π€ Simmons, Graham
Keywords
Articles (14)
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Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease
π€ Bertram, Stephanie π€ Glowacka, Ilona π€ MΓΌller, Marcel A. π€ Lavender, Hayley π€ Gnirss, Kerstin π€ Nehlmeier, Inga π€ Niemeyer, Daniela π€ He, Yuxian π€ Simmons, Graham π€ Drosten, Christian π€ Soilleux, Elizabeth J. π€ Jahn, Olaf π€ Steffen, Imke π€ PΓΆhlmann, Stefan β° 2011 π Journal of Virology
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The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies
π€ Gierer, Stefanie π€ Bertram, Stephanie π€ Kaup, Franziska π€ Wrensch, Florian π€ Heurich, Adeline π€ KrΓ€mer-KΓΌhl, Annika π€ Welsch, Kathrin π€ Winkler, Michael π€ Meyer, Benjamin π€ Drosten, Christian π€ Dittmer, Ulf π€ von Hahn, Thomas π€ Simmons, Graham π€ Hofmann, Heike π€ PΓΆhlmann, Stefan β° 2013 π Journal of Virology
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Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63
π€ Glowacka, Ilona π€ Bertram, Stephanie π€ Herzog, Petra π€ Pfefferle, Susanne π€ Steffen, Imke π€ Muench, Marcus O. π€ Simmons, Graham π€ Hofmann, Heike π€ Kuri, Thomas π€ Weber, Friedemann π€ Eichler, Jutta π€ Drosten, Christian π€ PΓΆhlmann, Stefan β° 2010 π Journal of Virology
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Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors
π€ Hofmann, Heike π€ Simmons, Graham π€ Rennekamp, Andrew J. π€ Chaipan, Chawaree π€ Gramberg, Thomas π€ Heck, Elke π€ Geier, Martina π€ Wegele, Anja π€ Marzi, Andrea π€ Bates, Paul π€ PΓΆhlmann, Stefan β° 2006 π Journal of Virology
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Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin
π€ Kumaki, Yohichi π€ Wandersee, Miles K. π€ Smith, Aaron J. π€ Zhou, Yanchen π€ Simmons, Graham π€ Nelson, Nathan M. π€ Bailey, Kevin W. π€ Vest, Zachary G. π€ Li, Joseph K.K. π€ Chan, Paul Kay Sheung π€ Smee, Donald F. π€ Barnard, Dale L. β° 2011 π Antiviral Research
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DC-SIGN and DC-SIGNR interact with the glycoprotein of marburg virus and the S protein of severe acute respiratory syndrome coronavirus
π€ Marzi, Andrea π€ Gramberg, Thomas π€ Simmons, Graham π€ MΓΆller, Peggy π€ Rennekamp, Andrew J. π€ Krumbiegel, Mandy π€ Geier, Martina π€ Eisemann, Jutta π€ Turza, Nadine π€ Saunier, Bertrand π€ Steinkasserer, Alexander π€ Becker, Stephan π€ Bates, Paul π€ Hofmann, Heike π€ PΓΆhlmann, Stefan β° 2004 π Journal of Virology
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Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry
π€ Qiu, Zhaozhu π€ Hingley, Susan T. π€ Simmons, Graham π€ Yu, Christopher π€ Das Sarma, Jayasri π€ Bates, Paul π€ Weiss, Susan R. β° 2006 π Journal of Virology
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Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion
π€ Simmons, Graham π€ Bertram, Stephanie π€ Glowacka, Ilona π€ Steffen, Imke π€ Chaipan, Chawaree π€ Agudelo, Juliet π€ Lu, Kai π€ Rennekamp, Andrew J. π€ Hofmann, Heike π€ Bates, Paul π€ PΓΆhlmann, Stefan β° 2011 π Virology
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Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
π€ Simmons, Graham π€ Gosalia, Dhaval N. π€ Rennekamp, Andrew J. π€ Reeves, Jacqueline D. π€ Diamond, Scott L. π€ Bates, Paul β° 2005 π Proceedings of the National Academy of Sciences of the United States of America
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Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry
π€ Simmons, Graham π€ Reeves, Jacqueline D. π€ Rennekamp, Andrew J. π€ Amberg, Sean M. π€ Piefer, Andrew J. π€ Bates, Paul β° 2004 π Proceedings of the National Academy of Sciences of the United States of America
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Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research
π€ Simmons, Graham π€ Zmora, Pawel π€ Gierer, Stefanie π€ Heurich, Adeline π€ PΓΆhlmann, Stefan β° 2013 π Antiviral Research
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Longitudinally profiling neutralizing antibody response to SARS coronavirus with pseudotypes
π€ Temperton, Nigel J. π€ Chan, Paul K. π€ Simmons, Graham π€ Zambon, Maria C. π€ Tedder, Richard S. π€ Takeuchi, Yasuhiro π€ Weiss, Robin A. β° 2005 π Emerging Infectious Diseases
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A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms
π€ Zhou, Yanchen π€ Lu, Kai π€ Pfefferle, Susanne π€ Bertram, Stephanie π€ Glowacka, Ilona π€ Drosten, Christian π€ PΓΆhlmann, Stefan π€ Simmons, Graham β° 2010 π Journal of Virology
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Protease inhibitors targeting coronavirus and filovirus entry
π€ Zhou, Yanchen π€ Vedantham, Punitha π€ Lu, Kai π€ Agudelo, Juliet π€ Carrion, Ricardo π€ Nunneley, Jerritt W. π€ Barnard, Dale π€ PΓΆhlmann, Stefan π€ McKerrow, James H. π€ Renslo, Adam R. π€ Simmons, Graham β° 2015 π Antiviral Research