🔗 Angiotensin-converting enzyme

Articles (112)

• Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host-Virus Interaction, and Proposed Neurotropic Mechanisms.

  👤 Baig, Abdul Mannan 👤 Khaleeq, Areeba 👤 Ali, Usman 👤 Syeda, Hira ⏰ 2020 📚 ACS Chem Neurosci

• Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?

  👤 Batlle, Daniel 👤 Wysocki, Jan 👤 Satchell, Karla ⏰ 2020 📚 Clin Sci (Lond)

• Conformational reorganization of the SARS coronavirus spike following receptor binding: Implications for membrane fusion

  👤 Beniac, Daniel R. 👤 de Varennes, Shauna L. 👤 Andonov, Anton 👤 He, Runtao 👤 Booth, Tim F. ⏰ 2007 📚 PLoS ONE

• Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease

  👤 Bertram, Stephanie 👤 Glowacka, Ilona 👤 Müller, Marcel A. 👤 Lavender, Hayley 👤 Gnirss, Kerstin 👤 Nehlmeier, Inga 👤 Niemeyer, Daniela 👤 He, Yuxian 👤 Simmons, Graham 👤 Drosten, Christian 👤 Soilleux, Elizabeth J. 👤 Jahn, Olaf 👤 Steffen, Imke 👤 Pöhlmann, Stefan ⏰ 2011 📚 Journal of Virology

• Membrane ectopeptidases targeted by human coronaviruses

  👤 Bosch, Berend Jan 👤 Smits, Saskia L. 👤 Haagmans, Bart L. ⏰ 2014 📚 Current Opinion in Virology

• Smoking Upregulates Angiotensin-Converting Enzyme-2 Receptor: A Potential Adhesion Site for Novel Coronavirus SARS-CoV-2 (Covid-19).

  👤 Brake, Samuel James 👤 Barnsley, Kathryn 👤 Lu, Wenying 👤 McAlinden, Kielan Darcy 👤 Eapen, Mathew Suji 👤 Sohal, Sukhwinder Singh ⏰ 2020 📚 J Clin Med

• Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility.

  👤 Chan, Jasper Fuk-Woo 👤 Zhang, Anna Jinxia 👤 Yuan, Shuofeng 👤 Poon, Vincent Kwok-Man 👤 Chan, Chris Chung-Sing 👤 Lee, Andrew Chak-Yiu 👤 Chan, Wan-Mui 👤 Fan, Zhimeng 👤 Tsoi, Hoi-Wah 👤 Wen, Lei 👤 Liang, Ronghui 👤 Cao, Jianli 👤 Chen, Yanxia 👤 Tang, Kaiming 👤 Luo, Cuiting 👤 Cai, Jian-Piao 👤 Kok, Kin-Hang 👤 Chu, Hin 👤 Chan, Kwok-Hung 👤 Sridhar, Siddharth 👤 Chen, Zhiwei 👤 Chen, Honglin 👤 To, Kelvin Kai-Wang 👤 Yuen, Kwok-Yung ⏰ 2020 📚 Clin Infect Dis

• Persistent infection of SARS coronavirus in colonic cells in vitro

  👤 Chan, Paul K.S. 👤 To, Ka Fai 👤 Lo, Anthony W.I. 👤 Cheung, Jo L.K. 👤 Chu, Ida 👤 Au, Florence W.L. 👤 Tong, Joanna H.M. 👤 Tam, John S. 👤 Sung, Joseph J.Y. 👤 Ng, Ho Keung ⏰ 2004 📚 Journal of Medical Virology

• Induction of IL-8 release in lung cells via activator protein-1 by recombinant baculovirus displaying severe acute respiratory syndrome-coronavirus spike proteins: Identification of two functional regions

  👤 Chang, Ya Jen 👤 Liu, Catherine Y.Y. 👤 Chiang, Bor Luen 👤 Chao, Yu Chan 👤 Chen, Ching Chow ⏰ 2004 📚 Journal of Immunology

• A novel subset of putative stem/progenitor CD34+ Oct-4 + cells is the major target for SARS coronavirus in human lung

  👤 Chen, Yongxiong 👤 Chan, Vera Sau Fong 👤 Zheng, Bojian 👤 Chan, Kelvin Yuen Kwong 👤 Xu, Xiaoning 👤 To, Leo Yuk Fai 👤 Huang, Fang Ping 👤 Khoo, Ui Soon 👤 Lin, Chen Lung Steve ⏰ 2007 📚 Journal of Experimental Medicine

• Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region

  👤 Chen, Zhiwei 👤 Zhang, Linqi 👤 Qin, Chuan 👤 Ba, Lei 👤 Yi, Christopher E. 👤 Zhang, Fengwen 👤 Wei, Qiang 👤 He, Tian 👤 Yu, Wenjie 👤 Yu, Jian 👤 Gao, Hong 👤 Tu, Xinming 👤 Gettie, Agegnehu 👤 Farzan, Michael 👤 Yuen, Kwok Yung 👤 Ho, David D. ⏰ 2005 📚 Journal of Virology

• Organ-protective effect of angiotensin-converting enzyme 2 and its effect on the prognosis of COVID-19.

  👤 Cheng, Hao 👤 Wang, Yan 👤 Wang, Gui-Qiang ⏰ 2020 📚 J Med Virol

• The use of hepatitis C virus NS3/4A and secreted alkaline phosphatase to quantitate cell-cell membrane fusion mediated by severe acute respiratory syndrome coronavirus S protein and the receptor angiotensin-converting enzyme 2

  👤 Chou, Chih Fong 👤 Shen, Shuo 👤 Mahadevappa, Geetha 👤 Lim, Seng Gee 👤 Hong, Wanjin 👤 Tan, Yee Joo ⏰ 2007 📚 Analytical Biochemistry

• Comment on "Organ-protective Effect of Angiotensin-converting Enzyme 2 and its Effect on the Prognosis of COVID-19".

