📚 PLoS Pathogens
Articles (32)
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Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner
👤 Burkard, Christine 👤 Verheije, Monique H. 👤 Wicht, Oliver 👤 van Kasteren, Sander I. 👤 van Kuppeveld, Frank J. 👤 Haagmans, Bart L. 👤 Pelkmans, Lucas 👤 Rottier, Peter J.M. 👤 Bosch, Berend Jan 👤 de Haan, Cornelis A.M. ⏰ 2014 📚 PLoS Pathogens
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Biochemical and structural insights into the mechanisms of sars coronavirus RNA ribose 2′-O-methylation by nsp16/nsp10 protein complex
👤 Chen, Yu 👤 Su, Ceyang 👤 Ke, Min 👤 Jin, Xu 👤 Xu, Lirong 👤 Zhang, Zhou 👤 Wu, Andong 👤 Sun, Ying 👤 Yang, Zhouning 👤 Tien, Po 👤 Ahola, Tero 👤 Liang, Yi 👤 Liu, Xinqi 👤 Guo, Deyin ⏰ 2011 📚 PLoS Pathogens
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Coronavirus gene 7 counteracts host defenses and modulates virus virulence
👤 Cruz, Jazmina L.G. 👤 Sola, Isabel 👤 Becares, Martina 👤 Alberca, Berta 👤 Plana, Joan 👤 Enjuanes, Luis 👤 Zuñiga, Sonia ⏰ 2011 📚 PLoS Pathogens
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Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex
👤 Decroly, Etienne 👤 Debarnot, Claire 👤 Ferron, François 👤 Bouvet, Mickael 👤 Coutard, Bruno 👤 Imbert, Isabelle 👤 Gluais, Laure 👤 Papageorgiou, Nicolas 👤 Sharff, Andrew 👤 Bricogne, Gérard 👤 Ortiz-Lombardia, Miguel 👤 Lescar, Julien 👤 Canard, Bruno ⏰ 2011 📚 PLoS Pathogens
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Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis
👤 DeDiego, Marta L. 👤 Nieto-Torres, Jose L. 👤 Jiménez-Guardeño, Jose M. 👤 Regla-Nava, Jose A. 👤 Álvarez, Enrique 👤 Oliveros, Juan Carlos 👤 Zhao, Jincun 👤 Fett, Craig 👤 Perlman, Stanley 👤 Enjuanes, Luis ⏰ 2011 📚 PLoS Pathogens
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The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases
👤 Earnest, James T. 👤 Hantak, Michael P. 👤 Li, Kun 👤 McCray, Paul B. 👤 Perlman, Stanley 👤 Gallagher, Tom ⏰ 2017 📚 PLoS Pathogens
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The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression
👤 Grunewald, Matthew E. 👤 Chen, Yating 👤 Kuny, Chad 👤 Maejima, Takashi 👤 Lease, Robert 👤 Ferraris, Dana 👤 Aikawa, Masanori 👤 Sullivan, Christopher S. 👤 Perlman, Stanley 👤 Fehr, Anthony R. ⏰ 2019 📚 PLoS Pathogens
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Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus
👤 Hu, Ben 👤 Zeng, Lei Ping 👤 Yang, Xing Lou 👤 Ge, Xing Yi 👤 Zhang, Wei 👤 Li, Bei 👤 Xie, Jia Zheng 👤 Shen, Xu Rui 👤 Zhang, Yun Zhi 👤 Wang, Ning 👤 Luo, Dong Sheng 👤 Zheng, Xiao Shuang 👤 Wang, Mei Niang 👤 Daszak, Peter 👤 Wang, Lin Fa 👤 Cui, Jie 👤 Shi, Zheng Li ⏰ 2017 📚 PLoS Pathogens
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SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: Viral mRNAs are resistant to nsp1-induced RNA cleavage
👤 Huang, Cheng 👤 Lokugamage, Kumari G. 👤 Rozovics, Janet M. 👤 Narayanan, Krishna 👤 Semler, Bert L. 👤 Makino, Shinji ⏰ 2011 📚 PLoS Pathogens
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Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus
👤 Huang, I. Chueh 👤 Bailey, Charles C. 👤 Weyer, Jessica L. 👤 Radoshitzky, Sheli R. 👤 Becker, Michelle M. 👤 Chiang, Jessica J. 👤 Brass, Abraham L. 👤 Ahmed, Asim A. 👤 Chi, Xiaoli 👤 Dong, Lian 👤 Longobardi, Lindsay E. 👤 Boltz, Dutch 👤 Kuhn, Jens H. 👤 Elledge, Stephen J. 👤 Bavari, Sina 👤 Denison, Mark R. 👤 Choe, Hyeryun 👤 Farzan, Michael ⏰ 2011 📚 PLoS Pathogens
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The PDZ-Binding Motif of Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Is a Determinant of Viral Pathogenesis
