π€ Rottier, Peter J.M.
Keywords
Articles (62)
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Cathepsin L functionally cleaves the severe acute respiratory syndrome coronavirus class I fusion protein upstream of rather than adjacent to the fusion peptide
π€ Bosch, Berend Jan π€ Bartelink, Willem π€ Rottier, Peter J.M. β° 2008 π Journal of Virology
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Coronavirus spike glycoprotein, extended at the carboxy terminus with green fluorescent protein, is assembly competent
π€ Bosch, Berend Jan π€ De Haan, Cornelis A.M. π€ Rottier, Peter J.M. β° 2004 π Journal of Virology
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Spike protein assembly into the coronavirion: Exploring the limits of its sequence requirements
π€ Bosch, Berend Jan π€ De Haan, Cornelis A.M. π€ Smits, Saskia L. π€ Rottier, Peter J.M. β° 2005 π Virology
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Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides
π€ Bosch, Berend Jan π€ Martina, Byron E.E. π€ Van Der Zee, Ruurd π€ Lepault, Jean π€ Haijema, Bert Jan π€ Versluis, Cees π€ Heck, Albert J.R. π€ De Groot, Raoul π€ Osterhaus, Albert D.M.E. π€ Rottier, Peter J.M. β° 2004 π Proceedings of the National Academy of Sciences of the United States of America
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Coronavirus escape from Heptad Repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein
π€ Bosch, Berend Jan π€ Rossen, John W.A. π€ Bartelink, Willem π€ Zuurveen, Stephanie J. π€ De Haan, Cornelis A.M. π€ Duquerroy, Stephane π€ Boucher, Charles A.B. π€ Rottier, Peter J.M. β° 2008 π Journal of Virology
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The coronavirus spike protein is a class I virus fusion protein: Structural and functional characterization of the fusion core complex
π€ Bosch, Berend Jan π€ Van der Zee, Ruurd π€ De Haan, Cornelis A.M. π€ Rottier, Peter J.M. β° 2003 π Journal of Virology
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ATP1A1-mediated Src signaling inhibits coronavirus entry into host cells
π€ Burkard, Christine π€ Verheije, Monique H. π€ Haagmans, Bart L. π€ van Kuppeveld, Frank J. π€ Rottier, Peter J.M. π€ Bosch, Berend Jan π€ de Haan, Cornelis A.M. β° 2015 π Journal of Virology
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Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner
π€ Burkard, Christine π€ Verheije, Monique H. π€ Wicht, Oliver π€ van Kasteren, Sander I. π€ van Kuppeveld, Frank J. π€ Haagmans, Bart L. π€ Pelkmans, Lucas π€ Rottier, Peter J.M. π€ Bosch, Berend Jan π€ de Haan, Cornelis A.M. β° 2014 π PLoS Pathogens
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Cryo-electron tomography of mouse hepatitis virus: Insights into the structure of the coronavirion
π€ BΓ‘rcena, Montserrat π€ Oostergetel, Gert T. π€ Bartelink, Willem π€ Faas, Frank G.A. π€ Verkleij, Arie π€ Rottier, Peter J.M. π€ Koster, Abraham J. π€ Bosch, Berend Jan β° 2009 π Proceedings of the National Academy of Sciences of the United States of America
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Feline infectious peritonitis: Insights into feline coronavirus pathobiogenesis and epidemiology based on genetic analysis of the viral 3c gene
π€ Chang, Hui Wen π€ de Groot, Raoul J. π€ Egberink, Herman F. π€ Rottier, Peter J.M. β° 2010 π Journal of General Virology
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The glycosylation status of the murine hepatitis coronavirus M protein affects the interferogenic capacity of the virus in vitro and its ability to replicate in the liver but not the brain
π€ De Haan, Cornelis A.M. π€ De Wit, MarΓ¨l π€ Kuo, Lili π€ Montalto-Morrison, Cynthia π€ Haagmans, Bart L. π€ Weiss, Susan R. π€ Masters, Paul S. π€ Rottier, Peter J.M. β° 2003 π Virology
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Coronaviruses as vectors: Stability of foreign gene expression
