🔗 Site-directed mutagenesis

Articles (23)

• Influence of hydrophobic and electrostatic residues on SARS-coronavirus S2 protein stability: Insights into mechanisms of general viral fusion and inhibitor design

  👤 Aydin, Halil 👤 Al-Khooly, Dina 👤 Lee, Jeffrey E. ⏰ 2014 📚 Protein Science

• The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity

  👤 Barretto, Naina 👤 Jukneliene, Dalia 👤 Ratia, Kiira 👤 Chen, Zhongbin 👤 Mesecar, Andrew D. 👤 Baker, Susan C. ⏰ 2005 📚 Journal of Virology

• Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein

  👤 Chen, I. Jung 👤 Yuann, Jeu Ming P. 👤 Chang, Yu Ming 👤 Lin, Shing Yen 👤 Zhao, Jincun 👤 Perlman, Stanley 👤 Shen, Yo Yu 👤 Huang, Tai Huang 👤 Hou, Ming Hon ⏰ 2013 📚 Biochimica et Biophysica Acta - Proteins and Proteomics

• Enzymatic activity characterization of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer technique

  👤 Chen, Shuai 👤 Chen, Li Li 👤 Luo, Hai Bin 👤 Sun, Tao 👤 Chen, Jing 👤 Ye, Fei 👤 Cai, Jian Hua 👤 Shen, Jing Kang 👤 Shen, Xu 👤 Jiang, Hua Liang ⏰ 2005 📚 Acta Pharmacologica Sinica

• Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase

  👤 Chen, Yu 👤 Tao, Jiali 👤 Sun, Ying 👤 Wu, Andong 👤 Su, Ceyang 👤 Gao, Guozhen 👤 Cai, Hui 👤 Qiu, Su 👤 Wu, Yingliang 👤 Tero Ahola, None 👤 Guo, Deyin ⏰ 2013 📚 Journal of Virology

• Identification of a golgi complex-targeting signal in the cytoplasmic tail of the severe acute respiratory syndrome coronavirus envelope protein

  👤 Cohen, Jennifer R. 👤 Lin, Lisa D. 👤 Machamer, Carolyn E. ⏰ 2011 📚 Journal of Virology

• Structure and functional relevance of a transcription-regulating sequence involved in coronavirus discontinuous RNA synthesis

  👤 Dufour, David 👤 Mateos-Gomez, Pedro A. 👤 Enjuanes, Luis 👤 Gallego, José 👤 Sola, Isabel ⏰ 2011 📚 Journal of Virology

• The viral nucleocapsid protein of transmissible gastroenteritis coronavirus (TGEV) is cleaved by caspase-6 and -7 during TGEV-induced apoptosis

  👤 Eléouët, Jean François 👤 Slee, Elizabeth A. 👤 Saurini, Françoise 👤 Castagné, Nathalie 👤 Poncet, Didier 👤 Garrido, Carmen 👤 Solary, Eric 👤 Martin, Seamus J. ⏰ 2000 📚 Journal of Virology

• A combination of mutations in the S1 part of the spike glycoprotein gene of coronavirus MHV-A59 abolishes demyelination

  👤 Fu, Li 👤 Gonzales, Donna M. 👤 Das Sarma, Jayasri 👤 Lavi, Ehud ⏰ 2004 📚 Journal of NeuroVirology

• In vitro and in ovo expression of chicken gamma interferon by a defective RNA of avian coronavirus infectious bronchitis virus

  👤 Hackney, Karen 👤 Cavanagh, Dave 👤 Kaiser, Pete 👤 Britton, Paul ⏰ 2003 📚 Journal of Virology

• SARS-coronavirus protein 6 conformations required to impede protein import into the nucleus

  👤 Hussain, Snawar 👤 Gallagher, Tom ⏰ 2010 📚 Virus Research

• The missing link in coronavirus assembly. Retention of the avian coronavirus infectious bronchitis virus envelope protein in the pre-Golgi compartments and physical interaction between the envelope and membrane proteins

