π€ Graham, Rachel L.
Keywords
Articles (24)
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Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses
π€ Agnihothram, Sudhakar π€ Gopal, Robin π€ Yount, Boyd L. π€ Donaldson, Eric F. π€ Menachery, Vineet D. π€ Graham, Rachel L. π€ Scobey, Trevor D. π€ Gralinski, Lisa E. π€ Denison, Mark R. π€ Zambon, Maria π€ Baric, Ralph S. β° 2014 π Journal of Infectious Diseases
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A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant
π€ Agnihothram, Sudhakar π€ Yount Jr., Boyd L. π€ Donaldson, Eric F. π€ Huynh, Jeremy π€ Menachery, Vineet D. π€ Gralinski, Lisa E. π€ Graham, Rachel L. π€ Becker, Michelle M. π€ Tomar, Sakshi π€ Scobey, Trevor D. π€ Osswald, Heather L. π€ Whitmore, Alan π€ Gopal, Robin π€ Ghosh, Arun K. π€ Mesecar, Andrew π€ Zambon, Maria π€ Heise, Mark π€ Denison, Mark R. π€ Baric, Ralph S. β° 2014 π mBio
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Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease
π€ Agostini, Maria L. π€ Andres, Erica L. π€ Sims, Amy C. π€ Graham, Rachel L. π€ Sheahan, Timothy P. π€ Lu, Xiaotao π€ Smith, Everett Clinton π€ Case, James Brett π€ Feng, Joy Y. π€ Jordan, Robert π€ Ray, Adrian S. π€ Cihlar, Tomas π€ Siegel, Dustin π€ Mackman, Richard L. π€ Clarke, Michael O. π€ Baric, Ralph S. π€ Denison, Mark R. β° 2018 π mBio
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Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice
π€ Becker, Michelle M. π€ Graham, Rachel L. π€ Donaldson, Eric F. π€ Rockx, Barry π€ Sims, Amy C. π€ Sheahan, Timothy π€ Pickles, Raymond J. π€ Corti, Davide π€ Johnston, Robert E. π€ Baric, Ralph S. π€ Denison, Mark R. β° 2008 π Proceedings of the National Academy of Sciences of the United States of America
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Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase
π€ Brown, Ariane J. π€ Won, John J. π€ Graham, Rachel L. π€ Dinnon, Kenneth H. π€ Sims, Amy C. π€ Feng, Joy Y. π€ Cihlar, Tomas π€ Denison, Mark R. π€ Baric, Ralph S. π€ Sheahan, Timothy P. β° 2019 π Antiviral Research
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A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques
π€ Cockrell, Adam S. π€ Johnson, Joshua C. π€ Moore, Ian N. π€ Liu, David X. π€ Bock, Kevin W. π€ Douglas, Madeline G. π€ Graham, Rachel L. π€ Solomon, Jeffrey π€ Torzewski, Lisa π€ Bartos, Christopher π€ Hart, Randy π€ Baric, Ralph S. π€ Johnson, Reed F. β° 2018 π Scientific Reports
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Coronaviruses: An RNA proofreading machine regulates replication fidelity and diversity
π€ Denison, Mark R. π€ Graham, Rachel L. π€ Donaldson, Eric F. π€ Eckerle, Lance D. π€ Baric, Ralph S. β° 2011 π RNA Biology
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Coronavirus replicase-reporter fusions provide quantitative analysis of replication and replication complex formation
π€ Freeman, Megan Culler π€ Graham, Rachel L. π€ Lu, Xiaotao π€ Peek, Christopher T. π€ Denison, Mark R. β° 2014 π Journal of Virology
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Murine coronaviruses encoding nsp2 at different genomic loci have altered replication, protein expression, and localization
π€ Gadlage, Mark J. π€ Graham, Rachel L. π€ Denison, Mark R. β° 2008 π Journal of Virology
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Recombination, reservoirs, and the modular spike: Mechanisms of coronavirus cross-species transmission
π€ Graham, Rachel L. π€ Baric, Ralph S. β° 2010 π Journal of Virology
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A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease
π€ Graham, Rachel L. π€ Becker, Michelle M. π€ Eckerle, Lance D. π€ Bolles, Meagan π€ Denison, Mark R. π€ Baric, Ralph S. β° 2012 π Nature Medicine
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Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform
π€ Graham, Rachel L. π€ Deming, Damon J. π€ Deming, Meagan E. π€ Yount, Boyd L. π€ Baric, Ralph S. β° 2018 π Communications Biology
