๐ The molecular dynamics of feline coronaviruses
Feline coronaviruses are widespread and come in different flavors. There are two main serotypes both of which occur in two pathotypes, the avirulent enteric viruses and the virulent, usually fatal peritonitis viruses, the latter in turn occurring either in a 'wet' or exudative form or in a 'dry' or proliferative form. In this paper a concise overview is given of the molecular features of these viruses. Special attention is given to the genetic dynamics of the viruses as these now allow us to begin to understand the origin of the different phenotypes, in particular the genesis of virulence during persistent infection. As discussed, the surprising new insights obtained over the last few years call for a critical reevaluation of strategies for protection. Copyright (C) 1999 Elsevier Science B. V.
keywords
๐ peritonitis virus (67)
author
๐ค Rottier, Peter J.M.
year
โฐ 1999
journal
๐ Veterinary Microbiology
issn
๐ 03781135
volume
69
number
1-2
page
117-125
citedbycount
19
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