🔗 Converting enzyme
Articles (162)
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Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms
👤 Adedeji, Adeyemi O. 👤 Severson, William 👤 Jonsson, Colleen 👤 Singh, Kamalendra 👤 Weiss, Susan R. 👤 Sarafianosa, Stefan G. ⏰ 2013 📚 Journal of Virology
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Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host-Virus Interaction, and Proposed Neurotropic Mechanisms.
👤 Baig, Abdul Mannan 👤 Khaleeq, Areeba 👤 Ali, Usman 👤 Syeda, Hira ⏰ 2020 📚 ACS Chem Neurosci
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Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?
👤 Batlle, Daniel 👤 Wysocki, Jan 👤 Satchell, Karla ⏰ 2020 📚 Clin Sci (Lond)
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Conformational reorganization of the SARS coronavirus spike following receptor binding: Implications for membrane fusion
👤 Beniac, Daniel R. 👤 de Varennes, Shauna L. 👤 Andonov, Anton 👤 He, Runtao 👤 Booth, Tim F. ⏰ 2007 📚 PLoS ONE
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Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease
👤 Bertram, Stephanie 👤 Glowacka, Ilona 👤 Müller, Marcel A. 👤 Lavender, Hayley 👤 Gnirss, Kerstin 👤 Nehlmeier, Inga 👤 Niemeyer, Daniela 👤 He, Yuxian 👤 Simmons, Graham 👤 Drosten, Christian 👤 Soilleux, Elizabeth J. 👤 Jahn, Olaf 👤 Steffen, Imke 👤 Pöhlmann, Stefan ⏰ 2011 📚 Journal of Virology
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Membrane ectopeptidases targeted by human coronaviruses
👤 Bosch, Berend Jan 👤 Smits, Saskia L. 👤 Haagmans, Bart L. ⏰ 2014 📚 Current Opinion in Virology
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Smoking Upregulates Angiotensin-Converting Enzyme-2 Receptor: A Potential Adhesion Site for Novel Coronavirus SARS-CoV-2 (Covid-19).
👤 Brake, Samuel James 👤 Barnsley, Kathryn 👤 Lu, Wenying 👤 McAlinden, Kielan Darcy 👤 Eapen, Mathew Suji 👤 Sohal, Sukhwinder Singh ⏰ 2020 📚 J Clin Med
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In Silico Discovery of Candidate Drugs against Covid-19.
👤 Cava, Claudia 👤 Bertoli, Gloria 👤 Castiglioni, Isabella ⏰ 2020 📚 Viruses
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Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility.
👤 Chan, Jasper Fuk-Woo 👤 Zhang, Anna Jinxia 👤 Yuan, Shuofeng 👤 Poon, Vincent Kwok-Man 👤 Chan, Chris Chung-Sing 👤 Lee, Andrew Chak-Yiu 👤 Chan, Wan-Mui 👤 Fan, Zhimeng 👤 Tsoi, Hoi-Wah 👤 Wen, Lei 👤 Liang, Ronghui 👤 Cao, Jianli 👤 Chen, Yanxia 👤 Tang, Kaiming 👤 Luo, Cuiting 👤 Cai, Jian-Piao 👤 Kok, Kin-Hang 👤 Chu, Hin 👤 Chan, Kwok-Hung 👤 Sridhar, Siddharth 👤 Chen, Zhiwei 👤 Chen, Honglin 👤 To, Kelvin Kai-Wang 👤 Yuen, Kwok-Yung ⏰ 2020 📚 Clin Infect Dis
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Persistent infection of SARS coronavirus in colonic cells in vitro
👤 Chan, Paul K.S. 👤 To, Ka Fai 👤 Lo, Anthony W.I. 👤 Cheung, Jo L.K. 👤 Chu, Ida 👤 Au, Florence W.L. 👤 Tong, Joanna H.M. 👤 Tam, John S. 👤 Sung, Joseph J.Y. 👤 Ng, Ho Keung ⏰ 2004 📚 Journal of Medical Virology
- The emergence of human coronavirus EMC: How scared should we be?
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Induction of IL-8 release in lung cells via activator protein-1 by recombinant baculovirus displaying severe acute respiratory syndrome-coronavirus spike proteins: Identification of two functional regions
👤 Chang, Ya Jen 👤 Liu, Catherine Y.Y. 👤 Chiang, Bor Luen 👤 Chao, Yu Chan 👤 Chen, Ching Chow ⏰ 2004 📚 Journal of Immunology
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Upregulation of the chemokine (C-C Motif) Ligand 2 via a severe acute respiratory syndrome coronavirus spike-ACE2 signaling pathway
👤 Chen, I. Yin 👤 Chang, Shin C. 👤 Wu, Hung Yi 👤 Yu, Ting Chun 👤 Wei, Wen Chin 👤 Lin, Shiming 👤 Chien, Chung Liang 👤 Chang, Ming Fu ⏰ 2010 📚 Journal of Virology
- The role of angiotensin-converting enzyme 2 in coronaviruses/influenza viruses and cardiovascular disease.
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The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2.
👤 Chen, Liang 👤 Li, Xiangjie 👤 Chen, Mingquan 👤 Feng, Yi 👤 Xiong, Chenglong ⏰ 2020 📚 Cardiovasc Res
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A novel subset of putative stem/progenitor CD34+ Oct-4 + cells is the major target for SARS coronavirus in human lung
👤 Chen, Yongxiong 👤 Chan, Vera Sau Fong 👤 Zheng, Bojian 👤 Chan, Kelvin Yuen Kwong 👤 Xu, Xiaoning 👤 To, Leo Yuk Fai 👤 Huang, Fang Ping 👤 Khoo, Ui Soon 👤 Lin, Chen Lung Steve ⏰ 2007 📚 Journal of Experimental Medicine
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Structure analysis of the receptor binding of 2019-nCoV.
👤 Chen, Yun 👤 Guo, Yao 👤 Pan, Yihang 👤 Zhao, Zhizhuang Joe ⏰ 2020 📚 Biochem Biophys Res Commun
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Rhesus angiotensin converting enzyme 2 supports entry of severe acute respiratory syndrome coronavirus in Chinese macaques
👤 Chen, Yunxin 👤 Liu, Li 👤 Wei, Qiang 👤 Zhu, Hua 👤 Jiang, Hong 👤 Tu, Xinming 👤 Qin, Chuan 👤 Chen, Zhiwei ⏰ 2008 📚 Virology
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Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region
👤 Chen, Zhiwei 👤 Zhang, Linqi 👤 Qin, Chuan 👤 Ba, Lei 👤 Yi, Christopher E. 👤 Zhang, Fengwen 👤 Wei, Qiang 👤 He, Tian 👤 Yu, Wenjie 👤 Yu, Jian 👤 Gao, Hong 👤 Tu, Xinming 👤 Gettie, Agegnehu 👤 Farzan, Michael 👤 Yuen, Kwok Yung 👤 Ho, David D. ⏰ 2005 📚 Journal of Virology
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Organ-protective effect of angiotensin-converting enzyme 2 and its effect on the prognosis of COVID-19.
👤 Cheng, Hao 👤 Wang, Yan 👤 Wang, Gui-Qiang ⏰ 2020 📚 J Med Virol
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The use of hepatitis C virus NS3/4A and secreted alkaline phosphatase to quantitate cell-cell membrane fusion mediated by severe acute respiratory syndrome coronavirus S protein and the receptor angiotensin-converting enzyme 2
👤 Chou, Chih Fong 👤 Shen, Shuo 👤 Mahadevappa, Geetha 👤 Lim, Seng Gee 👤 Hong, Wanjin 👤 Tan, Yee Joo ⏰ 2007 📚 Analytical Biochemistry
- Coronavirus COV-19/SARS-CoV-2 affects women less than men: clinical response to viral infection.
