🔗 Nonstructural proteins

Articles (57)

• Genetic analysis of canine group 2 coronavirus in Korean dogs

  👤 An, Dong Jun 👤 Jeong, Wooseog 👤 Yoon, Sook Hee 👤 Jeoung, Hye Young 👤 Kim, Hyun Jeong 👤 Park, Bong Kyun ⏰ 2010 📚 Veterinary Microbiology

• Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles

  👤 Angelini, Megan M. 👤 Akhlaghpour, Marzieh 👤 Neuman, Benjamin W. 👤 Buchmeier, Michael J. ⏰ 2013 📚 mBio

• In situ tagged nsp15 reveals interactions with coronavirus replication/transcription complex associated proteins

  👤 Athmer, Jeremiah 👤 Fehr, Anthony R. 👤 Grunewald, Matthew 👤 Smith, Everett Clinton 👤 Denison, Mark R. 👤 Perlman, Stanley ⏰ 2017 📚 mBio

• Detection of nonstructural protein 6 in murine coronavirus-infected cells and analysis of the transmembrane topology by using bioinformatics and molecular approaches

  👤 Baliji, Surendranath 👤 Cammer, Stephen A. 👤 Sobral, Bruno 👤 Baker, Susan C. ⏰ 2009 📚 Journal of Virology

• RNA 3′-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex

  👤 Bouvet, Mickaël 👤 Imbert, Isabelle 👤 Subissi, Lorenzo 👤 Gluais, Laure 👤 Canard, Bruno 👤 Decroly, Etienne ⏰ 2012 📚 Proceedings of the National Academy of Sciences of the United States of America

• Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes

  👤 Bouvet, Mickaël 👤 Lugari, Adrien 👤 Posthuma, Clara C. 👤 Zevenhoven, Jessika C. 👤 Bernard, Stéphanie 👤 Betzi, Stéphane 👤 Imbert, Isabelle 👤 Canard, Bruno 👤 Guillemot, Jean Claude 👤 Lécine, Patrick 👤 Pfefferle, Susanne 👤 Drosten, Christian 👤 Snijder, Eric J. 👤 Decroly, Etienne 👤 Morelli, Xavier ⏰ 2014 📚 Journal of Biological Chemistry

• Recommendations of the coronavirus study group for the nomenclature of the structural proteins, mRNAs, and genes of coronaviruses

  👤 Cavanagh, D. 👤 Brian, D. A. 👤 Enjuanes, L. 👤 Holmes, K. V. 👤 Lai, M. M.C. 👤 Laude, H. 👤 Siddell, S. G. 👤 Spaan, W. 👤 Taguchi, F. 👤 Talbot, P. J. ⏰ 1990 📚 Virology

• Murine coronavirus nonstructural protein p28 arrests cell cycle in G 0/G1 phase

  👤 Chen, Chun Jen 👤 Sugiyama, Kazuo 👤 Kubo, Hideyuki 👤 Huang, Cheng 👤 Makino, Shinji ⏰ 2004 📚 Journal of Virology

• Expression, crystallization and preliminary crystallographic study of the functional mutant (N60K) of nonstructural protein 9 from Human coronavirus HKU1

  👤 Chen, Xia 👤 Tan, Yusheng 👤 Wang, Fenghua 👤 Wang, Jinshan 👤 Zhao, Qi 👤 Li, Shuang 👤 Fu, Sheng 👤 Chen, Cheng 👤 Yang, Haitao ⏰ 2014 📚 Acta Crystallographica Section F:Structural Biology Communications

• Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63

  👤 Chen, Zhongbin 👤 Wang, Yanhua 👤 Ratia, Kiira 👤 Mesecar, Andrew D. 👤 Wilkinson, Keith D. 👤 Baker, Susan C. ⏰ 2007 📚 Journal of Virology

• Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling

  👤 Cornillez-Ty, Cromwell T. 👤 Liao, Lujian 👤 Yates III, John R. 👤 Kuhn, Peter 👤 Buchmeier, Michael J. ⏰ 2009 📚 Journal of Virology

• Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate

  👤 Cottam, Eleanor M. 👤 Maier, Helena J. 👤 Manifava, Maria 👤 Vaux, Laura C. 👤 Chandra-Schoenfelder, Priya 👤 Gerner, Wilhelm 👤 Britton, Paul 👤 Ktistakis, Nick T. 👤 Wileman, Tom ⏰ 2011 📚 Autophagy

• Role of Nonstructural Proteins in the Pathogenesis of SARS-CoV-2.

