🔗 Membrane fusion

Articles (105)

• Influence of hydrophobic and electrostatic residues on SARS-coronavirus S2 protein stability: Insights into mechanisms of general viral fusion and inhibitor design

  👤 Aydin, Halil 👤 Al-Khooly, Dina 👤 Lee, Jeffrey E. ⏰ 2014 📚 Protein Science

• Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites

  👤 Belouzard, Sandrine 👤 Chu, Victor C. 👤 Whittaker, Gary R. ⏰ 2009 📚 Proceedings of the National Academy of Sciences of the United States of America

• Elastase-mediated activation of the severe acute respiratory syndrome coronavirus spike protein at discrete sites within the S2 domain

  👤 Belouzard, Sandrine 👤 Madu, Ikenna 👤 Whittaker, Gary R. ⏰ 2010 📚 Journal of Biological Chemistry

• Conformational reorganization of the SARS coronavirus spike following receptor binding: Implications for membrane fusion

  👤 Beniac, Daniel R. 👤 de Varennes, Shauna L. 👤 Andonov, Anton 👤 He, Runtao 👤 Booth, Tim F. ⏰ 2007 📚 PLoS ONE

• Mutational analysis of the murine coronavirus spike protein: Effect on cell-to-cell fusion

  👤 Bos, Evelyne C.W. 👤 Heijnen, Leo 👤 Luytjes, Willem 👤 Spaan, Willy J.M. ⏰ 1995 📚 Virology

• Cathepsin L functionally cleaves the severe acute respiratory syndrome coronavirus class I fusion protein upstream of rather than adjacent to the fusion peptide

  👤 Bosch, Berend Jan 👤 Bartelink, Willem 👤 Rottier, Peter J.M. ⏰ 2008 📚 Journal of Virology

• Coronavirus spike glycoprotein, extended at the carboxy terminus with green fluorescent protein, is assembly competent

  👤 Bosch, Berend Jan 👤 De Haan, Cornelis A.M. 👤 Rottier, Peter J.M. ⏰ 2004 📚 Journal of Virology

• Spike protein assembly into the coronavirion: Exploring the limits of its sequence requirements

  👤 Bosch, Berend Jan 👤 De Haan, Cornelis A.M. 👤 Smits, Saskia L. 👤 Rottier, Peter J.M. ⏰ 2005 📚 Virology

• Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides

  👤 Bosch, Berend Jan 👤 Martina, Byron E.E. 👤 Van Der Zee, Ruurd 👤 Lepault, Jean 👤 Haijema, Bert Jan 👤 Versluis, Cees 👤 Heck, Albert J.R. 👤 De Groot, Raoul 👤 Osterhaus, Albert D.M.E. 👤 Rottier, Peter J.M. ⏰ 2004 📚 Proceedings of the National Academy of Sciences of the United States of America

• The coronavirus spike protein is a class I virus fusion protein: Structural and functional characterization of the fusion core complex

  👤 Bosch, Berend Jan 👤 Van der Zee, Ruurd 👤 De Haan, Cornelis A.M. 👤 Rottier, Peter J.M. ⏰ 2003 📚 Journal of Virology

• Important role for the transmembrane domain of severe acute respiratory syndrome coronavirus spike protein during entry

  👤 Broer, Rene 👤 Boson, Bertrand 👤 Spaan, Willy 👤 Cosset, François Loïc 👤 Corver, Jeroen ⏰ 2006 📚 Journal of Virology

• Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner

  👤 Burkard, Christine 👤 Verheije, Monique H. 👤 Wicht, Oliver 👤 van Kasteren, Sander I. 👤 van Kuppeveld, Frank J. 👤 Haagmans, Bart L. 👤 Pelkmans, Lucas 👤 Rottier, Peter J.M. 👤 Bosch, Berend Jan 👤 de Haan, Cornelis A.M. ⏰ 2014 📚 PLoS Pathogens

• Functional characterization of heptad repeat 1 and 2 mutants of the spike protein of severe acute respiratory syndrome coronavirus

  👤 Chan, Woan Eng 👤 Chuang, Chin Kai 👤 Yeh, Shiou Hwei 👤 Chang, Mau Sun 👤 Chen, Steve S.L. ⏰ 2006 📚 Journal of Virology

• Coronavirus-induced membrane fusion requires the cysteine-rich domain in the spike protein

  👤 Chang, Kevin W. 👤 Sheng, Yi Wei 👤 Gombold, James L. ⏰ 2000 📚 Virology

• Protective effect of intranasal regimens containing peptidic middle east respiratory syndrome coronavirus fusion inhibitor against MERS-CoV infection

