📄 Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV.

First reported from Wuhan, The People's Republic of China, on 31 December 2019, the ongoing outbreak of a novel coronavirus (2019-nCoV) causes great global concerns. Based on the advice of the International Health Regulations Emergency Committee and the fact that to date 24 other countries also reported cases, the WHO Director-General declared that the outbreak of 2019-nCoV constitutes a Public Health Emergency of International Concern on 30 January 2020. Together with the other two highly pathogenic coronaviruses, the severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), 2019-nCov and other yet to be identified coronaviruses pose a global threat to public health. In this mini-review, we provide a brief introduction to the pathology and pathogenesis of SARS-CoV and MERS-CoV and extrapolate this knowledge to the newly identified 2019-nCoV.

keywords 🔗 *coronavirus (5664) 🔗 *immnopathology () 🔗 *immune responses (142) 🔗 *pathogenesis (423) 🔗 *respiratory tract (344) 🔗 *virus classification (1) 🔗 severe acute (1373) 🔗 syndrome coronavirus (1074) 🔗 highly pathogenic (100) 🔗 public health (392) 🔗 novel coronavirus (684) 🔗 respiratory syndrome (2004) 🔗 acute respiratory (1734)

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