π€ Baric, Ralph S.
Keywords
Articles (82)
-
Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses
π€ Agnihothram, Sudhakar π€ Gopal, Robin π€ Yount, Boyd L. π€ Donaldson, Eric F. π€ Menachery, Vineet D. π€ Graham, Rachel L. π€ Scobey, Trevor D. π€ Gralinski, Lisa E. π€ Denison, Mark R. π€ Zambon, Maria π€ Baric, Ralph S. β° 2014 π Journal of Infectious Diseases
-
A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant
π€ Agnihothram, Sudhakar π€ Yount Jr., Boyd L. π€ Donaldson, Eric F. π€ Huynh, Jeremy π€ Menachery, Vineet D. π€ Gralinski, Lisa E. π€ Graham, Rachel L. π€ Becker, Michelle M. π€ Tomar, Sakshi π€ Scobey, Trevor D. π€ Osswald, Heather L. π€ Whitmore, Alan π€ Gopal, Robin π€ Ghosh, Arun K. π€ Mesecar, Andrew π€ Zambon, Maria π€ Heise, Mark π€ Denison, Mark R. π€ Baric, Ralph S. β° 2014 π mBio
-
Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease
π€ Agostini, Maria L. π€ Andres, Erica L. π€ Sims, Amy C. π€ Graham, Rachel L. π€ Sheahan, Timothy P. π€ Lu, Xiaotao π€ Smith, Everett Clinton π€ Case, James Brett π€ Feng, Joy Y. π€ Jordan, Robert π€ Ray, Adrian S. π€ Cihlar, Tomas π€ Siegel, Dustin π€ Mackman, Richard L. π€ Clarke, Michael O. π€ Baric, Ralph S. π€ Denison, Mark R. β° 2018 π mBio
-
Small-Molecule Antiviral Ξ²-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance
π€ Agostini, Maria L. π€ Pruijssers, Andrea J. π€ Chappell, James D. π€ Gribble, Jennifer π€ Lu, Xiaotao π€ Andres, Erica L. π€ Bluemling, Gregory R. π€ Lockwood, Mark A. π€ Sheahan, Timothy P. π€ Sims, Amy C. π€ Natchus, Michael G. π€ Saindane, Manohar π€ Kolykhalov, Alexander A. π€ Painter, George R. π€ Baric, Ralph S. π€ Denison, Mark R. β° 2019 π Journal of virology
-
An experimental model for dilated cardiomyopathy after rabbit coronavirus infection
π€ Alexander, Lorraine K. π€ David Small, J. π€ Edwards, Suzanne π€ Baric, Ralph S. β° 1992 π Journal of Infectious Diseases
-
ECG changes after rabbit coronavirus infection
π€ Alexander, Lorraine K. π€ Keene, Bruce W. π€ Yount, Boyd L. π€ Geratz, Joachim Dieter π€ Small, J. David π€ Baric, Ralph S. β° 1999 π Journal of Electrocardiology
-
Establishing a genetic recombination map for murine coronavirus strain A59 complementation groups
π€ Baric, Ralph S. π€ Fu, Kaisong π€ Schaad, Mary C. π€ Stohlman, Stephen A. β° 1990 π Virology
-
Characterization of leader-related small RNAs in coronavirus-infected cells: Further evidence for leader-primed mechanism of transcription
π€ Baric, Ralph S. π€ Stohlman, Stephen A. π€ Razavi, Mahmood K. π€ Lai, Michael M.C. β° 1985 π Virus Research
-
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice
π€ Becker, Michelle M. π€ Graham, Rachel L. π€ Donaldson, Eric F. π€ Rockx, Barry π€ Sims, Amy C. π€ Sheahan, Timothy π€ Pickles, Raymond J. π€ Corti, Davide π€ Johnston, Robert E. π€ Baric, Ralph S. π€ Denison, Mark R. β° 2008 π Proceedings of the National Academy of Sciences of the United States of America
-
A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge
