π Life cycle
Articles (63)
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Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase
π€ Adedeji, Adeyemi O. π€ Singh, Kamalendra π€ Calcaterra, Nicholas E. π€ DeDiego, Marta L. π€ Enjuanes, Luis π€ Weiss, Susan π€ Sarafianos, Stefan G. β° 2012 π Antimicrobial Agents and Chemotherapy
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Teicoplanin: an alternative drug for the treatment of COVID-19?
π€ Baron, Sophie Alexandra π€ Devaux, Christian π€ Colson, Philippe π€ Raoult, Didier π€ Rolain, Jean-Marc β° 2020 π Int J Antimicrob Agents
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RNA 3β²-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex
π€ Bouvet, MickaΓ«l π€ Imbert, Isabelle π€ Subissi, Lorenzo π€ Gluais, Laure π€ Canard, Bruno π€ Decroly, Etienne β° 2012 π Proceedings of the National Academy of Sciences of the United States of America
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Expression, purification and characterization of recombinant severe acute respiratory syndrome coronavirus non-structural protein 1
π€ Brucz, Kimberly π€ Miknis, Zachary J. π€ Schultz, L. Wayne π€ Umland, Timothy C. β° 2007 π Protein Expression and Purification
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Suppression of coronavirus replication by inhibition of the MEK signaling pathway
π€ Cai, Yingyun π€ Liu, Yin π€ Zhang, Xuming β° 2007 π Journal of Virology
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Spike protein, S, of human coronavirus HKU1: Role in viral life cycle and application in antibody detection
π€ Chan, Che Man π€ Woo, Patrick C.Y. π€ Lau, Susanna K.P. π€ Tse, Herman π€ Chen, Hong Lin π€ Li, Feng π€ Zheng, Bo Jian π€ Chen, Ling π€ Huang, Jian Dong π€ Yuen, Kwok Yung β° 2008 π Experimental Biology and Medicine
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Modular organization of SARS coronavirus nucleocapsid protein
π€ Chang, Chung Ke π€ Sue, Shih Che π€ Yu, Tsan Hung π€ Hsieh, Chiu Min π€ Tsai, Cheng Kun π€ Chiang, Yen Chieh π€ Lee, Shin Jye π€ Hsiao, Hsin Hao π€ Wu, Wen Jin π€ Chang, Wei Lun π€ Lin, Chun Hung π€ Huang, Tai Huang β° 2006 π Journal of Biomedical Science
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Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro
π€ Chen, Lili π€ Gui, Chunshan π€ Luo, Xiaomin π€ Yang, Qingang π€ GΓΌnther, Stephan π€ Scandella, Elke π€ Drosten, Christian π€ Bai, Donglu π€ He, Xichang π€ Ludewig, Burkhard π€ Chen, Jing π€ Luo, Haibin π€ Yang, Yiming π€ Yang, Yifu π€ Zou, Jianping π€ Thiel, Volker π€ Chen, Kaixian π€ Shen, Jianhua π€ Shen, Xu π€ Jiang, Hualiang β° 2005 π Journal of Virology
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An overall picture of SARS coronavirus (SARS-CoV) genome-encoded major proteins: Structures, functions and drug development
π€ Chen, Shuai π€ Luo, Haibin π€ Chen, Lili π€ Chen, Jing π€ Shen, Jianhua π€ Zhu, Weiliang π€ Chen, Kaixian π€ Shen, Xu π€ Jiang, Hualiang β° 2006 π Current Pharmaceutical Design
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Residues on the dimer interface of SARS coronavirus 3C-like protease: Dimer stability characterization and enzyme catalytic activity analysis
π€ Chen, Shuai π€ Zhang, Jian π€ Hu, Tiancen π€ Chen, Kaixian π€ Jiang, Hualiang π€ Shen, Xu β° 2008 π Journal of Biochemistry
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[Exploration of omics mechanism and drug prediction of coronavirus-induced heart failure based on clinical bioinformatics].