  👤 da Silva, Severino Jefferson Ribeiro 👤 da Silva, Caroline Targino Alves 👤 Mendes, Renata Pessoa Germano 👤 Pena, Lindomar ⏰ 2020 📚 J Med Virol

• Coronaviruses: An RNA proofreading machine regulates replication fidelity and diversity

  👤 Denison, Mark R. 👤 Graham, Rachel L. 👤 Donaldson, Eric F. 👤 Eckerle, Lance D. 👤 Baric, Ralph S. ⏰ 2011 📚 RNA Biology

• A guideline for homology modeling of the proteins from newly discovered betacoronavirus, 2019 novel coronavirus (2019-nCoV).

  👤 Dong, Shengjie 👤 Sun, Jiachen 👤 Mao, Zhuo 👤 Wang, Lu 👤 Lu, Yi-Lin 👤 Li, Jiesen ⏰ 2020 📚 J Med Virol

• Nonstructural proteins NS7b and NS8 are likely to be phylogenetically associated with evolution of 2019-nCoV.

  👤 Fahmi, Muhamad 👤 Kubota, Yukihiko 👤 Ito, Masahiro ⏰ 2020 📚 Infect Genet Evol

• Functional and genetic studies of the substrate specificity of coronavirus infectious bronchitis virus 3C-like proteinase

  👤 Fang, Shouguo 👤 Shen, Hongyuan 👤 Wang, Jibin 👤 Tay, Felicia P.L. 👤 Liu, Ding Xiang ⏰ 2010 📚 Journal of Virology

• Extensive positive selection drives the evolution of nonstructural proteins in lineage C betacoronaviruses

  👤 Forni, Diego 👤 Cagliani, Rachele 👤 Mozzi, Alessandra 👤 Pozzoli, Uberto 👤 Al-Daghri, Nasser 👤 Clerici, Mario 👤 Sironi, Manuela ⏰ 2016 📚 Journal of Virology

• Exchange of the coronavirus replicase polyprotein cleavage sites alters protease specificity and processing

  👤 Gadlage, Mark J. 👤 Denison, Mark R. ⏰ 2010 📚 Journal of Virology

• Murine coronaviruses encoding nsp2 at different genomic loci have altered replication, protein expression, and localization

  👤 Gadlage, Mark J. 👤 Graham, Rachel L. 👤 Denison, Mark R. ⏰ 2008 📚 Journal of Virology

• The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus.

  👤 Gordon, Calvin J 👤 Tchesnokov, Egor P 👤 Feng, Joy Y 👤 Porter, Danielle P 👤 Gotte, Matthias ⏰ 2020 📚 J Biol Chem

• The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication

  👤 Graham, Rachel L. 👤 Sims, Amy C. 👤 Brockway, Sarah M. 👤 Baric, Ralph S. 👤 Denison, Mark R. ⏰ 2005 📚 Journal of Virology

• Biogenesis and dynamics of the coronavirus replicative structures

  👤 Hagemeijer, Marne C. 👤 Rottier, Peter J.M. 👤 de Haan, Cornelis A.M. ⏰ 2012 📚 Viruses

• Visualizing coronavirus RNA synthesis in time by using click chemistry

  👤 Hagemeijer, Marne C. 👤 Vonk, Annelotte M. 👤 Monastyrska, Iryna 👤 Rottier, Peter J.M. 👤 de Haan, Cornelis A.M. ⏰ 2012 📚 Journal of Virology

• Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity

  👤 Harcourt, Brian H. 👤 Jukneliene, Dalia 👤 Kanjanahaluethai, Amornrat 👤 Bechill, John 👤 Severson, Kari M. 👤 Smith, Catherine M. 👤 Rota, Paul A. 👤 Baker, Susan C. ⏰ 2004 📚 Journal of Virology

• Biologic, antigenic, and full-length genomic characterization of a bovine-like coronavirus isolated from a giraffe