  👤 Cure, Erkan 👤 Cumhur Cure, Medine ⏰ 2020 📚 J Med Virol

• Renin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers.

  👤 Danser, A H Jan 👤 Epstein, Murray 👤 Batlle, Daniel ⏰ 2020 📚 Hypertension

• Interferon-γ and interleukin-4 downregulate expression of the SARS coronavirus receptor ACE2 in Vero E6 cells

  👤 de Lang, Anna 👤 Osterhaus, Albert D.M.E. 👤 Haagmans, Bart L. ⏰ 2006 📚 Virology

• Evidence for ACE2-utilizing coronaviruses (covs) related to severe acute respiratory syndrome cov in bats

  👤 Demogines, Ann 👤 Farzan, Michael 👤 Sawyer, Sara L. ⏰ 2012 📚 Journal of Virology

• Hypothesis: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19.

  👤 Diaz, James H ⏰ 2020 📚 J Travel Med

• Replication-dependent downregulation of cellular angiotensin-converting enzyme 2 protein expression by human coronavirus NL63

  👤 Dijkman, Ronald 👤 Jebbink, Maarten F. 👤 Deijs, Martin 👤 Milewska, Aleksandra 👤 Pyrc, Krzysztof 👤 Buelow, Elena 👤 van der Bijl, Anna 👤 van der Hoek, Lia ⏰ 2012 📚 Journal of General Virology

• Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus (2019-nCoV) related coronavirus model.

  👤 Fan, Hua-Hao 👤 Wang, Li-Qin 👤 Liu, Wen-Li 👤 An, Xiao-Ping 👤 Liu, Zhen-Dong 👤 He, Xiao-Qi 👤 Song, Li-Hua 👤 Tong, Yi-Gang ⏰ 2020 📚 Chin Med J (Engl)

• Reconstitution of the receptor-binding motif of the SARS coronavirus

  👤 Freund, Natalia T. 👤 Roitburd-Berman, Anna 👤 Sui, Jianhua 👤 Marasco, Wayne A. 👤 Gershoni, Jonathan M. ⏰ 2015 📚 Protein Engineering, Design and Selection

• Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease

  👤 Frieman, Matthew 👤 Yount, Boyd 👤 Agnihothram, Sudhakar 👤 Page, Carly 👤 Donaldson, Eric 👤 Roberts, Anjeanette 👤 Vogel, Leatrice 👤 Woodruff, Becky 👤 Scorpio, Diana 👤 Subbarao, Kanta 👤 Baric, Ralph S. ⏰ 2012 📚 Journal of Virology

• Vesicular stomatitis virus pseudotyped with severe acute respiratory syndrome coronavirus spike protein

  👤 Fukushi, Shuetsu 👤 Mizutani, Tetsuya 👤 Saijo, Masayuki 👤 Matsuyama, Shutoku 👤 Miyajima, Naoko 👤 Taguchi, Fumihiro 👤 Itamura, Shigeyuki 👤 Kurane, Ichiro 👤 Morikawa, Shigeru ⏰ 2005 📚 Journal of General Virology

• Amino acid substitutions in the S2 region enhance severe acute respiratory syndrome coronavirus infectivity in rat angiotensin-converting enzyme 2-expressing cells

  👤 Fukushi, Shuetsu 👤 Mizutani, Tetsuya 👤 Sakai, Kouji 👤 Saijo, Masayuki 👤 Taguchi, Fumihiro 👤 Yokoyama, Masaru 👤 Kurane, Ichiro 👤 Morikawa, Shigeru ⏰ 2007 📚 Journal of Virology

• Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2

  👤 Glende, Joerg 👤 Schwegmann-Wessels, Christel 👤 Al-Falah, Marwan 👤 Pfefferle, Susanne 👤 Qu, Xiuxia 👤 Deng, Hongkui 👤 Drosten, Christian 👤 Naim, Hassan Y. 👤 Herrler, Georg ⏰ 2008 📚 Virology

• Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63

  👤 Glowacka, Ilona 👤 Bertram, Stephanie 👤 Herzog, Petra 👤 Pfefferle, Susanne 👤 Steffen, Imke 👤 Muench, Marcus O. 👤 Simmons, Graham 👤 Hofmann, Heike 👤 Kuri, Thomas 👤 Weber, Friedemann 👤 Eichler, Jutta 👤 Drosten, Christian 👤 Pöhlmann, Stefan ⏰ 2010 📚 Journal of Virology

• Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19).

  👤 Guo, Tao 👤 Fan, Yongzhen 👤 Chen, Ming 👤 Wu, Xiaoyan 👤 Zhang, Lin 👤 He, Tao 👤 Wang, Hairong 👤 Wan, Jing 👤 Wang, Xinghuan 👤 Lu, Zhibing ⏰ 2020 📚 JAMA Cardiol

• The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status.

  👤 Guo, Yan-Rong 👤 Cao, Qing-Dong 👤 Hong, Zhong-Si 👤 Tan, Yuan-Yang 👤 Chen, Shou-Deng 👤 Jin, Hong-Jun 👤 Tan, Kai-Sen 👤 Wang, De-Yun 👤 Yan, Yan ⏰ 2020 📚 Mil Med Res

• Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics.

