๐ Viral entry
Articles (91)
-
Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms
๐ค Adedeji, Adeyemi O. ๐ค Severson, William ๐ค Jonsson, Colleen ๐ค Singh, Kamalendra ๐ค Weiss, Susan R. ๐ค Sarafianosa, Stefan G. โฐ 2013 ๐ Journal of Virology
-
Structural basis for human coronavirus attachment to sialic acid receptors
๐ค Alejandra Tortorici, M. ๐ค Walls, Alexandra C. ๐ค Lang, Yifei ๐ค Wang, Chunyan ๐ค Li, Zeshi ๐ค Koerhuis, Danielle ๐ค Boons, Geert Jan ๐ค Bosch, Berend Jan ๐ค Rey, Fรฉlix A. ๐ค de Groot, Raoul J. ๐ค Veesler, David โฐ 2019 ๐ Nature Structural and Molecular Biology
-
Pathogenesis of murine coronavirus in the central nervous system
๐ค Bender, Susan J. ๐ค Weiss, Susan R. โฐ 2010 ๐ Journal of Neuroimmune Pharmacology
-
Membrane ectopeptidases targeted by human coronaviruses
๐ค Bosch, Berend Jan ๐ค Smits, Saskia L. ๐ค Haagmans, Bart L. โฐ 2014 ๐ Current Opinion in Virology
-
Recommendations for coronavirus infection in rheumatic diseases treated with biologic therapy.
๐ค Ceribelli, Angela ๐ค Motta, Francesca ๐ค De Santis, Maria ๐ค Ansari, Aftab A ๐ค Ridgway, William M ๐ค Gershwin, M Eric ๐ค Selmi, Carlo โฐ 2020 ๐ J Autoimmun
-
Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection
๐ค Chan, Che Man ๐ค Lau, Susanna K.P. ๐ค Woo, Patrick C.Y. ๐ค Tse, Herman ๐ค Zheng, Bo Jian ๐ค Chen, Ling ๐ค Huang, Jian Dong ๐ค Yuen, Kwok Yung โฐ 2009 ๐ Journal of Virology
-
Functional characterization of heptad repeat 1 and 2 mutants of the spike protein of severe acute respiratory syndrome coronavirus
๐ค Chan, Woan Eng ๐ค Chuang, Chin Kai ๐ค Yeh, Shiou Hwei ๐ค Chang, Mau Sun ๐ค Chen, Steve S.L. โฐ 2006 ๐ Journal of Virology
-
Rhesus angiotensin converting enzyme 2 supports entry of severe acute respiratory syndrome coronavirus in Chinese macaques
๐ค Chen, Yunxin ๐ค Liu, Li ๐ค Wei, Qiang ๐ค Zhu, Hua ๐ค Jiang, Hong ๐ค Tu, Xinming ๐ค Qin, Chuan ๐ค Chen, Zhiwei โฐ 2008 ๐ Virology
-
Expression of SARS-coronavirus spike glycoprotein in Pichia pastoris
๐ค Chuck, Chi Pang ๐ค Wong, Chi Hang ๐ค Chow, Larry Ming Cheung ๐ค Fung, Kwok Pui ๐ค Waye, Mary Miu Yee ๐ค Tsui, Stephen Kwok Wing โฐ 2009 ๐ Virus Genes
-
Human monoclonal antibodies to SARS-coronavirus inhibit infection by different mechanisms
๐ค Coughlin, Melissa M. ๐ค Babcook, John ๐ค Prabhakar, Bellur S. โฐ 2009 ๐ Virology
-
The murine coronavirus nucleocapsid gene is a determinant of virulence
๐ค Cowley, Timothy J. ๐ค Long, Simon Y. ๐ค Weiss, Susan R. โฐ 2010 ๐ Journal of Virology
-
Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity
๐ค Du, Lanying ๐ค Kao, Richard Y. ๐ค Zhou, Yusen ๐ค He, Yuxian ๐ค Zhao, Guangyu ๐ค Wong, Charlotte ๐ค Jiang, Shibo ๐ค Yuen, Kwok Yung ๐ค Jin, Dong Yan ๐ค Zheng, Bo Jian โฐ 2007 ๐ Biochemical and Biophysical Research Communications
-
Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus (2019-nCoV) related coronavirus model.
