chen-shuai

Keywords

🔗 severe acute (1373) 🔗 syndrome coronavirus (1074) 🔗 resonance energy (16) 🔗 plasmon resonance (20) 🔗 respiratory syndrome (2004) 🔗 acute respiratory (1734) 🔗 energy transfer (19) 🔗 enzymatic activity (29) 🔗 site-directed mutagenesis (23) 🔗 human coronavirus (623) 🔗 results suggest (206) 🔗 viral replication (258) 🔗 first report (99) 🔗 crystal structure (114) 🔗 life cycle (63) 🔗 public health (392) 🔗 etiological agent (62) 🔗 infectious disease (312) 🔗 novel coronavirus (684) 🔗 present study (186) 🔗 important role (140)

Articles (8)

Discovering severe acute respiratory syndrome coronavirus 3CL protease inhibitors: Virtual screening, surface plasmon resonance, and fluorescence resonance energy transfer assays
👤 Chen, Lili 👤 Chen, Shuai 👤 Gui, Chunshan 👤 Shen, Jianhua 👤 Shen, Xu 👤 Jiang, Hualiang ⏰ 2006 📚 Journal of Biomolecular Screening
Enzymatic activity characterization of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer technique
👤 Chen, Shuai 👤 Chen, Li Li 👤 Luo, Hai Bin 👤 Sun, Tao 👤 Chen, Jing 👤 Ye, Fei 👤 Cai, Jian Hua 👤 Shen, Jing Kang 👤 Shen, Xu 👤 Jiang, Hua Liang ⏰ 2005 📚 Acta Pharmacologica Sinica
Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization: Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations
👤 Chen, Shuai 👤 Chen, Lili 👤 Tan, Jinzhi 👤 Chen, Jing 👤 Du, Li 👤 Sun, Tao 👤 Shen, Jianhua 👤 Chen, Kaixian 👤 Jiang, Hualiang 👤 Shen, Xu ⏰ 2005 📚 Journal of Biological Chemistry
Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: Crystal structure with molecular dynamics simulations
👤 Chen, Shuai 👤 Hu, Tiancen 👤 Zhang, Jian 👤 Chen, Jing 👤 Chen, Kaixian 👤 Ding, Jianping 👤 Jiang, Hualiang 👤 Shen, Xu ⏰ 2008 📚 Journal of Biological Chemistry
An overall picture of SARS coronavirus (SARS-CoV) genome-encoded major proteins: Structures, functions and drug development
👤 Chen, Shuai 👤 Luo, Haibin 👤 Chen, Lili 👤 Chen, Jing 👤 Shen, Jianhua 👤 Zhu, Weiliang 👤 Chen, Kaixian 👤 Shen, Xu 👤 Jiang, Hualiang ⏰ 2006 📚 Current Pharmaceutical Design
Residues on the dimer interface of SARS coronavirus 3C-like protease: Dimer stability characterization and enzyme catalytic activity analysis
👤 Chen, Shuai 👤 Zhang, Jian 👤 Hu, Tiancen 👤 Chen, Kaixian 👤 Jiang, Hualiang 👤 Shen, Xu ⏰ 2008 📚 Journal of Biochemistry
Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure
👤 Hu, Tiancen 👤 Zhang, Yu 👤 Li, Lianwei 👤 Wang, Kuifeng 👤 Chen, Shuai 👤 Chen, Jing 👤 Ding, Jianping 👤 Jiang, Hualiang 👤 Shen, Xu ⏰ 2009 📚 Virology
A Structural View of the Inactivation of the SARS Coronavirus Main Proteinase by Benzotriazole Esters
👤 Verschueren, Koen H.G. 👤 Pumpor, Ksenia 👤 Anemüller, Stefan 👤 Chen, Shuai 👤 Mesters, Jeroen R. 👤 Hilgenfeld, Rolf ⏰ 2008 📚 Chemistry and Biology