  👤 Channappanavar, Rudragouda 👤 Lu, Lu 👤 Xia, Shuai 👤 Du, Lanying 👤 Meyerholz, David K. 👤 Perlman, Stanley 👤 Jiang, Shibo ⏰ 2015 📚 Journal of Infectious Diseases

• The use of hepatitis C virus NS3/4A and secreted alkaline phosphatase to quantitate cell-cell membrane fusion mediated by severe acute respiratory syndrome coronavirus S protein and the receptor angiotensin-converting enzyme 2

  👤 Chou, Chih Fong 👤 Shen, Shuo 👤 Mahadevappa, Geetha 👤 Lim, Seng Gee 👤 Hong, Wanjin 👤 Tan, Yee Joo ⏰ 2007 📚 Analytical Biochemistry

• Synthetic peptide studies on the Severe Acute Respiratory Syndrome (SARS) coronavirus spike glycoprotein: Perspective for SARS vaccine development

  👤 Choy, Wai Yan 👤 Lin, Shu Guang 👤 Chan, Paul Kay Sheung 👤 Tam, John Siu Lun 👤 Lo, Y. M.Dennis 👤 Chu, Ida Miu Ting 👤 Tsai, Sau Na 👤 Zhong, Ming Qi 👤 Fung, Kwok Pui 👤 Waye, Mary Miu Yee 👤 Tsui, Stephen Kwok Wing 👤 Ng, Kai On 👤 Shan, Zhi Xin 👤 Yang, Min 👤 Wu, Yi Long 👤 Lin, Zhan Yi 👤 Ngai, Sai Ming ⏰ 2004 📚 Clinical Chemistry

• Mutagenesis of the transmembrane domain of the SARS coronavirus spike glycoprotein: Refinement of the requirements for SARS coronavirus cell entry

  👤 Corver, Jeroen 👤 Broer, Rene 👤 Van Kasteren, Puck 👤 Spaan, Willy ⏰ 2009 📚 Virology Journal

• Single particle assay of coronavirus membrane fusion with proteinaceous receptor-embedded supported bilayers

  👤 Costello, Deirdre A. 👤 Millet, Jean K. 👤 Hsia, Chih Yun 👤 Whittaker, Gary R. 👤 Daniel, Susan ⏰ 2013 📚 Biomaterials

• Whole genome characterisation of quail deltacoronavirus detected in Poland

  👤 Domańska-Blicharz, Katarzyna 👤 Kuczkowski, Maciej 👤 Sajewicz-Krukowska, Joanna ⏰ 2019 📚 Virus Genes

• Central ions and lateral asparagine/glutamine zippers stabilize the post-fusion hairpin conformation of the SARS coronavirus spike glycoprotein

  👤 Duquerroy, Stéphane 👤 Vigouroux, Armelle 👤 Rottier, Peter J.M. 👤 Rey, Félix A. 👤 Jan Bosch, Berend ⏰ 2005 📚 Virology

• The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases

  👤 Earnest, James T. 👤 Hantak, Michael P. 👤 Li, Kun 👤 McCray, Paul B. 👤 Perlman, Stanley 👤 Gallagher, Tom ⏰ 2017 📚 PLoS Pathogens

• Coronavirus and influenza virus proteolytic priming takes place in tetraspanin-enriched membrane microdomains

  👤 Earnest, James T. 👤 Hantak, Michael P. 👤 Park, Jung Eun 👤 Gallagher, Tom ⏰ 2015 📚 Journal of Virology

• Cell entry by enveloped viruses: Redox considerations for HIV and SARS-coronavirus

  👤 Fenouillet, Emmanuel 👤 Barbouche, Rym 👤 Jones, Ian M. ⏰ 2007 📚 Antioxidants and Redox Signaling

• Serine-scanning mutagenesis studies of the C-terminal heptad repeats in the SARS coronavirus S glycoprotein highlight the important role of the short helical region

  👤 Follis, Kathryn E. 👤 York, Joanne 👤 Nunberg, Jack H. ⏰ 2005 📚 Virology

• Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell-cell fusion but does not affect virion entry

  👤 Follis, Kathryn E. 👤 York, Joanne 👤 Nunberg, Jack H. ⏰ 2006 📚 Virology

• Vesicular stomatitis virus pseudotyped with severe acute respiratory syndrome coronavirus spike protein

  👤 Fukushi, Shuetsu 👤 Mizutani, Tetsuya 👤 Saijo, Masayuki 👤 Matsuyama, Shutoku 👤 Miyajima, Naoko 👤 Taguchi, Fumihiro 👤 Itamura, Shigeyuki 👤 Kurane, Ichiro 👤 Morikawa, Shigeru ⏰ 2005 📚 Journal of General Virology

