π Journal of Biological Chemistry
Articles (53)
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Crystal structure of the middle east respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression
π€ Bailey-Elkin, Ben A. π€ Knaap, Robert C.M. π€ Johnson, Garrett G. π€ Dalebout, Tim J. π€ Ninaber, Dennis K. π€ Van Kasteren, Puck B. π€ Bredenbeek, Peter J. π€ Snijder, Eric J. π€ Kikkert, Marjolein π€ Mark, Brian L. β° 2014 π Journal of Biological Chemistry
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Elastase-mediated activation of the severe acute respiratory syndrome coronavirus spike protein at discrete sites within the S2 domain
π€ Belouzard, Sandrine π€ Madu, Ikenna π€ Whittaker, Gary R. β° 2010 π Journal of Biological Chemistry
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Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15
π€ Bhardwaj, Kanchan π€ Palaninathan, Satheesh π€ Alcantara, Joanna Maria Ortiz π€ Yi, Lillian Li π€ Guarino, Linda π€ Sacchettini, James C. π€ Kao, C. Cheng β° 2008 π Journal of Biological Chemistry
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Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes
π€ Bouvet, MickaΓ«l π€ Lugari, Adrien π€ Posthuma, Clara C. π€ Zevenhoven, Jessika C. π€ Bernard, StΓ©phanie π€ Betzi, StΓ©phane π€ Imbert, Isabelle π€ Canard, Bruno π€ Guillemot, Jean Claude π€ LΓ©cine, Patrick π€ Pfefferle, Susanne π€ Drosten, Christian π€ Snijder, Eric J. π€ Decroly, Etienne π€ Morelli, Xavier β° 2014 π Journal of Biological Chemistry
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Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization: Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations
π€ Chen, Shuai π€ Chen, Lili π€ Tan, Jinzhi π€ Chen, Jing π€ Du, Li π€ Sun, Tao π€ Shen, Jianhua π€ Chen, Kaixian π€ Jiang, Hualiang π€ Shen, Xu β° 2005 π Journal of Biological Chemistry
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Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: Crystal structure with molecular dynamics simulations
π€ Chen, Shuai π€ Hu, Tiancen π€ Zhang, Jian π€ Chen, Jing π€ Chen, Kaixian π€ Ding, Jianping π€ Jiang, Hualiang π€ Shen, Xu β° 2008 π Journal of Biological Chemistry
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Macro domain from middle east respiratory syndrome coronavirus (MERS-CoV) is an efficient ADP-ribose binding module: Crystal structure and biochemical studies
π€ Cho, Chao Cheng π€ Lin, Meng Hsuan π€ Chuang, Chien Ying π€ Hsu, Chun Hua β° 2016 π Journal of Biological Chemistry
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Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells
π€ Chu, Hin π€ Chan, Che Man π€ Zhang, Xi π€ Wang, Yixin π€ Yuan, Shuofeng π€ Zhou, Jie π€ Au-Yeung, Rex Kwok Him π€ Sze, Kong Hung π€ Yang, Dong π€ Shuai, Huiping π€ Hou, Yuxin π€ Li, Cun π€ Zhao, Xiaoyu π€ Poon, Vincent Kwok Man π€ Leung, Sze Pui π€ Yeung, Man Lung π€ Yan, Jinghua π€ Lu, Guangwen π€ Jin, Dong Yan π€ Gao, George Fu π€ Chan, Jasper Fuk Woo π€ Yuen, Kwok Yung β° 2018 π Journal of Biological Chemistry
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Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus
π€ Devaraj, Santhana G. π€ Wang, Nan π€ Chen, Zhongbin π€ Chen, Zihong π€ Tseng, Monica π€ Barretto, Naina π€ Lin, Rongtuan π€ Peters, Clarence J. π€ Tseng, Chien Te K. π€ Baker, Susan C. π€ Li, Kui β° 2007 π Journal of Biological Chemistry
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Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase
π€ Fan, Keqiang π€ Wei, Ping π€ Feng, Qian π€ Chen, Sidi π€ Huang, Changkang π€ Ma, Liang π€ Lai, Bing π€ Pei, Jianfeng π€ Liu, Ying π€ Chen, Jianguo π€ Lai, Luhua β° 2004 π Journal of Biological Chemistry
