kikkert-marjolein

Keywords

🔗 severe acute (1373) 🔗 syndrome coronavirus (1074) 🔗 papain-like protease (67) 🔗 innate immune (105) 🔗 immune response (314) 🔗 respiratory syndrome (2004) 🔗 acute respiratory (1734) 🔗 crystal structure (114) 🔗 previously reported (79) 🔗 secretory pathway (16) 🔗 virus replication (219) 🔗 life cycle (63) 🔗 endoplasmic reticulum (78) 🔗 host cell (262) 🔗 infected cells (307) 🔗 double-membrane vesicles (18) 🔗 viral replication (258) 🔗 nonstructural proteins (57) 🔗 transmembrane domain (51) 🔗 structural proteins (197) 🔗 membrane protein (93) 🔗 cells expressing (60) 🔗 hepatitis virus (437) 🔗 infectious peritonitis (181) 🔗 mouse hepatitis (371) 🔗 peritonitis virus (67) 🔗 feline infectious (145) 🔗 important role (140) 🔗 accessory proteins (53)

Articles (7)

Crystal structure of the middle east respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression
👤 Bailey-Elkin, Ben A. 👤 Knaap, Robert C.M. 👤 Johnson, Garrett G. 👤 Dalebout, Tim J. 👤 Ninaber, Dennis K. 👤 Van Kasteren, Puck B. 👤 Bredenbeek, Peter J. 👤 Snijder, Eric J. 👤 Kikkert, Marjolein 👤 Mark, Brian L. ⏰ 2014 📚 Journal of Biological Chemistry
A kinome-wide small interfering RNA screen identifies proviral and antiviral host factors in severe acute respiratory syndrome coronavirus replication, including double-stranded RNA-activated protein kinase and early secretory pathway proteins
👤 de Wilde, Adriaan H. 👤 Wannee, Kazimier F. 👤 Scholte, Florine E.M. 👤 Goeman, Jelle J. 👤 Ten Dijke, Peter 👤 Snijder, Eric J. 👤 Kikkert, Marjolein 👤 van Hemert, Martijn J. ⏰ 2015 📚 Journal of Virology
SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum
👤 Knoops, Kèvin 👤 Kikkert, Marjolein 👤 Van Den Worm, Sjoerd H.E. 👤 Zevenhoven-Dobbe, Jessika C. 👤 Van Der Meer, Yvonne 👤 Koster, Abraham J. 👤 Mommaas, A. Mieke 👤 Snijder, Eric J. ⏰ 2008 📚 PLoS Biology
Integrity of the early secretory pathway promotes, but is not required for, severe acute respiratory syndrome coronavirus RNA synthesis and virus-induced remodeling of endoplasmic reticulum membranes
👤 Knoops, Kévin 👤 Swett-Tapia, Cindy 👤 Van Den Worm, Sjoerd H.E. 👤 Te Velthuis, Aartjan J.W. 👤 Koster, Abraham J. 👤 Mommaas, A. Mieke 👤 Snijder, Eric J. 👤 Kikkert, Marjolein ⏰ 2010 📚 Journal of Virology
Expression and cleavage of middle east respiratory syndrome coronavirus nsp3-4 polyprotein induce the formation of double-membrane vesicles that mimic those associated with coronaviral RNA replication
👤 Oudshoorn, Diede 👤 Rijs, Kevin 👤 Limpens, Ronald W.A.L. 👤 Groen, Kevin 👤 Koster, Abraham J. 👤 Snijder, Eric J. 👤 Kikkert, Marjolein 👤 Bárcena, Montserrat ⏰ 2017 📚 mBio
The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle
👤 Raaben, Matthijs 👤 Posthuma, Clara C. 👤 Verheije, Monique H. 👤 Te Lintelo, Eddie G. 👤 Kikkert, Marjolein 👤 Drijfhout, Jan W. 👤 Snijder, Eric J. 👤 Rottier, Peter J.M. 👤 De Haan, Cornelis A.M. ⏰ 2010 📚 Journal of Virology
Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses
👤 Rabouw, Huib H. 👤 Langereis, Martijn A. 👤 Knaap, Robert C.M. 👤 Dalebout, Tim J. 👤 Canton, Javier 👤 Sola, Isabel 👤 Enjuanes, Luis 👤 Bredenbeek, Peter J. 👤 Kikkert, Marjolein 👤 de Groot, Raoul J. 👤 van Kuppeveld, Frank J.M. ⏰ 2016 📚 PLoS Pathogens