๐ค Fan, Hua-Hao ๐ค Wang, Li-Qin ๐ค Liu, Wen-Li ๐ค An, Xiao-Ping ๐ค Liu, Zhen-Dong ๐ค He, Xiao-Qi ๐ค Song, Li-Hua ๐ค Tong, Yi-Gang โฐ 2020 ๐ Chin Med J (Engl)
-
Monitoring of s protein maturation in the endoplasmic reticulum by calnexin is important for the infectivity of severe acute respiratory syndrome coronavirus
๐ค Fukushi, Masaya ๐ค Yoshinaka, Yoshiyuki ๐ค Matsuoka, Yusuke ๐ค Hatakeyama, Seisuke ๐ค Ishizaka, Yukihito ๐ค Kirikae, Teruo ๐ค Sasazuki, Takehiko ๐ค Miyoshi-Akiyama, Tohru โฐ 2012 ๐ Journal of Virology
-
Inhibition of proprotein convertases abrogates processing of the middle eastern respiratory syndrome coronavirus spike protein in infected cells but does not reduce viral infectivity
๐ค Gierer, Stefanie ๐ค Mรผller, Marcel A. ๐ค Heurich, Adeline ๐ค Ritz, Daniel ๐ค Springstein, Benjamin L. ๐ค Karsten, Christina B. ๐ค Schendzielorz, Alexander ๐ค Gnirร, Kerstin ๐ค Drosten, Christian ๐ค Pรถhlmann, Stefan โฐ 2015 ๐ Journal of Infectious Diseases
-
Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response
๐ค Glowacka, Ilona ๐ค Bertram, Stephanie ๐ค Mรผller, Marcel A. ๐ค Allen, Paul ๐ค Soilleux, Elizabeth ๐ค Pfefferle, Susanne ๐ค Steffen, Imke ๐ค Tsegaye, Theodros Solomon ๐ค He, Yuxian ๐ค Gnirss, Kerstin ๐ค Niemeyer, Daniela ๐ค Schneider, Heike ๐ค Drosten, Christian ๐ค Pรถhlmann, Stefan โฐ 2011 ๐ Journal of Virology
-
Characterization of novel monoclonal antibodies against MERS-coronavirus spike protein
๐ค Goo, Junghyun ๐ค Jeong, Yuji ๐ค Park, Young Shin ๐ค Yang, Eunji ๐ค Jung, Dae Im ๐ค Rho, Semi ๐ค Park, Uni ๐ค Sung, Hyeyeong ๐ค Park, Pil Gu ๐ค Choi, Jung ah ๐ค Seo, Sang Hwan ๐ค Cho, Nam Hyuck ๐ค Lee, Hyeja ๐ค Lee, Jae Myun ๐ค Kim, Jae Ouk ๐ค Song, Manki โฐ 2020 ๐ Virus Research
-
Phylogenetic investigation of enteric bovine coronavirus in Ireland reveals partitioning between European and global strains
๐ค Gunn, L. ๐ค Collins, P. J. ๐ค O'connell, M. J. ๐ค O'shea, H. โฐ 2015 ๐ Irish Veterinary Journal
-
Solution structure of the severe acute respiratory syndrome-coronavirus heptad repeat 2 domain in the prefusion state
๐ค Hakansson-McReynolds, Susanna ๐ค Jiang, Shaokai ๐ค Rong, Lijun ๐ค Caffrey, Michael โฐ 2006 ๐ Journal of Biological Chemistry
-
TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein
๐ค Heurich, Adeline ๐ค Hofmann-Winkler, Heike ๐ค Gierer, Stefanie ๐ค Liepold, Thomas ๐ค Jahn, Olaf ๐ค Pรถhlmann, Stefan โฐ 2014 ๐ Journal of Virology
-
Cellular entry of the SARS coronavirus
๐ค Hofmann, Heike ๐ค Pรถhlmann, Stefan โฐ 2004 ๐ Trends in Microbiology
-
Immunological, structural, and preliminary X-ray diffraction characterizations of the fusion core of the SARS-coronavirus spike protein
๐ค Hsu, Chun Hua ๐ค Ko, Tzu Ping ๐ค Yu, Hui Ming ๐ค Tang, Tswen Kei ๐ค Chen, Shui Tsung ๐ค Wang, Andrew H.J. โฐ 2004 ๐ Biochemical and Biophysical Research Communications
-
Clathrin-dependent entry of severe acute respiratory syndrome coronavirus into target cells expressing ACE2 with the cytoplasmic tail deleted
๐ค Inoue, Yuuki ๐ค Tanaka, Nobuyuki ๐ค Tanaka, Yoshinori ๐ค Inoue, Shingo ๐ค Morita, Kouichi ๐ค Zhuang, Min ๐ค Hattori, Toshio ๐ค Sugamura, Kazuo โฐ 2007 ๐ Journal of Virology
