🔗 Dipeptidyl peptidase

Articles (47)

• Generation of a transgenic mouse model of middle east respiratory syndrome coronavirus infection and disease

  👤 Agrawal, Anurodh Shankar 👤 Garron, Tania 👤 Tao, Xinrong 👤 Peng, Bi Hung 👤 Wakamiya, Maki 👤 Chan, Teh Sheng 👤 Couch, Robert B. 👤 Tseng, Chien Te K. ⏰ 2015 📚 Journal of Virology

• Elevated human dipeptidyl peptidase 4 expression reduces the susceptibility of hDPP4 transgenic mice to middle east respiratory syndrome coronavirus infection and disease

  👤 Algaissi, Abdullah 👤 Agrawal, Anurodh S. 👤 Han, Song 👤 Peng, Bi Hung 👤 Luo, Chuming 👤 Li, Fang 👤 Chan, Teh Sheng 👤 Couch, Robert B. 👤 Tseng, Chien Te K. ⏰ 2019 📚 Journal of Infectious Diseases

• A Comparative Review of Animal Models of Middle East Respiratory Syndrome Coronavirus Infection

  👤 Baseler, L. 👤 de Wit, E. 👤 Feldmann, H. ⏰ 2016 📚 Veterinary Pathology

• An acute immune response to middle east respiratory syndrome coronavirus replication contributes to viral pathogenicity

  👤 Baseler, Laura J. 👤 Falzarano, Darryl 👤 Scott, Dana P. 👤 Rosenke, Rebecca 👤 Thomas, Tina 👤 Munster, Vincent J. 👤 Feldmann, Heinz 👤 De Wit, Emmie ⏰ 2016 📚 American Journal of Pathology

• Membrane ectopeptidases targeted by human coronaviruses

  👤 Bosch, Berend Jan 👤 Smits, Saskia L. 👤 Haagmans, Bart L. ⏰ 2014 📚 Current Opinion in Virology

• Carcinoembryonic antigen-related cell adhesion molecule 5 is an important surface attachment factor that facilitates entry of middle east respiratory syndrome coronavirus

  👤 Chan, Che Man 👤 Chu, Hin 👤 Wang, Yixin 👤 Wong, Bosco Ho Yin 👤 Zhao, Xiaoyu 👤 Zhou, Jie 👤 Yang, Dong 👤 Leung, Sze Pui 👤 Chan, Jasper Fuk Woo 👤 Yeung, Man Lung 👤 Yan, Jinghua 👤 Lu, Guangwen 👤 Gao, George Fu 👤 Yuen, Kwok Yung ⏰ 2016 📚 Journal of Virology

• Protective effect of intranasal regimens containing peptidic middle east respiratory syndrome coronavirus fusion inhibitor against MERS-CoV infection

  👤 Channappanavar, Rudragouda 👤 Lu, Lu 👤 Xia, Shuai 👤 Du, Lanying 👤 Meyerholz, David K. 👤 Perlman, Stanley 👤 Jiang, Shibo ⏰ 2015 📚 Journal of Infectious Diseases

• Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells

  👤 Chu, Hin 👤 Chan, Che Man 👤 Zhang, Xi 👤 Wang, Yixin 👤 Yuan, Shuofeng 👤 Zhou, Jie 👤 Au-Yeung, Rex Kwok Him 👤 Sze, Kong Hung 👤 Yang, Dong 👤 Shuai, Huiping 👤 Hou, Yuxin 👤 Li, Cun 👤 Zhao, Xiaoyu 👤 Poon, Vincent Kwok Man 👤 Leung, Sze Pui 👤 Yeung, Man Lung 👤 Yan, Jinghua 👤 Lu, Guangwen 👤 Jin, Dong Yan 👤 Gao, George Fu 👤 Chan, Jasper Fuk Woo 👤 Yuen, Kwok Yung ⏰ 2018 📚 Journal of Biological Chemistry

• Mouse dipeptidyl peptidase 4 is not a functional receptor for middle east respiratory syndrome coronavirus infection

  👤 Cockrell, Adam S. 👤 Peck, Kayla M. 👤 Yount, Boyd L. 👤 Agnihothram, Sudhakar S. 👤 Scobey, Trevor 👤 Curnes, Nicole R. 👤 Baric, Ralph S. 👤 Heise, Mark T. ⏰ 2014 📚 Journal of Virology

• A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

  👤 Cockrell, Adam S. 👤 Yount, Boyd L. 👤 Scobey, Trevor 👤 Jensen, Kara 👤 Douglas, Madeline 👤 Beall, Anne 👤 Tang, Xian Chun 👤 Marasco, Wayne A. 👤 Heise, Mark T. 👤 Baric, Ralph S. ⏰ 2016 📚 Nature Microbiology

• Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus

  👤 Coleman, Christopher M. 👤 Matthews, Krystal L. 👤 Goicochea, Lindsay 👤 Frieman, Matthew B. ⏰ 2014 📚 Journal of General Virology

• Adaptive evolution of bat dipeptidyl peptidase 4 (dpp4): Implications for the origin and emergence of Middle East respiratory syndrome coronavirus

  👤 Cui, Jie 👤 Eden, John Sebastian 👤 Holmes, Edward C. 👤 Wang, Lin Fa ⏰ 2013 📚 Virology Journal

• A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in middle east respiratory syndrome coronavirus spike protein

  👤 Du, Lanying 👤 Zhao, Guangyu 👤 Yang, Yang 👤 Qiu, Hongjie 👤 Wang, Lili 👤 Kou, Zhihua 👤 Tao, Xinrong 👤 Yu, Hong 👤 Sun, Shihui 👤 Tseng, Chien Te K. 👤 Jiang, Shibo 👤 Li, Fang 👤 Zhou, Yusen ⏰ 2014 📚 Journal of Virology

• The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases

  👤 Earnest, James T. 👤 Hantak, Michael P. 👤 Li, Kun 👤 McCray, Paul B. 👤 Perlman, Stanley 👤 Gallagher, Tom ⏰ 2017 📚 PLoS Pathogens

• Experimental infection of dromedaries with Middle East respiratory syndrome-Coronavirus is accompanied by massive ciliary loss and depletion of the cell surface receptor dipeptidyl peptidase

  👤 Haverkamp, Ann Kathrin 👤 Lehmbecker, Annika 👤 Spitzbarth, Ingo 👤 Widagdo, Widagdo 👤 Haagmans, Bart L. 👤 Segalés, Joaquim 👤 Vergara-Alert, Julia 👤 Bensaid, Albert 👤 Van Den Brand, Judith M.A. 👤 Osterhaus, Albert D.M.E. 👤 Baumgärtner, Wolfgang ⏰ 2018 📚 Scientific Reports

• Acute respiratory infection in human dipeptidyl peptidase 4-transgenic mice infected with Middle East respiratory syndrome coronavirus

  👤 Iwata-Yoshikawa, Naoko 👤 Okamura, Tadashi 👤 Shimizu, Yukiko 👤 Kotani, Osamu 👤 Sato, Hironori 👤 Sekimukai, Hanako 👤 Fukushi, Shuetsu 👤 Suzuki, Tadaki 👤 Sato, Yuko 👤 Takeda, Makoto 👤 Tashiro, Masato 👤 Hasegawa, Hideki 👤 Nagata, Noriyo ⏰ 2019 📚 Journal of Virology

• Preparation of virus-like particle mimetic nanovesicles displaying the S protein of Middle East respiratory syndrome coronavirus using insect cells

  👤 Kato, Tatsuya 👤 Takami, Yoshihiro 👤 Kumar Deo, Vipin 👤 Park, Enoch Y. ⏰ 2019 📚 Journal of Biotechnology

• Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins

  👤 Lau, Susanna K.P. 👤 Fan, Rachel Y.Y. 👤 Luk, Hayes K.H. 👤 Zhu, Longchao 👤 Fung, Joshua 👤 Li, Kenneth S.M. 👤 Wong, Emily Y.M. 👤 Ahmed, Syed Shakeel 👤 Chan, Jasper F.W. 👤 Kok, Raven K.H. 👤 Chan, Kwok Hung 👤 Wernery, Ulrich 👤 Yuen, Kwok Yung 👤 Woo, Patrick C.Y. ⏰ 2018 📚 Emerging Microbes and Infections

• Identification of a novel betacoronavirus (merbecovirus) in amur hedgehogs from China

  👤 Lau, Susanna K.P. 👤 Luk, Hayes K.H. 👤 Wong, Antonio C.P. 👤 Fan, Rachel Y.Y. 👤 Lam, Carol S.F. 👤 Li, Kenneth S.M. 👤 Ahmed, Syed Shakeel 👤 Chow, Franklin W.N. 👤 Cai, Jian Piao 👤 Zhu, Xun 👤 Chan, Jasper F.W. 👤 Lau, Terrence C.K. 👤 Cao, Kaiyuan 👤 Li, Mengfeng 👤 Woo, Patrick C.Y. 👤 Yuen, Kwok Yung ⏰ 2019 📚 Viruses

