The coronavirus E protein is a small membrane protein that has an important role in the assembly of virions. Recent studies have indicated that the E protein has functions during infection beyond assembly, including in virus egress and in the host stress response. Additionally, the E protein has ion channel activity, interacts with host proteins, and may have multiple membrane topologies. The goal of this review is to highlight the properties and functions of the E protein, and speculate on how they may be related. licensee MDPI, Basel, Switzerland.
year โฐ 2012
issn ๐Ÿ—„ 19994915
volume 4
number 3
page 363-382
citedbycount 30