π€ Bolles, Meagan π€ Deming, Damon π€ Long, Kristin π€ Agnihothram, Sudhakar π€ Whitmore, Alan π€ Ferris, Martin π€ Funkhouser, William π€ Gralinski, Lisa π€ Totura, Allison π€ Heise, Mark π€ Baric, Ralph S. β° 2011 π Journal of Virology
-
Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase
π€ Brown, Ariane J. π€ Won, John J. π€ Graham, Rachel L. π€ Dinnon, Kenneth H. π€ Sims, Amy C. π€ Feng, Joy Y. π€ Cihlar, Tomas π€ Denison, Mark R. π€ Baric, Ralph S. π€ Sheahan, Timothy P. β° 2019 π Antiviral Research
-
Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures
π€ Chan, Renee W.Y. π€ Chan, Michael C.W. π€ Agnihothram, Sudhakar π€ Chan, Louisa L.Y. π€ Kuok, Denise I.T. π€ Fong, Joanne H.M. π€ Guan, Y. π€ Poon, Leo L.M. π€ Baric, Ralph S. π€ Nicholls, John M. π€ Peiris, J. S.Malik β° 2013 π Journal of Virology
-
Crystal structure of the receptor-binding domain from newly emerged middle east respiratory syndrome coronavirus
π€ Chen, Yaoqing π€ Rajashankar, Kanagalaghatta R. π€ Yang, Yang π€ Agnihothram, Sudhakar S. π€ Liu, Chang π€ Lin, Yi Lun π€ Baric, Ralph S. π€ Li, Fang β° 2013 π Journal of Virology
-
A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques
π€ Cockrell, Adam S. π€ Johnson, Joshua C. π€ Moore, Ian N. π€ Liu, David X. π€ Bock, Kevin W. π€ Douglas, Madeline G. π€ Graham, Rachel L. π€ Solomon, Jeffrey π€ Torzewski, Lisa π€ Bartos, Christopher π€ Hart, Randy π€ Baric, Ralph S. π€ Johnson, Reed F. β° 2018 π Scientific Reports
-
Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice
π€ Cockrell, Adam S. π€ Leist, Sarah R. π€ Douglas, Madeline G. π€ Baric, Ralph S. β° 2018 π Mammalian Genome
-
Mouse dipeptidyl peptidase 4 is not a functional receptor for middle east respiratory syndrome coronavirus infection
π€ Cockrell, Adam S. π€ Peck, Kayla M. π€ Yount, Boyd L. π€ Agnihothram, Sudhakar S. π€ Scobey, Trevor π€ Curnes, Nicole R. π€ Baric, Ralph S. π€ Heise, Mark T. β° 2014 π Journal of Virology
-
A mouse model for MERS coronavirus-induced acute respiratory distress syndrome
π€ Cockrell, Adam S. π€ Yount, Boyd L. π€ Scobey, Trevor π€ Jensen, Kara π€ Douglas, Madeline π€ Beall, Anne π€ Tang, Xian Chun π€ Marasco, Wayne A. π€ Heise, Mark T. π€ Baric, Ralph S. β° 2016 π Nature Microbiology
-
Antagonism of dsRNA-induced innate immune pathways by NS4a and NS4b accessory proteins during MERS coronavirus infection
π€ Comar, Courtney E. π€ Goldstein, Stephen A. π€ Li, Yize π€ Yount, Boyd π€ Baric, Ralph S. π€ Weiss, Susan R. β° 2019 π mBio
-
Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
π€ Corti, Davide π€ Zhao, Jincun π€ Pedotti, Mattia π€ Simonelli, Luca π€ Agnihothram, Sudhakar π€ Fett, Craig π€ Fernandez-Rodriguez, Blanca π€ Foglierini, Mathilde π€ Agatic, Gloria π€ Vanzetta, Fabrizia π€ Gopal, Robin π€ Langrish, Christopher J. π€ Barrett, Nicholas A. π€ Sallusto, Federica π€ Baric, Ralph S. π€ Varani, Luca π€ Zambon, Maria π€ Perlman, Stanley π€ Lanzavecchia, Antonio β° 2015 π Proceedings of the National Academy of Sciences of the United States of America
-
Reverse genetic analysis of the transcription regulatory sequence of the coronavirus transmissible gastroenteritis virus
