๐ Coronavirus associated with an enteric syndrome on a quail farm
An enteric syndrome was observed in quail (Coturnix coturnix) semi-intensively reared for restocking in Apulia (southern Italy). The birds showed depression, severe diarrhoea, dehydration and reduced growth. Mortality occurred particularly in young birds. At necropsy the prominent lesion was enteritis. A coronavirus was detected by electron microscopy and reverse transcriptase-polymerase chain reaction in the faeces and in the intestinal content of the dead quails. The virus could not be cultivated in chicken embryos. By sequence analyses of a fragment (409 nucleotides) of region 1b of the polymerase gene, the quail coronavirus displayed โค93% nucleotide identity to avian coronaviruses (group 3 coronaviruses) - whereas by analysis of the S1 portion of the spike protein-encoding gene, the quail coronavirus displayed 16% to 18% amino acid identity with infectious bronchitis virus, and 79% to 81% identity with turkey coronavirus. Altogether, the findings suggest the existence of a novel coronavirus genetically related to turkey coronavirus. ยฉ 2007 Houghton Trust Ltd.
keywords
๐ spike protein (353)
๐ bronchitis virus (233)
๐ amino acid (454)
๐ polymerase chain (300)
๐ novel coronavirus (684)
๐ reverse transcriptase (87)
๐ infectious bronchitis (235)
๐ turkey coronavirus (48)
๐ findings suggest (77)
๐ electron microscopy (149)
๐ chain reaction (303)
author
๐ค Circella, Elena
๐ค Camarda, Antonio
๐ค Martella, Vito
๐ค Bruni, Giordano
๐ค Lavazza, Antonio
๐ค Buonavoglia, Canio
year
โฐ 2007
journal
๐ Avian Pathology
issn
๐ 14653338 03079457
volume
36
number
3
page
251-258
citedbycount
28
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