An indirect fluorescent antibody technique has been developed for use with coronaviruses 229E and OC43. For the former virus, WI-38 cells were used as the host system, and for the latter LLC-MK2 cells were employed. Human serum pairs which were known to show a rise in antibody titer by other serologic techniques were tested by the FA method. Comparison of results obtained by different procedures showed that FA was specific and would be a useful addition to available methods for identifying infection serologically.
keywords
year ⏰ 1977
issn 🗄 15353699 00379727
volume 155
number 2
page 143-148
citedbycount 8
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