• Cell receptor-independent infection by a neurotropic murine coronavirus

  👤 Gallagher, Thomas M. 👤 Buchmeier, Michael J. 👤 Perlman, Stanley ⏰ 1992 📚 Virology

• Structure of the fusion core and inhibition of fusion by a heptad repeat peptide derived from the S protein of middle east respiratory syndrome coronavirus

  👤 Gao, Jing 👤 Lu, Guangwen 👤 Qi, Jianxun 👤 Li, Yan 👤 Wu, Ying 👤 Deng, Yao 👤 Geng, Heyuan 👤 Li, Hongbin 👤 Wang, Qihui 👤 Xiao, Haixia 👤 Tan, Wenjie 👤 Yan, Jinghua 👤 Gao, George F. ⏰ 2013 📚 Journal of Virology

• Identification of the membrane-active regions of the severe acute respiratory syndrome coronavirus spike membrane glycoprotein using a 16/18-mer peptide scan: Implications for the viral fusion mechanism

  👤 Guillén, Jaime 👤 Pérez-Berná, Ana J. 👤 Moreno, Miguel R. 👤 Villalaín, José ⏰ 2005 📚 Journal of Virology

• Solution structure of the severe acute respiratory syndrome-coronavirus heptad repeat 2 domain in the prefusion state

  👤 Hakansson-McReynolds, Susanna 👤 Jiang, Shaokai 👤 Rong, Lijun 👤 Caffrey, Michael ⏰ 2006 📚 Journal of Biological Chemistry

• Ready, set, fuse! the coronavirus spike protein and acquisition of fusion competence

  👤 Heald-Sargent, Taylor 👤 Gallagher, Tom ⏰ 2012 📚 Viruses

• TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein

  👤 Heurich, Adeline 👤 Hofmann-Winkler, Heike 👤 Gierer, Stefanie 👤 Liepold, Thomas 👤 Jahn, Olaf 👤 Pöhlmann, Stefan ⏰ 2014 📚 Journal of Virology

• Novel Gold Nanorod-Based HR1 Peptide Inhibitor for Middle East Respiratory Syndrome Coronavirus

  👤 Huang, Xinyu 👤 Li, Meng 👤 Xu, Yurui 👤 Zhang, Jikang 👤 Meng, Xia 👤 An, Xueying 👤 Sun, Lei 👤 Guo, Leilei 👤 Shan, Xue 👤 Ge, Junliang 👤 Chen, Jiao 👤 Luo, Yadong 👤 Wu, Heming 👤 Zhang, Yu 👤 Jiang, Qing 👤 Ning, Xinghai ⏰ 2019 📚 ACS Applied Materials and Interfaces

• TMPRSS2 contributes to virus spread and immunopathology in the airways of murine models after coronavirus infection

  👤 Iwata-Yoshikawa, Naoko 👤 Okamura, Tadashi 👤 Shimizu, Yukiko 👤 Hasegawa, Hideki 👤 Takeda, Makoto 👤 Nagata, Noriyo ⏰ 2019 📚 Journal of Virology

• Feline coronavirus: Insights into viral pathogenesis based on the spike protein structure and function

  👤 Jaimes, Javier A. 👤 Whittaker, Gary R. ⏰ 2018 📚 Virology

• Biochemical Analysis of Coronavirus Spike Glycoprotein Conformational Intermediates during Membrane Fusion

  👤 Kawase, Miyuki 👤 Kataoka, Michiyo 👤 Shirato, Kazuya 👤 Matsuyama, Shutoku ⏰ 2019 📚 Journal of virology

• Amino acids 1055 to 1192 in the S2 region of severe acute respiratory syndrome coronavirus S protein induce neutralizing antibodies: Implications for the development of vaccines and antiviral agents

  👤 Keng, Choong Tat 👤 Zhang, Aihua 👤 Shen, Shuo 👤 Lip, Kuo Ming 👤 Fielding, Burtram C. 👤 Tan, Timothy H.P. 👤 Chou, Chih Fong 👤 Chay, Boon Loh 👤 Wang, Sifang 👤 Fu, Jianlin 👤 Yang, Xiaoming 👤 Seng, Gee Lim 👤 Hong, Wanjin 👤 Tan, Yee Joo ⏰ 2005 📚 Journal of Virology

• Pre-fusion structure of a human coronavirus spike protein

  👤 Kirchdoerfer, Robert N. 👤 Cottrell, Christopher A. 👤 Wang, Nianshuang 👤 Pallesen, Jesper 👤 Yassine, Hadi M. 👤 Turner, Hannah L. 👤 Corbett, Kizzmekia S. 👤 Graham, Barney S. 👤 McLellan, Jason S. 👤 Ward, Andrew B. ⏰ 2016 📚 Nature

• Variations in disparate regions of the murine coronavirus spike protein impact the initiation of membrane fusion

  👤 Krueger, D. K. 👤 Kelly, S. M. 👤 Lewicki, D. N. 👤 Ruffolo, R. 👤 Gallagher, T. M. ⏰ 2001 📚 Journal of Virology

• Structural, glycosylation and antigenic variation between 2019 novel coronavirus (2019-nCoV) and SARS coronavirus (SARS-CoV).