  👤 Gurwitz, David ⏰ 2020 📚 Drug Dev Res

• Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis

  👤 Hamming, I. 👤 Timens, W. 👤 Bulthuis, M. L.C. 👤 Lely, A. T. 👤 Navis, G. J. 👤 van Goor, H. ⏰ 2004 📚 Journal of Pathology

• Specific asparagine-linked glycosylation sites are critical for DC-SIGN- and L-SIGN-mediated severe acute respiratory syndrome coronavirus entry

  👤 Han, Dong P. 👤 Lohani, Motashim 👤 Cho, Michael W. ⏰ 2007 📚 Journal of Virology

• Identification of diverse bat alphacoronaviruses and betacoronaviruses in china provides new insights into the evolution and origin of coronavirus-related diseases

  👤 Han, Yelin 👤 Du, Jiang 👤 Su, Haoxiang 👤 Zhang, Junpeng 👤 Zhu, Guangjian 👤 Zhang, Shuyi 👤 Wu, Zhiqiang 👤 Jin, Qi ⏰ 2019 📚 Frontiers in Microbiology

• Is There an Association Between COVID-19 Mortality and the Renin-Angiotensin System-a Call for Epidemiologic Investigations.

  👤 Hanff, Thomas C 👤 Harhay, Michael O 👤 Brown, Tyler S 👤 Cohen, Jordana B 👤 Mohareb, Amir M ⏰ 2020 📚 Clin Infect Dis

• A single amino acid substitution (R441A) in the receptor-binding domain of SARS coronavirus spike protein disrupts the antigenic structure and binding activity

  👤 He, Yuxian 👤 Li, Jingjing 👤 Jiang, Shibo ⏰ 2006 📚 Biochemical and Biophysical Research Communications

• Identification of a critical neutralization determinant of severe acute respiratory syndrome (SARS)-associated coronavirus: Importance for designing SARS vaccines

  👤 He, Yuxian 👤 Zhu, Qingyu 👤 Liu, Shuwen 👤 Zhou, Yusen 👤 Yang, Baoan 👤 Li, Jiaming 👤 Jiang, Shibo ⏰ 2005 📚 Virology

• TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein

  👤 Heurich, Adeline 👤 Hofmann-Winkler, Heike 👤 Gierer, Stefanie 👤 Liepold, Thomas 👤 Jahn, Olaf 👤 Pöhlmann, Stefan ⏰ 2014 📚 Journal of Virology

• Colonization of severe acute respiratory syndrome-associated coronavirus among health-care workers screened by nasopharyngeal swab

  👤 Ho, Hsin Tsung 👤 Chang, Mau Sun 👤 Wei, Tsai Yin 👤 Hsieh, Wen Shyang 👤 Hung, Chia Chien 👤 Yang, Huei Mei 👤 Lu, Yen Ta ⏰ 2006 📚 Chest

• Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction

  👤 Ho, Tin Yun 👤 Wu, Shih Lu 👤 Chen, Jaw Chyun 👤 Li, Chia Cheng 👤 Hsiang, Chien Yun ⏰ 2007 📚 Antiviral Research

• Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry

  👤 Hofmann, Heike 👤 Pyrc, Krzysztof 👤 Van Der Hoek, Lia 👤 Geier, Martina 👤 Berkhout, Ben 👤 Pöhlmann, Stefan ⏰ 2005 📚 Proceedings of the National Academy of Sciences of the United States of America

• Cellular entry of the SARS coronavirus

  👤 Hofmann, Heike 👤 Pöhlmann, Stefan ⏰ 2004 📚 Trends in Microbiology

• Screening and identification of linear B-cell epitopes and entry-blocking peptide of severe acute respiratory syndrome (SARS)-associated coronavirus using synthetic overlapping peptide library

  👤 Hu, Hongbo 👤 Li, Li 👤 Kao, Richard Y. 👤 Kou, Binbin 👤 Wang, Zhanguo 👤 Zhang, Liang 👤 Zhang, Huiyuan 👤 Hao, Zhiyong 👤 Tsui, Wayne H. 👤 Ni, Anping 👤 Cui, Lianxian 👤 Fan, Baoxing 👤 Guo, Feng 👤 Rao, Shuan 👤 Jiang, Chengyu 👤 Li, Qian 👤 Sun, Manji 👤 He, Wei 👤 Liu, Gang ⏰ 2005 📚 Journal of Combinatorial Chemistry

• Evolution of genomes, host shifts and the geographic spread of SARS-CoV and related coronaviruses

  👤 Janies, Daniel 👤 Habib, Farhat 👤 Alexandrov, Boyan 👤 Hill, Andrew 👤 Pol, Diego ⏰ 2008 📚 Cladistics

• A Comprehensive Literature Review on the Clinical Presentation, and Management of the Pandemic Coronavirus Disease 2019 (COVID-19).

  👤 Kakodkar, Pramath 👤 Kaka, Nagham 👤 Baig, M N ⏰ 2020 📚 Cureus

• COVID-19 (Novel Coronavirus 2019) - recent trends.

