📄 Nucleocapsid phosphorylation and RNA helicase DDX1 recruitment enables coronavirus transition from discontinuous to continuous transcription

© 2014 Elsevier Inc. GSK-3 inhibitor reduces coronavirus nucleocapsid phosphorylation (pN) and titerpN recruits RNA helicase DDX1 and is crucial for long sgmRNA and gRNA synthesisDDX1 knockdown or loss of helicase activity impairs longer sgmRNAs synthesispN/DDX1 bind to viral genome and assist template readthrough of viral body TRSs

keywords 🔗 viral genome (96)

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