• Receptor usage of a novel bat lineage C betacoronavirus reveals evolution of middle east respiratory syndrome-related coronavirus spike proteins for human dipeptidyl peptidase 4 binding

  👤 Lau, Susanna K.P. 👤 Zhang, Libiao 👤 Luk, Hayes K.H. 👤 Xiong, Lifeng 👤 Peng, Xingwen 👤 Li, Kenneth S.M. 👤 He, Xiangyang 👤 Zhao, Pyrear Su Hui 👤 Fan, Rachel Y.Y. 👤 Wong, Antonio C.P. 👤 Ahmed, Syed Shakeel 👤 Cai, Jian Piao 👤 Chan, Jasper F.W. 👤 Sun, Yinyan 👤 Jin, Dongyan 👤 Chen, Honglin 👤 Lau, Terrence C.K. 👤 Kok, Raven K.H. 👤 Li, Wenhui 👤 Yuen, Kwok Yung 👤 Woo, Patrick C.Y. ⏰ 2018 📚 Journal of Infectious Diseases

• Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis

  👤 Leist, Sarah R. 👤 Jensen, Kara L. 👤 Baric, Ralph S. 👤 Sheahan, Timothy P. ⏰ 2019 📚 PLoS ONE

• Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein

  👤 Li, Wentao 👤 Hulswit, Ruben J.G. 👤 Widjaja, Ivy 👤 Raj, V. Stalin 👤 McBride, Ryan 👤 Peng, Wenjie 👤 Widagdo, W. 👤 Tortorici, M. Alejandra 👤 Van Dieren, Brenda 👤 Lang, Yifei 👤 Van Lent, Jan W.M. 👤 Paulson, James C. 👤 De Haan, Cornelis A.M. 👤 De Groot, Raoul J. 👤 Van Kuppeveld, Frank J.M. 👤 Haagmans, Bart L. 👤 Bosch, Berend Jan ⏰ 2017 📚 Proceedings of the National Academy of Sciences of the United States of America

• Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26

  👤 Lu, Guangwen 👤 Hu, Yawei 👤 Wang, Qihui 👤 Qi, Jianxun 👤 Gao, Feng 👤 Li, Yan 👤 Zhang, Yanfang 👤 Zhang, Wei 👤 Yuan, Yuan 👤 Bao, Jinku 👤 Zhang, Buchang 👤 Shi, Yi 👤 Yan, Jinghua 👤 Gao, George F. ⏰ 2013 📚 Nature

• The receptor binding domain of the new middle east respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies

  👤 Mou, Huihui 👤 Raj, V. Stalin 👤 Van Kuppeveld, Frank J.M. 👤 Rottier, Peter J.M. 👤 Haagmans, Bart L. 👤 Bosch, Berend Jan ⏰ 2013 📚 Journal of Virology

• Middle east respiratory syndrome coronavirus (mers-cov): Infection, immunological response, and vaccine development

  👤 Mubarak, Ayman 👤 Alturaiki, Wael 👤 Hemida, Maged Gomaa ⏰ 2019 📚 Journal of Immunology Research

• Clinicopathologic, immunohistochemical, and ultrastructural findings of a fatal case of middle east respiratory syndrome coronavirus infection in the United Arab Emirates, April 2014

  👤 Ng, Dianna L. 👤 Al Hosani, Farida 👤 Keating, M. Kelly 👤 Gerber, Susan I. 👤 Jones, Tara L. 👤 Metcalfe, Maureen G. 👤 Tong, Suxiang 👤 Tao, Ying 👤 Alami, Negar N. 👤 Haynes, Lia M. 👤 Mutei, Mowafaq Ali 👤 Abdel-Wareth, Laila 👤 Uyeki, Timothy M. 👤 Swerdlow, David L. 👤 Barakat, Maha 👤 Zaki, Sherif R. ⏰ 2016 📚 American Journal of Pathology

• Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen

  👤 Nyon, Mun Peak 👤 Du, Lanying 👤 Tseng, Chien Te Kent 👤 Seid, Christopher A. 👤 Pollet, Jeroen 👤 Naceanceno, Kevin S. 👤 Agrawal, Anurodh 👤 Algaissi, Abdullah 👤 Peng, Bi Hung 👤 Tai, Wanbo 👤 Jiang, Shibo 👤 Bottazzi, Maria Elena 👤 Strych, Ulrich 👤 Hotez, Peter J. ⏰ 2018 📚 Vaccine

• Coronavirus Host Range Expansion and Middle East Respiratory Syndrome Coronavirus Emergence: Biochemical Mechanisms and Evolutionary Perspectives