-
Anti-severe acute respiratory syndrome coronavirus spike antibodies trigger infection of human immune cells via a pH- and cysteine protease-independent Fcฮณr pathway
๐ค Jaume, Martial ๐ค Yip, Ming S. ๐ค Cheung, Chung Y. ๐ค Leung, Hiu L. ๐ค Li, Ping H. ๐ค Kien, Francois ๐ค Dutry, Isabelle ๐ค Callendret, Benoรฎt ๐ค Escriou, Nicolas ๐ค Altmeyer, Ralf ๐ค Nal, Beatrice ๐ค Daรซron, Marc ๐ค Bruzzone, Roberto ๐ค Peiris, J. S.Malik โฐ 2011 ๐ Journal of Virology
-
Cholesterol is important for the entry process of porcine deltacoronavirus
๐ค Jeon, Ji Hyun ๐ค Lee, Changhee โฐ 2018 ๐ Archives of Virology
-
Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro
๐ค Kam, Yiu Wing ๐ค Okumura, Yuushi ๐ค Kido, Hiroshi ๐ค Ng, Lisa F.P. ๐ค Bruzzone, Roberto ๐ค Altmeyer, Ralf โฐ 2009 ๐ PLoS ONE
-
Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics
๐ค Kao, Richard Y. ๐ค Tsui, Wayne H.W. ๐ค Lee, Terri S.W. ๐ค Tanner, Julian A. ๐ค Watt, Rory M. ๐ค Huang, Jian Dong ๐ค Hu, Lihong ๐ค Chen, Guanhua ๐ค Chen, Zhiwei ๐ค Zhang, Linqi ๐ค He, Tian ๐ค Chan, Kwok Hung ๐ค Tse, Herman ๐ค To, Amanda P.C. ๐ค Ng, Louisa W.Y. ๐ค Wong, Bonnie C.W. ๐ค Tsoi, Hoi Wah ๐ค Yang, Dan ๐ค Ho, David D. ๐ค Yuen, Kwok Yung โฐ 2004 ๐ Chemistry and Biology
-
Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry
๐ค Kawase, Miyuki ๐ค Shirato, Kazuya ๐ค van der Hoek, Lia ๐ค Taguchi, Fumihiro ๐ค Matsuyama, Shutoku โฐ 2012 ๐ Journal of Virology
-
Amino acids 1055 to 1192 in the S2 region of severe acute respiratory syndrome coronavirus S protein induce neutralizing antibodies: Implications for the development of vaccines and antiviral agents
๐ค Keng, Choong Tat ๐ค Zhang, Aihua ๐ค Shen, Shuo ๐ค Lip, Kuo Ming ๐ค Fielding, Burtram C. ๐ค Tan, Timothy H.P. ๐ค Chou, Chih Fong ๐ค Chay, Boon Loh ๐ค Wang, Sifang ๐ค Fu, Jianlin ๐ค Yang, Xiaoming ๐ค Seng, Gee Lim ๐ค Hong, Wanjin ๐ค Tan, Yee Joo โฐ 2005 ๐ Journal of Virology
-
Medicinal herbal extracts of Sophorae radix, Acanthopanacis cortex, Sanguisorbae radix and Torilis fructus inhibit coronavirus replication in vitro
๐ค Kim, Hye Young ๐ค Eo, Eun Young ๐ค Park, Hyun ๐ค Kim, Youn Chul ๐ค Park, Sun ๐ค Shin, Ho Joon ๐ค Kim, Kyongmin โฐ 2010 ๐ Antiviral Therapy
-
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
๐ค Kirchdoerfer, Robert N. ๐ค Wang, Nianshuang ๐ค Pallesen, Jesper ๐ค Wrapp, Daniel ๐ค Turner, Hannah L. ๐ค Cottrell, Christopher A. ๐ค Corbett, Kizzmekia S. ๐ค Graham, Barney S. ๐ค McLellan, Jason S. ๐ค Ward, Andrew B. โฐ 2018 ๐ Scientific Reports
-
Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein
๐ค Kleine-Weber, Hannah ๐ค Elzayat, Mahmoud Tarek ๐ค Hoffmann, Markus ๐ค Pรถhlmann, Stefan โฐ 2018 ๐ Scientific Reports
-
In vitro antiviral activity of phlorotannins isolated from Ecklonia cava against porcine epidemic diarrhea coronavirus infection and hemagglutination
๐ค Kwon, Hyung Jun ๐ค Ryu, Young Bae ๐ค Kim, Young Min ๐ค Song, Naaleum ๐ค Kim, Cha Young ๐ค Rho, Mun Chual ๐ค Jeong, Jae Ho ๐ค Cho, Kyoung Oh ๐ค Lee, Woo Song ๐ค Park, Su Jin โฐ 2013 ๐ Bioorganic and Medicinal Chemistry
-
Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses.
