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🔗 novel coronavirus (684) 🔗 respiratory syndrome (2004) 🔗 acute respiratory (1734) 🔗 severe acute (1373) 🔗 neutralizing antibodies (122) 🔗 amino acid (454) 🔗 converting enzyme (162) 🔗 immune response (314) 🔗 data suggest (146) 🔗 immune responses (142) 🔗 angiotensin-converting enzyme (112) 🔗 amino acids (205) 🔗 main protease (44) 🔗 respiratory syndrome-associated (90) 🔗 syndrome-associated coronavirus (88) 🔗 viral entry (91) 🔗 cells expressing (60) 🔗 receptor angiotensin-converting (14) 🔗 infected cells (307) 🔗 receptor binding (86) 🔗 findings suggest (77) 🔗 mice immunized (25) 🔗 spike protein (353) 🔗 experimentally infected (47) 🔗 positively charged (16)

Articles (6)

Heterologous MVA-S prime Ad5-S boost regimen induces high and persistent levels of neutralizing antibody response against SARS coronavirus
👤 Ba, Lei 👤 Yi, Christopher E. 👤 Zhang, Linqi 👤 Ho, David D. 👤 Chen, Zhiwei ⏰ 2007 📚 Applied Microbiology and Biotechnology
Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region
👤 Chen, Zhiwei 👤 Zhang, Linqi 👤 Qin, Chuan 👤 Ba, Lei 👤 Yi, Christopher E. 👤 Zhang, Fengwen 👤 Wei, Qiang 👤 He, Tian 👤 Yu, Wenjie 👤 Yu, Jian 👤 Gao, Hong 👤 Tu, Xinming 👤 Gettie, Agegnehu 👤 Farzan, Michael 👤 Yuen, Kwok Yung 👤 Ho, David D. ⏰ 2005 📚 Journal of Virology
Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics
👤 Kao, Richard Y. 👤 Tsui, Wayne H.W. 👤 Lee, Terri S.W. 👤 Tanner, Julian A. 👤 Watt, Rory M. 👤 Huang, Jian Dong 👤 Hu, Lihong 👤 Chen, Guanhua 👤 Chen, Zhiwei 👤 Zhang, Linqi 👤 He, Tian 👤 Chan, Kwok Hung 👤 Tse, Herman 👤 To, Amanda P.C. 👤 Ng, Louisa W.Y. 👤 Wong, Bonnie C.W. 👤 Tsoi, Hoi Wah 👤 Yang, Dan 👤 Ho, David D. 👤 Yuen, Kwok Yung ⏰ 2004 📚 Chemistry and Biology
Natural mutations in the receptor binding domain of spike glycoprotein determine the reactivity of cross-neutralization between palm civet coronavirus and severe acute respiratory syndrome coronavirus
👤 Liu, Li 👤 Fang, Qing 👤 Deng, Fei 👤 Wang, Hanzhong 👤 Yi, Christopher E. 👤 Ba, Lei 👤 Yu, Wenjie 👤 Lin, Richard D. 👤 Li, Taisheng 👤 Hu, Zhihong 👤 Ho, David D. 👤 Zhang, Linqi 👤 Chen, Zhiwei ⏰ 2007 📚 Journal of Virology
SARS coronavirus spike polypeptide DNA vaccine priming with recombinant spike polypeptide from Escherichia coli as booster induces high titer of neutralizing antibody against SARS coronavirus
👤 Woo, Patrick C.Y. 👤 Lau, Susanna K.P. 👤 Tsoi, Hoi Wah 👤 Chen, Zhi Wei 👤 Wong, Beatrice H.L. 👤 Zhang, Linqi 👤 Chan, Jim K.H. 👤 Wong, Lei Po 👤 He, Wei 👤 Ma, Chi 👤 Chan, Kwok Hung 👤 Ho, David D. 👤 Yuen, Kwok Yung ⏰ 2005 📚 Vaccine
Single amino acid substitutions in the severe acute respiratory syndrome coronavirus spike glycoprotein determine viral entry and immunogenicity of a major neutralizing domain
👤 Yi, Christopher E. 👤 Ba, Lei 👤 Zhang, Linqi 👤 Ho, David D. 👤 Chen, Zhiwei ⏰ 2005 📚 Journal of Virology