Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses

© 2017 Elsevier Inc. Viral metagenomics, modeling of protein structure, and manipulation of viral genetics are key approaches that have laid the foundations of our understanding of coronavirus biology. In this review, we discuss the major advances each method has provided and discuss how future studies should leverage these strategies synergistically to answer novel questions.

keywords

author 👤 Johnson, Bryan A. 👤 Graham, Rachel L. 👤 Menachery, Vineet D.

year ⏰ 2018

journal 📚 Virology

issn 🗄 10960341 00426822

volume 517

number

page 30-37

doi 📄 10.1016/j.virol.2017.12.009 ⤴

citedbycount 1

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