π€ De Haan, Cornelis A.M. π€ Haijema, Bert Jan π€ Boss, David π€ Heuts, Frank W.H. π€ Rottier, Peter J.M. β° 2005 π Journal of Virology
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Murine coronavirus with an extended host range uses heparan sulfate as an entry receptor
π€ De Haan, Cornelis A.M. π€ Li, Zhen π€ Te Lintelo, Eddie π€ Bosch, Berend Jan π€ Haijema, Bert Jan π€ Rottier, Peter J.M. β° 2005 π Journal of Virology
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The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host
π€ De Haan, Cornelis A.M. π€ Masters, Paul S. π€ Shen, Xiaolan π€ Weiss, Susan π€ Rottier, Peter J.M. β° 2002 π Virology
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Hosting the severe acute respiratory syndrome coronavirus: Specific cell factors required for infection
π€ de Haan, Cornelis A.M. π€ Rottier, Peter J.M. β° 2006 π Cellular Microbiology
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Cleavage inhibition of the murine coronavirus spike protein by a furin-like enzyme affects cell-cell but not virus-cell fusion
π€ De Haan, Cornelis A.M. π€ Stadler, Konrad π€ Godeke, Gert Jan π€ Bosch, Berend Jan π€ Rottier, Peter J.M. β° 2004 π Journal of Virology
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Cooperative involvement of the S1 and S2 subunits of the murine coronavirus spike protein in receptor binding and extended host range
π€ De Haan, Cornelis A.M. π€ Te Lintelo, Eddie π€ Li, Zhen π€ Raaben, Matthijs π€ Wurdinger, Tom π€ Bosch, Berend Jan π€ Rottier, Peter J.M. β° 2006 π Journal of Virology
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Coronaviruses as Vectors: Position Dependence of Foreign Gene Expression
π€ De Haan, Cornelis A.M. π€ Van Genne, Linda π€ Stoop, Jeroen N. π€ Volders, Haukeline π€ Rottier, Peter J.M. β° 2003 π Journal of Virology
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Assembly of the coronavirus envelope: Homotypic interactions between the M proteins
π€ De Haan, Cornelis A.M. π€ Vennema, Harry π€ Rottier, Peter J.M. β° 2000 π Journal of Virology
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Coronaviruses maintain viability despite dramatic rearrangements of the strictly conserved genome organization
π€ De Haan, Cornelis A.M. π€ Volders, Haukeline π€ Koetzner, Cheri A. π€ Masters, Paul S. π€ Rottier, Peter J.M. β° 2002 π Journal of Virology
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The genome organization of the nidovirales: Similarities and differences between arteri-, toro-, and coronaviruses
π€ De Vries, Antoine A.F. π€ Horzinek, Marian C. π€ Rottier, Peter J.M. π€ De Groot, Raoul J. β° 1997 π Seminars in Virology
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Central ions and lateral asparagine/glutamine zippers stabilize the post-fusion hairpin conformation of the SARS coronavirus spike glycoprotein
π€ Duquerroy, StΓ©phane π€ Vigouroux, Armelle π€ Rottier, Peter J.M. π€ Rey, FΓ©lix A. π€ Jan Bosch, Berend β° 2005 π Virology
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Assembly of spikes into coronavirus particles is mediated by the carboxy-terminal domain of the spike protein
π€ Godeke, Gert Jan π€ De Haan, Cornelis A.M. π€ Rossen, John W.A. π€ Vennema, Harry π€ Rottier, Peter J.M. β° 2000 π Journal of Virology
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Membrane rearrangements mediated by coronavirus nonstructural proteins 3 and 4
π€ Hagemeijer, Marne C. π€ Monastyrska, Iryna π€ Griffith, Janice π€ van der Sluijs, Peter π€ Voortman, Jarno π€ van Bergen en Henegouwen, Paul M. π€ Vonk, Annelotte M. π€ Rottier, Peter J.M. π€ Reggiori, Fulvio π€ De Haan, Cornelis A.M. β° 2014 π Virology
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Biogenesis and dynamics of the coronavirus replicative structures
π€ Hagemeijer, Marne C. π€ Rottier, Peter J.M. π€ de Haan, Cornelis A.M. β° 2012 π Viruses
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Mobility and interactions of coronavirus nonstructural protein 4