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Solution structure of the severe acute respiratory syndrome-coronavirus heptad repeat 2 domain in the prefusion state
π€ Hakansson-McReynolds, Susanna π€ Jiang, Shaokai π€ Rong, Lijun π€ Caffrey, Michael β° 2006 π Journal of Biological Chemistry
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Critical assessment of important regions in the subunit association and catalytic action of the severe acute respiratory syndrome coronavirus main protease
π€ Hsu, Wen Chi π€ Chang, Hui Chuan π€ Chou, Chi Yuan π€ Tsai, Pui Jen π€ Lin, Pei In π€ Chang, Gu Gang β° 2005 π Journal of Biological Chemistry
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SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells
π€ Huang, I. Chueh π€ Bosch, Berend Jan π€ Li, Fang π€ Li, Wenhui π€ Kyoung, Hoa Lee π€ Ghiran, Sorina π€ Vasilieva, Natalya π€ Dermody, Terence S. π€ Harrison, Stephen C. π€ Dormitzer, Philip R. π€ Farzan, Michael π€ Rottier, Peter J.M. π€ Choe, Hyeryun β° 2006 π Journal of Biological Chemistry
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Tumor necrosis factor-Ξ± convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2)
π€ Lambert, Daniel W. π€ Yarski, Mike π€ Warner, Fiona J. π€ Thornhill, Paul π€ Parkin, Edward T. π€ Smith, A. Ian π€ Hooper, Nigel M. π€ Turner, Anthony J. β° 2005 π Journal of Biological Chemistry
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Quaternary structure of coronavirus spikes in complex with carcinoembryonic antigen-related cell adhesion molecule cellular receptors
π€ Lewicki, Daniel N. π€ Gallagher, Thomas M. β° 2002 π Journal of Biological Chemistry
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Maturation mechanism of severe acute respiratory syndrome (SARS) coronavirus 3C-like proteinase
π€ Li, Chunmei π€ Qi, Yifei π€ Teng, Xin π€ Yang, Zongchang π€ Wei, Ping π€ Zhang, Changsheng π€ Tan, Lei π€ Zhou, Lu π€ Liu, Ying π€ Lai, Luhua β° 2010 π Journal of Biological Chemistry
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Structure of a conserved golgi complex-targeting signal in coronavirus envelope proteins
π€ Li, Yan π€ Surya, Wahyu π€ Claudine, Stephanie π€ Torres, Jaume β° 2014 π Journal of Biological Chemistry
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mRNA display design of fibronectin-based intrabodies that detect and inhibit severe acute respiratory syndrome coronavirus nucleocapsid protein
π€ Liao, Hsiang I. π€ Olson, C. Anders π€ Hwang, Seungmin π€ Deng, Hongyu π€ Wong, Elaine π€ Baric, Ralph S. π€ Roberts, Richard W. π€ Sun, Ren β° 2009 π Journal of Biological Chemistry
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The missing link in coronavirus assembly. Retention of the avian coronavirus infectious bronchitis virus envelope protein in the pre-Golgi compartments and physical interaction between the envelope and membrane proteins
π€ Lim, K. P. π€ Liu, D. X. β° 2001 π Journal of Biological Chemistry
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Cell entry of porcine epidemic diarrhea coronavirus is activated by lysosomal proteases
π€ Liu, Chang π€ Ma, Yuanmei π€ Yang, Yang π€ Zheng, Yuan π€ Shang, Jian π€ Zhou, Yusen π€ Jiang, Shibo π€ Du, Lanying π€ Li, Jianrong π€ Li, Fang β° 2016 π Journal of Biological Chemistry
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Molecular mapping of the RNA cap 2β²-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16
π€ Lugari, Adrien π€ Betzi, Stephane π€ Decroly, Etienne π€ Bonnaud, Emmanuel π€ Hermant, AurΓ©lie π€ Guillemot, Jean Claude π€ Debarnot, Claire π€ Borg, Jean Paul π€ Bouvet, MickaΓ«l π€ Canard, Bruno π€ Morelli, Xavier π€ LΓ©cine, Patrick β° 2010 π Journal of Biological Chemistry
