π Transgenic mice
Articles (28)
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Generation of a transgenic mouse model of middle east respiratory syndrome coronavirus infection and disease
π€ Agrawal, Anurodh Shankar π€ Garron, Tania π€ Tao, Xinrong π€ Peng, Bi Hung π€ Wakamiya, Maki π€ Chan, Teh Sheng π€ Couch, Robert B. π€ Tseng, Chien Te K. β° 2015 π Journal of Virology
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Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection
π€ Agrawal, Anurodh Shankar π€ Ying, Tianlei π€ Tao, Xinrong π€ Garron, Tania π€ Algaissi, Abdullah π€ Wang, Yanping π€ Wang, Lili π€ Peng, Bi Hung π€ Jiang, Shibo π€ Dimitrov, Dimiter S. π€ Tseng, Chien Te K. β° 2016 π Scientific Reports
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Elevated human dipeptidyl peptidase 4 expression reduces the susceptibility of hDPP4 transgenic mice to middle east respiratory syndrome coronavirus infection and disease
π€ Algaissi, Abdullah π€ Agrawal, Anurodh S. π€ Han, Song π€ Peng, Bi Hung π€ Luo, Chuming π€ Li, Fang π€ Chan, Teh Sheng π€ Couch, Robert B. π€ Tseng, Chien Te K. β° 2019 π Journal of Infectious Diseases
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A Comparative Review of Animal Models of Middle East Respiratory Syndrome Coronavirus Infection
π€ Baseler, L. π€ de Wit, E. π€ Feldmann, H. β° 2016 π Veterinary Pathology
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Induction of T-cell response by a DNA vaccine encoding a novel HLA-A*0201 severe acute respiratory syndrome coronavirus epitope
π€ Cheung, Ying Kit π€ Cheng, Samuel Chak Sum π€ Sin, Fion Wan Yee π€ Chan, Kin Tak π€ Xie, Yong β° 2007 π Vaccine
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Neutralizing human monoclonal antibodies to severe acute respiratory syndrome coronavirus: Target, mechanism of action, and therapeutic potential
π€ Coughlin, Melissa M. π€ Prabhakar, Bellur S. β° 2012 π Reviews in Medical Virology
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Neuroprotective effect of apolipoprotein D against human coronavirus OC43-induced encephalitis in mice
π€ Do Carmo, Sonia π€ Jacomy, HΓ©lΓ¨ne π€ Talbot, Pierre J. π€ Rassart, Eric β° 2008 π Journal of Neuroscience
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Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines
π€ Du, Lanying π€ Tai, Wanbo π€ Yang, Yang π€ Zhao, Guangyu π€ Zhu, Qing π€ Sun, Shihui π€ Liu, Chang π€ Tao, Xinrong π€ Tseng, Chien Te K. π€ Perlman, Stanley π€ Jiang, Shibo π€ Zhou, Yusen π€ Li, Fang β° 2016 π Nature Communications
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Inhibition of interferon-Ξ³ signaling in oligodendroglia delays coronavirus clearance without altering demyelination
π€ GonzΓ‘lez, John M. π€ Bergmann, Cornelia C. π€ Ramakrishna, Chandran π€ Hinton, David R. π€ Atkinson, Roscoe π€ Hoskin, Jason π€ Macklin, Wendy B. π€ Stohlman, Stephen A. β° 2006 π American Journal of Pathology
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Bystander CD4 T cells do not mediate demyelination in mice infected with a neurotropic coronavirus
π€ Haring, Jodie S. π€ Perlman, Stanley β° 2003 π Journal of Neuroimmunology
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TMPRSS2 contributes to virus spread and immunopathology in the airways of murine models after coronavirus infection
π€ Iwata-Yoshikawa, Naoko π€ Okamura, Tadashi π€ Shimizu, Yukiko π€ Hasegawa, Hideki π€ Takeda, Makoto π€ Nagata, Noriyo β° 2019 π Journal of Virology
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Acute respiratory infection in human dipeptidyl peptidase 4-transgenic mice infected with Middle East respiratory syndrome coronavirus
π€ Iwata-Yoshikawa, Naoko π€ Okamura, Tadashi π€ Shimizu, Yukiko π€ Kotani, Osamu π€ Sato, Hironori π€ Sekimukai, Hanako π€ Fukushi, Shuetsu π€ Suzuki, Tadaki π€ Sato, Yuko π€ Takeda, Makoto π€ Tashiro, Masato π€ Hasegawa, Hideki π€ Nagata, Noriyo β° 2019 π Journal of Virology
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Development of a transgenic mouse model susceptible to human coronavirus 229E
π€ Lassnig, Caroline π€ Sanchez, Carlos M. π€ Egerbacher, Monika π€ Walter, Ingrid π€ Majer, Susanne π€ Kolbe, Thomas π€ Pallares, Pilar π€ Enjuanes, Luis π€ MΓΌller, Mathias β° 2005 π Proceedings of the National Academy of Sciences of the United States of America
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Middle east respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4
π€ Li, Kun π€ Wohlford-Lenane, Christine π€ Perlman, Stanley π€ Zhao, Jincun π€ Jewell, Alexander K. π€ Reznikov, Leah R. π€ Gibson-Corley, Katherine N. π€ Meyerholz, David K. π€ McCray, Paul B. β° 2015 π Journal of Infectious Diseases
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Induction of neutralising antibodies and cellular immune responses against SARS coronavirus by recombinant measles viruses
