👤 Case, James Brett

Keywords

Articles (4)

• Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease

  👤 Agostini, Maria L. 👤 Andres, Erica L. 👤 Sims, Amy C. 👤 Graham, Rachel L. 👤 Sheahan, Timothy P. 👤 Lu, Xiaotao 👤 Smith, Everett Clinton 👤 Case, James Brett 👤 Feng, Joy Y. 👤 Jordan, Robert 👤 Ray, Adrian S. 👤 Cihlar, Tomas 👤 Siegel, Dustin 👤 Mackman, Richard L. 👤 Clarke, Michael O. 👤 Baric, Ralph S. 👤 Denison, Mark R. ⏰ 2018 📚 mBio

• Mutagenesis of S-adenosyl-L-methionine-binding residues in coronavirus nsp14 N7-methyltransferase demonstrates differing requirements for genome translation and resistance to innate immunity

  👤 Case, James Brett 👤 Ashbrook, Alison W. 👤 Dermody, Terence S. 👤 Denisona, Mark R. ⏰ 2016 📚 Journal of Virology

• Proofreading-deficient coronaviruses adapt for increased fitness over long-term passage without reversion of exoribonuclease-inactivating mutations

  👤 Graepel, Kevin W. 👤 Lu, Xiaotao 👤 Case, James Brett 👤 Sexton, Nicole R. 👤 Smith, Everett Clinton 👤 Denisona, Mark R. ⏰ 2017 📚 mBio

• Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity

  👤 Smith, Everett Clinton 👤 Case, James Brett 👤 Blanc, Hervé 👤 Isakov, Ofer 👤 Shomron, Noam 👤 Vignuzzi, Marco 👤 Denison, Mark R. ⏰ 2015 📚 Journal of Virology