leist-sarah-r

Keywords

🔗 highly pathogenic (100) 🔗 high mortality (78) 🔗 human coronavirus (623) 🔗 severe acute (1373) 🔗 syndrome coronavirus (1074) 🔗 distress syndrome (112) 🔗 weight loss (41) 🔗 coronavirus infection (270) 🔗 immune response (314) 🔗 virus replication (219) 🔗 data suggest (146) 🔗 respiratory syndrome (2004) 🔗 respiratory distress (139) 🔗 acute respiratory (1734) 🔗 viral load (91) 🔗 open access (18) 🔗 Animal models (72) 🔗 dipeptidyl peptidase (47) 🔗 flow cytometry (23) 🔗 reverse genetics (49) 🔗 highly conserved (80) 🔗 cell culture (240) 🔗 previously described (38) 🔗 results indicate (178) 🔗 causative agent (117) 🔗 host cell (262)

Articles (6)

Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice
👤 Cockrell, Adam S. 👤 Leist, Sarah R. 👤 Douglas, Madeline G. 👤 Baric, Ralph S. ⏰ 2018 📚 Mammalian Genome
Complement activation contributes to severe acute respiratory syndrome coronavirus pathogenesis
👤 Gralinski, Lisa E. 👤 Sheahan, Timothy P. 👤 Morrison, Thomas E. 👤 Menachery, Vineet D. 👤 Jensen, Kara 👤 Leist, Sarah R. 👤 Whitmore, Alan 👤 Heise, Mark T. 👤 Baric, Ralph S. ⏰ 2018 📚 mBio
Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis
👤 Leist, Sarah R. 👤 Jensen, Kara L. 👤 Baric, Ralph S. 👤 Sheahan, Timothy P. ⏰ 2019 📚 PLoS ONE
Middle East respiratory syndrome coronavirus nonstructural protein 16 is necessary for interferon resistance and viral pathogenesis
👤 Menachery, Vineet D. 👤 Gralinski, Lisa E. 👤 Mitchell, Hugh D. 👤 Dinnon, Kenneth H. 👤 Leist, Sarah R. 👤 Yount, Boyd L. 👤 Graham, Rachel L. 👤 McAnarney, Eileen T. 👤 Stratton, Kelly G. 👤 Cockrell, Adam S. 👤 Debbink, Kari 👤 Sims, Amy C. 👤 Waters, Katrina M. 👤 Baric, Ralph S. ⏰ 2017 📚 mSphere
Combination attenuation offers strategy for live attenuated coronavirus vaccines
👤 Menachery, Vineet D. 👤 Gralinski, Lisa E. 👤 Mitchell, Hugh D. 👤 Dinnon, Kenneth H. 👤 Leist, Sarah R. 👤 Yount, Boyd L. 👤 McAnarney, Eileen T. 👤 Graham, Rachel L. 👤 Waters, Katrina M. 👤 Baric, Ralph S. ⏰ 2018 📚 Journal of Virology
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
👤 Sheahan, Timothy P 👤 Sims, Amy C 👤 Zhou, Shuntai 👤 Graham, Rachel L 👤 Pruijssers, Andrea J 👤 Agostini, Maria L 👤 Leist, Sarah R 👤 Schafer, Alexandra 👤 Dinnon, Kenneth H 3rd 👤 Stevens, Laura J 👤 Chappell, James D 👤 Lu, Xiaotao 👤 Hughes, Tia M 👤 George, Amelia S 👤 Hill, Collin S 👤 Montgomery, Stephanie A 👤 Brown, Ariane J 👤 Bluemling, Gregory R 👤 Natchus, Michael G 👤 Saindane, Manohar 👤 Kolykhalov, Alexander A 👤 Painter, George 👤 Harcourt, Jennifer 👤 Tamin, Azaibi 👤 Thornburg, Natalie J 👤 Swanstrom, Ronald 👤 Denison, Mark R 👤 Baric, Ralph S ⏰ 2020 📚 Sci Transl Med