  👤 Lim, K. P. 👤 Liu, D. X. ⏰ 2001 📚 Journal of Biological Chemistry

• Identification of a novel cleavage activity of the first papain-like proteinase domain encoded by open reading frame 1a of the coronavirus Avian infectious bronchitis virus and characterization of the cleavage products

  👤 Lim, K. P. 👤 Ng, Lisa F.P. 👤 Liu, D. X. ⏰ 2000 📚 Journal of Virology

• Identification of residues in the receptor-binding domain (RBD) of the spike protein of human coronavirus NL63 that are critical for the RBD-ACE2 receptor interaction

  👤 Lin, Han Xin 👤 Feng, Yan 👤 Wong, Gillian 👤 Wang, Liping 👤 Li, Bei 👤 Zhao, Xuesen 👤 Li, Yan 👤 Smaill, Fiona 👤 Zhang, Chengsheng ⏰ 2008 📚 Journal of General Virology

• Porcine deltacoronavirus nsp15 antagonizes interferon-β production independently of its endoribonuclease activity

  👤 Liu, Xiaorong 👤 Fang, Puxian 👤 Fang, Liurong 👤 Hong, Yingying 👤 Zhu, Xinyu 👤 Wang, Dang 👤 Peng, Guiqing 👤 Xiao, Shaobo ⏰ 2019 📚 Molecular Immunology

• Membrane association and dimerization of a cysteine-rich, 16-kilodalton polypeptide released from the C-terminal region of the coronavirus infectious bronchitis virus 1a polyprotein

  👤 Ng, Lisa F.P. 👤 Liu, D. X. ⏰ 2002 📚 Journal of Virology

• A lysine-methionine exchange in a coronavirus surface protein transforms a retention motif into an endocytosis signal

  👤 Paul, André 👤 Trincone, Anna 👤 Siewert, Sandra 👤 Herrler, Georg 👤 Schwegmann-Weßels, Christel ⏰ 2014 📚 Biological Chemistry

• ADP-ribose-1″-monophosphatase: A conserved coronavirus enzyme that is dispensable for viral replication in tissue culture

  👤 Putics, Ákos 👤 Filipowicz, Witold 👤 Hall, Jonathan 👤 Gorbalenya, Alexander E. 👤 Ziebuhr, John ⏰ 2005 📚 Journal of Virology

• Amino acid residues critical for RNA-binding in the N-terminal domain of the nucleocapsid protein are essential determinants for the infectivity of coronavirus in cultured cells

  👤 Tan, Yong Wah 👤 Fang, Shouguo 👤 Fan, Hui 👤 Lescar, Julien 👤 Liu, D. X. ⏰ 2006 📚 Nucleic Acids Research

• The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension

  👤 Te Velthuis, Aartjan J.W. 👤 Van Den Worm, Sjoerd H.E. 👤 Snijder, Eric J. ⏰ 2012 📚 Nucleic Acids Research

• The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase

  👤 Wei, Ping 👤 Fan, Keqiang 👤 Chen, Hao 👤 Ma, Liang 👤 Huang, Changkang 👤 Tan, Lei 👤 Xi, Dong 👤 Li, Chunmei 👤 Liu, Ying 👤 Cao, Aoneng 👤 Lai, Luhua ⏰ 2006 📚 Biochemical and Biophysical Research Communications

• Exceptionally potent neutralization of middle east respiratory syndrome coronavirus by human monoclonal antibodies

  👤 Ying, Tianlei 👤 Du, Lanying 👤 Ju, Tina W. 👤 Prabakaran, Ponraj 👤 Lau, Candy C.Y. 👤 Lu, Lu 👤 Liu, Qi 👤 Wang, Lili 👤 Feng, Yang 👤 Wang, Yanping 👤 Zheng, Bo Jian 👤 Yuen, Kwok Yung 👤 Jiang, Shibo 👤 Dimitrov, Dimiter S. ⏰ 2014 📚 Journal of Virology

• Sequence Motifs Involved in the Regulation of Discontinuous Coronavirus Subgenomic RNA Synthesis

  👤 Zúñiga, Sonia 👤 Sola, Isabel 👤 Alonso, Sara 👤 Enjuanes, Luis ⏰ 2004 📚 Journal of Virology