- Comment on "Organ-protective Effect of Angiotensin-converting Enzyme 2 and its Effect on the Prognosis of COVID-19".
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Renin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers.
👤 Danser, A H Jan 👤 Epstein, Murray 👤 Batlle, Daniel ⏰ 2020 📚 Hypertension
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Interferon-γ and interleukin-4 downregulate expression of the SARS coronavirus receptor ACE2 in Vero E6 cells
👤 de Lang, Anna 👤 Osterhaus, Albert D.M.E. 👤 Haagmans, Bart L. ⏰ 2006 📚 Virology
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Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice
👤 DeDiego, Marta L. 👤 Pewe, Lecia 👤 Alvarez, Enrique 👤 Rejas, Maria Teresa 👤 Perlman, Stanley 👤 Enjuanes, Luis ⏰ 2008 📚 Virology
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Evidence for ACE2-utilizing coronaviruses (covs) related to severe acute respiratory syndrome cov in bats
👤 Demogines, Ann 👤 Farzan, Michael 👤 Sawyer, Sara L. ⏰ 2012 📚 Journal of Virology
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Hypothesis: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19.
👤 Diaz, James H ⏰ 2020 📚 J Travel Med
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Replication-dependent downregulation of cellular angiotensin-converting enzyme 2 protein expression by human coronavirus NL63
👤 Dijkman, Ronald 👤 Jebbink, Maarten F. 👤 Deijs, Martin 👤 Milewska, Aleksandra 👤 Pyrc, Krzysztof 👤 Buelow, Elena 👤 van der Bijl, Anna 👤 van der Hoek, Lia ⏰ 2012 📚 Journal of General Virology
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Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus (2019-nCoV) related coronavirus model.
👤 Fan, Hua-Hao 👤 Wang, Li-Qin 👤 Liu, Wen-Li 👤 An, Xiao-Ping 👤 Liu, Zhen-Dong 👤 He, Xiao-Qi 👤 Song, Li-Hua 👤 Tong, Yi-Gang ⏰ 2020 📚 Chin Med J (Engl)
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Reconstitution of the receptor-binding motif of the SARS coronavirus
👤 Freund, Natalia T. 👤 Roitburd-Berman, Anna 👤 Sui, Jianhua 👤 Marasco, Wayne A. 👤 Gershoni, Jonathan M. ⏰ 2015 📚 Protein Engineering, Design and Selection
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Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease
👤 Frieman, Matthew 👤 Yount, Boyd 👤 Agnihothram, Sudhakar 👤 Page, Carly 👤 Donaldson, Eric 👤 Roberts, Anjeanette 👤 Vogel, Leatrice 👤 Woodruff, Becky 👤 Scorpio, Diana 👤 Subbarao, Kanta 👤 Baric, Ralph S. ⏰ 2012 📚 Journal of Virology
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Vesicular stomatitis virus pseudotyped with severe acute respiratory syndrome coronavirus spike protein
👤 Fukushi, Shuetsu 👤 Mizutani, Tetsuya 👤 Saijo, Masayuki 👤 Matsuyama, Shutoku 👤 Miyajima, Naoko 👤 Taguchi, Fumihiro 👤 Itamura, Shigeyuki 👤 Kurane, Ichiro 👤 Morikawa, Shigeru ⏰ 2005 📚 Journal of General Virology
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Amino acid substitutions in the S2 region enhance severe acute respiratory syndrome coronavirus infectivity in rat angiotensin-converting enzyme 2-expressing cells
👤 Fukushi, Shuetsu 👤 Mizutani, Tetsuya 👤 Sakai, Kouji 👤 Saijo, Masayuki 👤 Taguchi, Fumihiro 👤 Yokoyama, Masaru 👤 Kurane, Ichiro 👤 Morikawa, Shigeru ⏰ 2007 📚 Journal of Virology
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Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
👤 Ge, Xing Yi 👤 Li, Jia Lu 👤 Yang, Xing Lou 👤 Chmura, Aleksei A. 👤 Zhu, Guangjian 👤 Epstein, Jonathan H. 👤 Mazet, Jonna K. 👤 Hu, Ben 👤 Zhang, Wei 👤 Peng, Cheng 👤 Zhang, Yu Ji 👤 Luo, Chu Ming 👤 Tan, Bing 👤 Wang, Ning 👤 Zhu, Yan 👤 Crameri, Gary 👤 Zhang, Shu Yi 👤 Wang, Lin Fa 👤 Daszak, Peter 👤 Shi, Zheng Li ⏰ 2013 📚 Nature
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Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System.
👤 Gheblawi, Mahmoud 👤 Wang, Kaiming 👤 Viveiros, Anissa 👤 Nguyen, Quynh 👤 Zhong, Jiu-Chang 👤 Turner, Anthony J 👤 Raizada, Mohan K 👤 Grant, Maria B 👤 Oudit, Gavin Y ⏰ 2020 📚 Circ Res
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Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice
👤 Glass, William G. 👤 Subbarao, Kanta 👤 Murphy, Brian 👤 Murphy, Philip M. ⏰ 2004 📚 Journal of Immunology
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Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2
👤 Glende, Joerg 👤 Schwegmann-Wessels, Christel 👤 Al-Falah, Marwan 👤 Pfefferle, Susanne 👤 Qu, Xiuxia 👤 Deng, Hongkui 👤 Drosten, Christian 👤 Naim, Hassan Y. 👤 Herrler, Georg ⏰ 2008 📚 Virology
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Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63
👤 Glowacka, Ilona 👤 Bertram, Stephanie 👤 Herzog, Petra 👤 Pfefferle, Susanne 👤 Steffen, Imke 👤 Muench, Marcus O. 👤 Simmons, Graham 👤 Hofmann, Heike 👤 Kuri, Thomas 👤 Weber, Friedemann 👤 Eichler, Jutta 👤 Drosten, Christian 👤 Pöhlmann, Stefan ⏰ 2010 📚 Journal of Virology
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Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19).
👤 Guo, Tao 👤 Fan, Yongzhen 👤 Chen, Ming 👤 Wu, Xiaoyan 👤 Zhang, Lin 👤 He, Tao 👤 Wang, Hairong 👤 Wan, Jing 👤 Wang, Xinghuan 👤 Lu, Zhibing ⏰ 2020 📚 JAMA Cardiol
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The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status.
👤 Guo, Yan-Rong 👤 Cao, Qing-Dong 👤 Hong, Zhong-Si 👤 Tan, Yuan-Yang 👤 Chen, Shou-Deng 👤 Jin, Hong-Jun 👤 Tan, Kai-Sen 👤 Wang, De-Yun 👤 Yan, Yan ⏰ 2020 📚 Mil Med Res
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Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics.
👤 Gurwitz, David ⏰ 2020 📚 Drug Dev Res
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Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis
👤 Hamming, I. 👤 Timens, W. 👤 Bulthuis, M. L.C. 👤 Lely, A. T. 👤 Navis, G. J. 👤 van Goor, H. ⏰ 2004 📚 Journal of Pathology
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Specific asparagine-linked glycosylation sites are critical for DC-SIGN- and L-SIGN-mediated severe acute respiratory syndrome coronavirus entry
👤 Han, Dong P. 👤 Lohani, Motashim 👤 Cho, Michael W. ⏰ 2007 📚 Journal of Virology
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Identification of diverse bat alphacoronaviruses and betacoronaviruses in china provides new insights into the evolution and origin of coronavirus-related diseases
👤 Han, Yelin 👤 Du, Jiang 👤 Su, Haoxiang 👤 Zhang, Junpeng 👤 Zhu, Guangjian 👤 Zhang, Shuyi 👤 Wu, Zhiqiang 👤 Jin, Qi ⏰ 2019 📚 Frontiers in Microbiology
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Is There an Association Between COVID-19 Mortality and the Renin-Angiotensin System-a Call for Epidemiologic Investigations.