  👤 Peck, Kayla M. 👤 Burch, Christina L. 👤 Heise, Mark T. 👤 Baric, Ralph S. ⏰ 2015 📚 Annual Review of Virology

• Glycosylation of mouse DPP4 plays a role in inhibiting middle east respiratory syndrome coronavirus infection

  👤 Peck, Kayla M. 👤 Cockrell, Adam S. 👤 Yount, Boyd L. 👤 Scobey, Trevor 👤 Baric, Ralph S. 👤 Heise, Mark T. ⏰ 2015 📚 Journal of Virology

• Permissivity of dipeptidyl peptidase 4 orthologs to Middle East respiratory syndrome coronavirus is governed by glycosylation and other complex determinants

  👤 Peck, Kayla M. 👤 Scobey, Trevor 👤 Swanstrom, Jesica 👤 Jensen, Kara L. 👤 Burch, Christina L. 👤 Baric, Ralph S. 👤 Heise, Mark T. ⏰ 2017 📚 Journal of Virology

• Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS)-coronavirus infection

  👤 Qiu, Hongjie 👤 Sun, Shihui 👤 Xiao, He 👤 Feng, Jiannan 👤 Guo, Yan 👤 Tai, Wanbo 👤 Wang, Yufei 👤 Du, Lanying 👤 Zhao, Guangyu 👤 Zhou, Yusen ⏰ 2016 📚 Antiviral Research

• Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

  👤 Raj, V. Stalin 👤 Mou, Huihui 👤 Smits, Saskia L. 👤 Dekkers, Dick H.W. 👤 Müller, Marcel A. 👤 Dijkman, Ronald 👤 Muth, Doreen 👤 Demmers, Jeroen A.A. 👤 Zaki, Ali 👤 Fouchier, Ron A.M. 👤 Thiel, Volker 👤 Drosten, Christian 👤 Rottier, Peter J.M. 👤 Osterhaus, Albert D.M.E. 👤 Bosch, Berend Jan 👤 Haagmans, Bart L. ⏰ 2013 📚 Nature

• High secretion of interferons by human plasmacytoid dendritic cells upon recognition of middle east respiratory syndrome coronavirus

  👤 Scheuplein, Vivian A. 👤 Seifried, Janna 👤 Malczyk, Anna H. 👤 Miller, Lilija 👤 Höcker, Lena 👤 Vergara-Alert, Júlia 👤 Dolnik, Olga 👤 Zielecki, Florian 👤 Becker, Björn 👤 Spreitzer, Ingo 👤 König, Renate 👤 Becker, Stephan 👤 Waibler, Zoe 👤 Mühlebach, Michael D. ⏰ 2015 📚 Journal of Virology

• Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus

  👤 Scobey, Trevor 👤 Yount, Boyd L. 👤 Sims, Amy C. 👤 Donaldson, Eric F. 👤 Agnihothram, Sudhakar S. 👤 Menachery, Vineet D. 👤 Graham, Rachel L. 👤 Swanstrom, Jesica 👤 Bove, Peter F. 👤 Kim, Jeeho D. 👤 Grego, Sonia 👤 Randell, Scott H. 👤 Baric, Ralph S. ⏰ 2013 📚 Proceedings of the National Academy of Sciences of the United States of America

• DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients

  👤 Seys, Leen J.M. 👤 Widagdo, W. 👤 Verhamme, Fien M. 👤 KleinJan, Alex 👤 Janssens, Wim 👤 Joos, Guy F. 👤 Bracke, Ken R. 👤 Haagmans, Bart L. 👤 Brusselle, Guy G. ⏰ 2018 📚 Clinical Infectious Diseases

• Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the middle East respiratory syndrome coronavirus

  👤 Stalin Raj, V. 👤 Smits, Saskia L. 👤 Provacia, Lisette B. 👤 van den Brand, Judith M.A. 👤 Wiersma, Lidewij 👤 Ouwendijk, Werner J.D. 👤 Bestebroer, Theo M. 👤 Spronken, Monique I. 👤 van Amerongen, Geert 👤 Rottier, Peter J.M. 👤 Fouchier, Ron A.M. 👤 Bosch, Berend Jan 👤 Osterhaus, Albert D.M.E. 👤 Haagmans, Bart L. ⏰ 2014 📚 Journal of Virology

• Emerging Developments on Pathogenicity, Molecular Virulence, Epidemiology and Clinical Symptoms of Current Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