  👤 Kumar, Swatantra 👤 Maurya, Vimal K 👤 Prasad, Anil K 👤 Bhatt, Madan L B 👤 Saxena, Shailendra K ⏰ 2020 📚 Virusdisease

• Development of human single-chain antibodies against SARS-associated coronavirus

  👤 Leung, K. M. 👤 Feng, D. X. 👤 Lou, Jianlong 👤 Zhou, Yu 👤 Fung, K. P. 👤 Waye, Mary M.Y. 👤 Tsui, Stephen K.W. 👤 Chan, Paul K.S. 👤 Marks, James D. 👤 Pang, S. F. 👤 Kan, Y. W. ⏰ 2008 📚 Intervirology

• Quaternary structure of coronavirus spikes in complex with carcinoembryonic antigen-related cell adhesion molecule cellular receptors

  👤 Lewicki, Daniel N. 👤 Gallagher, Thomas M. ⏰ 2002 📚 Journal of Biological Chemistry

• Coronavirus IBV-induced membrane fusion occurs at near-neutral pH

  👤 Li, D. 👤 Cavanagh, D. ⏰ 1992 📚 Archives of Virology

• Structure, Function, and Evolution of Coronavirus Spike Proteins

  👤 Li, Fang ⏰ 2016 📚 Annual Review of Virology

• Conformational states of the severe acute respiratory syndrome coronavirus spike protein ectodomain

  👤 Li, Fang 👤 Berardi, Marcelo 👤 Li, Wenhui 👤 Farzan, Michael 👤 Dormitzer, Philip R. 👤 Harrison, Stephen C. ⏰ 2006 📚 Journal of Virology

• A single point mutation creating a furin cleavage site in the spike protein renders porcine epidemic diarrhea coronavirus trypsin independent for cell entry and fusion

  👤 Li, Wentao 👤 Wicht, Oliver 👤 van Kuppeveld, Frank J.M. 👤 He, Qigai 👤 Rottier, Peter J.M. 👤 Bosch, Berend Jan ⏰ 2015 📚 Journal of Virology

• Characterization of the spike protein of human coronavirus NL63 in receptor binding and pseudotype virus entry

  👤 Lin, Han Xin 👤 Feng, Yan 👤 Tu, Xinming 👤 Zhao, Xuesen 👤 Hsieh, Chih Heng 👤 Griffin, Lauren 👤 Junop, Murray 👤 Zhang, Chengsheng ⏰ 2011 📚 Virus Research

• Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus

  👤 Lip, Kuo Ming 👤 Shen, Shuo 👤 Yang, Xiaoming 👤 Keng, Choong Tat 👤 Zhang, Aihua 👤 Oh, Hsueh Ling Janice 👤 Li, Zhi Hong 👤 Hwang, Le Ann 👤 Chou, Chih Fong 👤 Fielding, Burtram C. 👤 Tan, Timothy H.P. 👤 Mayrhofer, Josef 👤 Falkner, Falko G. 👤 Fu, Jianlin 👤 Lim, Seng Gee 👤 Hong, Wanjin 👤 Tan, Yee Joo ⏰ 2006 📚 Journal of Virology

• Characterization of HCoV-229E fusion core: Implications for structure basis of coronavirus membrane fusion

  👤 Liu, Cheng 👤 Feng, Youjun 👤 Gao, Feng 👤 Zhang, Qiangmin 👤 Wang, Ming ⏰ 2006 📚 Biochemical and Biophysical Research Communications

• Bat-to-human: Spike features determining 'host jump' of coronaviruses SARS-CoV, MERS-CoV, and beyond

  👤 Lu, Guangwen 👤 Wang, Qihui 👤 Gao, George F. ⏰ 2015 📚 Trends in Microbiology

• Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

  👤 Lu, Lu 👤 Liu, Qi 👤 Zhu, Yun 👤 Chan, Kwok Hung 👤 Qin, Lili 👤 Li, Yuan 👤 Wang, Qian 👤 Chan, Jasper Fuk Woo 👤 Du, Lanying 👤 Yu, Fei 👤 Ma, Cuiqing 👤 Ye, Sheng 👤 Yuen, Kwok Yung 👤 Zhang, Rongguang 👤 Jiang, Shibo ⏰ 2014 📚 Nature Communications