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Glycosylation of the viral attachment protein of avian coronavirus is essential for host cell and receptor binding
π€ Parsons, Lisa M. π€ Bouwman, Kim M. π€ Azurmendi, Hugo π€ De Vries, Robert P. π€ Cipollo, John F. π€ Verheije, Monique H. β° 2019 π Journal of Biological Chemistry
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Crystal structure of bovine coronavirus spike protein lectin domain
π€ Peng, Guiqing π€ Xu, Liqing π€ Lin, Yi Lun π€ Chen, Lang π€ Pasquarella, Joseph R. π€ Holmes, Kathryn V. π€ Li, Fang β° 2012 π Journal of Biological Chemistry
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Structural and molecular evidence suggesting coronavirus-driven evolution of mouse receptor
π€ Peng, Guiqing π€ Yang, Yang π€ Pasquarella, Joseph R. π€ Xu, Liqing π€ Qian, Zhaohui π€ Holmes, Kathryn V. π€ Li, Fang β° 2017 π Journal of Biological Chemistry
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The C-terminal domain of the MERS coronavirusMprotein contains a trans-Golgi network localization signal
π€ Perrier, Anabelle π€ Bonnin, Ariane π€ Desmarets, Lowiese π€ Danneels, Adeline π€ Goffard, Anne π€ RouillΓ©, Yves π€ Dubuisson, Jean π€ Belouzard, Sandrine β° 2019 π Journal of Biological Chemistry
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Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody
π€ Prabakaran, Ponraj π€ Gan, Jianhua π€ Feng, Yang π€ Zhu, Zhongyu π€ Choudhry, Vidita π€ Xiao, Xiaodong π€ Ji, Xinhua π€ Dimitrov, Dimiter S. β° 2006 π Journal of Biological Chemistry
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Coronavirus Replication Complex Formation Utilizes Components of Cellular Autophagy
π€ Prentice, Erik π€ Jerome, W. Gray π€ Yoshimori, Tamotsu π€ Mizushima, Noboru π€ Denison, Mark R. β° 2004 π Journal of Biological Chemistry
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Identification of two critical amino acid residues of the severe acute respiratory syndrome coronavirus spike protein for its variation in zoonotic tropism transition via a double substitution strategy
π€ Qu, Xiu Xia π€ Hao, Pei π€ Song, Xi Jun π€ Jiang, Si Ming π€ Liu, Yan Xia π€ Wang, Pei Gang π€ Rao, Xi π€ Song, Huai Dong π€ Wang, Sheng Yue π€ Zuo, Yu π€ Zheng, Ai Hua π€ Luo, Min π€ Wang, Hua Lin π€ Deng, Fei π€ Wang, Han Zhong π€ Hu, Zhi Hong π€ Ding, Ming Xiao π€ Zhao, Guo Ping π€ Deng, Hong Kui β° 2005 π Journal of Biological Chemistry
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A novel sorting signal for intracellular localization is present in the S protein of a porcine coronavirus but absent from severe acute respiratory syndrome-associated coronavirus
π€ Schwegmann-Wessels, Christel π€ Al-Falah, Marwan π€ Escors, David π€ Wang, Zai π€ Zimmer, Gert π€ Deng, Hongkui π€ Enjuanes, Luis π€ Naim, Hassan Y. π€ Herrler, Georg β° 2004 π Journal of Biological Chemistry
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A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence
π€ Shen, Zhou π€ Wang, Gang π€ Yang, Yiling π€ Shi, Jiale π€ Fang, Liurong π€ Li, Fang π€ Xiao, Shaobo π€ Fu, Zhen F. π€ Peng, Guiqing β° 2019 π Journal of Biological Chemistry
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Role of spike protein endodomains in regulating coronavirus entry
π€ Shulla, Ana π€ Gallagher, Tom β° 2009 π Journal of Biological Chemistry
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Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding theformation of TRAF3Β·TANKΒ·TBK1/IKKΞ΅ complex