  👤 Kannan, S 👤 Shaik Syed Ali, P 👤 Sheeza, A 👤 Hemalatha, K ⏰ 2020 📚 Eur Rev Med Pharmacol Sci

• Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics

  👤 Kao, Richard Y. 👤 Tsui, Wayne H.W. 👤 Lee, Terri S.W. 👤 Tanner, Julian A. 👤 Watt, Rory M. 👤 Huang, Jian Dong 👤 Hu, Lihong 👤 Chen, Guanhua 👤 Chen, Zhiwei 👤 Zhang, Linqi 👤 He, Tian 👤 Chan, Kwok Hung 👤 Tse, Herman 👤 To, Amanda P.C. 👤 Ng, Louisa W.Y. 👤 Wong, Bonnie C.W. 👤 Tsoi, Hoi Wah 👤 Yang, Dan 👤 Ho, David D. 👤 Yuen, Kwok Yung ⏰ 2004 📚 Chemistry and Biology

• Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry

  👤 Kawase, Miyuki 👤 Shirato, Kazuya 👤 van der Hoek, Lia 👤 Taguchi, Fumihiro 👤 Matsuyama, Shutoku ⏰ 2012 📚 Journal of Virology

• Functional analysis of the receptor binding domain of SARS coronavirus S1 region and its monoclonal antibody

  👤 Kim, Hyun 👤 Hong, Yeongjin 👤 Shibayama, Keigo 👤 Suzuki, Yasuhiko 👤 Wakamiya, Nobutaka 👤 Kim, Youn Uck ⏰ 2014 📚 Genes and Genomics

• Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

  👤 Kirchdoerfer, Robert N. 👤 Wang, Nianshuang 👤 Pallesen, Jesper 👤 Wrapp, Daniel 👤 Turner, Hannah L. 👤 Cottrell, Christopher A. 👤 Corbett, Kizzmekia S. 👤 Graham, Barney S. 👤 McLellan, Jason S. 👤 Ward, Andrew B. ⏰ 2018 📚 Scientific Reports

• Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China.

  👤 Kruse, Robert L ⏰ 2020 📚 F1000Res

• A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury

  👤 Kuba, Keiji 👤 Imai, Yumiko 👤 Rao, Shuan 👤 Gao, Hong 👤 Guo, Feng 👤 Guan, Bin 👤 Huan, Yi 👤 Yang, Peng 👤 Zhang, Yanli 👤 Deng, Wei 👤 Bao, Linlin 👤 Zhang, Binlin 👤 Liu, Guang 👤 Wang, Zhong 👤 Chappell, Mark 👤 Liu, Yanxin 👤 Zheng, Dexian 👤 Leibbrandt, Andreas 👤 Wada, Teiji 👤 Slutsky, Arthur S. 👤 Liu, Depei 👤 Qin, Chuan 👤 Jiang, Chengyu 👤 Penninger, Josef M. ⏰ 2005 📚 Nature Medicine

• Development of human single-chain antibodies against SARS-associated coronavirus

  👤 Leung, K. M. 👤 Feng, D. X. 👤 Lou, Jianlong 👤 Zhou, Yu 👤 Fung, K. P. 👤 Waye, Mary M.Y. 👤 Tsui, Stephen K.W. 👤 Chan, Paul K.S. 👤 Marks, James D. 👤 Pang, S. F. 👤 Kan, Y. W. ⏰ 2008 📚 Intervirology

• Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections

  👤 Li, Fang ⏰ 2008 📚 Journal of Virology

• Receptor recognition and cross-species infections of SARS coronavirus

  👤 Li, Fang ⏰ 2013 📚 Antiviral Research

• Structural biology: Structure of SARS coronavirus spike receptor-binding domain complexed with receptor

  👤 Li, Fang 👤 Li, Wenhui 👤 Farzan, Michael 👤 Harrison, Stephen C. ⏰ 2005 📚 Science

• Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2

  👤 Li, Wenhui 👤 Greenough, Thomas C. 👤 Moore, Michael J. 👤 Vasilieva, Natalya 👤 Somasundaran, Mohan 👤 Sullivan, John L. 👤 Farzan, Michael 👤 Choe, Hyeryun ⏰ 2004 📚 Journal of Virology

• Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

  👤 Li, Wenhui 👤 Moore, Michael J. 👤 Vasllieva, Natalya 👤 Sui, Jianhua 👤 Wong, Swee Kee 👤 Berne, Michael A. 👤 Somasundaran, Mohan 👤 Sullivan, John L. 👤 Luzuriaga, Katherine 👤 Greeneugh, Thomas C. 👤 Choe, Hyeryun 👤 Farzan, Michael ⏰ 2003 📚 Nature

• The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2

  👤 Li, Wenhui 👤 Sui, Jianhua 👤 Huang, I. Chueh 👤 Kuhn, Jens H. 👤 Radoshitzky, Sheli R. 👤 Marasco, Wayne A. 👤 Choe, Hyeryun 👤 Farzan, Michael ⏰ 2007 📚 Virology

• Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2

  👤 Li, Wenhui 👤 Zhang, Chengsheng 👤 Sui, Jianhua 👤 Kuhn, Jens H. 👤 Moore, Michael J. 👤 Luo, Shiwen 👤 Wong, Swee Kee 👤 Huang, I. Chueh 👤 Xu, Keming 👤 Vasilieva, Natalya 👤 Murakami, Akikazu 👤 He, Yaqing 👤 Marasco, Wayne A. 👤 Guan, Yi 👤 Choe, Hyeryun 👤 Farzan, Michael ⏰ 2005 📚 EMBO Journal

• Identification of residues in the receptor-binding domain (RBD) of the spike protein of human coronavirus NL63 that are critical for the RBD-ACE2 receptor interaction

  👤 Lin, Han Xin 👤 Feng, Yan 👤 Wong, Gillian 👤 Wang, Liping 👤 Li, Bei 👤 Zhao, Xuesen 👤 Li, Yan 👤 Smaill, Fiona 👤 Zhang, Chengsheng ⏰ 2008 📚 Journal of General Virology