π€ Hagemeijer, Marne C. π€ Ulasli, Mustafa π€ Vonk, Annelotte M. π€ Reggiori, Fulvio π€ Rottier, Peter J.M. π€ de Haan, Cornelis A.M. β° 2011 π Journal of Virology
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Dynamics of coronavirus replication-transcription complexes
π€ Hagemeijer, Marne C. π€ Verheije, Monique H. π€ Ulasli, Mustafa π€ ShaltiΓ«, Indra A. π€ De Vries, Lisa A. π€ Reggiori, Fulvio π€ Rottier, Peter J.M. π€ De Haan, Cornelis A.M. β° 2010 π Journal of Virology
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Visualizing coronavirus RNA synthesis in time by using click chemistry
π€ Hagemeijer, Marne C. π€ Vonk, Annelotte M. π€ Monastyrska, Iryna π€ Rottier, Peter J.M. π€ de Haan, Cornelis A.M. β° 2012 π Journal of Virology
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Switching species tropism: An effective way to manipulate the feline coronavirus genome
π€ Haijema, Bert Jan π€ Volders, Haukeliene π€ Rottier, Peter J.M. β° 2003 π Journal of Virology
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Live, Attenuated Coronavirus Vaccines through the Directed Deletion of Group-Specific Genes Provide Protection against Feline Infectious Peritonitis
π€ Haijema, Bert Jan π€ Volders, Haukeline π€ Rottier, Peter J.M. β° 2004 π Journal of Virology
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The molecular genetics of feline coronaviruses: Comparative sequence analysis of the ORF7a/7b transcription unit of different biotypes
π€ Herrewegh, Arnold A.P.M. π€ Vennema, Harry π€ Horzinek, Marian C. π€ Rottier, Peter J.M. π€ De Groot, Raoul J. β° 1995 π Virology
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SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells
π€ Huang, I. Chueh π€ Bosch, Berend Jan π€ Li, Fang π€ Li, Wenhui π€ Kyoung, Hoa Lee π€ Ghiran, Sorina π€ Vasilieva, Natalya π€ Dermody, Terence S. π€ Harrison, Stephen C. π€ Dormitzer, Philip R. π€ Farzan, Michael π€ Rottier, Peter J.M. π€ Choe, Hyeryun β° 2006 π Journal of Biological Chemistry
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Retargeting of coronavirus by substitution of the spike glycoprotein ectodomain: Crossing the host cell species barrier
π€ Kuo, Lili π€ Godeke, Gert Jan π€ Raamsman, Martin J.B. π€ Masters, Paul S. π€ Rottier, Peter J.M. β° 2000 π Journal of Virology
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A single point mutation creating a furin cleavage site in the spike protein renders porcine epidemic diarrhea coronavirus trypsin independent for cell entry and fusion
π€ Li, Wentao π€ Wicht, Oliver π€ van Kuppeveld, Frank J.M. π€ He, Qigai π€ Rottier, Peter J.M. π€ Bosch, Berend Jan β° 2015 π Journal of Virology
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Gain, preservation, and loss of a group 1a coronavirus accessory glycoprotein
π€ Lorusso, Alessio π€ Decaro, Nicola π€ Schellen, Pepijn π€ Rottier, Peter J.M. π€ Buonavoglia, Canio π€ Haijema, Bert Jan π€ De Groot, Raoul J. β° 2008 π Journal of Virology
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The receptor binding domain of the new middle east respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies
π€ Mou, Huihui π€ Raj, V. Stalin π€ Van Kuppeveld, Frank J.M. π€ Rottier, Peter J.M. π€ Haagmans, Bart L. π€ Bosch, Berend Jan β° 2013 π Journal of Virology
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The 29-nucleotide deletion present in human but not in animal severe acute respiratory syndrome coronaviruses disrupts the functional expression of open reading frame 8
π€ Oostra, Monique π€ De Haan, Cornelis A.M. π€ Rottier, Peter J.M. β° 2007 π Journal of Virology
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Topology and membrane anchoring of the coronavirus replication complex: Not all hydrophobic domains of nsp3 and nsp6 are membrane spanning
π€ Oostra, Monique π€ Hagemeijer, Marne C. π€ Van Gent, Michiel π€ Bekker, Cornelis P.J. π€ Te Lintelo, Eddie G. π€ Rottier, Peter J.M. π€ De Haan, Cornelis A.M. β° 2008 π Journal of Virology
