smith-everett-clinton

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🔗 severe acute (1373) 🔗 syndrome coronavirus (1074) 🔗 hepatitis virus (437) 🔗 amino acid (454) 🔗 murine hepatitis (71) 🔗 respiratory syndrome (2004) 🔗 acute respiratory (1734) 🔗 results indicate (178) 🔗 enzymatic activity (29) 🔗 endoplasmic reticulum (78) 🔗 nonstructural proteins (57) 🔗 mouse hepatitis (371) 🔗 coronavirus infection (270) 🔗 virus replication (219) 🔗 structural proteins (197) 🔗 packaging signal (16) 🔗 crystal structure (114) 🔗 viral replication (258) 🔗 spike protein (353) 🔗 host cell (262) 🔗 cell surface (110) 🔗 respiratory syndrome-associated (90) 🔗 data suggest (146) 🔗 results suggest (206) 🔗 syndrome-associated coronavirus (88) 🔗 determine whether (60) 🔗 human coronavirus (623)

Articles (7)

Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease
👤 Agostini, Maria L. 👤 Andres, Erica L. 👤 Sims, Amy C. 👤 Graham, Rachel L. 👤 Sheahan, Timothy P. 👤 Lu, Xiaotao 👤 Smith, Everett Clinton 👤 Case, James Brett 👤 Feng, Joy Y. 👤 Jordan, Robert 👤 Ray, Adrian S. 👤 Cihlar, Tomas 👤 Siegel, Dustin 👤 Mackman, Richard L. 👤 Clarke, Michael O. 👤 Baric, Ralph S. 👤 Denison, Mark R. ⏰ 2018 📚 mBio
In situ tagged nsp15 reveals interactions with coronavirus replication/transcription complex associated proteins
👤 Athmer, Jeremiah 👤 Fehr, Anthony R. 👤 Grunewald, Matthew 👤 Smith, Everett Clinton 👤 Denison, Mark R. 👤 Perlman, Stanley ⏰ 2017 📚 mBio
Coronaviruses induce entry-independent, Continuous macropinocytosis
👤 Freeman, Megan Culler 👤 Peek, Christopher T. 👤 Becker, Michelle M. 👤 Smith, Everett Clinton 👤 Denison, Mark R. ⏰ 2014 📚 mBio
Proofreading-deficient coronaviruses adapt for increased fitness over long-term passage without reversion of exoribonuclease-inactivating mutations
👤 Graepel, Kevin W. 👤 Lu, Xiaotao 👤 Case, James Brett 👤 Sexton, Nicole R. 👤 Smith, Everett Clinton 👤 Denisona, Mark R. ⏰ 2017 📚 mBio
Homology-based identification of a mutation in the coronavirus RNA-dependent RNA polymerase that confers resistance to multiple mutagens
👤 Sexton, Nicole R. 👤 Smith, Everett Clinton 👤 Blanc, Hervé 👤 Vignuzzi, Marco 👤 Peersen, Olve B. 👤 Denison, Mark R. ⏰ 2016 📚 Journal of Virology
Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics
👤 Smith, Everett Clinton 👤 Blanc, Hervé 👤 Vignuzzi, Marco 👤 Denison, Mark R. ⏰ 2013 📚 PLoS Pathogens
Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity
👤 Smith, Everett Clinton 👤 Case, James Brett 👤 Blanc, Hervé 👤 Isakov, Ofer 👤 Shomron, Noam 👤 Vignuzzi, Marco 👤 Denison, Mark R. ⏰ 2015 📚 Journal of Virology