π€ Chen, X M π€ Cao, F π€ Zhang, H M π€ Chen, H R π€ Zhang, J D π€ Zhi, P π€ Li, Z Y π€ Wang, Y X π€ Lu, X C β° 2020 π Zhonghua Xin Xue Guan Bing Za Zhi
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Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus
π€ Chou, Chi Yuan π€ Chien, Chia Hui π€ Han, Yu San π€ Prebanda, Mojca Trstenjak π€ Hsieh, Hsing Pang π€ Turk, Boris π€ Chang, Gu Gang π€ Chen, Xin β° 2008 π Biochemical Pharmacology
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Nucleocapsid protein recruitment to replication-transcription complexes plays a crucial role in coronaviral life cycle
π€ Cong, Yingying π€ Ulasli, Mustafa π€ Schepers, Hein π€ Mauthe, Mario π€ Vβkovski, Philip π€ Kriegenburg, Franziska π€ Thiel, Volker π€ de Haan, Cornelis A.M. π€ Reggiori, Fulvio β° 2020 π Journal of Virology
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Human coronaviruses: Viral and cellular factors involved in neuroinvasiveness and neuropathogenesis
π€ Desforges, Marc π€ Le Coupanec, Alain π€ Stodola, Jenny K. π€ Meessen-Pinard, Mathieu π€ Talbot, Pierre J. β° 2014 π Virus Research
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The cellular interactome of the coronavirus infectious bronchitis virus nucleocapsid protein and functional implications for virus biology
π€ Emmott, Edward π€ Munday, Diane π€ Bickerton, Erica π€ Britton, Paul π€ Rodgers, Mark A. π€ Whitehouse, Adrian π€ Zhou, En Min π€ Hiscox, Julian A. β° 2013 π Journal of Virology
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Proteolytic processing of polyproteins 1a and 1ab between non-structural proteins 10 and 11/12 of Coronavirus infectious bronchitis virus is dispensable for viral replication in cultured cells
π€ Fang, Shou Guo π€ Shen, Hongyuan π€ Wang, Jibin π€ Tay, Felicia P.L. π€ Liu, Ding Xiang β° 2008 π Virology
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Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2
π€ Glende, Joerg π€ Schwegmann-Wessels, Christel π€ Al-Falah, Marwan π€ Pfefferle, Susanne π€ Qu, Xiuxia π€ Deng, Hongkui π€ Drosten, Christian π€ Naim, Hassan Y. π€ Herrler, Georg β° 2008 π Virology
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Development of a red-shifted fluorescence-based assay for SARS-coronavirus 3CL protease: Identification of a novel class of anti-SARS agents from the tropical marine sponge Axinella corrugata
π€ Hamill, Pamela π€ Hudson, Derek π€ Kao, Richard Y. π€ Chow, Polly π€ Raj, Meera π€ Xu, Hongyan π€ Richer, Martin J. π€ Jean, FranΓ§ois β° 2006 π Biological Chemistry
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Targeting SARS-CoV-2: A Systematic Drug Repurposing Approach to Identify Promising Inhibitors Against 3C-like Proteinase and 2'-O-RiboseMethyltransferase.
π€ Khan, Rameez Jabeer π€ Jha, Rajat Kumar π€ Amera, GizachewMuluneh π€ Jain, Monika π€ Singh, Ekampreet π€ Pathak, Amita π€ Singh, Rashmi Prabha π€ Muthukumaran, Jayaraman π€ Singh, Amit Kumar β° 2020 π J Biomol Struct Dyn
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SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum
π€ Knoops, KΓ¨vin π€ Kikkert, Marjolein π€ Van Den Worm, Sjoerd H.E. π€ Zevenhoven-Dobbe, Jessika C. π€ Van Der Meer, Yvonne π€ Koster, Abraham J. π€ Mommaas, A. Mieke π€ Snijder, Eric J. β° 2008 π PLoS Biology
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Proteomic analysis of purified coronavirus infectious bronchitis virus particles
π€ Kong, Qingming π€ Xue, Chunyi π€ Ren, Xiangpeng π€ Zhang, Chengwen π€ Li, Linlin π€ Shu, Dingming π€ Bi, Yingzuo π€ Cao, Yongchang β° 2010 π Proteome Science
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The ADP-ribose-1β³-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses
π€ Kuri, Thomas π€ Eriksson, Klara K. π€ Putics, Akos π€ ZΓΌst, Roland π€ Snijder, Eric J. π€ Davidson, Andrew D. π€ Siddell, Stuart G. π€ Thiel, Volker π€ Ziebuhr, John π€ Weber, Friedemann β° 2011 π Journal of General Virology
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SARS virus: The beginning of the unraveling of a new coronavirus
π€ Lai, Michael M.C. β° 2003 π Journal of Biomedical Science
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Lipid rafts play an important role in the early stage of severe acute respiratory syndrome-coronavirus life cycle