๐ค Letko, Michael ๐ค Marzi, Andrea ๐ค Munster, Vincent โฐ 2020 ๐ Nat Microbiol
-
Conformational states of the severe acute respiratory syndrome coronavirus spike protein ectodomain
๐ค Li, Fang ๐ค Berardi, Marcelo ๐ค Li, Wenhui ๐ค Farzan, Michael ๐ค Dormitzer, Philip R. ๐ค Harrison, Stephen C. โฐ 2006 ๐ Journal of Virology
-
Expression of SARS-coronavirus envelope protein in Escherichia coli cells alters membrane permeability
๐ค Liao, Y. ๐ค Lescar, J. ๐ค Tam, J. P. ๐ค Liu, D. X. โฐ 2004 ๐ Biochemical and Biophysical Research Communications
-
Natural mutations in the receptor binding domain of spike glycoprotein determine the reactivity of cross-neutralization between palm civet coronavirus and severe acute respiratory syndrome coronavirus
๐ค Liu, Li ๐ค Fang, Qing ๐ค Deng, Fei ๐ค Wang, Hanzhong ๐ค Yi, Christopher E. ๐ค Ba, Lei ๐ค Yu, Wenjie ๐ค Lin, Richard D. ๐ค Li, Taisheng ๐ค Hu, Zhihong ๐ค Ho, David D. ๐ค Zhang, Linqi ๐ค Chen, Zhiwei โฐ 2007 ๐ Journal of Virology
-
Roles in cell-to-cell fusion of two conserved hydrophobic regions in the murine coronavirus spike protein
๐ค Luo, Zongli ๐ค Weiss, Susan R. โฐ 1998 ๐ Virology
-
Biochemical and biophysical characterization of the transmissible gastroenteritis coronavirus fusion core
๐ค Ma, Guangpeng ๐ค Feng, Youjun ๐ค Gao, Feng ๐ค Wang, Jinzi ๐ค Liu, Cheng ๐ค Li, Yijing โฐ 2005 ๐ Biochemical and Biophysical Research Communications
-
Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2
๐ค Matsuyama, Shutoku ๐ค Nagata, Noriyo ๐ค Shirato, Kazuya ๐ค Kawase, Miyuki ๐ค Takeda, Makoto ๐ค Taguchi, Fumihiro โฐ 2010 ๐ Journal of Virology
-
Communication between S1N330 and a region in S2 of murine coronavirus spike protein is important for virus entry into cells expressing CEACAM1b receptor
๐ค Matsuyama, Shutoku ๐ค Taguchi, Fumihiro โฐ 2002 ๐ Virology
-
Characterization of the prefusion and transition states of severe acute respiratory syndrome coronavirus S2-HR2
๐ค McReynolds, Susanna ๐ค Jiang, Shaokai ๐ค Guo, Ying ๐ค Celigoy, Jessica ๐ค Schar, Christine ๐ค Rong, Lijun ๐ค Caffrey, Michael โฐ 2008 ๐ Biochemistry
-
Dynamics of SARS-coronavirus HR2 domain in the prefusion and transition states
๐ค McReynolds, Susanna ๐ค Jiang, Shaokai ๐ค Rong, Lijun ๐ค Caffrey, Michael โฐ 2009 ๐ Journal of Magnetic Resonance
-
Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein
๐ค Mille, Jean Kaoru ๐ค Whittaker, Gary R. โฐ 2014 ๐ Proceedings of the National Academy of Sciences of the United States of America
-
Production of pseudotyped particles to study highly pathogenic coronaviruses in a biosafety level 2 setting
๐ค Millet, Jean K. ๐ค Tang, Tiffany ๐ค Nathan, Lakshmi ๐ค Jaimes, Javier A. ๐ค Hsu, Hung Lun ๐ค Daniel, Susan ๐ค Whittaker, Gary R. โฐ 2019 ๐ Journal of Visualized Experiments
-
Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3