• Identification of pulmonary Oct-4+ stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro

  👤 Ling, Thai Yen 👤 Kuo, Ming Der 👤 Li, Chung Leung 👤 Yu, Alice L. 👤 Huang, Yen Hua 👤 Wu, Tsai Jung 👤 Lin, You Chin 👤 Chen, Shu Hwa 👤 Yu, John ⏰ 2006 📚 Proceedings of the National Academy of Sciences of the United States of America

• Natural mutations in the receptor binding domain of spike glycoprotein determine the reactivity of cross-neutralization between palm civet coronavirus and severe acute respiratory syndrome coronavirus

  👤 Liu, Li 👤 Fang, Qing 👤 Deng, Fei 👤 Wang, Hanzhong 👤 Yi, Christopher E. 👤 Ba, Lei 👤 Yu, Wenjie 👤 Lin, Richard D. 👤 Li, Taisheng 👤 Hu, Zhihong 👤 Ho, David D. 👤 Zhang, Linqi 👤 Chen, Zhiwei ⏰ 2007 📚 Journal of Virology

• Epithelial cells lining salivary gland ducts are early target cells of severe acute respiratory syndrome coronavirus infection in the upper respiratory tracts of rhesus macaques

  👤 Liu, Li 👤 Wei, Qiang 👤 Alvarez, Xavier 👤 Wang, Haibo 👤 Du, Yanhua 👤 Zhu, Hua 👤 Jiang, Hong 👤 Zhou, Jingying 👤 Lam, Pokman 👤 Zhang, Linqi 👤 Lackner, Andrew 👤 Qin, Chuan 👤 Chen, Zhiwei ⏰ 2011 📚 Journal of Virology

• Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2.

  👤 Liu, Zhixin 👤 Xiao, Xiao 👤 Wei, Xiuli 👤 Li, Jian 👤 Yang, Jing 👤 Tan, Huabing 👤 Zhu, Jianyong 👤 Zhang, Qiwei 👤 Wu, Jianguo 👤 Liu, Long ⏰ 2020 📚 J Med Virol

• Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.

  👤 Lu, Roujian 👤 Zhao, Xiang 👤 Li, Juan 👤 Niu, Peihua 👤 Yang, Bo 👤 Wu, Honglong 👤 Wang, Wenling 👤 Song, Hao 👤 Huang, Baoying 👤 Zhu, Na 👤 Bi, Yuhai 👤 Ma, Xuejun 👤 Zhan, Faxian 👤 Wang, Liang 👤 Hu, Tao 👤 Zhou, Hong 👤 Hu, Zhenhong 👤 Zhou, Weimin 👤 Zhao, Li 👤 Chen, Jing 👤 Meng, Yao 👤 Wang, Ji 👤 Lin, Yang 👤 Yuan, Jianying 👤 Xie, Zhihao 👤 Ma, Jinmin 👤 Liu, William J 👤 Wang, Dayan 👤 Xu, Wenbo 👤 Holmes, Edward C 👤 Gao, George F 👤 Wu, Guizhen 👤 Chen, Weijun 👤 Shi, Weifeng 👤 Tan, Wenjie ⏰ 2020 📚 Lancet

• Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2

  👤 Matsuyama, Shutoku 👤 Nagata, Noriyo 👤 Shirato, Kazuya 👤 Kawase, Miyuki 👤 Takeda, Makoto 👤 Taguchi, Fumihiro ⏰ 2010 📚 Journal of Virology

• Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus

  👤 McCray Jr., Paul B. 👤 Pewe, Lecia 👤 Wohlford-Lenane, Christine 👤 Hickey, Melissa 👤 Manzel, Lori 👤 Shi, Lei 👤 Netland, Jason 👤 Jia, Hong Peng 👤 Halabi, Carmen 👤 Sigmund, Curt D. 👤 Meyerholz, David K. 👤 Kirby, Patricia 👤 Look, Dwight C. 👤 Perlman, Stanley ⏰ 2007 📚 Journal of Virology

• Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension.

  👤 Meng, Juan 👤 Xiao, Guohui 👤 Zhang, Juanjuan 👤 He, Xing 👤 Ou, Min 👤 Bi, Jing 👤 Yang, Rongqing 👤 Di, Wencheng 👤 Wang, Zhaoqin 👤 Li, Zigang 👤 Gao, Hong 👤 Liu, Lei 👤 Zhang, Guoliang ⏰ 2020 📚 Emerg Microbes Infect

• Human coronavirus NL63 utilizes heparan sulfate proteoglycans for attachment to target cells

  👤 Milewska, Aleksandra 👤 Zarebski, Miroslaw 👤 Nowak, Paulina 👤 Stozek, Karol 👤 Potempa, Jan 👤 Pyrc, Krzysztof ⏰ 2014 📚 Journal of Virology

• Retroviruses pseudotyped with the severe acute respiratory syndrome coronavirus spike protein efficiently infect cells expressing angiotensin-converting enzyme 2

  👤 Moore, Michael J. 👤 Dorfman, Tatyana 👤 Li, Wenhui 👤 Wong, Swee Kee 👤 Li, Yanhan 👤 Kuhn, Jens H. 👤 Coderre, James 👤 Vasilieva, Natalya 👤 Han, Zhongchao 👤 Greenough, Thomas C. 👤 Farzan, Michael 👤 Choe, Hyeryun ⏰ 2004 📚 Journal of Virology

• Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication

  👤 Mossel, Eric C. 👤 Huang, Cheng 👤 Narayanan, Krishna 👤 Makino, Shinji 👤 Tesh, Robert B. 👤 Peters, C. J. ⏰ 2005 📚 Journal of Virology

• Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission

  👤 Muth, Doreen 👤 Corman, Victor Max 👤 Roth, Hanna 👤 Binger, Tabea 👤 Dijkman, Ronald 👤 Gottula, Lina Theresa 👤 Gloza-Rausch, Florian 👤 Balboni, Andrea 👤 Battilani, Mara 👤 Rihtarič, Danijela 👤 Toplak, Ivan 👤 Ameneiros, Ramón Seage 👤 Pfeifer, Alexander 👤 Thiel, Volker 👤 Drexler, Jan Felix 👤 Müller, Marcel Alexander 👤 Drosten, Christian ⏰ 2018 📚 Scientific Reports

• Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines

  👤 Müller, Marcel A. 👤 Raj, V. Stalin 👤 Muth, Doreen 👤 Meyer, Benjamin 👤 Kallies, Stephan 👤 Smits, Saskia L. 👤 Wollny, Robert 👤 Bestebroer, Theo M. 👤 Specht, Sabine 👤 Suliman, Tasnim 👤 Zimmermann, Katrin 👤 Binger, Tabea 👤 Eckerle, Isabella 👤 Tschapka, Marco 👤 Zaki, Ali M. 👤 Osterhaus, Albert D.M.E. 👤 Fouchier, Ron A.M. 👤 Haagmans, Bart L. 👤 Drosten, Christian ⏰ 2012 📚 mBio

• Participation of both host and virus factors in induction of Severe Acute Respiratory Syndrome (SARS) in F344 rats infected with SARS coronavirus

  👤 Nagata, Noriyo 👤 Iwata, Naoko 👤 Hasegawa, Hideki 👤 Fukushi, Shuetsu 👤 Yokoyama, Masaru 👤 Harashima, Ayako 👤 Sato, Yuko 👤 Saijo, Masayuki 👤 Morikawa, Shigeru 👤 Sata, Tetsutaro ⏰ 2007 📚 Journal of Virology

• Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2

  👤 Netland, Jason 👤 Meyerholz, David K. 👤 Moore, Steven 👤 Cassell, Martin 👤 Perlman, Stanley ⏰ 2008 📚 Journal of Virology

• Persistent replication of severe acute respiratory syndrome coronavirus in human tubular kidney cells selects for adaptive mutations in the membrane protein

  👤 Pacciarini, Filippo 👤 Ghezzi, Silvia 👤 Canducci, Filippo 👤 Sims, Amy 👤 Sampaolo, Michela 👤 Ferioli, Elena 👤 Clementi, Massimo 👤 Poli, Guido 👤 Conaldi, Pier Giulio 👤 Baric, Ralph 👤 Vicenzi, Elisa ⏰ 2008 📚 Journal of Virology

• Structural Insights into Immune Recognition of the Severe Acute Respiratory Syndrome Coronavirus S Protein Receptor Binding Domain

  👤 Pak, John E. 👤 Sharon, Chetna 👤 Satkunarajah, Malathy 👤 Auperin, Thierry C. 👤 Cameron, Cheryl M. 👤 Kelvin, David J. 👤 Seetharaman, Jayaraman 👤 Cochrane, Alan 👤 Plummer, Francis A. 👤 Berry, Jody D. 👤 Rini, James M. ⏰ 2009 📚 Journal of Molecular Biology

• Transmission routes of 2019-nCoV and controls in dental practice.

  👤 Peng, Xian 👤 Xu, Xin 👤 Li, Yuqing 👤 Cheng, Lei 👤 Zhou, Xuedong 👤 Ren, Biao ⏰ 2020 📚 Int J Oral Sci

• Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody

  👤 Prabakaran, Ponraj 👤 Gan, Jianhua 👤 Feng, Yang 👤 Zhu, Zhongyu 👤 Choudhry, Vidita 👤 Xiao, Xiaodong 👤 Ji, Xinhua 👤 Dimitrov, Dimiter S. ⏰ 2006 📚 Journal of Biological Chemistry

• Innate immune response of human alveolar type II cells infected with severe acute respiratory syndrome-coronavirus

  👤 Qian, Zhaohui 👤 Travanty, Emily A. 👤 Oko, Lauren 👤 Edeen, Karen 👤 Berglund, Andrew 👤 Wang, Jieru 👤 Ito, Yoko 👤 Holmes, Kathryn V. 👤 Mason, Robert J. ⏰ 2013 📚 American Journal of Respiratory Cell and Molecular Biology

• Difference in receptor usage between Severe Acute Respiratory Syndrome (SARS) coronavirus and SARS-like coronavirus of bat origin

  👤 Ren, Wuze 👤 Qu, Xiuxia 👤 Li, Wendong 👤 Han, Zhenggang 👤 Yu, Meng 👤 Zhou, Peng 👤 Zhang, Shu Yi 👤 Wang, Lin Fa 👤 Deng, Hongkui 👤 Shi, Zhengli ⏰ 2008 📚 Journal of Virology

• Analysis of ACE2 in polarized epithelial cells: Surface expression and function as receptor for severe acute respiratory syndrome-associated coronavirus

  👤 Ren, Xiaofeng 👤 Glende, Jörg 👤 Al-Falah, Marwan 👤 de Vries, Victor 👤 Schwegmann-Wessels, Christel 👤 Qu, Xiuxia 👤 Tan, Lei 👤 Tschernig, Thomas 👤 Deng, Hongkui 👤 Naim, Hassan Y. 👤 Herrler, Georg ⏰ 2006 📚 Journal of General Virology

• COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?