π€ Li, Gui Mei π€ Li, Yong Gang π€ Yamate, Masanobu π€ Li, Shu Ming π€ Ikuta, Kazuyoshi β° 2007 π Microbes and Infection
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Characterization and inhibition of SARS-coronavirus main protease
π€ Liang, Po Huang β° 2006 π Current Topics in Medicinal Chemistry
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Expression of SARS-coronavirus envelope protein in Escherichia coli cells alters membrane permeability
π€ Liao, Y. π€ Lescar, J. π€ Tam, J. P. π€ Liu, D. X. β° 2004 π Biochemical and Biophysical Research Communications
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Overlapping and distinct molecular determinants dictating the antiviral activities of TRIM56 against flaviviruses and coronavirus
π€ Liu, Baoming π€ Li, Nan L. π€ Wang, Jie π€ Shi, Pei Yong π€ Wang, Tianyi π€ Miller, Mark A. π€ Li, Kui β° 2014 π Journal of Virology
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Leader sequences of coronavirus are altered during infection
π€ Liu, Li π€ Chen, Wei β° 2018 π Frontiers in Bioscience - Landmark
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Induction of Caspase-Dependent Apoptosis in Cultured Rat Oligodendrocytes by Murine Coronavirus Is Mediated during Cell Entry and Does Not Require Virus Replication
π€ Liu, Yin π€ Cai, Yingyun π€ Zhang, Xuming β° 2003 π Journal of Virology
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Importance of conserved cysteine residues in the coronavirus envelope protein
π€ Lopez, Lisa A. π€ Riffle, Ambere J. π€ Pike, Steven L. π€ Gardner, Douglas π€ Hogue, Brenda G. β° 2008 π Journal of Virology
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Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease
π€ Lu, I. Lin π€ Mahindroo, Neeraj π€ Liang, Po Huang π€ Peng, Yi Hui π€ Kuo, Chih Jung π€ Tsai, Keng Chang π€ Hsieh, Hsing Pang π€ Chao, Yu Sheng π€ Wu, Su Ying β° 2006 π Journal of Medicinal Chemistry
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Targeting Membrane-Bound Viral RNA Synthesis Reveals Potent Inhibition of Diverse Coronaviruses Including the Middle East Respiratory Syndrome Virus
π€ Lundin, Anna π€ Dijkman, Ronald π€ BergstrΓΆm, Tomas π€ Kann, Nina π€ Adamiak, Beata π€ Hannoun, Charles π€ Kindler, Eveline π€ JΓ³nsdΓ³ttir, Hulda R. π€ Muth, Doreen π€ Kint, Joeri π€ Forlenza, Maria π€ MΓΌller, Marcel A. π€ Drosten, Christian π€ Thiel, Volker π€ Trybala, Edward β° 2014 π PLoS Pathogens
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SARS coronavirus: Unusual lability of the nucleocapsid protein
π€ Mark, John π€ Li, Xuguang π€ Cyr, Terry π€ Fournier, Sylvie π€ Jaentschke, Bozena π€ Hefford, Mary Alice β° 2008 π Biochemical and Biophysical Research Communications
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Production of pseudotyped particles to study highly pathogenic coronaviruses in a biosafety level 2 setting
π€ Millet, Jean K. π€ Tang, Tiffany π€ Nathan, Lakshmi π€ Jaimes, Javier A. π€ Hsu, Hung Lun π€ Daniel, Susan π€ Whittaker, Gary R. β° 2019 π Journal of Visualized Experiments
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Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis
π€ Millet, Jean Kaoru π€ Whittaker, Gary R. β° 2015 π Virus Research
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Severe acute respiratory syndrome coronavirus Orf3a protein interacts with caveolin
π€ Padhan, Kartika π€ Tanwar, Charu π€ Hussain, Amjad π€ Hui, Pui Yan π€ Lee, Man Yan π€ Cheung, Chung Yan π€ Peiris, Joseph Sriyal Malik π€ Jameel, Shahid β° 2007 π Journal of General Virology
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Glycosylation of the viral attachment protein of avian coronavirus is essential for host cell and receptor binding
π€ Parsons, Lisa M. π€ Bouwman, Kim M. π€ Azurmendi, Hugo π€ De Vries, Robert P. π€ Cipollo, John F. π€ Verheije, Monique H. β° 2019 π Journal of Biological Chemistry
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Role of the lipid rafts in the life cycle of canine coronavirus
π€ Pratelli, Annamaria π€ Colao, Valeriana β° 2015 π Journal of General Virology
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Characteristics of the life cycle of porcine deltacoronavirus (PDCoV) in vitro: Replication kinetics, cellular ultrastructure and virion morphology, and evidence of inducing autophagy
