groutas-william-c

Keywords

🔗 viral replication (258) 🔗 infectious peritonitis (181) 🔗 feline infectious (145) 🔗 enteric coronavirus (111) 🔗 coronavirus infection (270) 🔗 immune response (314) 🔗 virus replication (219) 🔗 immune responses (142) 🔗 results indicate (178) 🔗 gastroenteritis virus (188) 🔗 crystal structure (114) 🔗 previously reported (79) 🔗 transmissible gastroenteritis (226) 🔗 main protease (44) 🔗 papain-like protease (67) 🔗 peritonitis virus (67) 🔗 feline coronavirus (148) 🔗 cell culture (240) 🔗 hepatitis virus (437) 🔗 infectious disease (312) 🔗 fatality rate (123) 🔗 murine hepatitis (71) 🔗 results suggest (206) 🔗 infectious diseases (94) 🔗 resonance energy (16) 🔗 amino acid (454) 🔗 energy transfer (19)

Articles (7)

Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element
👤 Galasiti Kankanamalage, Anushka C. 👤 Kim, Yunjeong 👤 Damalanka, Vishnu C. 👤 Rathnayake, Athri D. 👤 Fehr, Anthony R. 👤 Mehzabeen, Nurjahan 👤 Battaile, Kevin P. 👤 Lovell, Scott 👤 Lushington, Gerald H. 👤 Perlman, Stanley 👤 Chang, Kyeong Ok 👤 Groutas, William C. ⏰ 2018 📚 European Journal of Medicinal Chemistry
Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor
👤 Kim, Yunjeong 👤 Liu, Hongwei 👤 Galasiti Kankanamalage, Anushka C. 👤 Weerasekara, Sahani 👤 Hua, Duy H. 👤 Groutas, William C. 👤 Chang, Kyeong Ok 👤 Pedersen, Niels C. ⏰ 2016 📚 PLoS Pathogens
Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses
👤 Kim, Yunjeong 👤 Lovell, Scott 👤 Tiew, Kok Chuan 👤 Mandadapu, Sivakoteswara Rao 👤 Alliston, Kevin R. 👤 Battaile, Kevin K. 👤 Groutas, William C. 👤 Chang, Kyeong Ok ⏰ 2012 📚 Journal of Virology
Potent inhibition of feline coronaviruses with peptidyl compounds targeting coronavirus 3C-like protease
👤 Kim, Yunjeong 👤 Mandadapu, Sivakoteswara Rao 👤 Groutas, William C. 👤 Chang, Kyeong Ok ⏰ 2013 📚 Antiviral Research
Broad-spectrum inhibitors against 3C-like proteases of feline coronaviruses and feline caliciviruses
👤 Kim, Yunjeong 👤 Shivanna, Vinay 👤 Narayanan, Sanjeev 👤 Prior, Allan M. 👤 Weerasekara, Sahani 👤 Hua, Duy H. 👤 Galasiti Kankanamalage, Anushka C. 👤 Groutas, William C. 👤 Chang, Kyeong Ok ⏰ 2015 📚 Journal of Virology
Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus
👤 Mandadapu, Sivakoteswara Rao 👤 Weerawarna, Pathum M. 👤 Prior, Allan M. 👤 Uy, Roxanne Adeline Z. 👤 Aravapalli, Sridhar 👤 Alliston, Kevin R. 👤 Lushington, Gerald H. 👤 Kim, Yunjeong 👤 Hua, Duy H. 👤 Chang, Kyeong Ok 👤 Groutas, William C. ⏰ 2013 📚 Bioorganic and Medicinal Chemistry Letters
Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor
👤 Perera, Krishani Dinali 👤 Rathnayake, Athri 👤 Liu, Hongwei 👤 Pedersen, Niels C. 👤 Groutas, William C. 👤 Chang, Kyeong Ok 👤 Kim, Yunjeong ⏰ 2019 📚 Veterinary Microbiology