π€ Jiang, Hualiang
Keywords
Articles (15)
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Discovering severe acute respiratory syndrome coronavirus 3CL protease inhibitors: Virtual screening, surface plasmon resonance, and fluorescence resonance energy transfer assays
π€ Chen, Lili π€ Chen, Shuai π€ Gui, Chunshan π€ Shen, Jianhua π€ Shen, Xu π€ Jiang, Hualiang β° 2006 π Journal of Biomolecular Screening
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Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro
π€ Chen, Lili π€ Gui, Chunshan π€ Luo, Xiaomin π€ Yang, Qingang π€ GΓΌnther, Stephan π€ Scandella, Elke π€ Drosten, Christian π€ Bai, Donglu π€ He, Xichang π€ Ludewig, Burkhard π€ Chen, Jing π€ Luo, Haibin π€ Yang, Yiming π€ Yang, Yifu π€ Zou, Jianping π€ Thiel, Volker π€ Chen, Kaixian π€ Shen, Jianhua π€ Shen, Xu π€ Jiang, Hualiang β° 2005 π Journal of Virology
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Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization: Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations
π€ Chen, Shuai π€ Chen, Lili π€ Tan, Jinzhi π€ Chen, Jing π€ Du, Li π€ Sun, Tao π€ Shen, Jianhua π€ Chen, Kaixian π€ Jiang, Hualiang π€ Shen, Xu β° 2005 π Journal of Biological Chemistry
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Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: Crystal structure with molecular dynamics simulations
π€ Chen, Shuai π€ Hu, Tiancen π€ Zhang, Jian π€ Chen, Jing π€ Chen, Kaixian π€ Ding, Jianping π€ Jiang, Hualiang π€ Shen, Xu β° 2008 π Journal of Biological Chemistry
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An overall picture of SARS coronavirus (SARS-CoV) genome-encoded major proteins: Structures, functions and drug development
π€ Chen, Shuai π€ Luo, Haibin π€ Chen, Lili π€ Chen, Jing π€ Shen, Jianhua π€ Zhu, Weiliang π€ Chen, Kaixian π€ Shen, Xu π€ Jiang, Hualiang β° 2006 π Current Pharmaceutical Design
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Residues on the dimer interface of SARS coronavirus 3C-like protease: Dimer stability characterization and enzyme catalytic activity analysis
π€ Chen, Shuai π€ Zhang, Jian π€ Hu, Tiancen π€ Chen, Kaixian π€ Jiang, Hualiang π€ Shen, Xu β° 2008 π Journal of Biochemistry
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Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure
π€ Hu, Tiancen π€ Zhang, Yu π€ Li, Lianwei π€ Wang, Kuifeng π€ Chen, Shuai π€ Chen, Jing π€ Ding, Jianping π€ Jiang, Hualiang π€ Shen, Xu β° 2009 π Virology
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Structure of M(pro) from COVID-19 virus and discovery of its inhibitors.
π€ Jin, Zhenming π€ Du, Xiaoyu π€ Xu, Yechun π€ Deng, Yongqiang π€ Liu, Meiqin π€ Zhao, Yao π€ Zhang, Bing π€ Li, Xiaofeng π€ Zhang, Leike π€ Peng, Chao π€ Duan, Yinkai π€ Yu, Jing π€ Wang, Lin π€ Yang, Kailin π€ Liu, Fengjiang π€ Jiang, Rendi π€ Yang, Xinglou π€ You, Tian π€ Liu, Xiaoce π€ Yang, Xiuna π€ Bai, Fang π€ Liu, Hong π€ Liu, Xiang π€ Guddat, Luke W π€ Xu, Wenqing π€ Xiao, Gengfu π€ Qin, Chengfeng π€ Shi, Zhengli π€ Jiang, Hualiang π€ Rao, Zihe π€ Yang, Haitao β° 2020 π Nature
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Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A
π€ Luo, Cheng π€ Luo, Haibin π€ Zheng, Suxin π€ Gui, Chunshan π€ Yue, Liduo π€ Yu, Changying π€ Sun, Tao π€ He, Peilan π€ Chen, Jing π€ Shen, Jianhua π€ Luo, Xiaomin π€ Li, Yixue π€ Liu, Hong π€ Bai, Donglu π€ Shen, Jingkang π€ Yang, Yiming π€ Li, Fangqiu π€ Zuo, Jianping π€ Hilgenfeld, Rolf π€ Pei, Gang π€ Chen, Kaixian π€ Shen, Xu π€ Jiang, Hualiang β° 2004 π Biochemical and Biophysical Research Communications
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Carboxyl terminus of severe acute respiratory syndrome coronavirus nucleocapsid protein: Self-association analysis and nucleic acid binding characterization
π€ Luo, Haibin π€ Chen, Jing π€ Chen, Kaixian π€ Shen, Xu π€ Jiang, Hualiang β° 2006 π Biochemistry
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The nucleocapsid protein of SARS coronavirus has a high binding affinity to the human cellular heterogeneous nuclear ribonucleoprotein A1
π€ Luo, Haibin π€ Chen, Qing π€ Chen, Jing π€ Chen, Kaixian π€ Shen, Xu π€ Jiang, Hualiang β° 2005 π FEBS Letters
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Severe acute respiratory syndrome coronavirus membrane protein interacts with nucleocapsid protein mostly through their carboxyl termini by electrostatic attraction
π€ Luo, Haibin π€ Wu, Dalei π€ Shen, Can π€ Chen, Kaixian π€ Shen, Xu π€ Jiang, Hualiang β° 2006 π International Journal of Biochemistry and Cell Biology
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SR-rich motif plays a pivotal role in recombinant SARS coronavirus nucleocapsid protein multimerization
π€ Luo, Haibin π€ Ye, Fei π€ Chen, Kaixian π€ Shen, Xu π€ Jiang, Hualiang β° 2005 π Biochemistry
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Molecular cloning, expression, purification, and mass spectrometric characterization of 3C-like protease of SARS coronavirus
π€ Sun, Haifang π€ Luo, Haibin π€ Yu, Changying π€ Sun, Tao π€ Chen, Jing π€ Peng, Shuying π€ Qin, Jun π€ Shen, Jianhua π€ Yang, Yiming π€ Xie, Youhua π€ Chen, Kaixian π€ Wang, Yuan π€ Shen, Xu π€ Jiang, Hualiang β° 2003 π Protein Expression and Purification
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Folding of the SARS coronavirus spike glycoprotein immunological fragment (SARS_S1B): Thermodynamic and kinetic investigation correlating with three-dimensional structural modeling
π€ Yu, Changying π€ Gui, Chunshan π€ Luo, Haibin π€ Chen, Lili π€ Zhang, Liang π€ Yu, Hao π€ Yang, Sheng π€ Jiang, Weihong π€ Shen, Jianhua π€ Shen, Xu π€ Jiang, Hualiang β° 2005 π Biochemistry