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Envelope glycoprotein interactions in coronavirus assembly
π€ Opstelten, Dirk Jan E. π€ Raamsman, Martin J.B. π€ Wolfs, Karin π€ Horzinek, Marian C. π€ Rottier, Peter J.M. β° 1995 π Journal of Cell Biology
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The proteasome inhibitor velcade enhances rather than reduces disease in mouse hepatitis coronavirus-infected mice
π€ Raaben, Matthijs π€ Grinwis, Guy C.M. π€ Rottier, Peter J.M. π€ De Haan, Cornelis A.M. β° 2010 π Journal of Virology
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Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies
π€ Raaben, Matthijs π€ Groot Koerkamp, Marian J.A. π€ Rottier, Peter J.M. π€ de Haan, Cornelis A.M. β° 2007 π Cellular Microbiology
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Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo
π€ Raaben, Matthijs π€ Groot Koerkamp, Marian J.A. π€ Rottier, Peter J.M. π€ de Haan, Cornelis A.M. β° 2009 π BMC Genomics
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The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle
π€ Raaben, Matthijs π€ Posthuma, Clara C. π€ Verheije, Monique H. π€ Te Lintelo, Eddie G. π€ Kikkert, Marjolein π€ Drijfhout, Jan W. π€ Snijder, Eric J. π€ Rottier, Peter J.M. π€ De Haan, Cornelis A.M. β° 2010 π Journal of Virology
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Non-invasive imaging of mouse hepatitis coronavirus infection reveals determinants of viral replication and spread in vivo
π€ Raaben, Matthijs π€ Prins, Henk Jan π€ Martens, Anton C. π€ Rottier, Peter J.M. π€ de Haan, Cornelis A.M. β° 2009 π Cellular Microbiology
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Characterization of the coronavirus mouse hepatitis virus strain A59 small membrane protein E
π€ Raamsman, Martin J.B. π€ Krijnse Locker, Jacomine π€ De Hooge, Alphons π€ De Vries, Antoine A.F. π€ Griffiths, Gareth π€ Vennema, Harry π€ Rottier, Peter J.M. β° 2000 π Journal of Virology
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Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
π€ Raj, V. Stalin π€ Mou, Huihui π€ Smits, Saskia L. π€ Dekkers, Dick H.W. π€ MΓΌller, Marcel A. π€ Dijkman, Ronald π€ Muth, Doreen π€ Demmers, Jeroen A.A. π€ Zaki, Ali π€ Fouchier, Ron A.M. π€ Thiel, Volker π€ Drosten, Christian π€ Rottier, Peter J.M. π€ Osterhaus, Albert D.M.E. π€ Bosch, Berend Jan π€ Haagmans, Bart L. β° 2013 π Nature
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The molecular dynamics of feline coronaviruses
π€ Rottier, Peter J.M. β° 1999 π Veterinary Microbiology
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Acquisition of macrophage tropism during the pathogenesis of feline infectious peritonitis is determined by mutations in the feline coronavirus spike protein
π€ Rottier, Peter J.M. π€ Nakamura, Kazuya π€ Schellen, Pepijn π€ Volders, Haukeline π€ Haijema, Bert Jan β° 2005 π Journal of Virology
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Predicted Membrane Topology of the Coronavirus Protein E1
π€ Rottier, Peter J.M. π€ Niesters, Hubert G.M. π€ Lenstra, Johannes A. π€ Van der Zeijst, Bernard A.M. π€ Welling, Gjalt W. π€ Welling-Wester, Sytske β° 1986 π Biochemistry
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Differential susceptibility of macrophages to serotype II feline coronaviruses correlates with differences in the viral spike protein
π€ Shirato, Kazuya π€ Chang, Hui Wen π€ Rottier, Peter J.M. β° 2018 π Virus Research
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Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the middle East respiratory syndrome coronavirus
π€ Stalin Raj, V. π€ Smits, Saskia L. π€ Provacia, Lisette B. π€ van den Brand, Judith M.A. π€ Wiersma, Lidewij π€ Ouwendijk, Werner J.D. π€ Bestebroer, Theo M. π€ Spronken, Monique I. π€ van Amerongen, Geert π€ Rottier, Peter J.M. π€ Fouchier, Ron A.M. π€ Bosch, Berend Jan π€ Osterhaus, Albert D.M.E. π€ Haagmans, Bart L. β° 2014 π Journal of Virology
