค Wang, Hanzhong
๐ค Crameri, Gary
๐ค Hu, Zhihong
๐ค Zhang, Huajun
๐ค Zhang, Jianhong
๐ค McEachern, Jennifer
๐ค Field, Hume
๐ค Daszak, Peter
๐ค Eaton, Bryan T.
๐ค Zhang, Shuyi
๐ค Wang, Lin Fa
year
โฐ 2005
journal
๐ Science
issn
๐ 00368075 10959203
volume
310
number
5748
page
676-679
citedbycount
936
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