👤 Deng, Xufang

Keywords

Articles (12)

• Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the middle east respiratory syndrome coronavirus

  👤 Báez-Santos, Yahira M. 👤 Mielech, Anna M. 👤 Deng, Xufang 👤 Baker, Susan 👤 Mesecar, Andrew D. ⏰ 2014 📚 Journal of Virology

• A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses

  👤 Deng, Xufang 👤 Agnihothram, Sudhakar 👤 Mielech, Anna M. 👤 Nichols, Daniel B. 👤 Wilson, Michael W. 👤 St. John, Sarah E. 👤 Larsen, Scott D. 👤 Mesecar, Andrew D. 👤 Lenschow, Deborah J. 👤 Baric, Ralph S. 👤 Baker, Susan C. ⏰ 2014 📚 Journal of Virology

• An “Old” protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses

  👤 Deng, Xufang 👤 Baker, Susan C. ⏰ 2018 📚 Virology

• Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus.

  👤 Deng, Xufang 👤 Chen, Yafang 👤 Mielech, Anna M 👤 Hackbart, Matthew 👤 Kesely, Kristina R 👤 Mettelman, Robert C 👤 O'Brien, Amornrat 👤 Chapman, Mackenzie E 👤 Mesecar, Andrew D 👤 Baker, Susan C ⏰ 2020 📚 J Virol

• Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages

  👤 Deng, Xufang 👤 Hackbart, Matthew 👤 Mettelman, Robert C. 👤 O'Brien, Amornrat 👤 Mielech, Anna M. 👤 Yi, Guanghui 👤 Kao, C. Cheng 👤 Baker, Susan C. ⏰ 2017 📚 Proceedings of the National Academy of Sciences of the United States of America

• Analysis of coronavirus temperature-sensitive mutants reveals an interplay between the macrodomain and Papain-like protease impacting replication and pathogenesis

  👤 Deng, Xufang 👤 Mettelman, Robert C. 👤 O'Brien, Amornrat 👤 Thompson, John A. 👤 O'Brien, Timothy E. 👤 Baker, Susan C. ⏰ 2019 📚 Journal of Virology

• Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance

  👤 Deng, Xufang 👤 St John, Sarah E. 👤 Osswald, Heather L. 👤 O'Brien, Amornrat 👤 Banach, Bridget S. 👤 Sleeman, Katrina 👤 Ghosh, Arun K. 👤 Mesecar, Andrew D. 👤 Baker, Susan C. ⏰ 2014 📚 Journal of Virology

• Coronavirus endoribonuclease activity in porcine epidemic diarrhea virus suppresses type I and type III interferon responses

  👤 Deng, Xufang 👤 Van Geelen, Albert 👤 Buckley, Alexandra C. 👤 O’Brien, Amornrat 👤 Pillatzki, Angela 👤 Lager, Kelly M. 👤 Faaberg, Kay S. 👤 Baker, Susan C. ⏰ 2019 📚 Journal of Virology

• Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors.

  👤 Hackbart, Matthew 👤 Deng, Xufang 👤 Baker, Susan C ⏰ 2020 📚 Proc Natl Acad Sci U S A

• Assessing activity and inhibition of middle east respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors

  👤 Kilianski, Andy 👤 Mielech, Anna M. 👤 Deng, Xufang 👤 Baker, Susan C. ⏰ 2013 📚 Journal of Virology

• Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis

  👤 Mielech, Anna M. 👤 Deng, Xufang 👤 Chen, Yafang 👤 Kindler, Eveline 👤 Wheeler, Dorthea L. 👤 Mesecar, Andrew D. 👤 Thiel, Volker 👤 Perlman, Stanley 👤 Baker, Susan C. ⏰ 2015 📚 Journal of Virology

• Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages.

  👤 Volk, Aaron 👤 Hackbart, Matthew 👤 Deng, Xufang 👤 Cruz-Pulido, Yazmin 👤 O'Brien, Amornrat 👤 Baker, Susan C ⏰ 2020 📚 J Virol