• Roles in cell-to-cell fusion of two conserved hydrophobic regions in the murine coronavirus spike protein

  👤 Luo, Zongli 👤 Weiss, Susan R. ⏰ 1998 📚 Virology

• Biochemical and biophysical characterization of the transmissible gastroenteritis coronavirus fusion core

  👤 Ma, Guangpeng 👤 Feng, Youjun 👤 Gao, Feng 👤 Wang, Jinzi 👤 Liu, Cheng 👤 Li, Yijing ⏰ 2005 📚 Biochemical and Biophysical Research Communications

• SARS-coronavirus spike S2 domain flanked by cysteine residues C822 and C833 is important for activation of membrane fusion

  👤 Madu, Ikenna G. 👤 Belouzard, Sandrine 👤 Whittaker, Gary R. ⏰ 2009 📚 Virology

• Characterization of a highly conserved domain within the severe acute respiratory syndrome coronavirus spike protein S2 domain with characteristics of a viral fusion peptide

  👤 Madu, Ikenna G. 👤 Roth, Shoshannah L. 👤 Belouzard, Sandrine 👤 Whittaker, Gary R. ⏰ 2009 📚 Journal of Virology

• Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2

  👤 Matsuyama, Shutoku 👤 Nagata, Noriyo 👤 Shirato, Kazuya 👤 Kawase, Miyuki 👤 Takeda, Makoto 👤 Taguchi, Fumihiro ⏰ 2010 📚 Journal of Virology

• Receptor-induced conformational changes of murine coronavirus spike protein

  👤 Matsuyama, Shutoku 👤 Taguchi, Fumihiro ⏰ 2002 📚 Journal of Virology

• Two-step conformational changes in a coronavirus envelope glycoprotein mediated by receptor binding and proteolysis

  👤 Matsuyama, Shutoku 👤 Taguchi, Fumihiro ⏰ 2009 📚 Journal of Virology

• Dynamics of SARS-coronavirus HR2 domain in the prefusion and transition states

  👤 McReynolds, Susanna 👤 Jiang, Shaokai 👤 Rong, Lijun 👤 Caffrey, Michael ⏰ 2009 📚 Journal of Magnetic Resonance

• Membrane Cholesterol Modulates Oligomeric Status and Peptide-Membrane Interaction of Severe Acute Respiratory Syndrome Coronavirus Fusion Peptide

  👤 Meher, Geetanjali 👤 Bhattacharjya, Surajit 👤 Chakraborty, Hirak ⏰ 2019 📚 Journal of Physical Chemistry B

• N-Terminal Domain of the Murine Coronavirus Receptor CEACAM1 Is Responsible for Fusogenic Activation and Conformational Changes of the Spike Protein

  👤 Miura, Hideka S. 👤 Nakagaki, Keiko 👤 Taguchi, Fumihiro ⏰ 2004 📚 Journal of Virology

• Identification of the fusion peptide-containing region in betacoronavirus spike glycoproteins

  👤 Ou, Xiuyuan 👤 Zheng, Wangliang 👤 Shan, Yiwei 👤 Mu, Zhixia 👤 Dominguez, Samuel R. 👤 Holmes, Kathryn V. 👤 Qian, Zhaohui ⏰ 2016 📚 Journal of Virology

• Lipidation increases antiviral activities of coronavirus fusion-inhibiting peptides

  👤 Park, Jung Eun 👤 Gallagher, Tom ⏰ 2017 📚 Virology

• Proteolytic processing of middle east respiratory syndrome coronavirus spikes expands virus tropism

  👤 Park, Jung Eun 👤 Li, Kun 👤 Barlan, Arlene 👤 Fehr, Anthony R. 👤 Perlman, Stanley 👤 McCray, Paul B. 👤 Gallagher, Tom ⏰ 2016 📚 Proceedings of the National Academy of Sciences of the United States of America

• Palmitoylation of the cysteine-rich endodomain of the SARS-coronavirus spike glycoprotein is important for spike-mediated cell fusion

  👤 Petit, Chad M. 👤 Chouljenko, Vladimir N. 👤 Iyer, Arun 👤 Colgrove, Robin 👤 Farzan, Michael 👤 Knipe, David M. 👤 Kousoulas, K. G. ⏰ 2007 📚 Virology

• Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion

  👤 Petit, Chad M. 👤 Melancon, Jeffrey M. 👤 Chouljenko, Vladimir N. 👤 Colgrove, Robin 👤 Farzan, Michael 👤 Knipe, David M. 👤 Kousoulas, K. G. ⏰ 2005 📚 Virology

• Identification of the receptor-binding domain of the spike glycoprotein of human betacoronavirus HKU1

