agostini-maria-l

Keywords

🔗 severe acute (1373) 🔗 syndrome coronavirus (1074) 🔗 hepatitis virus (437) 🔗 amino acid (454) 🔗 murine hepatitis (71) 🔗 respiratory syndrome (2004) 🔗 acute respiratory (1734) 🔗 results indicate (178) 🔗 viral replication (258) 🔗 causative agent (117) 🔗 weight loss (41) 🔗 host cell (262)

Articles (4)

Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease
👤 Agostini, Maria L. 👤 Andres, Erica L. 👤 Sims, Amy C. 👤 Graham, Rachel L. 👤 Sheahan, Timothy P. 👤 Lu, Xiaotao 👤 Smith, Everett Clinton 👤 Case, James Brett 👤 Feng, Joy Y. 👤 Jordan, Robert 👤 Ray, Adrian S. 👤 Cihlar, Tomas 👤 Siegel, Dustin 👤 Mackman, Richard L. 👤 Clarke, Michael O. 👤 Baric, Ralph S. 👤 Denison, Mark R. ⏰ 2018 📚 mBio
Small-Molecule Antiviral β-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance
👤 Agostini, Maria L. 👤 Pruijssers, Andrea J. 👤 Chappell, James D. 👤 Gribble, Jennifer 👤 Lu, Xiaotao 👤 Andres, Erica L. 👤 Bluemling, Gregory R. 👤 Lockwood, Mark A. 👤 Sheahan, Timothy P. 👤 Sims, Amy C. 👤 Natchus, Michael G. 👤 Saindane, Manohar 👤 Kolykhalov, Alexander A. 👤 Painter, George R. 👤 Baric, Ralph S. 👤 Denison, Mark R. ⏰ 2019 📚 Journal of virology
Fitness barriers limit reversion of a proofreading-deficient coronavirus
👤 Graepel, Kevin W. 👤 Agostini, Maria L. 👤 Lu, Xiaotao 👤 Sexton, Nicole R. 👤 Denisona, Mark R. ⏰ 2019 📚 Journal of Virology
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
👤 Sheahan, Timothy P 👤 Sims, Amy C 👤 Zhou, Shuntai 👤 Graham, Rachel L 👤 Pruijssers, Andrea J 👤 Agostini, Maria L 👤 Leist, Sarah R 👤 Schafer, Alexandra 👤 Dinnon, Kenneth H 3rd 👤 Stevens, Laura J 👤 Chappell, James D 👤 Lu, Xiaotao 👤 Hughes, Tia M 👤 George, Amelia S 👤 Hill, Collin S 👤 Montgomery, Stephanie A 👤 Brown, Ariane J 👤 Bluemling, Gregory R 👤 Natchus, Michael G 👤 Saindane, Manohar 👤 Kolykhalov, Alexander A 👤 Painter, George 👤 Harcourt, Jennifer 👤 Tamin, Azaibi 👤 Thornburg, Natalie J 👤 Swanstrom, Ronald 👤 Denison, Mark R 👤 Baric, Ralph S ⏰ 2020 📚 Sci Transl Med