📄 Fatal Gastroenteritis Associated With Coronaviruslike Particles

The role of human enteric coronaviruses in infantile gastroenteritis is controversial. We detected coronavirus-like particles in the intestinal contents and within the epithelial cells of the ileum in a 15-month-old infant who had postmortem evidence of severe enteritis. Ultrastructural findings consistent with in vivo coronavirus replication in the human small intestine support a causative role for this agent in gastroenteritis. © 1985, American Medical Association.

keywords 🔗 enteric coronavirus (111) 🔗 virus replication (219) 🔗 epithelial cells (128) 🔗 small intestine (43)

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