📄 Comment on "Organ-protective Effect of Angiotensin-converting Enzyme 2 and its Effect on the Prognosis of COVID-19".

We read with great interest the article by Cheng H et al. The authors mentioned that angiotensin-converting enzyme 2 (ACE2) is protective against novel coronavirus disease 2019 (COVID-19). We would like to explain how cytosolic pH increases the COVID-19 infection by affecting the ACE2. In addition, we would like to mention that amiloride, which increases the cytosolic pH, can be used in the COVID-19 treatment. This article is protected by copyright.

keywords 🔗 ACE2 (181) 🔗 ACEI (5) 🔗 ARBs (7) 🔗 ARDS (199) 🔗 Amiloride () 🔗 COVID-19 (1240) 🔗 SARS-CoV-2 (551) 🔗 acute respiratory distress syndrome (106) 🔗 angiotensin II receptor blockers (2) 🔗 angiotensin-converting enzyme 2 (117) 🔗 angiotensin-converting enzyme inhibitors (3) 🔗 coronavirus disease 2019 (384) 🔗 cytosolic pH (1) 🔗 converting enzyme (162) 🔗 novel coronavirus (684) 🔗 angiotensin-converting enzyme (112)

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