๐ค Neuman, Benjamin W. ๐ค Joseph, Jeremiah S. ๐ค Saikatendu, Kumar S. ๐ค Serrano, Pedro ๐ค Chatterjee, Amarnath ๐ค Johnson, Margaret A. ๐ค Liao, Lujian ๐ค Klaus, Joseph P. ๐ค Yates III, John R. ๐ค Wรผthrich, Kurt ๐ค Stevens, Raymond C. ๐ค Buchmeier, Michael J. ๐ค Kuhn, Peter โฐ 2008 ๐ Journal of Virology
-
Substitution at aspartic acid 1128 in the SARS coronavirus spike glycoprotein mediates escape from a S2 domain-targeting neutralizing monoclonal antibody
๐ค Ng, Oi Wing ๐ค Keng, Choong Tat ๐ค Leung, Cynthia Sau Wai ๐ค Peiris, J. S.Malik ๐ค Poon, Leo Lit Man ๐ค Tan, Yee Joo โฐ 2014 ๐ PLoS ONE
-
Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae
๐ค O'Keefe, Barry R. ๐ค Giomarelli, Barbara ๐ค Barnard, Dale L. ๐ค Shenoy, Shilpa R. ๐ค Chan, Paul K.S. ๐ค McMahon, James B. ๐ค Palmer, Kenneth E. ๐ค Barnett, Brian W. ๐ค Meyerholz, David K. ๐ค Wohlford-Lenane, Christine L. ๐ค McCray Jr., Paul B. โฐ 2010 ๐ Journal of Virology
-
Inhibition of middle east respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody
๐ค Ohnuma, Kei ๐ค Haagmans, Bart L. ๐ค Hatano, Ryo ๐ค Raj, V. Stalin ๐ค Mou, Huihui ๐ค Iwata, Satoshi ๐ค Dang, Nam H. ๐ค Bosch, Berend Jan ๐ค Morimoto, Chikao โฐ 2013 ๐ Journal of Virology
-
Role of the lipid rafts in the life cycle of canine coronavirus
๐ค Pratelli, Annamaria ๐ค Colao, Valeriana โฐ 2015 ๐ Journal of General Virology
-
Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry
๐ค Qiu, Zhaozhu ๐ค Hingley, Susan T. ๐ค Simmons, Graham ๐ค Yu, Christopher ๐ค Das Sarma, Jayasri ๐ค Bates, Paul ๐ค Weiss, Susan R. โฐ 2006 ๐ Journal of Virology
-
Differential role for low pH and cathepsin-mediated cleavage of the viral spike protein during entry of serotype II feline coronaviruses
๐ค Regan, Andrew D. ๐ค Shraybman, Renata ๐ค Cohen, Rebecca D. ๐ค Whittaker, Gary R. โฐ 2008 ๐ Veterinary Microbiology
-
Potential therapies for coronaviruses
๐ค Savarino, Andrea ๐ค Bounavoglia, Canio ๐ค Norelli, Sandro ๐ค Di Trani, Livia ๐ค Cassone, Antonio โฐ 2006 ๐ Expert Opinion on Therapeutic Patents
-
Therapeutic opportunities to manage COVID-19/SARS-CoV-2 infection: Present and future.
๐ค Shetty, Rohit ๐ค Ghosh, Arkasubhra ๐ค Honavar, Santosh G ๐ค Khamar, Pooja ๐ค Sethu, Swaminathan โฐ 2020 ๐ Indian J Ophthalmol
-
Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry
๐ค Simmons, Graham ๐ค Reeves, Jacqueline D. ๐ค Rennekamp, Andrew J. ๐ค Amberg, Sean M. ๐ค Piefer, Andrew J. ๐ค Bates, Paul โฐ 2004 ๐ Proceedings of the National Academy of Sciences of the United States of America
-
Recent aspects on the pathogenesis mechanism, animal models and novel therapeutic interventions for middle east respiratory syndrome coronavirus infections
๐ค Skariyachan, Sinosh ๐ค Challapilli, Sneha Basavaraj ๐ค Packirisamy, Swathi ๐ค Kumargowda, Supreetha Toplar ๐ค Sridhar, Vaishnavi Sneha โฐ 2019 ๐ Frontiers in Microbiology
-
Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association