👤 Hanff, Thomas C 👤 Harhay, Michael O 👤 Brown, Tyler S 👤 Cohen, Jordana B 👤 Mohareb, Amir M ⏰ 2020 📚 Clin Infect Dis
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Susceptibility of different eukaryotic cell lines to SARS-coronavirus
👤 Hattermann, K. 👤 Müller, M. A. 👤 Nitsche, A. 👤 Wendt, S. 👤 Donoso Mantke, O. 👤 Niedrig, M. ⏰ 2005 📚 Archives of Virology
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A single amino acid substitution (R441A) in the receptor-binding domain of SARS coronavirus spike protein disrupts the antigenic structure and binding activity
👤 He, Yuxian 👤 Li, Jingjing 👤 Jiang, Shibo ⏰ 2006 📚 Biochemical and Biophysical Research Communications
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Identification of a critical neutralization determinant of severe acute respiratory syndrome (SARS)-associated coronavirus: Importance for designing SARS vaccines
👤 He, Yuxian 👤 Zhu, Qingyu 👤 Liu, Shuwen 👤 Zhou, Yusen 👤 Yang, Baoan 👤 Li, Jiaming 👤 Jiang, Shibo ⏰ 2005 📚 Virology
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TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein
👤 Heurich, Adeline 👤 Hofmann-Winkler, Heike 👤 Gierer, Stefanie 👤 Liepold, Thomas 👤 Jahn, Olaf 👤 Pöhlmann, Stefan ⏰ 2014 📚 Journal of Virology
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Colonization of severe acute respiratory syndrome-associated coronavirus among health-care workers screened by nasopharyngeal swab
👤 Ho, Hsin Tsung 👤 Chang, Mau Sun 👤 Wei, Tsai Yin 👤 Hsieh, Wen Shyang 👤 Hung, Chia Chien 👤 Yang, Huei Mei 👤 Lu, Yen Ta ⏰ 2006 📚 Chest
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Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction
👤 Ho, Tin Yun 👤 Wu, Shih Lu 👤 Chen, Jaw Chyun 👤 Li, Chia Cheng 👤 Hsiang, Chien Yun ⏰ 2007 📚 Antiviral Research
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Susceptibility to SARS coronavirus S protein-driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor
👤 Hofmann, Heike 👤 Geier, Martina 👤 Marzi, Andrea 👤 Krumbiegel, Mandy 👤 Peipp, Matthias 👤 Fey, Georg H. 👤 Gramberg, Thomas 👤 Pöhlmann, Stefan ⏰ 2004 📚 Biochemical and Biophysical Research Communications
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Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry
👤 Hofmann, Heike 👤 Pyrc, Krzysztof 👤 Van Der Hoek, Lia 👤 Geier, Martina 👤 Berkhout, Ben 👤 Pöhlmann, Stefan ⏰ 2005 📚 Proceedings of the National Academy of Sciences of the United States of America
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Cellular entry of the SARS coronavirus
👤 Hofmann, Heike 👤 Pöhlmann, Stefan ⏰ 2004 📚 Trends in Microbiology
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Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors
👤 Hofmann, Heike 👤 Simmons, Graham 👤 Rennekamp, Andrew J. 👤 Chaipan, Chawaree 👤 Gramberg, Thomas 👤 Heck, Elke 👤 Geier, Martina 👤 Wegele, Anja 👤 Marzi, Andrea 👤 Bates, Paul 👤 Pöhlmann, Stefan ⏰ 2006 📚 Journal of Virology
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Aromatic amino acids in the juxtamembrane domain of severe acute respiratory syndrome coronavirus spike glycoprotein are important for receptor-dependent virus entry and cell-cell fusion
👤 Howard, Megan W. 👤 Travanty, Emily A. 👤 Jeffers, Scott A. 👤 Smith, M. K. 👤 Wennier, Sonia T. 👤 Thackray, Larissa B. 👤 Holmes, Kathryn V. ⏰ 2008 📚 Journal of Virology
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Screening and identification of linear B-cell epitopes and entry-blocking peptide of severe acute respiratory syndrome (SARS)-associated coronavirus using synthetic overlapping peptide library
👤 Hu, Hongbo 👤 Li, Li 👤 Kao, Richard Y. 👤 Kou, Binbin 👤 Wang, Zhanguo 👤 Zhang, Liang 👤 Zhang, Huiyuan 👤 Hao, Zhiyong 👤 Tsui, Wayne H. 👤 Ni, Anping 👤 Cui, Lianxian 👤 Fan, Baoxing 👤 Guo, Feng 👤 Rao, Shuan 👤 Jiang, Chengyu 👤 Li, Qian 👤 Sun, Manji 👤 He, Wei 👤 Liu, Gang ⏰ 2005 📚 Journal of Combinatorial Chemistry
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SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells
👤 Huang, I. Chueh 👤 Bosch, Berend Jan 👤 Li, Fang 👤 Li, Wenhui 👤 Kyoung, Hoa Lee 👤 Ghiran, Sorina 👤 Vasilieva, Natalya 👤 Dermody, Terence S. 👤 Harrison, Stephen C. 👤 Dormitzer, Philip R. 👤 Farzan, Michael 👤 Rottier, Peter J.M. 👤 Choe, Hyeryun ⏰ 2006 📚 Journal of Biological Chemistry
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Evolution of genomes, host shifts and the geographic spread of SARS-CoV and related coronaviruses
👤 Janies, Daniel 👤 Habib, Farhat 👤 Alexandrov, Boyan 👤 Hill, Andrew 👤 Pol, Diego ⏰ 2008 📚 Cladistics
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Anti-severe acute respiratory syndrome coronavirus spike antibodies trigger infection of human immune cells via a pH- and cysteine protease-independent Fcγr pathway
👤 Jaume, Martial 👤 Yip, Ming S. 👤 Cheung, Chung Y. 👤 Leung, Hiu L. 👤 Li, Ping H. 👤 Kien, Francois 👤 Dutry, Isabelle 👤 Callendret, Benoît 👤 Escriou, Nicolas 👤 Altmeyer, Ralf 👤 Nal, Beatrice 👤 Daëron, Marc 👤 Bruzzone, Roberto 👤 Peiris, J. S.Malik ⏰ 2011 📚 Journal of Virology
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CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus
👤 Jeffers, Scott A. 👤 Tusell, Sonia M. 👤 Gillim-Ross, Laura 👤 Hemmila, Erin M. 👤 Achenbach, Jenna E. 👤 Babcock, Gregory J. 👤 Thomas Jr., William D. 👤 Thackray, Larissa B. 👤 Young, Mark D. 👤 Mason, Robert J. 👤 Ambrosino, Donna M. 👤 Wentworth, David E. 👤 DeMartini, James C. 👤 Holmes, Kathryn V. ⏰ 2004 📚 Proceedings of the National Academy of Sciences of the United States of America
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ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia
👤 Jia, Hong Peng 👤 Look, Dwight C. 👤 Shi, Lei 👤 Hickey, Melissa 👤 Pewe, Lecia 👤 Netland, Jason 👤 Farzan, Michael 👤 Wohlford-Lenane, Christine 👤 Perlman, Stanley 👤 McCray Jr., Paul B. ⏰ 2005 📚 Journal of Virology
- Does COVID19 infect the brain? If so, smokers might be at a higher risk.
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A Comprehensive Literature Review on the Clinical Presentation, and Management of the Pandemic Coronavirus Disease 2019 (COVID-19).
