📄 Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020.

The first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3-23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a single nucleotide substitution to the reference strain from Wuhan. Neutralising antibody response appeared within 9 days along with specific IgM and IgG response, targeting particularly nucleocapsid and spike proteins.

keywords 🔗 *COVID-19 (1240) 🔗 *SARS-CoV-2 (551) 🔗 *antibodies (608) 🔗 *coronavirus (5664) 🔗 *humoral immunity () 🔗 *immunofluorescence assay () 🔗 *microneutralisation test () 🔗 *western blotting (5) 🔗 *whole-genome sequencing () 🔗 spike protein (353) 🔗 virus strain (138)

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