๐ค Sui, Jianhua ๐ค Li, Wenhui ๐ค Murakami, Akikazu ๐ค Tamin, Azaibi ๐ค Matthews, Leslie J. ๐ค Wong, Swee Kee ๐ค Moore, Michael J. ๐ค Tallarico, Aimee St Clair ๐ค Olurinde, Mobolaji ๐ค Choe, Hyeryun ๐ค Anderson, Larry J. ๐ค Bellini, William J. ๐ค Farzan, Michael ๐ค Marasco, Wayne A. โฐ 2004 ๐ Proceedings of the National Academy of Sciences of the United States of America
-
Structure of a proteolytically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion protein
๐ค Supekar, Vinit M. ๐ค Bruckmann, Chiara ๐ค Ingallinella, Paolo ๐ค Bianchi, Elisabetta ๐ค Pessi, Antonello ๐ค Carfi, Andrea โฐ 2004 ๐ Proceedings of the National Academy of Sciences of the United States of America
-
Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin
๐ค Ting, Du ๐ค Dong, Nan ๐ค Fang, Liurong ๐ค Lu, Jian ๐ค Bi, Jing ๐ค Xiao, Shaobo ๐ค Han, Heyou โฐ 2018 ๐ ACS Applied Nano Materials
-
Therapies for coronaviruses. Part 2: Inhibitors of intracellular life cycle
๐ค Tong, Tommy R. โฐ 2009 ๐ Expert Opinion on Therapeutic Patents
-
Therapies for coronaviruses. Part I of II - Viral entry inhibitors
๐ค Tong, Tommy R. โฐ 2009 ๐ Expert Opinion on Therapeutic Patents
-
Structural characterization of the SARS-coronavirus spike S fusion protein core
๐ค Tripet, Brian ๐ค Howard, Megan W. ๐ค Jobling, Michael ๐ค Holmes, Randall K. ๐ค Holmes, Kathryn V. ๐ค Hodges, Robert S. โฐ 2004 ๐ Journal of Biological Chemistry
-
Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus
๐ค Tripet, Brian ๐ค Kao, Daniel J. ๐ค Jeffers, Scott A. ๐ค Holmes, Kathryn V. ๐ค Hodges, Robert S. โฐ 2006 ๐ Journal of Structural Biology
-
Amino acid substitutions within the heptad repeat domain 1 of murine coronavirus spike protein restrict viral antigen spread in the central nervous system
๐ค Tsai, Jean C. ๐ค De Groot, Linda ๐ค Pinon, Josefina D. ๐ค Iacono, Kathryn T. ๐ค Phillips, Joanna J. ๐ค Seo, Su Hun ๐ค Lavi, Ehud ๐ค Weiss, Susan R. โฐ 2003 ๐ Virology
-
The N-terminal domain of the murine coronavirus spike glycoprotein determines the CEACAM1 receptor specificity of the virus strain
๐ค Tsai, Jean C. ๐ค Zelus, Bruce D. ๐ค Holmes, Kathryn V. ๐ค Weiss, Susan R. โฐ 2003 ๐ Journal of Virology
-
Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo-electron microscopy
๐ค Walls, Alexandra ๐ค Tortorici, M. Alejandra ๐ค Bosch, Berend Jan ๐ค Frenz, Brandon ๐ค Rottier, Peter J.M. ๐ค DiMaio, Frank ๐ค Rey, Felix A. ๐ค Veesler, David โฐ 2017 ๐ Protein Science
-
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein.
๐ค Walls, Alexandra C ๐ค Park, Young-Jun ๐ค Tortorici, M Alejandra ๐ค Wall, Abigail ๐ค McGuire, Andrew T ๐ค Veesler, David โฐ 2020 ๐ Cell
-
Molecular mechanism for antibody-dependent enhancement of coronavirus entry
๐ค Wan, Yushun ๐ค Shang, Jian ๐ค Sun, Shihui ๐ค Tai, Wanbo ๐ค Chen, Jing ๐ค Geng, Qibin ๐ค He, Lei ๐ค Chen, Yuehong ๐ค Wu, Jianming ๐ค Shi, Zhengli ๐ค Zhou, Yusen ๐ค Du, Lanying ๐ค Li, Fang โฐ 2020 ๐ Journal of Virology