👤 Kakodkar, Pramath 👤 Kaka, Nagham 👤 Baig, M N ⏰ 2020 📚 Cureus
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COVID-19 (Novel Coronavirus 2019) - recent trends.
👤 Kannan, S 👤 Shaik Syed Ali, P 👤 Sheeza, A 👤 Hemalatha, K ⏰ 2020 📚 Eur Rev Med Pharmacol Sci
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Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics
👤 Kao, Richard Y. 👤 Tsui, Wayne H.W. 👤 Lee, Terri S.W. 👤 Tanner, Julian A. 👤 Watt, Rory M. 👤 Huang, Jian Dong 👤 Hu, Lihong 👤 Chen, Guanhua 👤 Chen, Zhiwei 👤 Zhang, Linqi 👤 He, Tian 👤 Chan, Kwok Hung 👤 Tse, Herman 👤 To, Amanda P.C. 👤 Ng, Louisa W.Y. 👤 Wong, Bonnie C.W. 👤 Tsoi, Hoi Wah 👤 Yang, Dan 👤 Ho, David D. 👤 Yuen, Kwok Yung ⏰ 2004 📚 Chemistry and Biology
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Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry
👤 Kawase, Miyuki 👤 Shirato, Kazuya 👤 van der Hoek, Lia 👤 Taguchi, Fumihiro 👤 Matsuyama, Shutoku ⏰ 2012 📚 Journal of Virology
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Functional analysis of the receptor binding domain of SARS coronavirus S1 region and its monoclonal antibody
👤 Kim, Hyun 👤 Hong, Yeongjin 👤 Shibayama, Keigo 👤 Suzuki, Yasuhiko 👤 Wakamiya, Nobutaka 👤 Kim, Youn Uck ⏰ 2014 📚 Genes and Genomics
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Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
👤 Kirchdoerfer, Robert N. 👤 Wang, Nianshuang 👤 Pallesen, Jesper 👤 Wrapp, Daniel 👤 Turner, Hannah L. 👤 Cottrell, Christopher A. 👤 Corbett, Kizzmekia S. 👤 Graham, Barney S. 👤 McLellan, Jason S. 👤 Ward, Andrew B. ⏰ 2018 📚 Scientific Reports
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Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China.
👤 Kruse, Robert L ⏰ 2020 📚 F1000Res
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A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury
👤 Kuba, Keiji 👤 Imai, Yumiko 👤 Rao, Shuan 👤 Gao, Hong 👤 Guo, Feng 👤 Guan, Bin 👤 Huan, Yi 👤 Yang, Peng 👤 Zhang, Yanli 👤 Deng, Wei 👤 Bao, Linlin 👤 Zhang, Binlin 👤 Liu, Guang 👤 Wang, Zhong 👤 Chappell, Mark 👤 Liu, Yanxin 👤 Zheng, Dexian 👤 Leibbrandt, Andreas 👤 Wada, Teiji 👤 Slutsky, Arthur S. 👤 Liu, Depei 👤 Qin, Chuan 👤 Jiang, Chengyu 👤 Penninger, Josef M. ⏰ 2005 📚 Nature Medicine
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Tumor necrosis factor-α convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2)
👤 Lambert, Daniel W. 👤 Yarski, Mike 👤 Warner, Fiona J. 👤 Thornhill, Paul 👤 Parkin, Edward T. 👤 Smith, A. Ian 👤 Hooper, Nigel M. 👤 Turner, Anthony J. ⏰ 2005 📚 Journal of Biological Chemistry
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Development of human single-chain antibodies against SARS-associated coronavirus
👤 Leung, K. M. 👤 Feng, D. X. 👤 Lou, Jianlong 👤 Zhou, Yu 👤 Fung, K. P. 👤 Waye, Mary M.Y. 👤 Tsui, Stephen K.W. 👤 Chan, Paul K.S. 👤 Marks, James D. 👤 Pang, S. F. 👤 Kan, Y. W. ⏰ 2008 📚 Intervirology
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Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections
👤 Li, Fang ⏰ 2008 📚 Journal of Virology
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Receptor recognition and cross-species infections of SARS coronavirus
👤 Li, Fang ⏰ 2013 📚 Antiviral Research
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Structural biology: Structure of SARS coronavirus spike receptor-binding domain complexed with receptor
👤 Li, Fang 👤 Li, Wenhui 👤 Farzan, Michael 👤 Harrison, Stephen C. ⏰ 2005 📚 Science
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Lipid rafts play an important role in the early stage of severe acute respiratory syndrome-coronavirus life cycle
👤 Li, Gui Mei 👤 Li, Yong Gang 👤 Yamate, Masanobu 👤 Li, Shu Ming 👤 Ikuta, Kazuyoshi ⏰ 2007 📚 Microbes and Infection
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Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2
👤 Li, Wenhui 👤 Greenough, Thomas C. 👤 Moore, Michael J. 👤 Vasilieva, Natalya 👤 Somasundaran, Mohan 👤 Sullivan, John L. 👤 Farzan, Michael 👤 Choe, Hyeryun ⏰ 2004 📚 Journal of Virology
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Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
👤 Li, Wenhui 👤 Moore, Michael J. 👤 Vasllieva, Natalya 👤 Sui, Jianhua 👤 Wong, Swee Kee 👤 Berne, Michael A. 👤 Somasundaran, Mohan 👤 Sullivan, John L. 👤 Luzuriaga, Katherine 👤 Greeneugh, Thomas C. 👤 Choe, Hyeryun 👤 Farzan, Michael ⏰ 2003 📚 Nature
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The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2
👤 Li, Wenhui 👤 Sui, Jianhua 👤 Huang, I. Chueh 👤 Kuhn, Jens H. 👤 Radoshitzky, Sheli R. 👤 Marasco, Wayne A. 👤 Choe, Hyeryun 👤 Farzan, Michael ⏰ 2007 📚 Virology
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Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2
👤 Li, Wenhui 👤 Zhang, Chengsheng 👤 Sui, Jianhua 👤 Kuhn, Jens H. 👤 Moore, Michael J. 👤 Luo, Shiwen 👤 Wong, Swee Kee 👤 Huang, I. Chueh 👤 Xu, Keming 👤 Vasilieva, Natalya 👤 Murakami, Akikazu 👤 He, Yaqing 👤 Marasco, Wayne A. 👤 Guan, Yi 👤 Choe, Hyeryun 👤 Farzan, Michael ⏰ 2005 📚 EMBO Journal
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Identification of residues in the receptor-binding domain (RBD) of the spike protein of human coronavirus NL63 that are critical for the RBD-ACE2 receptor interaction
👤 Lin, Han Xin 👤 Feng, Yan 👤 Wong, Gillian 👤 Wang, Liping 👤 Li, Bei 👤 Zhao, Xuesen 👤 Li, Yan 👤 Smaill, Fiona 👤 Zhang, Chengsheng ⏰ 2008 📚 Journal of General Virology
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Identification of pulmonary Oct-4+ stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro
👤 Ling, Thai Yen 👤 Kuo, Ming Der 👤 Li, Chung Leung 👤 Yu, Alice L. 👤 Huang, Yen Hua 👤 Wu, Tsai Jung 👤 Lin, You Chin 👤 Chen, Shu Hwa 👤 Yu, John ⏰ 2006 📚 Proceedings of the National Academy of Sciences of the United States of America
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Natural mutations in the receptor binding domain of spike glycoprotein determine the reactivity of cross-neutralization between palm civet coronavirus and severe acute respiratory syndrome coronavirus
👤 Liu, Li 👤 Fang, Qing 👤 Deng, Fei 👤 Wang, Hanzhong 👤 Yi, Christopher E. 👤 Ba, Lei 👤 Yu, Wenjie 👤 Lin, Richard D. 👤 Li, Taisheng 👤 Hu, Zhihong 👤 Ho, David D. 👤 Zhang, Linqi 👤 Chen, Zhiwei ⏰ 2007 📚 Journal of Virology
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Epithelial cells lining salivary gland ducts are early target cells of severe acute respiratory syndrome coronavirus infection in the upper respiratory tracts of rhesus macaques
👤 Liu, Li 👤 Wei, Qiang 👤 Alvarez, Xavier 👤 Wang, Haibo 👤 Du, Yanhua 👤 Zhu, Hua 👤 Jiang, Hong 👤 Zhou, Jingying 👤 Lam, Pokman 👤 Zhang, Linqi 👤 Lackner, Andrew 👤 Qin, Chuan 👤 Chen, Zhiwei ⏰ 2011 📚 Journal of Virology
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Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2.