  👤 Qian, Zhaohui 👤 Ou, Xiuyuan 👤 Góes, Luiz Gustavo Bentim 👤 Osborne, Christina 👤 Castano, Anna 👤 Holmes, Kathryn V. 👤 Dominguez, Samuel R. ⏰ 2015 📚 Journal of Virology

• The life cycle of SARS coronavirus in Vero E6 cells

  👤 Qinfen, Zhang 👤 Jinming, Cui 👤 Xiaojun, Huang 👤 Huanying, Zheng 👤 Jicheng, Huang 👤 Ling, Fang 👤 Kunpeng, Li 👤 Jingqiang, Zhang ⏰ 2004 📚 Journal of Medical Virology

• Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry

  👤 Qiu, Zhaozhu 👤 Hingley, Susan T. 👤 Simmons, Graham 👤 Yu, Christopher 👤 Das Sarma, Jayasri 👤 Bates, Paul 👤 Weiss, Susan R. ⏰ 2006 📚 Journal of Virology

• A conditional-lethal murine coronavirus mutant that fails to incorporate the spike glycoprotein into assembled virions

  👤 Ricard, Cynthia S. 👤 Koetzner, Cheri A. 👤 Sturman, Lawrence S. 👤 Masters, Paul S. ⏰ 1995 📚 Virus Research

• Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein

  👤 Sainz Jr., Bruno 👤 Mossel, Eric C. 👤 Gallaher, William R. 👤 Wimley, William C. 👤 Peters, C. J. 👤 Wilson, Russell B. 👤 Garry, Robert F. ⏰ 2006 📚 Virus Research

• The aromatic domain of the coronavirus class I viral fusion protein induces membrane permeabilization: Putative role during viral entry

  👤 Sainz Jr., Bruno 👤 Rausch, Joshua M. 👤 Gallaher, William R. 👤 Garry, Robert F. 👤 Wimley, William C. ⏰ 2005 📚 Biochemistry

• Gold nanoparticle-adjuvanted S protein induces a strong antigen-specific IgG response against severe acute respiratory syndrome-related coronavirus infection, but fails to induce protective antibodies and limit eosinophilic infiltration in lungs

  👤 Sekimukai, Hanako 👤 Iwata-Yoshikawa, Naoko 👤 Fukushi, Shuetsu 👤 Tani, Hideki 👤 Kataoka, Michiyo 👤 Suzuki, Tadaki 👤 Hasegawa, Hideki 👤 Niikura, Kenichi 👤 Arai, Katsuhiko 👤 Nagata, Noriyo ⏰ 2020 📚 Microbiology and Immunology

• Cryo-EM structure of infectious bronchitis coronavirus spike protein reveals structural and functional evolution of coronavirus spike proteins

  👤 Shang, Jian 👤 Zheng, Yuan 👤 Yang, Yang 👤 Liu, Chang 👤 Geng, Qibin 👤 Luo, Chuming 👤 Zhang, Wei 👤 Li, Fang ⏰ 2018 📚 PLoS Pathogens

• Cryo-electron microscopy structure of porcine deltacoronavirus spike protein in the prefusion state

  👤 Shang, Jian 👤 Zheng, Yuan 👤 Yang, Yang 👤 Liu, Chang 👤 Geng, Qibin 👤 Tai, Wanbo 👤 Du, Lanying 👤 Zhou, Yusen 👤 Zhang, Wei 👤 Li, Fang ⏰ 2018 📚 Journal of Virology

• A single amino acid mutation in the spike protein of coronavirus infectious bronchitis virus hampers its maturation and incorporation into virions at the nonpermissive temperature

  👤 Shen, S. 👤 Law, Y. C. 👤 Liu, D. X. ⏰ 2004 📚 Virology

• Role of spike protein endodomains in regulating coronavirus entry

  👤 Shulla, Ana 👤 Gallagher, Tom ⏰ 2009 📚 Journal of Biological Chemistry

• A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

  👤 Shulla, Ana 👤 Heald-Sargent, Taylor 👤 Subramanya, Gitanjali 👤 Zhao, Jincun 👤 Perlman, Stanley 👤 Gallagher, Tom ⏰ 2011 📚 Journal of Virology

• Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

  👤 Simmons, Graham 👤 Gosalia, Dhaval N. 👤 Rennekamp, Andrew J. 👤 Reeves, Jacqueline D. 👤 Diamond, Scott L. 👤 Bates, Paul ⏰ 2005 📚 Proceedings of the National Academy of Sciences of the United States of America

• Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

  👤 Simmons, Graham 👤 Reeves, Jacqueline D. 👤 Rennekamp, Andrew J. 👤 Amberg, Sean M. 👤 Piefer, Andrew J. 👤 Bates, Paul ⏰ 2004 📚 Proceedings of the National Academy of Sciences of the United States of America

