📄 Receptor-Dependent Coronavirus Infection of Dendritic Cells

In several mammalian species, including humans, coronavirus infection can modulate the host immune response. We show a potential role of dendritic cells (DC) in murine coronavirus-induced immune modulation and pathogenesis by demonstrating that the JAW SII DC line and primary DC from BALB/c mice and p/p mice with reduced expression of the murine coronavirus receptor, murine CEACAM1a, are susceptible to murine coronavirus infection by a receptor-dependent pathway.

keywords 🔗 dendritic cells (45) 🔗 coronavirus infection (270) 🔗 immune response (314) 🔗 murine coronavirus (140)

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