👤 Liu, Zhixin 👤 Xiao, Xiao 👤 Wei, Xiuli 👤 Li, Jian 👤 Yang, Jing 👤 Tan, Huabing 👤 Zhu, Jianyong 👤 Zhang, Qiwei 👤 Wu, Jianguo 👤 Liu, Long ⏰ 2020 📚 J Med Virol
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siRNA silencing of angiotensin-converting enzyme 2 reduced severe acute respiratory syndrome-associated coronavirus replications in Vero E6 cells
👤 Lu, C. Y. 👤 Huang, H. Y. 👤 Yang, T. H. 👤 Chang, L. Y. 👤 Lee, C. Y. 👤 Huang, L. M. ⏰ 2008 📚 European Journal of Clinical Microbiology and Infectious Diseases
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Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.
👤 Lu, Roujian 👤 Zhao, Xiang 👤 Li, Juan 👤 Niu, Peihua 👤 Yang, Bo 👤 Wu, Honglong 👤 Wang, Wenling 👤 Song, Hao 👤 Huang, Baoying 👤 Zhu, Na 👤 Bi, Yuhai 👤 Ma, Xuejun 👤 Zhan, Faxian 👤 Wang, Liang 👤 Hu, Tao 👤 Zhou, Hong 👤 Hu, Zhenhong 👤 Zhou, Weimin 👤 Zhao, Li 👤 Chen, Jing 👤 Meng, Yao 👤 Wang, Ji 👤 Lin, Yang 👤 Yuan, Jianying 👤 Xie, Zhihao 👤 Ma, Jinmin 👤 Liu, William J 👤 Wang, Dayan 👤 Xu, Wenbo 👤 Holmes, Edward C 👤 Gao, George F 👤 Wu, Guizhen 👤 Chen, Weijun 👤 Shi, Weifeng 👤 Tan, Wenjie ⏰ 2020 📚 Lancet
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Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2
👤 Matsuyama, Shutoku 👤 Nagata, Noriyo 👤 Shirato, Kazuya 👤 Kawase, Miyuki 👤 Takeda, Makoto 👤 Taguchi, Fumihiro ⏰ 2010 📚 Journal of Virology
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Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus
👤 McCray Jr., Paul B. 👤 Pewe, Lecia 👤 Wohlford-Lenane, Christine 👤 Hickey, Melissa 👤 Manzel, Lori 👤 Shi, Lei 👤 Netland, Jason 👤 Jia, Hong Peng 👤 Halabi, Carmen 👤 Sigmund, Curt D. 👤 Meyerholz, David K. 👤 Kirby, Patricia 👤 Look, Dwight C. 👤 Perlman, Stanley ⏰ 2007 📚 Journal of Virology
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A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
👤 Menachery, Vineet D. 👤 Yount, Boyd L. 👤 Debbink, Kari 👤 Agnihothram, Sudhakar 👤 Gralinski, Lisa E. 👤 Plante, Jessica A. 👤 Graham, Rachel L. 👤 Scobey, Trevor 👤 Ge, Xing Yi 👤 Donaldson, Eric F. 👤 Randell, Scott H. 👤 Lanzavecchia, Antonio 👤 Marasco, Wayne A. 👤 Shi, Zhengli Li 👤 Baric, Ralph S. ⏰ 2015 📚 Nature Medicine
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Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension.
👤 Meng, Juan 👤 Xiao, Guohui 👤 Zhang, Juanjuan 👤 He, Xing 👤 Ou, Min 👤 Bi, Jing 👤 Yang, Rongqing 👤 Di, Wencheng 👤 Wang, Zhaoqin 👤 Li, Zigang 👤 Gao, Hong 👤 Liu, Lei 👤 Zhang, Guoliang ⏰ 2020 📚 Emerg Microbes Infect
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Human coronavirus NL63 utilizes heparan sulfate proteoglycans for attachment to target cells
👤 Milewska, Aleksandra 👤 Zarebski, Miroslaw 👤 Nowak, Paulina 👤 Stozek, Karol 👤 Potempa, Jan 👤 Pyrc, Krzysztof ⏰ 2014 📚 Journal of Virology
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Retroviruses pseudotyped with the severe acute respiratory syndrome coronavirus spike protein efficiently infect cells expressing angiotensin-converting enzyme 2
👤 Moore, Michael J. 👤 Dorfman, Tatyana 👤 Li, Wenhui 👤 Wong, Swee Kee 👤 Li, Yanhan 👤 Kuhn, Jens H. 👤 Coderre, James 👤 Vasilieva, Natalya 👤 Han, Zhongchao 👤 Greenough, Thomas C. 👤 Farzan, Michael 👤 Choe, Hyeryun ⏰ 2004 📚 Journal of Virology
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Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication
👤 Mossel, Eric C. 👤 Huang, Cheng 👤 Narayanan, Krishna 👤 Makino, Shinji 👤 Tesh, Robert B. 👤 Peters, C. J. ⏰ 2005 📚 Journal of Virology
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Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission
👤 Muth, Doreen 👤 Corman, Victor Max 👤 Roth, Hanna 👤 Binger, Tabea 👤 Dijkman, Ronald 👤 Gottula, Lina Theresa 👤 Gloza-Rausch, Florian 👤 Balboni, Andrea 👤 Battilani, Mara 👤 Rihtarič, Danijela 👤 Toplak, Ivan 👤 Ameneiros, Ramón Seage 👤 Pfeifer, Alexander 👤 Thiel, Volker 👤 Drexler, Jan Felix 👤 Müller, Marcel Alexander 👤 Drosten, Christian ⏰ 2018 📚 Scientific Reports
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Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines
👤 Müller, Marcel A. 👤 Raj, V. Stalin 👤 Muth, Doreen 👤 Meyer, Benjamin 👤 Kallies, Stephan 👤 Smits, Saskia L. 👤 Wollny, Robert 👤 Bestebroer, Theo M. 👤 Specht, Sabine 👤 Suliman, Tasnim 👤 Zimmermann, Katrin 👤 Binger, Tabea 👤 Eckerle, Isabella 👤 Tschapka, Marco 👤 Zaki, Ali M. 👤 Osterhaus, Albert D.M.E. 👤 Fouchier, Ron A.M. 👤 Haagmans, Bart L. 👤 Drosten, Christian ⏰ 2012 📚 mBio
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Participation of both host and virus factors in induction of Severe Acute Respiratory Syndrome (SARS) in F344 rats infected with SARS coronavirus
👤 Nagata, Noriyo 👤 Iwata, Naoko 👤 Hasegawa, Hideki 👤 Fukushi, Shuetsu 👤 Yokoyama, Masaru 👤 Harashima, Ayako 👤 Sato, Yuko 👤 Saijo, Masayuki 👤 Morikawa, Shigeru 👤 Sata, Tetsutaro ⏰ 2007 📚 Journal of Virology
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Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2
👤 Netland, Jason 👤 Meyerholz, David K. 👤 Moore, Steven 👤 Cassell, Martin 👤 Perlman, Stanley ⏰ 2008 📚 Journal of Virology
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Potential enhancement of osteoclastogenesis by severe acute respiratory syndrome coronavirus 3a/X1 protein.