  👤 Sargiacomo, Camillo 👤 Sotgia, Federica 👤 Lisanti, Michael P ⏰ 2020 📚 Aging (Albany NY)

• Severe acute respiratory syndrome coronavirus replication is severely impaired by MG132 due to proteasome-independent inhibition of M-calpain

  👤 Schneider, Martha 👤 Ackermann, Kerstin 👤 Stuart, Melissa 👤 Wex, Claudia 👤 Protzer, Ulrike 👤 Schätzl, Hermann M. 👤 Gilch, Sabine ⏰ 2012 📚 Journal of Virology

• COVID-19 And Older Adults: What We Know.

  👤 Shahid, Zainab 👤 Kalayanamitra, Ricci 👤 McClafferty, Brendan 👤 Kepko, Douglas 👤 Ramgobin, Devyani 👤 Patel, Ravi 👤 Aggarwal, Chander Shekher 👤 Vunnam, Rama Rao 👤 Sahu, Nitasa 👤 Bhatt, Dhirisha 👤 Jones, Kirk 👤 Golamari, Reshma 👤 Jain, Rohit ⏰ 2020 📚 J Am Geriatr Soc

• Identifying epitopes responsible for neutralizing antibody and DC-SIGN binding on the spike glycoprotein of the severe acute respiratory syndrome coronavirus

  👤 Shih, Yi Ping 👤 Chen, Chia Yen 👤 Liu, Shih Jen 👤 Chen, Kuan Hsuan 👤 Lee, Yuan Ming 👤 Chao, Yu Chan 👤 Chen, Yi Ming Arthur ⏰ 2006 📚 Journal of Virology

• A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

  👤 Shulla, Ana 👤 Heald-Sargent, Taylor 👤 Subramanya, Gitanjali 👤 Zhao, Jincun 👤 Perlman, Stanley 👤 Gallagher, Tom ⏰ 2011 📚 Journal of Virology

• Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2

  👤 Song, Wenfei 👤 Gui, Miao 👤 Wang, Xinquan 👤 Xiang, Ye ⏰ 2018 📚 PLoS Pathogens

• COVID-19, ACE2 and the Cardiovascular Consequences.

  👤 South, Andrew Michael 👤 Diz, Debra 👤 Chappell, Mark C ⏰ 2020 📚 Am J Physiol Heart Circ Physiol

• Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness

  👤 Sui, Jianhua 👤 Deming, Meagan 👤 Rockx, Barry 👤 Liddington, Robert C. 👤 Zhu, Quan Karen 👤 Baric, Ralph S. 👤 Marasco, Wayne A. ⏰ 2014 📚 Journal of Virology

• Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association

  👤 Sui, Jianhua 👤 Li, Wenhui 👤 Murakami, Akikazu 👤 Tamin, Azaibi 👤 Matthews, Leslie J. 👤 Wong, Swee Kee 👤 Moore, Michael J. 👤 Tallarico, Aimee St Clair 👤 Olurinde, Mobolaji 👤 Choe, Hyeryun 👤 Anderson, Larry J. 👤 Bellini, William J. 👤 Farzan, Michael 👤 Marasco, Wayne A. ⏰ 2004 📚 Proceedings of the National Academy of Sciences of the United States of America

• Potential Factors Influencing Repeated SARS Outbreaks in China.

  👤 Sun, Zhong 👤 Thilakavathy, Karuppiah 👤 Kumar, S Suresh 👤 He, Guozhong 👤 Liu, Shi V ⏰ 2020 📚 Int J Environ Res Public Health

• Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine.

  👤 Tai, Wanbo 👤 He, Lei 👤 Zhang, Xiujuan 👤 Pu, Jing 👤 Voronin, Denis 👤 Jiang, Shibo 👤 Zhou, Yusen 👤 Du, Lanying ⏰ 2020 📚 Cell Mol Immunol

• A consensus statement on the use of angiotensin receptor blockers and angiotensin converting enzyme inhibitors in relation to COVID-19 (corona virus disease 2019).

  👤 Talreja, Hari 👤 Tan, Jasmine 👤 Dawes, Matt 👤 Supershad, Sharen 👤 Rabindranath, Kannaiyan 👤 Fisher, James 👤 Valappil, Sajed 👤 van der Merwe, Veronica 👤 Wong, Lisa 👤 van der Merwe, Walter 👤 Paton, Julian ⏰ 2020 📚 N Z Med J

• [2019-nCoV: new challenges from coronavirus].

  👤 Tian, H Y ⏰ 2020 📚 Zhonghua Yu Fang Yi Xue Za Zhi

• Apical entry and release of severe acute respiratory syndrome-associated coronavirus in polarized Calu-3 lung epithelial cells

  👤 Tseng, Chien Te K. 👤 Tseng, Jennifer 👤 Perrone, Lucy 👤 Worthy, Melissa 👤 Popov, Vsevolod 👤 Peters, Clarence J. ⏰ 2005 📚 Journal of Virology

• Pathology of experimental SARS coronavirus infection in cats and ferrets

  👤 Van Den Brand, J. M.A. 👤 L.haagmans, B. 👤 Leijten, L. 👤 Van Riel, D. 👤 E.martina, B. E. 👤 Osterhaus, A. D.M.E. 👤 Kuiken, T. ⏰ 2008 📚 Veterinary Pathology

• Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

  👤 Vincent, Martin J. 👤 Bergeron, Eric 👤 Benjannet, Suzanne 👤 Erickson, Bobbie R. 👤 Rollin, Pierre E. 👤 Ksiazek, Thomas G. 👤 Seidah, Nabil G. 👤 Nichol, Stuart T. ⏰ 2005 📚 Virology Journal

• Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus.