• Proteolytic cleavage of the murine coronavirus surface glycoprotein is not required for fusion activity

  👤 Stauber, R. 👤 Pfleiderera, M. 👤 Siddell, S. ⏰ 1993 📚 Journal of General Virology

• Identification of a novel inhibitor against middle east respiratory syndrome coronavirus

  👤 Sun, Yaping 👤 Zhang, Huaidong 👤 Shi, Jian 👤 Zhang, Zhe 👤 Gong, Rui ⏰ 2017 📚 Viruses

• Soluble receptor potentiates receptor-independent infection by murine coronavirus

  👤 Taguchi, Fumihiro 👤 Matsuyama, Shutoku ⏰ 2002 📚 Journal of Virology

• Palmitoylations on murine coronavirus spike proteins are essential for virion assembly and infectivity

  👤 Thorp, Edward B. 👤 Boscarino, Joseph A. 👤 Logan, Hillary L. 👤 Goletz, Jeffrey T. 👤 Gallagher, Thomas M. ⏰ 2006 📚 Journal of Virology

• Requirements for CEACAMs and Cholesterol during Murine Coronavirus Cell Entry

  👤 Thorp, Edward B. 👤 Gallagher, Thomas M. ⏰ 2004 📚 Journal of Virology

• The carbohydrate-binding plant lectins and the non-peptidic antibiotic pradimicin A target the glycans of the coronavirus envelope glycoproteins

  👤 van der Meer, F. G.U.M. 👤 de Haan, C. A.M. 👤 Schuurman, N. M.P. 👤 Haijema, B. J. 👤 Verheije, M. H. 👤 Bosch, B. J. 👤 Balzarini, J. 👤 Egberink, H. F. ⏰ 2007 📚 Journal of Antimicrobial Chemotherapy

• Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo-electron microscopy

  👤 Walls, Alexandra 👤 Tortorici, M. Alejandra 👤 Bosch, Berend Jan 👤 Frenz, Brandon 👤 Rottier, Peter J.M. 👤 DiMaio, Frank 👤 Rey, Felix A. 👤 Veesler, David ⏰ 2017 📚 Protein Science

• Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

  👤 Walls, Alexandra C. 👤 Tortorici, M. Alejandra 👤 Bosch, Berend Jan 👤 Frenz, Brandon 👤 Rottier, Peter J.M. 👤 DiMaio, Frank 👤 Rey, Félix A. 👤 Veesler, David ⏰ 2016 📚 Nature

• Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

  👤 Walls, Alexandra C. 👤 Xiong, Xiaoli 👤 Park, Young Jun 👤 Tortorici, M. Alejandra 👤 Snijder, Joost 👤 Quispe, Joel 👤 Cameroni, Elisabetta 👤 Gopal, Robin 👤 Dai, Mian 👤 Lanzavecchia, Antonio 👤 Zambon, Maria 👤 Rey, Félix A. 👤 Corti, Davide 👤 Veesler, David ⏰ 2019 📚 Cell

• Identification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell

  👤 Wicht, Oliver 👤 Burkard, Christine 👤 de Haan, Cornelis A.M. 👤 van Kuppeveld, Frank J.M. 👤 Rottier, Peter J.M. 👤 Bosch, Berend Jan ⏰ 2014 📚 Journal of Virology

• Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein

  👤 Widjaja, Ivy 👤 Wang, Chunyan 👤 van Haperen, Rien 👤 Gutiérrez-Álvarez, Javier 👤 van Dieren, Brenda 👤 Okba, Nisreen M.A. 👤 Raj, V. Stalin 👤 Li, Wentao 👤 Fernandez-Delgado, Raul 👤 Grosveld, Frank 👤 van Kuppeveld, Frank J.M. 👤 Haagmans, Bart L. 👤 Enjuanes, Luis 👤 Drabek, Dubravka 👤 Bosch, Berend Jan ⏰ 2019 📚 Emerging Microbes and Infections

• Soluble receptor-mediated targeting of mouse hepatitis coronavirus to the human epidermal growth factor receptor

  👤 Würdinger, T. 👤 Verheije, M. H. 👤 Broen, K. 👤 Bosch, B. J. 👤 Haijema, B. J. 👤 De Haan, C. A.M. 👤 Van Beusechem, V. W. 👤 Gerritsen, W. R. 👤 Rottier, P. J.M. ⏰ 2005 📚 Journal of Virology

• Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibody

  👤 Würdinger, T. 👤 Verheije, M. H. 👤 Raaben, M. 👤 Bosch, B. J. 👤 de Haan, C. A.M. 👤 van Beusechem, V. W. 👤 Rottier, P. J.M. 👤 Gerritsen, W. R. ⏰ 2005 📚 Gene Therapy

• Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion.