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A decade after SARS: Strategies for controlling emerging coronaviruses
π€ Graham, Rachel L. π€ Donaldson, Eric F. π€ Baric, Ralph S. β° 2013 π Nature Reviews Microbiology
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The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication
π€ Graham, Rachel L. π€ Sims, Amy C. π€ Brockway, Sarah M. π€ Baric, Ralph S. π€ Denison, Mark R. β° 2005 π Journal of Virology
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SARS coronavirus replicase proteins in pathogenesis
π€ Graham, Rachel L. π€ Sparks, Jennifer S. π€ Eckerle, Lance D. π€ Sims, Amy C. π€ Denison, Mark R. β° 2008 π Virus Research
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Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses
π€ Johnson, Bryan A. π€ Graham, Rachel L. π€ Menachery, Vineet D. β° 2018 π Virology
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Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus
π€ Josset, Laurence π€ Menachery, Vineet D. π€ Gralinski, Lisa E. π€ Agnihothram, Sudhakar π€ Sova, Pavel π€ Carter, Victoria S. π€ Yount, Boyd L. π€ Graham, Rachel L. π€ Baric, Ralph S. π€ Katzea, Michael G. β° 2013 π mBio
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Jumping speciesβa mechanism for coronavirus persistence and survival
π€ Menachery, Vineet D. π€ Graham, Rachel L. π€ Baric, Ralph S. β° 2017 π Current Opinion in Virology
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Middle East respiratory syndrome coronavirus nonstructural protein 16 is necessary for interferon resistance and viral pathogenesis
π€ Menachery, Vineet D. π€ Gralinski, Lisa E. π€ Mitchell, Hugh D. π€ Dinnon, Kenneth H. π€ Leist, Sarah R. π€ Yount, Boyd L. π€ Graham, Rachel L. π€ McAnarney, Eileen T. π€ Stratton, Kelly G. π€ Cockrell, Adam S. π€ Debbink, Kari π€ Sims, Amy C. π€ Waters, Katrina M. π€ Baric, Ralph S. β° 2017 π mSphere
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Combination attenuation offers strategy for live attenuated coronavirus vaccines
π€ Menachery, Vineet D. π€ Gralinski, Lisa E. π€ Mitchell, Hugh D. π€ Dinnon, Kenneth H. π€ Leist, Sarah R. π€ Yount, Boyd L. π€ McAnarney, Eileen T. π€ Graham, Rachel L. π€ Waters, Katrina M. π€ Baric, Ralph S. β° 2018 π Journal of Virology
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A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
π€ Menachery, Vineet D. π€ Yount, Boyd L. π€ Debbink, Kari π€ Agnihothram, Sudhakar π€ Gralinski, Lisa E. π€ Plante, Jessica A. π€ Graham, Rachel L. π€ Scobey, Trevor π€ Ge, Xing Yi π€ Donaldson, Eric F. π€ Randell, Scott H. π€ Lanzavecchia, Antonio π€ Marasco, Wayne A. π€ Shi, Zhengli Li π€ Baric, Ralph S. β° 2015 π Nature Medicine
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Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus
π€ Scobey, Trevor π€ Yount, Boyd L. π€ Sims, Amy C. π€ Donaldson, Eric F. π€ Agnihothram, Sudhakar S. π€ Menachery, Vineet D. π€ Graham, Rachel L. π€ Swanstrom, Jesica π€ Bove, Peter F. π€ Kim, Jeeho D. π€ Grego, Sonia π€ Randell, Scott H. π€ Baric, Ralph S. β° 2013 π Proceedings of the National Academy of Sciences of the United States of America
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An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
π€ Sheahan, Timothy P π€ Sims, Amy C π€ Zhou, Shuntai π€ Graham, Rachel L π€ Pruijssers, Andrea J π€ Agostini, Maria L π€ Leist, Sarah R π€ Schafer, Alexandra π€ Dinnon, Kenneth H 3rd π€ Stevens, Laura J π€ Chappell, James D π€ Lu, Xiaotao π€ Hughes, Tia M π€ George, Amelia S π€ Hill, Collin S π€ Montgomery, Stephanie A π€ Brown, Ariane J π€ Bluemling, Gregory R π€ Natchus, Michael G π€ Saindane, Manohar π€ Kolykhalov, Alexander A π€ Painter, George π€ Harcourt, Jennifer π€ Tamin, Azaibi π€ Thornburg, Natalie J π€ Swanstrom, Ronald π€ Denison, Mark R π€ Baric, Ralph S β° 2020 π Sci Transl Med
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Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice
π€ Sperry, Steven M. π€ Kazi, Lubna π€ Graham, Rachel L. π€ Baric, Ralph S. π€ Weiss, Susan R. π€ Denison, Mark R. β° 2005 π Journal of Virology