-
Comparison of lentiviruses pseudotyped with S proteins from coronaviruses and cell tropisms of porcine coronaviruses
๐ค Wang, Jingjing ๐ค Deng, Feng ๐ค Ye, Gang ๐ค Dong, Wanyu ๐ค Zheng, Anjun ๐ค He, Qigai ๐ค Peng, Guiqing โฐ 2016 ๐ Virologica Sinica
-
Bat origins of MERS-CoV supported by bat Coronavirus HKU4 usage of human receptor CD26
๐ค Wang, Qihui ๐ค Qi, Jianxun ๐ค Yuan, Yuan ๐ค Xuan, Yifang ๐ค Han, Pengcheng ๐ค Wan, Yuhua ๐ค Ji, Wei ๐ค Li, Yan ๐ค Wu, Ying ๐ค Wang, Jianwei ๐ค Iwamoto, Aikichi ๐ค Woo, Patrick C.Y. ๐ค Yuen, Kwok Yung ๐ค Yan, Jinghua ๐ค Lu, Guangwen ๐ค Gao, George F. โฐ 2014 ๐ Cell Host and Microbe
-
IFITM proteins inhibit entry driven by the MERS-Coronavirus Spike protein: Evidence for Cholesterol-Independent Mechanisms
๐ค Wrensch, Florian ๐ค Winkler, Michael ๐ค Pรถhlmann, Stefan โฐ 2014 ๐ Viruses
-
Small molecules targeting severe acute respiratory syndrome human coronavirus
๐ค Wu, Chung Yi ๐ค Jan, Jia Tsrong ๐ค Ma, Shiou Hwa ๐ค Kuo, Chin Jung ๐ค Juan, Hsueh Fen ๐ค Cheng, Yih Shyun E. ๐ค Hsu, Hsien Hua ๐ค Huang, Hsuan Cheng ๐ค Wu, Douglass ๐ค Brik, Ashraf ๐ค Liang, Fu Sen ๐ค Liu, Rai Shung ๐ค Fang, Jim Min ๐ค Chen, Shui Tein ๐ค Liang, Po Huang ๐ค Wong, Chi Huey โฐ 2004 ๐ Proceedings of the National Academy of Sciences of the United States of America
-
Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein
๐ค Xia, Shuai ๐ค Liu, Qi ๐ค Wang, Qian ๐ค Sun, Zhiwu ๐ค Su, Shan ๐ค Du, Lanying ๐ค Ying, Tianlei ๐ค Lu, Lu ๐ค Jiang, Shibo โฐ 2014 ๐ Virus Research
-
Antibodies and vaccines against Middle East respiratory syndrome coronavirus
๐ค Xu, Jiuyang ๐ค Jia, Wenxu ๐ค Wang, Pengfei ๐ค Zhang, Senyan ๐ค Shi, Xuanling ๐ค Wang, Xinquan ๐ค Zhang, Linqi โฐ 2019 ๐ Emerging Microbes and Infections
-
Structural basis for coronavirus-mediated membrane fusion: Crystal structure of mouse hepatitis virus spike protein fusion core
๐ค Xu, Yanhui ๐ค Liu, Yiwei ๐ค Lou, Zhiyong ๐ค Qin, Lan ๐ค Li, Xu ๐ค Bai, Zhihong ๐ค Pang, Hai ๐ค Tien, Po ๐ค Gao, George F. ๐ค Rao, Zihe โฐ 2004 ๐ Journal of Biological Chemistry
-
Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core
๐ค Xu, Yanhui ๐ค Lou, Zhiyong ๐ค Liu, Yiwei ๐ค Pang, Hai ๐ค Tien, Po ๐ค Gao, George F. ๐ค Rao, Zihe โฐ 2004 ๐ Journal of Biological Chemistry
-
Proteolytic activation of the spike protein at a novel RRRR/S motif is implicated in furin-dependent entry, syncytium formation, and infectivity of coronavirus infectious bronchitis virus in cultured cells
๐ค Yamada, Yoshiyuki ๐ค Ding, Xiang Liu โฐ 2009 ๐ Journal of Virology
-
Biophysical characterization of HRC peptide analogs interaction with heptad repeat regions of the SARS-coronavirus Spike fusion protein core
๐ค Yan, Zhe ๐ค Tripet, Brian ๐ค Hodges, Robert S. โฐ 2006 ๐ Journal of Structural Biology
-
Targeting the Endocytic Pathway and Autophagy Process as a Novel Therapeutic Strategy in COVID-19.