π€ Curtis, Kristopher M. π€ Yount, Boyd π€ Sims, Amy C. π€ Baric, Ralph S. β° 2004 π Journal of Virology
-
Human coronaviruses and other respiratory infections in young adults on a university campus: Prevalence, symptoms, and shedding
π€ Davis, Brian M. π€ Foxman, Betsy π€ Monto, Arnold S. π€ Baric, Ralph S. π€ Martin, Emily T. π€ Uzicanin, Amra π€ Rainey, Jeanette J. π€ Aiello, Allison E. β° 2018 π Influenza and other Respiratory Viruses
-
A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses
π€ Deng, Xufang π€ Agnihothram, Sudhakar π€ Mielech, Anna M. π€ Nichols, Daniel B. π€ Wilson, Michael W. π€ St. John, Sarah E. π€ Larsen, Scott D. π€ Mesecar, Andrew D. π€ Lenschow, Deborah J. π€ Baric, Ralph S. π€ Baker, Susan C. β° 2014 π Journal of Virology
-
Coronaviruses: An RNA proofreading machine regulates replication fidelity and diversity
π€ Denison, Mark R. π€ Graham, Rachel L. π€ Donaldson, Eric F. π€ Eckerle, Lance D. π€ Baric, Ralph S. β° 2011 π RNA Biology
-
Systematic assembly of a full-length infectious clone of human coronavirus NL63
π€ Donaldson, Eric F. π€ Yount, Boyd π€ Sims, Amy C. π€ Burkett, Susan π€ Pickles, Raymond J. π€ Baric, Ralph S. β° 2008 π Journal of Virology
-
An experimental model for myocarditis and congestive heart failure after rabbit coronavirus infection
π€ Edwards, Suzanne π€ David Small, J. π€ Geratz, Joachim Dieter π€ Alexander, Lorraine K. π€ Baric, Ralph S. β° 1992 π Journal of Infectious Diseases
-
The open reading frame 3a protein of severe acute respiratory syndrome-associated coronavirus promotes membrane rearrangement and cell death
π€ Freundt, Eric C. π€ Yu, Li π€ Goldsmith, Cynthia S. π€ Welsh, Sarah π€ Cheng, Aaron π€ Yount, Boyd π€ Liu, Wei π€ Frieman, Matthew B. π€ Buchholz, Ursula J. π€ Screaton, Gavin R. π€ Lippincott-Schwartz, Jennifer π€ Zaki, Sherif R. π€ Xu, Xiao Ning π€ Baric, Ralph S. π€ Subbarao, Kanta π€ Lenardo, Michael J. β° 2010 π Journal of Virology
-
Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-ΞΊB signaling
π€ Frieman, Matthew π€ Ratia, Kiira π€ Johnston, Robert E. π€ Mesecar, Andrew D. π€ Baric, Ralph S. β° 2009 π Journal of Virology
-
Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease
π€ Frieman, Matthew π€ Yount, Boyd π€ Agnihothram, Sudhakar π€ Page, Carly π€ Donaldson, Eric π€ Roberts, Anjeanette π€ Vogel, Leatrice π€ Woodruff, Becky π€ Scorpio, Diana π€ Subbarao, Kanta π€ Baric, Ralph S. β° 2012 π Journal of Virology
-
Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane
π€ Frieman, Matthew π€ Yount, Boyd π€ Heise, Mark π€ Kopecky-Bromberg, Sarah A. π€ Palese, Peter π€ Baric, Ralph S. β° 2007 π Journal of Virology
-
Recombination, reservoirs, and the modular spike: Mechanisms of coronavirus cross-species transmission
π€ Graham, Rachel L. π€ Baric, Ralph S. β° 2010 π Journal of Virology
-
A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease
π€ Graham, Rachel L. π€ Becker, Michelle M. π€ Eckerle, Lance D. π€ Bolles, Meagan π€ Denison, Mark R. π€ Baric, Ralph S. β° 2012 π Nature Medicine
