📄 Potential targets for anti-SARS drugs in the structural proteins from SARS related coronavirus

This is a further study on the severe acute respiratory syndrome (SARS) using the probabilistic models. The purpose was to define the potential targets for anti-SARS drugs in the structural proteins from human SARS related coronavirus (SARS-CoV) while knowing little about the functional sites and possible mutations in these proteins. From a probabilistic viewpoint, we can theoretically select the amino acid pairs as potential candidates for anti-SARS drugs. These candidates have a greater chance of colliding with anti-SARS drugs, are more likely to link with the protein functions and are less vulnerable to mutations. © 2004 Elsevier Inc.

keywords 🔗 severe acute (1373) 🔗 amino acid (454) 🔗 structural proteins (197) 🔗 respiratory syndrome (2004) 🔗 acute respiratory (1734)

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