π€ Siu, Kam Leung π€ Kok, Kin Hang π€ Ng, Ming Him James π€ Poon, Vincent K.M. π€ Yuen, Kwok Yung π€ Zheng, Bo Jian π€ Jin, Dong Yan β° 2009 π Journal of Biological Chemistry
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Nidovirus sialate-O-acetylesterases: Evolution and substrate specificity of coronaviral and toroviral receptor-destroying enzymes
π€ Smits, Saskia L. π€ Gerwig, Gerrit J. π€ Van Vliet, Arno L.W. π€ Lissenberg, Arjen π€ Briza, Peter π€ Kamerling, Johannis P. π€ Vlasak, Reinhard π€ De Groot, Raoul J. β° 2005 π Journal of Biological Chemistry
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The nucleocapsid protein of severe acute respiratory syndrome-coronavirus inhibits the activity of cyclin-cyclin-dependent kinase complex and blocks S phase progression in mammalian cells
π€ Surjit, Milan π€ Liu, Boping π€ Chow, Vincent T.K. π€ Lal, Sunil K. β° 2006 π Journal of Biological Chemistry
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The severe acute respiratory syndrome (SARS) coronavirus NTPasefhelicase belongs to a distinct class of 5β² to 3β² viral helicases
π€ Tanner, Julian A. π€ Watt, Rory M. π€ Chai, Yu Bo π€ Lu, Lin Yu π€ Lin, Marie C. π€ Peiris, J. S.Malik π€ Poon, Leo L.M. π€ Kung, Hsiang Fu π€ Huang, Jian Dong β° 2003 π Journal of Biological Chemistry
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Ligand-induced dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 protease (3CLpro): Implications for nsp5 regulation and the development of antivirals
π€ Tomar, Sakshi π€ Johnston, Melanie L. π€ John, Sarah E.St π€ Osswald, Heather L. π€ Nyalapatla, Prasanth R. π€ Paul, Lake N. π€ Ghosh, Arun K. π€ Denison, Mark R. π€ Mesecar, Andrew D. β° 2015 π Journal of Biological Chemistry
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Structural characterization of the SARS-coronavirus spike S fusion protein core
π€ Tripet, Brian π€ Howard, Megan W. π€ Jobling, Michael π€ Holmes, Randall K. π€ Holmes, Kathryn V. π€ Hodges, Robert S. β° 2004 π Journal of Biological Chemistry
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Self-assembly of severe acute respiratory syndrome coronavirus membrane protein
π€ Tseng, Ying Tzu π€ Wang, Shiu Mei π€ Huang, Kuo Jung π€ I-Ru Lee, Amber π€ Chiang, Chien Cheng π€ Wang, Chin Tien β° 2010 π Journal of Biological Chemistry
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A 193-Amino Acid Fragment of the SARS Coronavirus S Protein Efficiently Binds Angiotensin-converting Enzyme 2
π€ Wong, Swee Kee π€ Li, Wenhui π€ Moore, Michael J. π€ Choe, Hyeryun π€ Farzan, Michael β° 2004 π Journal of Biological Chemistry
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Glycogen synthase kinase-3 regulates the phosphorylation of severe acute respiratory syndrome coronavirus mucleocapsid protein and viral replication
π€ Wu, Chia Hsin π€ Yeh, Shiou Hwei π€ Tsay, Yeou Guang π€ Shieh, Ya Hsiung π€ Kao, Chuan Liang π€ Chen, Yen Shun π€ Wang, Sheng Han π€ Kuo, Ti Jung π€ Chen, Ding Shinn π€ Chen, Pei Jer β° 2009 π Journal of Biological Chemistry
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Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus
π€ Wu, Kailang π€ Peng, Guiqing π€ Wilken, Matthew π€ Geraghty, Robert J. π€ Li, Fang β° 2012 π Journal of Biological Chemistry
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Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase Ξ΄
π€ Xu, Ling Hui π€ Huang, Mei π€ Fang, Shou Guo π€ Liu, Ding Xiang β° 2011 π Journal of Biological Chemistry
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Structural basis for coronavirus-mediated membrane fusion: Crystal structure of mouse hepatitis virus spike protein fusion core