-
Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform
π€ Graham, Rachel L. π€ Deming, Damon J. π€ Deming, Meagan E. π€ Yount, Boyd L. π€ Baric, Ralph S. β° 2018 π Communications Biology
-
A decade after SARS: Strategies for controlling emerging coronaviruses
π€ Graham, Rachel L. π€ Donaldson, Eric F. π€ Baric, Ralph S. β° 2013 π Nature Reviews Microbiology
-
The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication
π€ Graham, Rachel L. π€ Sims, Amy C. π€ Brockway, Sarah M. π€ Baric, Ralph S. π€ Denison, Mark R. β° 2005 π Journal of Virology
-
Allelic variation in the toll-like receptor adaptor protein Ticam2 contributes to SARS-coronavirus pathogenesis in mice
π€ Gralinski, E. π€ Menachery, Vineet D. π€ Morgan, Andrew P. π€ Totura, Allison L. π€ Beall, Anne π€ Kocher, Jacob π€ Plante, Jessica π€ Harrison-Shostak, D. Corinne π€ SchΓ€fer, Alexandra π€ Villena, Fernando Pardo Manuel π€ Ferris, Martin T. π€ Baric, Ralph S. β° 2017 π G3: Genes, Genomes, Genetics
-
Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury
π€ Gralinski, Lisa E. π€ Bankhead III, Armand π€ Jeng, Sophia π€ Menachery, Vineet D. π€ Proll, Sean π€ Belisle, Sarah E. π€ Matzke, Melissa π€ Webb-Robertson, Bobbie Jo M. π€ Luna, Maria L. π€ Shukla, Anil K. π€ Ferris, Martin T. π€ Bolles, Meagan π€ Chang, Jean π€ Aicher, Lauri π€ Waters, Katrina M. π€ Smith, Richard D. π€ Metz, Thomas O. π€ Law, G. Lynn π€ Katze, Michael G. π€ McWeeney, Shannon π€ Baric, Ralph S. β° 2013 π mBio
-
Molecular pathology of emerging coronavirus infections
π€ Gralinski, Lisa E. π€ Baric, Ralph S. β° 2015 π Journal of Pathology
-
Complement activation contributes to severe acute respiratory syndrome coronavirus pathogenesis
π€ Gralinski, Lisa E. π€ Sheahan, Timothy P. π€ Morrison, Thomas E. π€ Menachery, Vineet D. π€ Jensen, Kara π€ Leist, Sarah R. π€ Whitmore, Alan π€ Heise, Mark T. π€ Baric, Ralph S. β° 2018 π mBio
-
Human coronavirus HKU1 spike protein uses O-acetylated sialic acid as an attachment receptor determinant and employs hemagglutinin-esterase protein as a receptor-destroying enzyme
π€ Huang, Xingchuan π€ Dong, Wenjuan π€ Milewska, Aleksandra π€ Golda, Anna π€ Qi, Yonghe π€ Zhu, Quan K. π€ Marasco, Wayne A. π€ Baric, Ralph S. π€ Sims, Amy C. π€ Pyrc, Krzysztof π€ Li, Wenhui π€ Sui, Jianhua β° 2015 π Journal of Virology
-
Evidence supporting a Zoonotic Origin of human coronavirus strain NL63
π€ Huynh, Jeremy π€ Li, Shimena π€ Yount, Boyd π€ Smith, Alexander π€ Sturges, Leslie π€ Olsen, John C. π€ Nagel, Juliet π€ Johnson, Joshua B. π€ Agnihothram, Sudhakar π€ Gates, J. Edward π€ Frieman, Matthew B. π€ Baric, Ralph S. π€ Donaldson, Eric F. β° 2012 π Journal of Virology
-
RNA dimerization plays a role in ribosomal frameshifting of the SARS coronavirus
π€ Ishimaru, Daniella π€ Plant, Ewan P. π€ Sims, Amy C. π€ Yount Jr., Boyd L. π€ Roth, Braden M. π€ Eldho, Nadukkudy V. π€ PΓ©rez-Alvarado, Gabriela C. π€ Armbruster, David W. π€ Baric, Ralph S. π€ Dinman, Jonathan D. π€ Taylor, Deborah R. π€ Hennig, Mirko β° 2013 π Nucleic Acids Research