👤 Obitsu, Saemi 👤 Ahmed, Nursarat 👤 Nishitsuji, Hironori 👤 Hasegawa, Atsuhiko 👤 Nakahama, Ken ichi 👤 Morita, Ikuo 👤 Nishigaki, Kazuo 👤 Hayashi, Takaya 👤 Masuda, Takao 👤 Kannagi, Mari ⏰ 2009 📚 Archives of virology
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Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV.
👤 Ou, Xiuyuan 👤 Liu, Yan 👤 Lei, Xiaobo 👤 Li, Pei 👤 Mi, Dan 👤 Ren, Lili 👤 Guo, Li 👤 Guo, Ruixuan 👤 Chen, Ting 👤 Hu, Jiaxin 👤 Xiang, Zichun 👤 Mu, Zhixia 👤 Chen, Xing 👤 Chen, Jieyong 👤 Hu, Keping 👤 Jin, Qi 👤 Wang, Jianwei 👤 Qian, Zhaohui ⏰ 2020 📚 Nat Commun
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SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS
👤 Oudit, G. Y. 👤 Kassiri, Z. 👤 Jiang, C. 👤 Liu, P. P. 👤 Poutanen, S. M. 👤 Penninger, J. M. 👤 Butany, J. ⏰ 2009 📚 European Journal of Clinical Investigation
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Persistent replication of severe acute respiratory syndrome coronavirus in human tubular kidney cells selects for adaptive mutations in the membrane protein
👤 Pacciarini, Filippo 👤 Ghezzi, Silvia 👤 Canducci, Filippo 👤 Sims, Amy 👤 Sampaolo, Michela 👤 Ferioli, Elena 👤 Clementi, Massimo 👤 Poli, Guido 👤 Conaldi, Pier Giulio 👤 Baric, Ralph 👤 Vicenzi, Elisa ⏰ 2008 📚 Journal of Virology
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Structural Insights into Immune Recognition of the Severe Acute Respiratory Syndrome Coronavirus S Protein Receptor Binding Domain
👤 Pak, John E. 👤 Sharon, Chetna 👤 Satkunarajah, Malathy 👤 Auperin, Thierry C. 👤 Cameron, Cheryl M. 👤 Kelvin, David J. 👤 Seetharaman, Jayaraman 👤 Cochrane, Alan 👤 Plummer, Francis A. 👤 Berry, Jody D. 👤 Rini, James M. ⏰ 2009 📚 Journal of Molecular Biology
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Transmission routes of 2019-nCoV and controls in dental practice.
👤 Peng, Xian 👤 Xu, Xin 👤 Li, Yuqing 👤 Cheng, Lei 👤 Zhou, Xuedong 👤 Ren, Biao ⏰ 2020 📚 Int J Oral Sci
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Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody
👤 Prabakaran, Ponraj 👤 Gan, Jianhua 👤 Feng, Yang 👤 Zhu, Zhongyu 👤 Choudhry, Vidita 👤 Xiao, Xiaodong 👤 Ji, Xinhua 👤 Dimitrov, Dimiter S. ⏰ 2006 📚 Journal of Biological Chemistry
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Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses.
👤 Qi, Furong 👤 Qian, Shen 👤 Zhang, Shuye 👤 Zhang, Zheng ⏰ 2020 📚 Biochem Biophys Res Commun
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Innate immune response of human alveolar type II cells infected with severe acute respiratory syndrome-coronavirus
👤 Qian, Zhaohui 👤 Travanty, Emily A. 👤 Oko, Lauren 👤 Edeen, Karen 👤 Berglund, Andrew 👤 Wang, Jieru 👤 Ito, Yoko 👤 Holmes, Kathryn V. 👤 Mason, Robert J. ⏰ 2013 📚 American Journal of Respiratory Cell and Molecular Biology
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Using the spike protein feature to predict infection risk and monitor the evolutionary dynamic of coronavirus.
👤 Qiang, Xiao-Li 👤 Xu, Peng 👤 Fang, Gang 👤 Liu, Wen-Bin 👤 Kou, Zheng ⏰ 2020 📚 Infect Dis Poverty
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Predicting the angiotensin converting enzyme 2 (ACE2) utilizing capability as the receptor of SARS-CoV-2.
👤 Qiu, Ye 👤 Zhao, Yuan-Bo 👤 Wang, Qiong 👤 Li, Jin-Yan 👤 Zhou, Zhi-Jian 👤 Liao, Ce-Heng 👤 Ge, Xing-Yi ⏰ 2020 📚 Microbes Infect
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Difference in receptor usage between Severe Acute Respiratory Syndrome (SARS) coronavirus and SARS-like coronavirus of bat origin
👤 Ren, Wuze 👤 Qu, Xiuxia 👤 Li, Wendong 👤 Han, Zhenggang 👤 Yu, Meng 👤 Zhou, Peng 👤 Zhang, Shu Yi 👤 Wang, Lin Fa 👤 Deng, Hongkui 👤 Shi, Zhengli ⏰ 2008 📚 Journal of Virology
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Analysis of ACE2 in polarized epithelial cells: Surface expression and function as receptor for severe acute respiratory syndrome-associated coronavirus
👤 Ren, Xiaofeng 👤 Glende, Jörg 👤 Al-Falah, Marwan 👤 de Vries, Victor 👤 Schwegmann-Wessels, Christel 👤 Qu, Xiuxia 👤 Tan, Lei 👤 Tschernig, Thomas 👤 Deng, Hongkui 👤 Naim, Hassan Y. 👤 Herrler, Georg ⏰ 2006 📚 Journal of General Virology
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Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients.
👤 Rossi, Gian Paolo 👤 Sanga, Viola 👤 Barton, Matthias ⏰ 2020 📚 Elife
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COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?
👤 Sargiacomo, Camillo 👤 Sotgia, Federica 👤 Lisanti, Michael P ⏰ 2020 📚 Aging (Albany NY)
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Severe acute respiratory syndrome coronavirus replication is severely impaired by MG132 due to proteasome-independent inhibition of M-calpain
👤 Schneider, Martha 👤 Ackermann, Kerstin 👤 Stuart, Melissa 👤 Wex, Claudia 👤 Protzer, Ulrike 👤 Schätzl, Hermann M. 👤 Gilch, Sabine ⏰ 2012 📚 Journal of Virology
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COVID-19 And Older Adults: What We Know.