  👤 Hasoksuz, Mustafa 👤 Alekseev, Konstantin 👤 Vlasova, Anastasia 👤 Zhang, Xinsheng 👤 Spiro, David 👤 Halpin, Rebecca 👤 Wang, Shiliang 👤 Ghedin, Elodie 👤 Saif, Linda J. ⏰ 2007 📚 Journal of Virology

• Leader-mrna junction sequences are unique for each subgenomic mrna species in the bovine coronavirus and remain so throughout persistent infection

  👤 Hofmann, Martin A. 👤 Chang, Ruey Yi 👤 Ku, Seulah 👤 Brian, David A. ⏰ 1993 📚 Virology

• The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding protein

  👤 Imbert, Isabelle 👤 Snijder, Eric J. 👤 Dimitrova, Maria 👤 Guillemot, Jean Claude 👤 Lécine, Patrick 👤 Canard, Bruno ⏰ 2008 📚 Virus Research

• Membrane binding proteins of coronaviruses

  👤 J Alsaadi, Entedar A. 👤 Jones, Ian M. ⏰ 2019 📚 Future Virology

• Membrane topology of murine coronavirus replicase nonstructural protein 3

  👤 Kanjanahaluethai, Amornrat 👤 Chen, Zhongbin 👤 Jukneliene, Dalia 👤 Baker, Susan C. ⏰ 2007 📚 Virology

• The nonstructural protein 8 (nsp8) of the SARS coronavirus interacts with its ORF6 accessory protein

  👤 Kumar, Purnima 👤 Gunalan, Vithiagaran 👤 Liu, Boping 👤 Chow, Vincent T.K. 👤 Druce, Julian 👤 Birch, Chris 👤 Catton, Mike 👤 Fielding, Burtram C. 👤 Tan, Yee Joo 👤 Lal, Sunil K. ⏰ 2007 📚 Virology

• Discovery of a novel coronavirus, China Rattus coronavirus HKU24, from norway rats supports the murine origin of Betacoronavirus 1 and has implications for the ancestor of Betacoronavirus lineage A

  👤 Lau, Susanna K.Y. 👤 Woo, Patrick C.Y. 👤 Li, Kenneth S.M. 👤 Tsang, Alan K.L. 👤 Fan, Rachel Y.Y. 👤 Luk, Hayes K.H. 👤 Cai, Jian Piao 👤 Chan, Kwok Hung 👤 Zheng, Bo Jian 👤 Wang, Ming 👤 Yuen, Kwok Yung ⏰ 2015 📚 Journal of Virology

• Complete genome analysis of canine respiratory coronavirus

  👤 Lim, Seong In 👤 Choi, Sarah 👤 Lim, Ji Ae 👤 Jeoung, Hye Young 👤 Song, Jae Young 👤 dela Pena, R. C. 👤 An, Dong Jun ⏰ 2013 📚 Genome Announcements

• Structure of the C-terminal domain of nsp4 from feline coronavirus

  👤 Manolaridis, Ioannis 👤 Wojdyla, Justyna A. 👤 Panjikar, Santosh 👤 Snijder, Eric J. 👤 Gorbalenya, Alexander E. 👤 Berglind, Hanna 👤 Nordlund, Pär 👤 Coutard, Bruno 👤 Tucker, Paul A. ⏰ 2009 📚 Acta Crystallographica Section D: Biological Crystallography

• Severe acute respiratory syndrome coronavirus nsp 9 dimerization is essential for efficient viral growth

  👤 Miknis, Zachary J. 👤 Donaldson, Eric F. 👤 Umland, Timothy C. 👤 Rimmer, Ryan A. 👤 Baric, Ralph S. 👤 Schultz, L. Wayne ⏰ 2009 📚 Journal of Virology

• Transmissible gastroenteritis coronavirus RNA-dependent RNA polymerase and nonstructural proteins 2, 3, and 8 are incorporated into viral particles

  👤 Nogales, Aitor 👤 Márquez-Jurado, Silvia 👤 Galán, Carmen 👤 Enjuanes, Luis 👤 Almazán, Fernando ⏰ 2012 📚 Journal of Virology