👤 Jimenez-Guardeño, Jose M. 👤 Nieto-Torres, Jose L. 👤 DeDiego, Marta L. 👤 Regla-Nava, Jose A. 👤 Fernandez-Delgado, Raul 👤 Castaño-Rodriguez, Carlos 👤 Enjuanes, Luis ⏰ 2014 📚 PLoS Pathogens
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Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor
👤 Kim, Yunjeong 👤 Liu, Hongwei 👤 Galasiti Kankanamalage, Anushka C. 👤 Weerasekara, Sahani 👤 Hua, Duy H. 👤 Groutas, William C. 👤 Chang, Kyeong Ok 👤 Pedersen, Niels C. ⏰ 2016 📚 PLoS Pathogens
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The murine coronavirus hemagglutinin-esterase receptor-binding site: A major shift in ligand specificity through modest changes in architecture
👤 Langereis, Martijn A. 👤 Zeng, Qinghong 👤 Heesters, Balthasar 👤 Huizinga, Eric G. 👤 de Groot, Raoul J. ⏰ 2012 📚 PLoS Pathogens
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Targeting Membrane-Bound Viral RNA Synthesis Reveals Potent Inhibition of Diverse Coronaviruses Including the Middle East Respiratory Syndrome Virus
👤 Lundin, Anna 👤 Dijkman, Ronald 👤 Bergström, Tomas 👤 Kann, Nina 👤 Adamiak, Beata 👤 Hannoun, Charles 👤 Kindler, Eveline 👤 Jónsdóttir, Hulda R. 👤 Muth, Doreen 👤 Kint, Joeri 👤 Forlenza, Maria 👤 Müller, Marcel A. 👤 Drosten, Christian 👤 Thiel, Volker 👤 Trybala, Edward ⏰ 2014 📚 PLoS Pathogens
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The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species
👤 Niemeyer, Daniela 👤 Mösbauer, Kirstin 👤 Klein, Eva M. 👤 Sieberg, Andrea 👤 Mettelman, Robert C. 👤 Mielech, Anna M. 👤 Dijkman, Ronald 👤 Baker, Susan C. 👤 Drosten, Christian 👤 Müller, Marcel A. ⏰ 2018 📚 PLoS Pathogens
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Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis
👤 Nieto-Torres, Jose L. 👤 DeDiego, Marta L. 👤 Verdiá-Báguena, Carmina 👤 Jimenez-Guardeño, Jose M. 👤 Regla-Nava, Jose A. 👤 Fernandez-Delgado, Raul 👤 Castaño-Rodriguez, Carlos 👤 Alcaraz, Antonio 👤 Torres, Jaume 👤 Aguilella, Vicente M. 👤 Enjuanes, Luis ⏰ 2014 📚 PLoS Pathogens
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Structure and inhibition of the SARS coronavirus envelope protein ion channel
👤 Pervushin, Konstantin 👤 Tan, Edward 👤 Parthasarathy, Krupakar 👤 Lin, Xin 👤 Jiang, Feng Li 👤 Yu, Dejie 👤 Vararattanavech, Ardcharaporn 👤 Tuck, Wah Soong 👤 Ding, Xiang Liu 👤 Torres, Jaume ⏰ 2009 📚 PLoS Pathogens
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The SARS-Coronavirus-host interactome: Identification of cyclophilins as target for pan-Coronavirus inhibitors
👤 Pfefferle, Susanne 👤 Schöpf, Julia 👤 Kögl, Manfred 👤 Friedel, Caroline C. 👤 Müller, Marcel A. 👤 Carbajo-Lozoya, Javier 👤 Stellberger, Thorsten 👤 von Dall'Armi, Ekatarina 👤 Herzog, Petra 👤 Kallies, Stefan 👤 Niemeyer, Daniela 👤 Ditt, Vanessa 👤 Kuri, Thomas 👤 Züst, Roland 👤 Pumpor, Ksenia 👤 Hilgenfeld, Rolf 👤 Schwarz, Frank 👤 Zimmer, Ralf 👤 Steffen, Imke 👤 Weber, Friedemann 👤 Thiel, Volker 👤 Herrler, Georg 👤 Thiel, Heinz Jürgen 👤 Schwegmann-Weßels, Christel 👤 Pöhlmann, Stefan 👤 Haas, Jürgen 👤 Drosten, Christian 👤 von Brunn, Albrecht ⏰ 2011 📚 PLoS Pathogens
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Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses
👤 Rabouw, Huib H. 👤 Langereis, Martijn A. 👤 Knaap, Robert C.M. 👤 Dalebout, Tim J. 👤 Canton, Javier 👤 Sola, Isabel 👤 Enjuanes, Luis 👤 Bredenbeek, Peter J. 👤 Kikkert, Marjolein 👤 de Groot, Raoul J. 👤 van Kuppeveld, Frank J.M. ⏰ 2016 📚 PLoS Pathogens
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Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies
👤 Reguera, Juan 👤 Santiago, César 👤 Mudgal, Gaurav 👤 Ordoño, Desiderio 👤 Enjuanes, Luis 👤 Casasnovas, José M. ⏰ 2012 📚 PLoS Pathogens