-
Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus
π€ Josset, Laurence π€ Menachery, Vineet D. π€ Gralinski, Lisa E. π€ Agnihothram, Sudhakar π€ Sova, Pavel π€ Carter, Victoria S. π€ Yount, Boyd L. π€ Graham, Rachel L. π€ Baric, Ralph S. π€ Katzea, Michael G. β° 2013 π mBio
-
Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis
π€ Leist, Sarah R. π€ Jensen, Kara L. π€ Baric, Ralph S. π€ Sheahan, Timothy P. β° 2019 π PLoS ONE
-
mRNA display design of fibronectin-based intrabodies that detect and inhibit severe acute respiratory syndrome coronavirus nucleocapsid protein
π€ Liao, Hsiang I. π€ Olson, C. Anders π€ Hwang, Seungmin π€ Deng, Hongyu π€ Wong, Elaine π€ Baric, Ralph S. π€ Roberts, Richard W. π€ Sun, Ren β° 2009 π Journal of Biological Chemistry
-
The effect of inhibition of PP1 and TNFΞ± signaling on pathogenesis of SARS coronavirus
π€ McDermott, Jason E. π€ Mitchell, Hugh D. π€ Gralinski, Lisa E. π€ Eisfeld, Amie J. π€ Josset, Laurence π€ Bankhead, Armand π€ Neumann, Gabriele π€ Tilton, Susan C. π€ SchΓ€fer, Alexandra π€ Li, Chengjun π€ Fan, Shufang π€ McWeeney, Shannon π€ Baric, Ralph S. π€ Katze, Michael G. π€ Waters, Katrina M. β° 2016 π BMC Systems Biology
-
Coronavirus non-structural protein 16: Evasion, attenuation, and possible treatments
π€ Menachery, Vineet D. π€ Debbink, Kari π€ Baric, Ralph S. β° 2014 π Virus Research
-
Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses
π€ Menachery, Vineet D. π€ Eisfeld, Amie J. π€ SchΓ€fer, Alexandra π€ Josset, Laurence π€ Sims, Amy C. π€ Proll, Sean π€ Fan, Shufang π€ Li, Chengjun π€ Neumann, Gabriele π€ Tilton, Susan C. π€ Chang, Jean π€ Gralinski, Lisa E. π€ Long, Casey π€ Green, Richard π€ Williams, Christopher M. π€ Weiss, Jeffrey π€ Matzke, Melissa M. π€ Webb-Robertson, Bobbie Jo π€ Schepmoes, Athena A. π€ Shukla, Anil K. π€ Metz, Thomas O. π€ Smith, Richard D. π€ Waters, Katrina M. π€ Katze, Michael G. π€ Kawaoka, Yoshihiro π€ Baric, Ralph S. β° 2014 π mBio
-
Jumping speciesβa mechanism for coronavirus persistence and survival
π€ Menachery, Vineet D. π€ Graham, Rachel L. π€ Baric, Ralph S. β° 2017 π Current Opinion in Virology
-
Middle East respiratory syndrome coronavirus nonstructural protein 16 is necessary for interferon resistance and viral pathogenesis
π€ Menachery, Vineet D. π€ Gralinski, Lisa E. π€ Mitchell, Hugh D. π€ Dinnon, Kenneth H. π€ Leist, Sarah R. π€ Yount, Boyd L. π€ Graham, Rachel L. π€ McAnarney, Eileen T. π€ Stratton, Kelly G. π€ Cockrell, Adam S. π€ Debbink, Kari π€ Sims, Amy C. π€ Waters, Katrina M. π€ Baric, Ralph S. β° 2017 π mSphere
-
Combination attenuation offers strategy for live attenuated coronavirus vaccines
π€ Menachery, Vineet D. π€ Gralinski, Lisa E. π€ Mitchell, Hugh D. π€ Dinnon, Kenneth H. π€ Leist, Sarah R. π€ Yount, Boyd L. π€ McAnarney, Eileen T. π€ Graham, Rachel L. π€ Waters, Katrina M. π€ Baric, Ralph S. β° 2018 π Journal of Virology
-
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