• Localization and membrane topology of coronavirus nonstructural protein 4: Involvement of the early secretory pathway in replication

  👤 Oostra, M. 👤 Te Lintelo, E. G. 👤 Deijs, M. 👤 Verheije, M. H. 👤 Rottier, P. J.M. 👤 De Haan, C. A.M. ⏰ 2007 📚 Journal of Virology

• Topology and membrane anchoring of the coronavirus replication complex: Not all hydrophobic domains of nsp3 and nsp6 are membrane spanning

  👤 Oostra, Monique 👤 Hagemeijer, Marne C. 👤 Van Gent, Michiel 👤 Bekker, Cornelis P.J. 👤 Te Lintelo, Eddie G. 👤 Rottier, Peter J.M. 👤 De Haan, Cornelis A.M. ⏰ 2008 📚 Journal of Virology

• Expression and cleavage of middle east respiratory syndrome coronavirus nsp3-4 polyprotein induce the formation of double-membrane vesicles that mimic those associated with coronaviral RNA replication

  👤 Oudshoorn, Diede 👤 Rijs, Kevin 👤 Limpens, Ronald W.A.L. 👤 Groen, Kevin 👤 Koster, Abraham J. 👤 Snijder, Eric J. 👤 Kikkert, Marjolein 👤 Bárcena, Montserrat ⏰ 2017 📚 mBio

• A severe acute respiratory syndrome-associated coronavirus-specific protein enhances virulence of an attenuated murine coronavirus

  👤 Pewe, Lecia 👤 Zhou, Haixia 👤 Netland, Jason 👤 Tangudu, Chandra 👤 Olivares, Heidi 👤 Shi, Lei 👤 Look, Dwight 👤 Gallagher, Thomas 👤 Perlman, Stanley ⏰ 2005 📚 Journal of Virology

• Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property

  👤 Piotrowski, Yvonne 👤 Hansen, Guido 👤 Boomaars-van Der Zanden, A. Linda 👤 Snijder, Eric J. 👤 Gorbalenya, Alexander E. 👤 Hilgenfeld, Rolf ⏰ 2009 📚 Protein Science

• Achieving a golden mean: Mechanisms by which coronaviruses ensure synthesis of the correct stoichiometric ratios of viral proteins

  👤 Plant, Ewan P. 👤 Rakauskaite, Rasa 👤 Taylor, Deborah R. 👤 Dinman, Jonathan D. ⏰ 2010 📚 Journal of Virology

• Drug targets for corona virus: A systematic review.

  👤 Prajapat, Manisha 👤 Sarma, Phulen 👤 Shekhar, Nishant 👤 Avti, Pramod 👤 Sinha, Shweta 👤 Kaur, Hardeep 👤 Kumar, Subodh 👤 Bhattacharyya, Anusuya 👤 Kumar, Harish 👤 Bansal, Seema 👤 Medhi, Bikash ⏰ 2020 📚 Indian J Pharmacol

• ADP-ribose-1″-monophosphatase: A conserved coronavirus enzyme that is dispensable for viral replication in tissue culture

  👤 Putics, Ákos 👤 Filipowicz, Witold 👤 Hall, Jonathan 👤 Gorbalenya, Alexander E. 👤 Ziebuhr, John ⏰ 2005 📚 Journal of Virology

• Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family

  👤 Ricagno, Stefano 👤 Egloff, Marie Pierre 👤 Ulferts, Rachel 👤 Coutard, Bruno 👤 Nurizzo, Didier 👤 Campanacci, Valérie 👤 Cambillau, Christian 👤 Ziebuhr, John 👤 Canard, Bruno ⏰ 2006 📚 Proceedings of the National Academy of Sciences of the United States of America

• Severe acute respiratory syndrome coronavirus nucleocapsid protein does not modulate transcription of the human FGL2 gene

  👤 Siu, Kam Leung 👤 Chan, Ching Ping 👤 Chan, Chris 👤 Zheng, Bo Jian 👤 Jin, Dong Yan ⏰ 2009 📚 Journal of General Virology

• Continuous and Discontinuous RNA Synthesis in Coronaviruses

  👤 Sola, Isabel 👤 Almazán, Fernando 👤 Zúñiga, Sonia 👤 Enjuanes, Luis ⏰ 2015 📚 Annual Review of Virology