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A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice
👤 Roberts, Anjeanette 👤 Deming, Damon 👤 Paddock, Christopher D. 👤 Cheng, Aaron 👤 Yount, Boyd 👤 Vogel, Leatrice 👤 Herman, Brian D. 👤 Sheahan, Tim 👤 Heise, Mark 👤 Genrich, Gillian L. 👤 Zaki, Sherif R. 👤 Baric, Ralph 👤 Subbarao, Kanta ⏰ 2007 📚 PLoS Pathogens
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A single polar residue and distinct membrane topologies impact the function of the infectious bronchitis coronavirus E protein
👤 Ruch, Travis R. 👤 Machamer, Carolyn E. ⏰ 2012 📚 PLoS Pathogens
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Functional and genetic analysis of coronavirus replicase-transcriptase proteins
👤 Sawicki, Stanley G. 👤 Sawicki, Dorothea L. 👤 Younker, Diane 👤 Meyer, Yvonne 👤 Thiel, Volker 👤 Stokes, Helen 👤 Siddell, Stuart G. ⏰ 2005 📚 PLoS Pathogens
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Cryo-EM structure of infectious bronchitis coronavirus spike protein reveals structural and functional evolution of coronavirus spike proteins
👤 Shang, Jian 👤 Zheng, Yuan 👤 Yang, Yang 👤 Liu, Chang 👤 Geng, Qibin 👤 Luo, Chuming 👤 Zhang, Wei 👤 Li, Fang ⏰ 2018 📚 PLoS Pathogens
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Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics
👤 Smith, Everett Clinton 👤 Blanc, Hervé 👤 Vignuzzi, Marco 👤 Denison, Mark R. ⏰ 2013 📚 PLoS Pathogens
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Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2
👤 Song, Wenfei 👤 Gui, Miao 👤 Wang, Xinquan 👤 Xiang, Ye ⏰ 2018 📚 PLoS Pathogens
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Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway
👤 Sui, Jianhua 👤 Aird, Daniel R. 👤 Tamin, Azaibi 👤 Murakami, Akikazu 👤 Yan, Meiying 👤 Yammanuru, Anuradha 👤 Jing, Huaiqi 👤 Kan, Biao 👤 Liu, Xin 👤 Zhu, Quan 👤 Yuan, Qing An 👤 Adams, Gregory P. 👤 Bellini, William J. 👤 Xu, Jianguo 👤 Anderson, Larry J. 👤 Marasco, Wayne A. ⏰ 2008 📚 PLoS Pathogens
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The SARS-Unique Domain (SUD) of SARS coronavirus contains two macrodomains that bind G-quadruplexes
👤 Tan, Jinzhi 👤 Vonrhein, Clemens 👤 Smart, Oliver S. 👤 Bricogne, Gerard 👤 Bollati, Michela 👤 Kusov, Yuri 👤 Hansen, Guido 👤 Mesters, Jeroen R. 👤 Schmidt, Christian L. 👤 Hilgenfeld, Rolf ⏰ 2009 📚 PLoS Pathogens
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Zn2+ inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture
👤 te Velthuis, Aartjan J.W. 👤 van den Worml, Sjoerd H.E. 👤 Sims, Amy C. 👤 Baric, Ralph S. 👤 Snijder, Eric J. 👤 van Hemert, Martijn J. ⏰ 2010 📚 PLoS Pathogens
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SARS-coronavirus replication/transcription complexes are membrane-protected and need a host factor for activity in vitro
👤 Van Hemert, Martijn J. 👤 Van Den Worm, Sjoerd H.E. 👤 Knoops, Kèvin 👤 Mommaas, A. Mieke 👤 Gorbalenya, Alexander E. 👤 Snijder, Eric J. ⏰ 2008 📚 PLoS Pathogens
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Mouse hepatitis coronavirus RNA replication depends on GBF1-mediated ARF1 activation
👤 Verheije, Monique H. 👤 Raaben, Matthijs 👤 Mari, Muriel 👤 Te Lintelo, Eddie G. 👤 Reggiori, Fulvio 👤 Van Kuppeveld, Frank J.M. 👤 Rottier, Peter J.M. 👤 De Haan, Cornelis A.M. ⏰ 2008 📚 PLoS Pathogens
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Coronavirus non-structural protein 1 is a major pathogenicity factor: Implications for the rational design of coronavirus vaccines
👤 Züst, Roland 👤 Cervantes-Barragán, Luisa 👤 Kuri, Thomas 👤 Blakqori, Gjon 👤 Weber, Friedemann 👤 Ludewig, Burkhard 👤 Thiel, Volker ⏰ 2007 📚 PLoS Pathogens