👤 Shahid, Zainab 👤 Kalayanamitra, Ricci 👤 McClafferty, Brendan 👤 Kepko, Douglas 👤 Ramgobin, Devyani 👤 Patel, Ravi 👤 Aggarwal, Chander Shekher 👤 Vunnam, Rama Rao 👤 Sahu, Nitasa 👤 Bhatt, Dhirisha 👤 Jones, Kirk 👤 Golamari, Reshma 👤 Jain, Rohit ⏰ 2020 📚 J Am Geriatr Soc
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Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium
👤 Sheahan, Timothy 👤 Rockx, Barry 👤 Donaldson, Eric 👤 Sims, Amy 👤 Pickles, Raymond 👤 Corti, Davide 👤 Baric, Ralph ⏰ 2008 📚 Journal of Virology
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Identifying epitopes responsible for neutralizing antibody and DC-SIGN binding on the spike glycoprotein of the severe acute respiratory syndrome coronavirus
👤 Shih, Yi Ping 👤 Chen, Chia Yen 👤 Liu, Shih Jen 👤 Chen, Kuan Hsuan 👤 Lee, Yuan Ming 👤 Chao, Yu Chan 👤 Chen, Yi Ming Arthur ⏰ 2006 📚 Journal of Virology
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A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry
👤 Shulla, Ana 👤 Heald-Sargent, Taylor 👤 Subramanya, Gitanjali 👤 Zhao, Jincun 👤 Perlman, Stanley 👤 Gallagher, Tom ⏰ 2011 📚 Journal of Virology
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Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: Role of ciliated cells in viral spread in the conducting airways of the lungs
👤 Sims, Amy C. 👤 Baric, Ralph S. 👤 Yount, Boyd 👤 Burkett, Susan E. 👤 Collins, Peter L. 👤 Pickles, Raymond J. ⏰ 2005 📚 Journal of Virology
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Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2
👤 Song, Wenfei 👤 Gui, Miao 👤 Wang, Xinquan 👤 Xiang, Ye ⏰ 2018 📚 PLoS Pathogens
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COVID-19, ACE2 and the Cardiovascular Consequences.
👤 South, Andrew Michael 👤 Diz, Debra 👤 Chappell, Mark C ⏰ 2020 📚 Am J Physiol Heart Circ Physiol
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Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness
👤 Sui, Jianhua 👤 Deming, Meagan 👤 Rockx, Barry 👤 Liddington, Robert C. 👤 Zhu, Quan Karen 👤 Baric, Ralph S. 👤 Marasco, Wayne A. ⏰ 2014 📚 Journal of Virology
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Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association
👤 Sui, Jianhua 👤 Li, Wenhui 👤 Murakami, Akikazu 👤 Tamin, Azaibi 👤 Matthews, Leslie J. 👤 Wong, Swee Kee 👤 Moore, Michael J. 👤 Tallarico, Aimee St Clair 👤 Olurinde, Mobolaji 👤 Choe, Hyeryun 👤 Anderson, Larry J. 👤 Bellini, William J. 👤 Farzan, Michael 👤 Marasco, Wayne A. ⏰ 2004 📚 Proceedings of the National Academy of Sciences of the United States of America
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Potential Factors Influencing Repeated SARS Outbreaks in China.
👤 Sun, Zhong 👤 Thilakavathy, Karuppiah 👤 Kumar, S Suresh 👤 He, Guozhong 👤 Liu, Shi V ⏰ 2020 📚 Int J Environ Res Public Health
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Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine.
👤 Tai, Wanbo 👤 He, Lei 👤 Zhang, Xiujuan 👤 Pu, Jing 👤 Voronin, Denis 👤 Jiang, Shibo 👤 Zhou, Yusen 👤 Du, Lanying ⏰ 2020 📚 Cell Mol Immunol
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A consensus statement on the use of angiotensin receptor blockers and angiotensin converting enzyme inhibitors in relation to COVID-19 (corona virus disease 2019).
👤 Talreja, Hari 👤 Tan, Jasmine 👤 Dawes, Matt 👤 Supershad, Sharen 👤 Rabindranath, Kannaiyan 👤 Fisher, James 👤 Valappil, Sajed 👤 van der Merwe, Veronica 👤 Wong, Lisa 👤 van der Merwe, Walter 👤 Paton, Julian ⏰ 2020 📚 N Z Med J
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Review article: gastrointestinal features in COVID-19 and the possibility of faecal transmission.
👤 Tian, Yuan 👤 Rong, Long 👤 Nian, Weidong 👤 He, Yan ⏰ 2020 📚 Aliment Pharmacol Ther
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Exploring the pathogenesis of severe acute respiratory syndrome (SARS): The tissue distribution of the coronavirus (SARS-CoV) and its putative receptor, angiotensin-converting enzyme 2 (ACE2)
👤 To, K. F. 👤 Lo, Anthony W.I. ⏰ 2004 📚 Journal of Pathology
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ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19.
👤 Touyz, Rhian M 👤 Li, Hongliang 👤 Delles, Christian ⏰ 2020 📚 Clin Sci (Lond)
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Apical entry and release of severe acute respiratory syndrome-associated coronavirus in polarized Calu-3 lung epithelial cells
👤 Tseng, Chien Te K. 👤 Tseng, Jennifer 👤 Perrone, Lucy 👤 Worthy, Melissa 👤 Popov, Vsevolod 👤 Peters, Clarence J. ⏰ 2005 📚 Journal of Virology
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Pathology of experimental SARS coronavirus infection in cats and ferrets
👤 Van Den Brand, J. M.A. 👤 L.haagmans, B. 👤 Leijten, L. 👤 Van Riel, D. 👤 E.martina, B. E. 👤 Osterhaus, A. D.M.E. 👤 Kuiken, T. ⏰ 2008 📚 Veterinary Pathology
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SARS-Like coronavirus WIV1-CoV does not replicate in Egyptian fruit bats (Rousettus aegyptiacus)
👤 van Doremalen, Neeltje 👤 Schäfer, Alexandra 👤 Menachery, Vineet D. 👤 Letko, Michael 👤 Bushmaker, Trenton 👤 Fischer, Robert J. 👤 Figueroa, Dania M. 👤 Hanley, Patrick W. 👤 Saturday, Greg 👤 Baric, Ralph S. 👤 Munster, Vincent J. ⏰ 2018 📚 Viruses
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Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
👤 Vincent, Martin J. 👤 Bergeron, Eric 👤 Benjannet, Suzanne 👤 Erickson, Bobbie R. 👤 Rollin, Pierre E. 👤 Ksiazek, Thomas G. 👤 Seidah, Nabil G. 👤 Nichol, Stuart T. ⏰ 2005 📚 Virology Journal
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Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus.
👤 Wan, Yushun 👤 Shang, Jian 👤 Graham, Rachel 👤 Baric, Ralph S 👤 Li, Fang ⏰ 2020 📚 J Virol
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SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway
👤 Wang, Hongliang 👤 Yang, Peng 👤 Liu, Kangtai 👤 Guo, Feng 👤 Zhang, Yanli 👤 Zhang, Gongyi 👤 Jiang, Chengyu ⏰ 2008 📚 Cell Research
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Expression cloning of functional receptor used by SARS coronavirus
👤 Wang, Peigang 👤 Chen, Jian 👤 Zheng, Aihua 👤 Nie, Yuchun 👤 Shi, Xuanling 👤 Wang, Wei 👤 Wang, Guangwen 👤 Luo, Min 👤 Liu, Huijun 👤 Tan, Lei 👤 Song, Xijun 👤 Wang, Zai 👤 Yin, Xiaolei 👤 Qu, Xiuxia 👤 Wang, Xiaojing 👤 Qing, Tingting 👤 Ding, Mingxiao 👤 Deng, Hongkui ⏰ 2004 📚 Biochemical and Biophysical Research Communications
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Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins
👤 Wang, Sheng Fan 👤 Tseng, Sung Pin 👤 Yen, Chia Hung 👤 Yang, Jyh Yuan 👤 Tsao, Ching Han 👤 Shen, Chun Wei 👤 Chen, Kuan Hsuan 👤 Liu, Fu Tong 👤 Liu, Wu Tse 👤 Chen, Yi Ming Arthur 👤 Huang, Jason C. ⏰ 2014 📚 Biochemical and Biophysical Research Communications
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Covid-19 and the Digestive System.