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Recombinant live attenuated avian coronavirus vaccines with deletions in the accessory genes 3ab and/or 5ab protect against infectious bronchitis in chickens
π€ van Beurden, Steven J. π€ Berends, Alinda J. π€ KrΓ€mer-KΓΌhl, Annika π€ Spekreijse, Dieuwertje π€ Chenard, Gilles π€ Philipp, Hans Christian π€ Mundt, Egbert π€ Rottier, Peter J.M. π€ Verheije, M. HΓ©lΓ¨ne β° 2018 π Vaccine
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A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination
π€ Van Beurden, Steven J. π€ Berends, Alinda J. π€ KrΓ€mer-KΓΌhl, Annika π€ Spekreijse, Dieuwertje π€ ChΓ©nard, Gilles π€ Philipp, Hans Christian π€ Mundt, Egbert π€ Rottier, Peter J.M. π€ Verheije, M. HΓ©lΓ¨ne β° 2017 π Virology Journal
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The coronavirus nucleocapsid protein is dynamically associated with the replication-transcription complexes
π€ Verheije, Monique H. π€ Hagemeijer, Marne C. π€ Ulasli, Mustafa π€ Reggiori, Fulvio π€ Rottier, Peter J.M. π€ Masters, Paul S. π€ De Haan, Cornelis A.M. β° 2010 π Journal of Virology
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Coronavirus genetically redirected to the epidermal growth factor receptor exhibits effective antitumor activity against a malignant glioblastoma
π€ Verheije, Monique H. π€ Lamfers, Martine L.M. π€ WΓΌrdinger, Thomas π€ Grinwis, Guy C.M. π€ Gerritsen, Winald R. π€ Van Beusechem, Victor W. π€ Rottier, Peter J.M. β° 2009 π Journal of Virology
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Mouse hepatitis coronavirus RNA replication depends on GBF1-mediated ARF1 activation
π€ Verheije, Monique H. π€ Raaben, Matthijs π€ Mari, Muriel π€ Te Lintelo, Eddie G. π€ Reggiori, Fulvio π€ Van Kuppeveld, Frank J.M. π€ Rottier, Peter J.M. π€ De Haan, Cornelis A.M. β° 2008 π PLoS Pathogens
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Pathogenic characteristics of persistent feline enteric coronavirus infection in cats
π€ Vogel, Liesbeth π€ Van Der Lubben, Mariken π€ Te Lintelo, Eddie G. π€ Bekker, Cornelis P.J. π€ Geerts, Tamara π€ Schuijff, Leontine S. π€ Grinwis, Guy C.M. π€ Egberink, Herman F. π€ Rottier, Peter J.M. β° 2010 π Veterinary Research
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Identification of host factors involved in coronavirus replication by quantitative proteomics analysis
π€ Vogels, Mijke W. π€ Van Balkom, Bas W.M. π€ Kaloyanova, Dora V. π€ Batenburg, Joseph J. π€ Heck, Albert J. π€ Helms, J. Bernd π€ Rottier, Peter J.M. π€ De Haan, Cornelis A.M. β° 2011 π Proteomics
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Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo-electron microscopy
π€ Walls, Alexandra π€ Tortorici, M. Alejandra π€ Bosch, Berend Jan π€ Frenz, Brandon π€ Rottier, Peter J.M. π€ DiMaio, Frank π€ Rey, Felix A. π€ Veesler, David β° 2017 π Protein Science
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Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer
π€ Walls, Alexandra C. π€ Tortorici, M. Alejandra π€ Bosch, Berend Jan π€ Frenz, Brandon π€ Rottier, Peter J.M. π€ DiMaio, Frank π€ Rey, FΓ©lix A. π€ Veesler, David β° 2016 π Nature
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Identification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell
π€ Wicht, Oliver π€ Burkard, Christine π€ de Haan, Cornelis A.M. π€ van Kuppeveld, Frank J.M. π€ Rottier, Peter J.M. π€ Bosch, Berend Jan β° 2014 π Journal of Virology
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Proteolytic activation of the porcine epidemic diarrhea coronavirus spike fusion protein by trypsin in cell culture
π€ Wicht, Oliver π€ Li, Wentao π€ Willems, Lione π€ Meuleman, Tom J. π€ Wubbolts, Richard W. π€ van Kuppeveld, Frank J.M. π€ Rottier, Peter J.M. π€ Bosch, Berend Jan β° 2014 π Journal of Virology