π€ Menachery, Vineet D. π€ Yount, Boyd L. π€ Debbink, Kari π€ Agnihothram, Sudhakar π€ Gralinski, Lisa E. π€ Plante, Jessica A. π€ Graham, Rachel L. π€ Scobey, Trevor π€ Ge, Xing Yi π€ Donaldson, Eric F. π€ Randell, Scott H. π€ Lanzavecchia, Antonio π€ Marasco, Wayne A. π€ Shi, Zhengli Li π€ Baric, Ralph S. β° 2015 π Nature Medicine
-
Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity
π€ Menachery, Vineet D. π€ Yount, Boyd L. π€ Josset, Laurence π€ Gralinski, Lisa E. π€ Scobey, Trevor π€ Agnihothram, Sudhakar π€ Katze, Michael G. π€ Baric, Ralph S. β° 2014 π Journal of Virology
-
Severe acute respiratory syndrome coronavirus nsp 9 dimerization is essential for efficient viral growth
π€ Miknis, Zachary J. π€ Donaldson, Eric F. π€ Umland, Timothy C. π€ Rimmer, Ryan A. π€ Baric, Ralph S. π€ Schultz, L. Wayne β° 2009 π Journal of Virology
-
The endonucleolytic RNA cleavage function of nsp1 of middle east respiratory syndrome coronavirus promotes the production of infectious virus particles in specific human cell lines
π€ Nakagawa, Keisuke π€ Narayanan, Krishna π€ Wada, Masami π€ Popov, Vsevolod L. π€ Cajimat, Maria π€ Baric, Ralph S. π€ Makino, Shinji β° 2018 π Journal of Virology
-
Coronavirus Host Range Expansion and Middle East Respiratory Syndrome Coronavirus Emergence: Biochemical Mechanisms and Evolutionary Perspectives
π€ Peck, Kayla M. π€ Burch, Christina L. π€ Heise, Mark T. π€ Baric, Ralph S. β° 2015 π Annual Review of Virology
-
Glycosylation of mouse DPP4 plays a role in inhibiting middle east respiratory syndrome coronavirus infection
π€ Peck, Kayla M. π€ Cockrell, Adam S. π€ Yount, Boyd L. π€ Scobey, Trevor π€ Baric, Ralph S. π€ Heise, Mark T. β° 2015 π Journal of Virology
-
Permissivity of dipeptidyl peptidase 4 orthologs to Middle East respiratory syndrome coronavirus is governed by glycosylation and other complex determinants
π€ Peck, Kayla M. π€ Scobey, Trevor π€ Swanstrom, Jesica π€ Jensen, Kara L. π€ Burch, Christina L. π€ Baric, Ralph S. π€ Heise, Mark T. β° 2017 π Journal of Virology
-
Altering SARS coronavirus frameshift efficiency affects genomic and subgenomic RNA production
π€ Plant, Ewan P. π€ Sims, Amy C. π€ Baric, Ralph S. π€ Dinman, Jonathan D. π€ Taylor, Deborah R. β° 2013 π Viruses
-
Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus
π€ Rockx, Barry π€ Donaldson, Eric π€ Frieman, Matthew π€ Sheahan, Timothy π€ Corti, Davide π€ Lanzavecchia, Antonio π€ Baric, Ralph S. β° 2010 π Journal of Infectious Diseases
-
Epigenetic landscape during coronavirus infection
π€ SchΓ€fer, Alexandra π€ Baric, Ralph S. β° 2017 π Pathogens
-
Systems approaches to coronavirus pathogenesis
π€ SchΓ€fer, Alexandra π€ Baric, Ralph S. π€ Ferris, Martin T. β° 2014 π Current Opinion in Virology
-
Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus
π€ Scobey, Trevor π€ Yount, Boyd L. π€ Sims, Amy C. π€ Donaldson, Eric F. π€ Agnihothram, Sudhakar S. π€ Menachery, Vineet D. π€ Graham, Rachel L. π€ Swanstrom, Jesica π€ Bove, Peter F. π€ Kim, Jeeho D. π€ Grego, Sonia π€ Randell, Scott H. π€ Baric, Ralph S. β° 2013 π Proceedings of the National Academy of Sciences of the United States of America