π€ Liniger, Matthias π€ Zuniga, Armando π€ Tamin, Azaibi π€ Azzouz-Morin, Teldja N. π€ Knuchel, Marlyse π€ Marty, Rene R. π€ Wiegand, Marian π€ Weibel, Sara π€ Kelvin, David π€ Rota, Paul A. π€ Naim, Hussein Y. β° 2008 π Vaccine
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The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
π€ Liu, Jun π€ Sun, Yeping π€ Qi, Jianxun π€ Chu, Fuliang π€ Wu, Hao π€ Gao, Feng π€ Li, Taisheng π€ Yan, Jinghua π€ Gao, George F. β° 2010 π Journal of Infectious Diseases
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Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus
π€ Mangale, Vrushali π€ Marro, Brett S. π€ Plaisted, Warren C. π€ Walsh, Craig M. π€ Lane, Thomas E. β° 2017 π Virology
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Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus
π€ McCray Jr., Paul B. π€ Pewe, Lecia π€ Wohlford-Lenane, Christine π€ Hickey, Melissa π€ Manzel, Lori π€ Shi, Lei π€ Netland, Jason π€ Jia, Hong Peng π€ Halabi, Carmen π€ Sigmund, Curt D. π€ Meyerholz, David K. π€ Kirby, Patricia π€ Look, Dwight C. π€ Perlman, Stanley β° 2007 π Journal of Virology
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Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen
π€ Nyon, Mun Peak π€ Du, Lanying π€ Tseng, Chien Te Kent π€ Seid, Christopher A. π€ Pollet, Jeroen π€ Naceanceno, Kevin S. π€ Agrawal, Anurodh π€ Algaissi, Abdullah π€ Peng, Bi Hung π€ Tai, Wanbo π€ Jiang, Shibo π€ Bottazzi, Maria Elena π€ Strych, Ulrich π€ Hotez, Peter J. β° 2018 π Vaccine
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Synthetic peptides coupled to the surface of liposomes effectively induce SARS coronavirus-specific cytotoxic T lymphocytes and viral clearance in HLA-A*0201 transgenic mice
π€ Ohno, Satoshi π€ Kohyama, Shunsuke π€ Taneichi, Maiko π€ Moriya, Osamu π€ Hayashi, Hidenori π€ Oda, Hiroshi π€ Mori, Masahito π€ Kobayashi, Akiharu π€ Akatsuka, Toshitaka π€ Uchida, Tetsuya π€ Matsui, Masanori β° 2009 π Vaccine
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HLA-A*0201 T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus nucleocapsid and spike proteins
π€ Tsao, Yeou Ping π€ Lin, Jian Yu π€ Jan, Jia Tsrong π€ Leng, Chih Hsiang π€ Chu, Chen Chung π€ Yang, Yuh Cheng π€ Chen, Show Li β° 2006 π Biochemical and Biophysical Research Communications
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Severe acute respiratory syndrome coronavirus infection of mice transgenic for the human angiotensin-converting enzyme 2 virus receptor
π€ Tseng, Chien Te K. π€ Huang, Cheng π€ Newman, Patrick π€ Wang, Nan π€ Narayanan, Krishna π€ Watts, Douglas M. π€ Makino, Shinji π€ Packard, Michelle M. π€ Zaki, Sherif R. π€ Chan, Teh Sheng π€ Peters, Clarence J. β° 2007 π Journal of Virology
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Animal models of Middle East respiratory syndrome coronavirus infection
π€ Van Doremalen, Neeltje π€ Munster, Vincent J. β° 2015 π Antiviral Research
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Development of a dose-response model for SARS coronavirus
π€ Watanabe, Toru π€ Bartrand, Timothy A. π€ Weir, Mark H. π€ Omura, Tatsuo π€ Haas, Charles N. β° 2010 π Risk Analysis
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Cells of human aminopeptidase N (CD13) transgenic mice are infected by human coronavirus-229E in vitro, but not in vivo
π€ Wentworth, David E. π€ Tresnan, D. B. π€ Turner, B. C. π€ Lerman, I. R. π€ Bullis, B. π€ Hemmila, E. M. π€ Levis, R. π€ Shapiro, L. H. π€ Holmes, Kathryn V. β° 2005 π Virology
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Airway Memory CD4+ T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses
π€ Zhao, Jincun π€ Zhao, Jingxian π€ Mangalam, Ashutosh K. π€ Channappanavar, Rudragouda π€ Fett, Craig π€ Meyerholz, David K. π€ Agnihothram, Sudhakar π€ Baric, Ralph S. π€ David, Chella S. π€ Perlman, Stanley β° 2016 π Immunity
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Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus
π€ Zhou, Jie π€ Li, Cun π€ Zhao, Guangyu π€ Chu, Hin π€ Wang, Dong π€ Yan, Helen Hoi Ning π€ Poon, Vincent Kwok Man π€ Wen, Lei π€ Wong, Bosco Ho Yin π€ Zhao, Xiaoyu π€ Chiu, Man Chun π€ Yang, Dong π€ Wang, Yixin π€ Au-Yeung, Rex K.H. π€ Chan, Ivy Hau Yee π€ Sun, Shihui π€ Chan, Jasper Fuk Woo π€ To, Kelvin Kai Wang π€ Memish, Ziad A. π€ Corman, Victor M. π€ Drosten, Christian π€ Hung, Ivan Fan Ngai π€ Zhou, Yusen π€ Leung, Suet Yi π€ Yuen, Kwok Yung β° 2017 π Science Advances
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Screening and identification of severe acute respiratory syndrome-associated coronavirus-specific CTL epitopes
π€ Zhou, Minghai π€ Xu, Dongping π€ Li, Xiaojuan π€ Li, Hongtao π€ Shan, Ming π€ Tang, Jiaren π€ Wang, Min π€ Wang, Fu Sheng π€ Zhu, Xiaodong π€ Tao, Hua π€ He, Wei π€ Tien, Po π€ Gao, George F. β° 2006 π Journal of Immunology