  👤 Xia, Shuai 👤 Liu, Meiqin 👤 Wang, Chao 👤 Xu, Wei 👤 Lan, Qiaoshuai 👤 Feng, Siliang 👤 Qi, Feifei 👤 Bao, Linlin 👤 Du, Lanying 👤 Liu, Shuwen 👤 Qin, Chuan 👤 Sun, Fei 👤 Shi, Zhengli 👤 Zhu, Yun 👤 Jiang, Shibo 👤 Lu, Lu ⏰ 2020 📚 Cell Res

• Structural basis for coronavirus-mediated membrane fusion: Crystal structure of mouse hepatitis virus spike protein fusion core

  👤 Xu, Yanhui 👤 Liu, Yiwei 👤 Lou, Zhiyong 👤 Qin, Lan 👤 Li, Xu 👤 Bai, Zhihong 👤 Pang, Hai 👤 Tien, Po 👤 Gao, George F. 👤 Rao, Zihe ⏰ 2004 📚 Journal of Biological Chemistry

• Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core

  👤 Xu, Yanhui 👤 Lou, Zhiyong 👤 Liu, Yiwei 👤 Pang, Hai 👤 Tien, Po 👤 Gao, George F. 👤 Rao, Zihe ⏰ 2004 📚 Journal of Biological Chemistry

• Replication of murine coronavirus requires multiple cysteines in the endodomain of spike protein

  👤 Yang, Jinhua 👤 Lv, Jun 👤 Wang, Yuyan 👤 Gao, Shuang 👤 Yao, Qianqian 👤 Qu, Di 👤 Ye, Rong ⏰ 2012 📚 Virology

• Conformational changes in the spike glycoprotein of murine coronavirus are induced at 37°C either by soluble murine CEACAM1 receptors or by pH 8

  👤 Zelus, Bruce D. 👤 Schickli, Jeanne H. 👤 Blau, Dianna M. 👤 Weiss, Susan R. 👤 Holmes, Kathryn V. ⏰ 2003 📚 Journal of Virology

• Adaptive evolution of the spike gene of SARS coronavirus: Changes in positively selected sites in different epidemic groups

  👤 Zhang, Chi Yu 👤 Wei, Ji Fu 👤 He, Shao Ng ⏰ 2006 📚 BMC Microbiology

• Porcine deltacoronavirus enters cells via two pathways: A protease-mediated one at the cell surface and another facilitated by cathepsins in the endosome

  👤 Zhang, Jialin 👤 Chen, Jianfei 👤 Shi, Da 👤 Shi, Hongyan 👤 Zhang, Xin 👤 Liu, Jianbo 👤 Cao, Liyan 👤 Zhu, Xiangdong 👤 Liu, Ye 👤 Wang, Xiaobo 👤 Ji, Zhaoyang 👤 Feng, Li ⏰ 2019 📚 Journal of Biological Chemistry

• Inhibition of endoplasmic reticulum-resident glucosidases impairs severe acute respiratory syndrome coronavirus and human coronavirus NL63 spike protein-mediated entry by altering the glycan processing of angiotensin I-converting enzyme 2

  👤 Zhao, Xuesen 👤 Guo, Fang 👤 Comunale, Mary Ann 👤 Mehta, Anand 👤 Sehgal, Mohit 👤 Jain, Pooja 👤 Cuconati, Andrea 👤 Lin, Hanxin 👤 Block, Timothy M. 👤 Chang, Jinhong 👤 Guo, Ju Tao ⏰ 2015 📚 Antimicrobial Agents and Chemotherapy

• Core structure of S2 from the human coronavirus NL63 spike glycoprotein

  👤 Zheng, Qi 👤 Deng, Yiqun 👤 Liu, Jie 👤 Van Der Hoek, Lia 👤 Berkhout, Ben 👤 Lu, Min ⏰ 2006 📚 Biochemistry

• Lysosomal proteases are a determinant of coronavirus tropism

  👤 Zheng, Yuan 👤 Shang, Jian 👤 Yang, Yang 👤 Liu, Chang 👤 Wan, Yushun 👤 Geng, Qibin 👤 Wang, Michelle 👤 Baric, Ralph 👤 Li, Fang ⏰ 2018 📚 Journal of Virology

• A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms

  👤 Zhou, Yanchen 👤 Lu, Kai 👤 Pfefferle, Susanne 👤 Bertram, Stephanie 👤 Glowacka, Ilona 👤 Drosten, Christian 👤 Pöhlmann, Stefan 👤 Simmons, Graham ⏰ 2010 📚 Journal of Virology