π€ Qin, Pan π€ Du, En Zhong π€ Luo, Wen Ting π€ Yang, Yong Le π€ Zhang, Yu Qi π€ Wang, Bin π€ Huang, Yao Wei β° 2019 π Viruses
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The life cycle of SARS coronavirus in Vero E6 cells
π€ Qinfen, Zhang π€ Jinming, Cui π€ Xiaojun, Huang π€ Huanying, Zheng π€ Jicheng, Huang π€ Ling, Fang π€ Kunpeng, Li π€ Jingqiang, Zhang β° 2004 π Journal of Medical Virology
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The structure of the endoribonuclease XendoU: From small nucleolar RNA processing to severe acute respiratory syndrome coronavirus replication
π€ Renzi, Fabiana π€ Caffarelli, Elisa π€ Laneve, Pietro π€ Bozzoni, Irene π€ Brunori, Maurizio π€ Vallone, Beatrice β° 2006 π Proceedings of the National Academy of Sciences of the United States of America
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Severe acute respiratory syndrome coronavirus replication is severely impaired by MG132 due to proteasome-independent inhibition of M-calpain
π€ Schneider, Martha π€ Ackermann, Kerstin π€ Stuart, Melissa π€ Wex, Claudia π€ Protzer, Ulrike π€ SchΓ€tzl, Hermann M. π€ Gilch, Sabine β° 2012 π Journal of Virology
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Coronavirus envelope protein: Current knowledge
π€ Schoeman, Dewald π€ Fielding, Burtram C. β° 2019 π Virology Journal
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Saracatinib inhibits middle east respiratory syndrome-coronavirus replication in vitro
π€ Shin, Jin Soo π€ Jung, Eunhye π€ Kim, Meehyein π€ Baric, Ralph S. π€ Go, Yun Young β° 2018 π Viruses
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Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: Development of an ion-pair model for catalysis
π€ Solowiej, James π€ Thomson, James A. π€ Ryan, Kevin π€ Luo, Chun π€ He, Mingying π€ Lou, Jihong π€ Murray, Brion W. β° 2008 π Biochemistry
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Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4 - The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS)
π€ St. John, Sarah E. π€ Tomar, Sakshi π€ Stauffer, Shaun R. π€ Mesecar, Andrew D. β° 2015 π Bioorganic and Medicinal Chemistry
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Amiodarone alters late endosomes and inhibits SARS coronavirus infection at a post-endosomal level
π€ Stadler, Konrad π€ Ha, Huy Riem π€ Ciminale, Vincenzo π€ Spirli, Carlo π€ Saletti, Giulietta π€ Schiavon, Marco π€ Bruttomesso, Daniela π€ Bigler, Laurent π€ Follath, Ferenc π€ Pettenazzo, Andrea π€ Baritussio, Aldo β° 2008 π American Journal of Respiratory Cell and Molecular Biology
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The nucleocapsid protein of the SARS coronavirus is capable of self-association through a C-terminal 209 amino acid interaction domain
π€ Surjit, Milan π€ Liu, Boping π€ Kumar, Purnima π€ Chow, Vincent T.K. π€ Lal, Sunil K. β° 2004 π Biochemical and Biophysical Research Communications
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The cholesterol transport inhibitor U18666A inhibits type I feline coronavirus infection
π€ Takano, Tomomi π€ Endoh, Misaki π€ Fukatsu, Hiroaki π€ Sakurada, Haruko π€ Doki, Tomoyoshi π€ Hohdatsu, Tsutomu β° 2017 π Antiviral Research
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The severe acute respiratory syndrome (SARS) coronavirus NTPasefhelicase belongs to a distinct class of 5β² to 3β² viral helicases
π€ Tanner, Julian A. π€ Watt, Rory M. π€ Chai, Yu Bo π€ Lu, Lin Yu π€ Lin, Marie C. π€ Peiris, J. S.Malik π€ Poon, Leo L.M. π€ Kung, Hsiang Fu π€ Huang, Jian Dong β° 2003 π Journal of Biological Chemistry
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Establishment of a virulent full-length cDNA clone for type I feline coronavirus strain C3663
π€ Terada, Yutaka π€ Kuroda, Yudai π€ Morikawa, Shigeru π€ Matsuura, Yoshiharu π€ Maeda, Ken π€ Kamitani, Wataru β° 2019 π Journal of Virology
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Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin
π€ Ting, Du π€ Dong, Nan π€ Fang, Liurong π€ Lu, Jian π€ Bi, Jing π€ Xiao, Shaobo π€ Han, Heyou β° 2018 π ACS Applied Nano Materials
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SARS coronavirus anti-infectives.