-
Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus
π€ Sheahan, Timothy π€ Whitmore, Alan π€ Long, Kristin π€ Ferris, Martin π€ Rockx, Barry π€ Funkhouser, William π€ Donaldson, Eric π€ Gralinski, Lisa π€ Collier, Martha π€ Heise, Mark π€ Davis, Nancy π€ Johnston, Robert π€ Baric, Ralph S. β° 2011 π Journal of Virology
-
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
π€ Sheahan, Timothy P π€ Sims, Amy C π€ Zhou, Shuntai π€ Graham, Rachel L π€ Pruijssers, Andrea J π€ Agostini, Maria L π€ Leist, Sarah R π€ Schafer, Alexandra π€ Dinnon, Kenneth H 3rd π€ Stevens, Laura J π€ Chappell, James D π€ Lu, Xiaotao π€ Hughes, Tia M π€ George, Amelia S π€ Hill, Collin S π€ Montgomery, Stephanie A π€ Brown, Ariane J π€ Bluemling, Gregory R π€ Natchus, Michael G π€ Saindane, Manohar π€ Kolykhalov, Alexander A π€ Painter, George π€ Harcourt, Jennifer π€ Tamin, Azaibi π€ Thornburg, Natalie J π€ Swanstrom, Ronald π€ Denison, Mark R π€ Baric, Ralph S β° 2020 π Sci Transl Med
-
Saracatinib inhibits middle east respiratory syndrome-coronavirus replication in vitro
π€ Shin, Jin Soo π€ Jung, Eunhye π€ Kim, Meehyein π€ Baric, Ralph S. π€ Go, Yun Young β° 2018 π Viruses
-
Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: Role of ciliated cells in viral spread in the conducting airways of the lungs
π€ Sims, Amy C. π€ Baric, Ralph S. π€ Yount, Boyd π€ Burkett, Susan E. π€ Collins, Peter L. π€ Pickles, Raymond J. β° 2005 π Journal of Virology
-
Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice
π€ Sperry, Steven M. π€ Kazi, Lubna π€ Graham, Rachel L. π€ Baric, Ralph S. π€ Weiss, Susan R. π€ Denison, Mark R. β° 2005 π Journal of Virology
-
Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness
π€ Sui, Jianhua π€ Deming, Meagan π€ Rockx, Barry π€ Liddington, Robert C. π€ Zhu, Quan Karen π€ Baric, Ralph S. π€ Marasco, Wayne A. β° 2014 π Journal of Virology
-
Zn2+ inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture
π€ te Velthuis, Aartjan J.W. π€ van den Worml, Sjoerd H.E. π€ Sims, Amy C. π€ Baric, Ralph S. π€ Snijder, Eric J. π€ van Hemert, Martijn J. β° 2010 π PLoS Pathogens
-
SARS coronavirus pathogenesis: Host innate immune responses and viral antagonism of interferon
π€ Totura, Allison L. π€ Baric, Ralph S. β° 2012 π Current Opinion in Virology
-
Toll-like receptor 3 signaling via TRIF contributes to a protective innate immune response to severe acute respiratory syndrome coronavirus infection
π€ Totura, Allison L. π€ Whitmore, Alan π€ Agnihothram, Sudhakar π€ SchΓ€fer, Alexandra π€ Katze, Michael G. π€ Heise, Mark T. π€ Baric, Ralph S. β° 2015 π mBio
-
SARS-Like coronavirus WIV1-CoV does not replicate in Egyptian fruit bats (Rousettus aegyptiacus)
π€ van Doremalen, Neeltje π€ SchΓ€fer, Alexandra π€ Menachery, Vineet D. π€ Letko, Michael π€ Bushmaker, Trenton π€ Fischer, Robert J. π€ Figueroa, Dania M. π€ Hanley, Patrick W. π€ Saturday, Greg π€ Baric, Ralph S. π€ Munster, Vincent J. β° 2018 π Viruses
-
Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus.