• Dodecamer structure of severe acute respiratory syndrome coronavirus nonstructural protein nsp10

  👤 Su, Dan 👤 Lou, Zhiyong 👤 Sun, Fei 👤 Zhai, Yujia 👤 Yang, Haitao 👤 Zhang, Rongguang 👤 Joachimiak, Andrzej 👤 Zhang, Xuejun C. 👤 Bartlam, Mark 👤 Rao, Zihe ⏰ 2006 📚 Journal of Virology

• One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

  👤 Subissi, Lorenzo 👤 Posthuma, Clara C. 👤 Collet, Axelle 👤 Zevenhoven-Dobbe, Jessika C. 👤 Gorbalenya, Alexander E. 👤 Decroly, Etienne 👤 Snijder, Eric J. 👤 Canard, Bruno 👤 Imbert, Isabelle ⏰ 2014 📚 Proceedings of the National Academy of Sciences of the United States of America

• Recombination in avian gamma-coronavirus infectious bronchitis virus

  👤 Thor, Sharmi W. 👤 Hilt, Deborah A. 👤 Kissinger, Jessica C. 👤 Paterson, Andrew H. 👤 Jackwood, Mark W. ⏰ 2011 📚 Viruses

• Broad-spectrum coronavirus antiviral drug discovery

  👤 Totura, Allison L. 👤 Bavari, Sina ⏰ 2019 📚 Expert Opinion on Drug Discovery

• Expression, crystallization and preliminary crystallographic study of human coronavirus HKU1 nonstructural protein 9

  👤 Wang, Wei 👤 Wei, Lei 👤 Yang, Anqi 👤 He, Teng 👤 Yuen, K. Y. 👤 Chen, Cheng 👤 Rao, Zihe ⏰ 2009 📚 Acta Crystallographica Section F: Structural Biology and Crystallization Communications

• Inhibition of protein kinase R activation and upregulation of GADD34 expression play a synergistic role in facilitating coronavirus replication by maintaining de novo protein synthesis in virus-infected cells

  👤 Wang, Xiaoxing 👤 Liao, Ying 👤 Yap, Pei Ling 👤 Png, Kim J. 👤 Tam, James P. 👤 Liu, Ding Xiang ⏰ 2009 📚 Journal of Virology

• Crystal structures of two coronavirus ADP-ribose-1″-monophosphatases and their complexes with ADP-ribose: A systematic structural analysis of the viral ADRP domain

  👤 Xu, Yuanyuan 👤 Cong, Le 👤 Chen, Cheng 👤 Wei, Lei 👤 Zhao, Qi 👤 Xu, Xiaoling 👤 Ma, Yanlin 👤 Bartlam, Mark 👤 Rao, Zihe ⏰ 2009 📚 Journal of Virology

• Broad Cross-Species Infection of Cultured Cells by Bat HKU2-Related Swine Acute Diarrhea Syndrome Coronavirus and Identification of Its Replication in Murine Dendritic Cells In Vivo Highlight Its Potential for Diverse Interspecies Transmission

  👤 Yang, Yong Le 👤 Qin, Pan 👤 Wang, Bin 👤 Liu, Yan 👤 Xu, Guo Han 👤 Peng, Lei 👤 Zhou, Jiyong 👤 Zhu, Shu Jeffrey 👤 Huang, Yao Wei ⏰ 2019 📚 Journal of virology

• Structural and biochemical characterization of endoribonuclease nsp15 encoded by middle east respiratory syndrome coronavirus

  👤 Zhang, Lianqi 👤 Li, Lei 👤 Yan, Liming 👤 Ming, Zhenhua 👤 Jia, Zhihui 👤 Lou, Zhiyong 👤 Rao, Zihe ⏰ 2018 📚 Journal of Virology

• The nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU

  👤 Zhang, Rong 👤 Li, Yize 👤 Cowley, Timothy J. 👤 Steinbrenner, Adam D. 👤 Phillips, Judith M. 👤 Yount, Boyd L. 👤 Baric, Ralph S. 👤 Weiss, Susan R. ⏰ 2015 📚 Journal of Virology