  👤 Subbaram, Kannan 👤 Kannan, Hemalatha 👤 Khalil Gatasheh, Mansour ⏰ 2017 📚 HAYATI Journal of Biosciences

• Recombinant receptor-binding domains of multiple Middle East respiratory syndrome coronaviruses (MERS-CoVs) induce crossneutralizing antibodies against divergent human and camel MERS-CoVs and antibody escape mutants

  👤 Tai, Wanbo 👤 Wang, Yufei 👤 Fett, Craig A. 👤 Zhao, Guangyu 👤 Li, Fang 👤 Perlman, Stanley 👤 Jiang, Shibo 👤 Zhou, Yusen 👤 Du, Lanying ⏰ 2017 📚 Journal of Virology

• Co-localization of Middle East respiratory syndrome coronavirus (MERS-CoV) and dipeptidyl peptidase-4 in the respiratory tract and lymphoid tissues of pigs and llamas

  👤 Te, Nigeer 👤 Vergara-Alert, Júlia 👤 Lehmbecker, Annika 👤 Pérez, Mónica 👤 Haagmans, Bart L. 👤 Baumgärtner, Wolfgang 👤 Bensaid, Albert 👤 Segalés, Joaquim ⏰ 2019 📚 Transboundary and Emerging Diseases

• Host species restriction of middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4

  👤 van Doremalen, Neeltje 👤 Miazgowicz, Kerri L. 👤 Milne-Price, Shauna 👤 Bushmaker, Trenton 👤 Robertson, Shelly 👤 Scott, Dana 👤 Kinne, Joerg 👤 McLellan, Jason S. 👤 Zhu, Jiang 👤 Munster, Vincent J. ⏰ 2014 📚 Journal of Virology

• Mapping the specific amino acid residues that make hamster DPP4 functional as a receptor for Middle East respiratory syndrome coronavirus

  👤 van Doremalen, Neeltje 👤 Miazgowicz, Kerri L. 👤 Munster, Vincent J. ⏰ 2016 📚 Journal of Virology

• Animal models of Middle East respiratory syndrome coronavirus infection

  👤 Van Doremalen, Neeltje 👤 Munster, Vincent J. ⏰ 2015 📚 Antiviral Research

• Protective efficacy of recombinant modified vaccinia virus Ankara delivering Middle East respiratory syndrome coronavirus spike glycoprotein

  👤 Volz, Asisa 👤 Kupke, Alexandra 👤 Song, Fei 👤 Jany, Sylvia 👤 Fux, Robert 👤 Shams-Eldin, Hosam 👤 Schmidt, Jörg 👤 Becker, Christin 👤 Eickmann, Markus 👤 Becker, Stephan 👤 Sutter, Gerd ⏰ 2015 📚 Journal of Virology

• Tissue Distribution of the MERS-Coronavirus Receptor in Bats

  👤 Widagdo, W. 👤 Begeman, Lineke 👤 Schipper, Debby 👤 Van Run, Peter R. 👤 Cunningham, Andrew A. 👤 Kley, Nils 👤 Reusken, Chantal B. 👤 Haagmans, Bart L. 👤 Van Den Brand, Judith M.A. ⏰ 2017 📚 Scientific Reports

• Differential expression of the Middle East respiratory syndrome coronavirus receptor in the upper respiratory tracts of humans and dromedary camels

  👤 Widagdo, W. 👤 Raj, V. Stalin 👤 Schipper, Debby 👤 Kolijn, Kimberley 👤 Van Leenders, Geert J.L.H. 👤 Bosch, Berend J. 👤 Bensaid, Albert 👤 Segalés, Joaquim 👤 Baumgärtner, Wolfgang 👤 Osterhaus, Albert D.M.E. 👤 Koopmans, Marion P. 👤 Van Den Brand, Judith M.A. 👤 Haagmans, Bart L. ⏰ 2016 📚 Journal of Virology

• Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus

  👤 Yang, Yang 👤 Du, Lanying 👤 Liu, Chang 👤 Wang, Lili 👤 Ma, Cuiqing 👤 Tang, Jian 👤 Baric, Ralph S. 👤 Jiang, Shibo 👤 Li, Fang ⏰ 2014 📚 Proceedings of the National Academy of Sciences of the United States of America

• A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV

  👤 Zhao, Guangyu 👤 Du, Lanying 👤 Ma, Cuiqing 👤 Li, Ye 👤 Li, Lin 👤 Poon, Vincent Km 👤 Wang, Lili 👤 Yu, Fei 👤 Zheng, Bo Jian 👤 Jiang, Shibo 👤 Zhou, Yusen ⏰ 2013 📚 Virology Journal