π€ Wan, Yushun π€ Shang, Jian π€ Graham, Rachel π€ Baric, Ralph S π€ Li, Fang β° 2020 π J Virol
-
Severe acute respiratory syndrome coronavirus evades antiviral signaling: Role of nsp1 and rational design of an attenuated strain
π€ Wathelet, Marc G. π€ Orr, Melissa π€ Frieman, Matthew B. π€ Baric, Ralph S. β° 2007 π Journal of Virology
-
Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus
π€ Yang, Yang π€ Du, Lanying π€ Liu, Chang π€ Wang, Lili π€ Ma, Cuiqing π€ Tang, Jian π€ Baric, Ralph S. π€ Jiang, Shibo π€ Li, Fang β° 2014 π Proceedings of the National Academy of Sciences of the United States of America
-
Two mutations were critical for bat-to-human transmission of middle east respiratory syndrome coronavirus
π€ Yang, Yang π€ Liu, Chang π€ Du, Lanying π€ Jiang, Shibo π€ Shi, Zhengli π€ Baric, Ralph S. π€ Li, Fang β° 2015 π Journal of Virology
-
Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus
π€ Yount, Boyd π€ Curtis, Kristopher M. π€ Fritz, Elizabeth A. π€ Hensley, Lisa E. π€ Jahrling, Peter B. π€ Prentice, Erik π€ Denison, Mark R. π€ Geisbert, Thomas W. π€ Baric, Ralph S. β° 2003 π Proceedings of the National Academy of Sciences of the United States of America
-
Rewiring the severe acute respiratory syndrome coronavirus (SARS-CoV) transcription circuit: Engineering a recombination-resistant genome
π€ Yount, Boyd π€ Roberts, Rhonda S. π€ Lindesmith, Lisa π€ Baric, Ralph S. β° 2006 π Proceedings of the National Academy of Sciences of the United States of America
-
Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice
π€ Yount, Boyd π€ Roberts, Rhonda S. π€ Sims, Amy C. π€ Deming, Damon π€ Frieman, Matthew B. π€ Sparks, Jennifer π€ Denison, Mark R. π€ Davis, Nancy π€ Baric, Ralph S. β° 2005 π Journal of Virology
-
The nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU
π€ Zhang, Rong π€ Li, Yize π€ Cowley, Timothy J. π€ Steinbrenner, Adam D. π€ Phillips, Judith M. π€ Yount, Boyd L. π€ Baric, Ralph S. π€ Weiss, Susan R. β° 2015 π Journal of Virology
-
Airway Memory CD4+ T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses
π€ Zhao, Jincun π€ Zhao, Jingxian π€ Mangalam, Ashutosh K. π€ Channappanavar, Rudragouda π€ Fett, Craig π€ Meyerholz, David K. π€ Agnihothram, Sudhakar π€ Baric, Ralph S. π€ David, Chella S. π€ Perlman, Stanley β° 2016 π Immunity
-
Transcriptomic analysis reveals a mechanism for a prefibrotic phenotype in STAT1 knockout mice during severe acute respiratory syndrome coronavirus infection
π€ Zornetzer, Gregory A. π€ Frieman, Matthew B. π€ Rosenzweig, Elizabeth π€ Korth, Marcus J. π€ Page, Carly π€ Baric, Ralph S. π€ Katze, Michael G. β° 2010 π Journal of Virology