  👤 Wan, Yushun 👤 Shang, Jian 👤 Graham, Rachel 👤 Baric, Ralph S 👤 Li, Fang ⏰ 2020 📚 J Virol

• SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway

  👤 Wang, Hongliang 👤 Yang, Peng 👤 Liu, Kangtai 👤 Guo, Feng 👤 Zhang, Yanli 👤 Zhang, Gongyi 👤 Jiang, Chengyu ⏰ 2008 📚 Cell Research

• Expression cloning of functional receptor used by SARS coronavirus

  👤 Wang, Peigang 👤 Chen, Jian 👤 Zheng, Aihua 👤 Nie, Yuchun 👤 Shi, Xuanling 👤 Wang, Wei 👤 Wang, Guangwen 👤 Luo, Min 👤 Liu, Huijun 👤 Tan, Lei 👤 Song, Xijun 👤 Wang, Zai 👤 Yin, Xiaolei 👤 Qu, Xiuxia 👤 Wang, Xiaojing 👤 Qing, Tingting 👤 Ding, Mingxiao 👤 Deng, Hongkui ⏰ 2004 📚 Biochemical and Biophysical Research Communications

• Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.

  👤 Wrapp, Daniel 👤 Wang, Nianshuang 👤 Corbett, Kizzmekia S 👤 Goldsmith, Jory A 👤 Hsieh, Ching-Lin 👤 Abiona, Olubukola 👤 Graham, Barney S 👤 McLellan, Jason S ⏰ 2020 📚 Science

• A virus-binding hot spot on human angiotensin-converting enzyme 2 is critical for binding of two different coronaviruses

  👤 Wu, Kailang 👤 Chen, Lang 👤 Peng, Guiqing 👤 Zhou, Wenbo 👤 Pennell, Christopher A. 👤 Mansky, Louis M. 👤 Geraghty, Robert J. 👤 Li, Fang ⏰ 2011 📚 Journal of Virology

• Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor

  👤 Wu, Kailang 👤 Li, Weikai 👤 Peng, Guiqing 👤 Li, Fang ⏰ 2009 📚 Proceedings of the National Academy of Sciences of the United States of America

• Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus

  👤 Wu, Kailang 👤 Peng, Guiqing 👤 Wilken, Matthew 👤 Geraghty, Robert J. 👤 Li, Fang ⏰ 2012 📚 Journal of Biological Chemistry

• Angiotensin-converting enzyme 2 (ACE2) from raccoon dog can serve as an efficient receptor for the spike protein of severe acute respiratory syndrome coronavirus

  👤 Xu, Lili 👤 Zhang, Yanfang 👤 Liu, Yun 👤 Chen, Zhiwei 👤 Deng, Hongkui 👤 Ma, Zhongbin 👤 Wang, Hualin 👤 Hu, Zhihong 👤 Deng, Fei ⏰ 2009 📚 Journal of General Virology

• Susceptibility of human and rat neural cell lines to infection by SARS-coronavirus

  👤 Yamashita, Makiko 👤 Yamate, Masanobu 👤 Li, Gui Mei 👤 Ikuta, Kazuyoshi ⏰ 2005 📚 Biochemical and Biophysical Research Communications

• Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses

  👤 Yang, Zhi Yong 👤 Werner, Heidi C. 👤 Kong, Wing Pui 👤 Leung, Kwanyee 👤 Traggiai, Elisabetta 👤 Lanzavecchia, Antonio 👤 Nabel, Gary J. ⏰ 2005 📚 Proceedings of the National Academy of Sciences of the United States of America

• Single amino acid substitutions in the severe acute respiratory syndrome coronavirus spike glycoprotein determine viral entry and immunogenicity of a major neutralizing domain

  👤 Yi, Christopher E. 👤 Ba, Lei 👤 Zhang, Linqi 👤 Ho, David D. 👤 Chen, Zhiwei ⏰ 2005 📚 Journal of Virology

• Differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human angiotensin-converting enzyme 2

  👤 Yoshikawa, Naoko 👤 Yoshikawa, Tomoki 👤 Hill, Terence 👤 Huang, Cheng 👤 Watts, Douglas M. 👤 Makino, Shinji 👤 Milligan, Gregg 👤 Chan, Tehsheng 👤 Peters, Clarence J. 👤 Tseng, Chien Te K. ⏰ 2009 📚 Journal of Virology

• Computational simulation of interactions between SARS coronavirus spike mutants and host species-specific receptors

  👤 Zhang, Yuan 👤 Zheng, Nan 👤 Nan, Peng 👤 Cao, Ying 👤 Hasegawa, Masami 👤 Zhong, Yang ⏰ 2007 📚 Computational Biology and Chemistry

• Screening and identification of severe acute respiratory syndrome-associated coronavirus-specific CTL epitopes

  👤 Zhou, Minghai 👤 Xu, Dongping 👤 Li, Xiaojuan 👤 Li, Hongtao 👤 Shan, Ming 👤 Tang, Jiaren 👤 Wang, Min 👤 Wang, Fu Sheng 👤 Zhu, Xiaodong 👤 Tao, Hua 👤 He, Wei 👤 Tien, Po 👤 Gao, George F. ⏰ 2006 📚 Journal of Immunology

• Possible causes for decreased susceptibility of children to coronavirus.

  👤 Zhu, Liqin 👤 Lu, Xiaoqing 👤 Chen, Lu ⏰ 2020 📚 Pediatr Res