👤 Wong, Sunny H 👤 Lui, Rashid Ns 👤 Sung, Joseph Jy ⏰ 2020 📚 J Gastroenterol Hepatol
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A 193-Amino Acid Fragment of the SARS Coronavirus S Protein Efficiently Binds Angiotensin-converting Enzyme 2
👤 Wong, Swee Kee 👤 Li, Wenhui 👤 Moore, Michael J. 👤 Choe, Hyeryun 👤 Farzan, Michael ⏰ 2004 📚 Journal of Biological Chemistry
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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
👤 Wrapp, Daniel 👤 Wang, Nianshuang 👤 Corbett, Kizzmekia S 👤 Goldsmith, Jory A 👤 Hsieh, Ching-Lin 👤 Abiona, Olubukola 👤 Graham, Barney S 👤 McLellan, Jason S ⏰ 2020 📚 Science
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A virus-binding hot spot on human angiotensin-converting enzyme 2 is critical for binding of two different coronaviruses
👤 Wu, Kailang 👤 Chen, Lang 👤 Peng, Guiqing 👤 Zhou, Wenbo 👤 Pennell, Christopher A. 👤 Mansky, Louis M. 👤 Geraghty, Robert J. 👤 Li, Fang ⏰ 2011 📚 Journal of Virology
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Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor
👤 Wu, Kailang 👤 Li, Weikai 👤 Peng, Guiqing 👤 Li, Fang ⏰ 2009 📚 Proceedings of the National Academy of Sciences of the United States of America
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Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus
👤 Wu, Kailang 👤 Peng, Guiqing 👤 Wilken, Matthew 👤 Geraghty, Robert J. 👤 Li, Fang ⏰ 2012 📚 Journal of Biological Chemistry
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Angiotensin-converting enzyme 2 (ACE2) from raccoon dog can serve as an efficient receptor for the spike protein of severe acute respiratory syndrome coronavirus
👤 Xu, Lili 👤 Zhang, Yanfang 👤 Liu, Yun 👤 Chen, Zhiwei 👤 Deng, Hongkui 👤 Ma, Zhongbin 👤 Wang, Hualin 👤 Hu, Zhihong 👤 Deng, Fei ⏰ 2009 📚 Journal of General Virology
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Susceptibility of human and rat neural cell lines to infection by SARS-coronavirus
👤 Yamashita, Makiko 👤 Yamate, Masanobu 👤 Li, Gui Mei 👤 Ikuta, Kazuyoshi ⏰ 2005 📚 Biochemical and Biophysical Research Communications
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Establishment of Vero E6 cell clones persistently infected with severe acute respiratory syndrome coronavirus
👤 Yamate, Masanobu 👤 Yamashita, Makiko 👤 Goto, Toshiyuki 👤 Tsuji, Shoutaro 👤 Li, Yong Gang 👤 Warachit, Jiranan 👤 Yunoki, Mikihiro 👤 Ikuta, Kazuyoshi ⏰ 2005 📚 Microbes and Infection
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Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2.
👤 Yan, Renhong 👤 Zhang, Yuanyuan 👤 Li, Yaning 👤 Xia, Lu 👤 Guo, Yingying 👤 Zhou, Qiang ⏰ 2020 📚 Science
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Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes
👤 Yang, Jin Kui 👤 Lin, Shan Shan 👤 Ji, Xiu Juan 👤 Guo, Li Min ⏰ 2010 📚 Acta Diabetologica
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Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses
👤 Yang, Zhi Yong 👤 Werner, Heidi C. 👤 Kong, Wing Pui 👤 Leung, Kwanyee 👤 Traggiai, Elisabetta 👤 Lanzavecchia, Antonio 👤 Nabel, Gary J. ⏰ 2005 📚 Proceedings of the National Academy of Sciences of the United States of America
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Severe acute respiratory syndrome coronavirus entry into host cells: Opportunities for therapeutic intervention
👤 Yeung, Kap Sun 👤 Yamanaka, Gregory A. 👤 Meanwell, Nicholas A. ⏰ 2006 📚 Medicinal Research Reviews
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Single amino acid substitutions in the severe acute respiratory syndrome coronavirus spike glycoprotein determine viral entry and immunogenicity of a major neutralizing domain
👤 Yi, Christopher E. 👤 Ba, Lei 👤 Zhang, Linqi 👤 Ho, David D. 👤 Chen, Zhiwei ⏰ 2005 📚 Journal of Virology
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Differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human angiotensin-converting enzyme 2
👤 Yoshikawa, Naoko 👤 Yoshikawa, Tomoki 👤 Hill, Terence 👤 Huang, Cheng 👤 Watts, Douglas M. 👤 Makino, Shinji 👤 Milligan, Gregg 👤 Chan, Tehsheng 👤 Peters, Clarence J. 👤 Tseng, Chien Te K. ⏰ 2009 📚 Journal of Virology
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Identification of key amino acid residues required for horseshoe bat angiotensin-I converting enzyme 2 to function as a receptor for severe acute respiratory syndrome coronavirus
👤 Yu, Meng 👤 Tachedjian, Mary 👤 Crameri, Gary 👤 Shi, Zhengli 👤 Wang, Lin Fa ⏰ 2010 📚 Journal of General Virology
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Computational simulation of interactions between SARS coronavirus spike mutants and host species-specific receptors
👤 Zhang, Yuan 👤 Zheng, Nan 👤 Nan, Peng 👤 Cao, Ying 👤 Hasegawa, Masami 👤 Zhong, Yang ⏰ 2007 📚 Computational Biology and Chemistry
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Inhibition of endoplasmic reticulum-resident glucosidases impairs severe acute respiratory syndrome coronavirus and human coronavirus NL63 spike protein-mediated entry by altering the glycan processing of angiotensin I-converting enzyme 2
👤 Zhao, Xuesen 👤 Guo, Fang 👤 Comunale, Mary Ann 👤 Mehta, Anand 👤 Sehgal, Mohit 👤 Jain, Pooja 👤 Cuconati, Andrea 👤 Lin, Hanxin 👤 Block, Timothy M. 👤 Chang, Jinhong 👤 Guo, Ju Tao ⏰ 2015 📚 Antimicrobial Agents and Chemotherapy
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Screening and identification of severe acute respiratory syndrome-associated coronavirus-specific CTL epitopes
👤 Zhou, Minghai 👤 Xu, Dongping 👤 Li, Xiaojuan 👤 Li, Hongtao 👤 Shan, Ming 👤 Tang, Jiaren 👤 Wang, Min 👤 Wang, Fu Sheng 👤 Zhu, Xiaodong 👤 Tao, Hua 👤 He, Wei 👤 Tien, Po 👤 Gao, George F. ⏰ 2006 📚 Journal of Immunology
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A pneumonia outbreak associated with a new coronavirus of probable bat origin.
👤 Zhou, Peng 👤 Yang, Xing-Lou 👤 Wang, Xian-Guang 👤 Hu, Ben 👤 Zhang, Lei 👤 Zhang, Wei 👤 Si, Hao-Rui 👤 Zhu, Yan 👤 Li, Bei 👤 Huang, Chao-Lin 👤 Chen, Hui-Dong 👤 Chen, Jing 👤 Luo, Yun 👤 Guo, Hua 👤 Jiang, Ren-Di 👤 Liu, Mei-Qin 👤 Chen, Ying 👤 Shen, Xu-Rui 👤 Wang, Xi 👤 Zheng, Xiao-Shuang 👤 Zhao, Kai 👤 Chen, Quan-Jiao 👤 Deng, Fei 👤 Liu, Lin-Lin 👤 Yan, Bing 👤 Zhan, Fa-Xian 👤 Wang, Yan-Yi 👤 Xiao, Geng-Fu 👤 Shi, Zheng-Li ⏰ 2020 📚 Nature
- Possible causes for decreased susceptibility of children to coronavirus.
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Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection.
👤 Zou, Xin 👤 Chen, Ke 👤 Zou, Jiawei 👤 Han, Peiyi 👤 Hao, Jie 👤 Han, Zeguang ⏰ 2020 📚 Front Med