๐ค Yang, Naidi ๐ค Shen, Han-Ming โฐ 2020 ๐ Int J Biol Sci
-
Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans
๐ค Yang, Tzu Jing ๐ค Chang, Yen Chen ๐ค Ko, Tzu Ping ๐ค Draczkowski, Piotr ๐ค Chien, Yu Chun ๐ค Chang, Yuan Chih ๐ค Wu, Kuen Phon ๐ค Khoo, Kay Hooi ๐ค Chang, Hui Wen ๐ค Danny Hsu, Shang Te โฐ 2020 ๐ Proceedings of the National Academy of Sciences of the United States of America
-
Two mutations were critical for bat-to-human transmission of middle east respiratory syndrome coronavirus
๐ค Yang, Yang ๐ค Liu, Chang ๐ค Du, Lanying ๐ค Jiang, Shibo ๐ค Shi, Zhengli ๐ค Baric, Ralph S. ๐ค Li, Fang โฐ 2015 ๐ Journal of Virology
-
pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN
๐ค Yang, Zhi Yong ๐ค Huang, Yue ๐ค Ganesh, Lakshmanan ๐ค Leung, Kwanyee ๐ค Kong, Wing Pui ๐ค Schwartz, Owen ๐ค Subbarao, Kanta ๐ค Nabel, Gary J. โฐ 2004 ๐ Journal of Virology
-
Severe acute respiratory syndrome coronavirus entry into host cells: Opportunities for therapeutic intervention
๐ค Yeung, Kap Sun ๐ค Yamanaka, Gregory A. ๐ค Meanwell, Nicholas A. โฐ 2006 ๐ Medicinal Research Reviews
-
Single amino acid substitutions in the severe acute respiratory syndrome coronavirus spike glycoprotein determine viral entry and immunogenicity of a major neutralizing domain
๐ค Yi, Christopher E. ๐ค Ba, Lei ๐ค Zhang, Linqi ๐ค Ho, David D. ๐ค Chen, Zhiwei โฐ 2005 ๐ Journal of Virology
-
Quantitative comparison of the efficiency of antibodies against S1 and S2 subunit of SARS coronavirus spike protein in virus neutralization and blocking of receptor binding: Implications for the functional roles of S2 subunit
๐ค Zeng, Fanya ๐ค Hon, Chung Chau ๐ค Yip, Chi Wai ๐ค Law, Ka Man ๐ค Yeung, Yin Shan ๐ค Chan, Kwok Hung ๐ค Malik Peiris, Joseph S. ๐ค Leung, Frederick Chi Ching โฐ 2006 ๐ FEBS Letters
-
Porcine deltacoronavirus enters cells via two pathways: A protease-mediated one at the cell surface and another facilitated by cathepsins in the endosome
๐ค Zhang, Jialin ๐ค Chen, Jianfei ๐ค Shi, Da ๐ค Shi, Hongyan ๐ค Zhang, Xin ๐ค Liu, Jianbo ๐ค Cao, Liyan ๐ค Zhu, Xiangdong ๐ค Liu, Ye ๐ค Wang, Xiaobo ๐ค Ji, Zhaoyang ๐ค Feng, Li โฐ 2019 ๐ Journal of Biological Chemistry
-
Cholesterol 25-hydroxylase negatively regulates porcine intestinal coronavirus replication by the production of 25-hydroxycholesterol
๐ค Zhang, Yunhang ๐ค Song, Zhongbao ๐ค Wang, Mi ๐ค Lan, Min ๐ค Zhang, Kuo ๐ค Jiang, Ping ๐ค Li, Yufeng ๐ค Bai, Juan ๐ค Wang, Xian Wei โฐ 2019 ๐ Veterinary Microbiology
-
Identification of residues controlling restriction versus enhancing activities of IFITM proteins on entry of human coronaviruses
๐ค Zhao, Xuesen ๐ค Sehgal, Mohit ๐ค Hou, Zhifei ๐ค Cheng, Junjun ๐ค Shu, Sainan ๐ค Wu, Shuo ๐ค Guo, Fang ๐ค Le Marchand, Sylvain J. ๐ค Lin, Hanxin ๐ค Chang, Jinhong ๐ค Guo, Ju Tao โฐ 2018 ๐ Journal of Virology
-
Core structure of S2 from the human coronavirus NL63 spike glycoprotein
๐ค Zheng, Qi ๐ค Deng, Yiqun ๐ค Liu, Jie ๐ค Van Der Hoek, Lia ๐ค Berkhout, Ben ๐ค Lu, Min โฐ 2006 ๐ Biochemistry
-
A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms
๐ค Zhou, Yanchen ๐ค Lu, Kai ๐ค Pfefferle, Susanne ๐ค Bertram, Stephanie ๐ค Glowacka, Ilona ๐ค Drosten, Christian ๐ค Pรถhlmann, Stefan ๐ค Simmons, Graham โฐ 2010 ๐ Journal of Virology
-
TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1
๐ค Zmora, Pawel ๐ค Hoffmann, Markus ๐ค Kollmus, Heike ๐ค Moldenhauer, Anna Sophie ๐ค Danov, Olga ๐ค Braun, Armin ๐ค Winkler, Michael ๐ค Schughart, Klaus ๐ค Stefan Pรถhlmann, X. โฐ 2018 ๐ Journal of Biological Chemistry