π€ Tong, Tommy R. β° 2006 π Recent patents on anti-infective drug discovery
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Therapies for coronaviruses. Part 2: Inhibitors of intracellular life cycle
π€ Tong, Tommy R. β° 2009 π Expert Opinion on Therapeutic Patents
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The transmembrane oligomers of coronavirus protein E
π€ Torres, Jaume π€ Wang, Jifeng π€ Parthasarathy, Krupakar π€ Liu, Ding Xiang β° 2005 π Biophysical Journal
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Identification of host factors involved in coronavirus replication by quantitative proteomics analysis
π€ Vogels, Mijke W. π€ Van Balkom, Bas W.M. π€ Kaloyanova, Dora V. π€ Batenburg, Joseph J. π€ Heck, Albert J. π€ Helms, J. Bernd π€ Rottier, Peter J.M. π€ De Haan, Cornelis A.M. β° 2011 π Proteomics
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Glycogen synthase kinase-3 regulates the phosphorylation of severe acute respiratory syndrome coronavirus mucleocapsid protein and viral replication
π€ Wu, Chia Hsin π€ Yeh, Shiou Hwei π€ Tsay, Yeou Guang π€ Shieh, Ya Hsiung π€ Kao, Chuan Liang π€ Chen, Yen Shun π€ Wang, Sheng Han π€ Kuo, Ti Jung π€ Chen, Ding Shinn π€ Chen, Pei Jer β° 2009 π Journal of Biological Chemistry
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Severe acute respiratory syndrome coronavirus accessory protein 9b is a virion-associated protein
π€ Xu, Ke π€ Zheng, Bo Jian π€ Zeng, Rong π€ Lu, Wei π€ Lin, Yong Ping π€ Xue, Liang π€ Li, Li π€ Yang, Lei Lei π€ Xu, Chen π€ Dai, Jie π€ Wang, Fei π€ Li, Qing π€ Dong, Qing Xi π€ Yang, Rui Fu π€ Wu, Jia Rui π€ Sun, Bing β° 2009 π Virology
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Structure of the SARS coronavirus main proteinase as an active C 2 crystallographic dimer
π€ Xu, Ting π€ Ooi, Amy π€ Lee, Hooi Chen π€ Wilmouth, Rupert π€ Liu, Ding Xiang π€ Lescar, Julien β° 2005 π Acta Crystallographica Section F: Structural Biology and Crystallization Communications
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Phosphatidylinositol 4-kinase IIIΞ² is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry
π€ Yang, Ning π€ Ping, Ma π€ Lang, Jianshe π€ Zhang, Yanli π€ Deng, Jiejie π€ Ju, Xiangwu π€ Zhang, Gongyi π€ Jiang, Chengyu β° 2012 π Journal of Biological Chemistry
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Translational control of the subgenomic RNAs of severe acute respiratory syndrome coronavirus
π€ Yang, Yaling π€ Hussain, Snawar π€ Wang, Hao π€ Ke, Min π€ Guo, Deyin β° 2009 π Virus Genes
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The ubiquitin-proteasome system facilitates the transfer of murine coronavirus from endosome to cytoplasm during virus entry
π€ Yu, Guann Yi π€ Lai, Michael M.C. β° 2005 π Journal of Virology
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Structural and biochemical characterization of endoribonuclease nsp15 encoded by middle east respiratory syndrome coronavirus
π€ Zhang, Lianqi π€ Li, Lei π€ Yan, Liming π€ Ming, Zhenhua π€ Jia, Zhihui π€ Lou, Zhiyong π€ Rao, Zihe β° 2018 π Journal of Virology