π€ Xu, Yanhui π€ Liu, Yiwei π€ Lou, Zhiyong π€ Qin, Lan π€ Li, Xu π€ Bai, Zhihong π€ Pang, Hai π€ Tien, Po π€ Gao, George F. π€ Rao, Zihe β° 2004 π Journal of Biological Chemistry
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Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core
π€ Xu, Yanhui π€ Lou, Zhiyong π€ Liu, Yiwei π€ Pang, Hai π€ Tien, Po π€ Gao, George F. π€ Rao, Zihe β° 2004 π Journal of Biological Chemistry
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Phosphatidylinositol 4-kinase IIIΞ² is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry
π€ Yang, Ning π€ Ping, Ma π€ Lang, Jianshe π€ Zhang, Yanli π€ Deng, Jiejie π€ Ju, Xiangwu π€ Zhang, Gongyi π€ Jiang, Chengyu β° 2012 π Journal of Biological Chemistry
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Recombinant severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein forms a dimer through its C-terminal domain
π€ Yu, I. Mei π€ Gustafson, Christin L.T. π€ Diao, Jianbo π€ Burgner II, John W. π€ Li, Zhihong π€ Zhang, Jingqiang π€ Chen, Jue β° 2005 π Journal of Biological Chemistry
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Crystal structure of the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein dimerization domain reveals evolutionary linkage between Corona- and Arteriviridae
π€ Yu, I. Mei π€ Oldham, Michael L. π€ Zhang, Jingqiang π€ Chen, Jue β° 2006 π Journal of Biological Chemistry
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P53 degradation by a coronavirus papain-like protease suppresses type I interferon signaling
π€ Yuan, Lin π€ Chen, Zhongbin π€ Song, Shanshan π€ Wang, Shan π€ Tian, Chunyan π€ Xing, Guichun π€ Chen, Xiaojuan π€ Xiao, Zhi Xiong π€ He, Fuchu π€ Zhang, Lingqiang β° 2015 π Journal of Biological Chemistry
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Porcine deltacoronavirus enters cells via two pathways: A protease-mediated one at the cell surface and another facilitated by cathepsins in the endosome
π€ Zhang, Jialin π€ Chen, Jianfei π€ Shi, Da π€ Shi, Hongyan π€ Zhang, Xin π€ Liu, Jianbo π€ Cao, Liyan π€ Zhu, Xiangdong π€ Liu, Ye π€ Wang, Xiaobo π€ Ji, Zhaoyang π€ Feng, Li β° 2019 π Journal of Biological Chemistry
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Severe acute respiratory syndrome-associated coronavirus nucleocapsid protein interacts with Smad3 and modulates transforming growth factor-Ξ² signaling
π€ Zhao, Xingang π€ Nicholls, John M. π€ Chen, Ye Guang β° 2008 π Journal of Biological Chemistry
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Insight into the evolution of nidovirus endoribonuclease based on the finding that nsp15 from porcine Deltacoronavirus functions as a dimer
π€ Zheng, Anjun π€ Shi, Yuejun π€ Shen, Zhou π€ Wang, Gang π€ Shi, Jiale π€ Xiong, Qiqi π€ Fang, Liurong π€ Xiao, Shaobo π€ Fu, Zhen F. π€ Peng, Guiqing β° 2018 π Journal of Biological Chemistry
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Glycopeptide antibiotics potently inhibit cathepsin l in the late endosome/lysosome and block the entry of ebola virus, middle east respiratory syndrome coronavirus (MERS-CoV), and severe acute respiratory syndrome coronavirus (SARS-CoV)
π€ Zhou, Nan π€ Pan, Ting π€ Zhang, Junsong π€ Li, Qianwen π€ Zhang, Xue π€ Bai, Chuan π€ Huang, Feng π€ Peng, Tao π€ Zhang, Jianhua π€ Liu, Chao π€ Tao, Liang π€ Zhang, Hui β° 2016 π Journal of Biological Chemistry
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TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1
π€ Zmora, Pawel π€ Hoffmann, Markus π€ Kollmus, Heike π€ Moldenhauer, Anna Sophie π€ Danov, Olga π€ Braun, Armin π€ Winkler, Michael π€ Schughart, Klaus π€ Stefan PΓΆhlmann, X. β° 2018 π Journal of Biological Chemistry