📚 Journal of Medicinal Chemistry

Articles (14)

• X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases

  👤 Báez-Santos, Yahira M. 👤 Barraza, Scott J. 👤 Wilson, Michael W. 👤 Agius, Michael P. 👤 Mielech, Anna M. 👤 Davis, Nicole M. 👤 Baker, Susan C. 👤 Larsen, Scott D. 👤 Mesecar, Andrew D. ⏰ 2014 📚 Journal of Medicinal Chemistry

• Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome - Coronavirus papain-like protease

  👤 Ghosh, Arun K. 👤 Takayama, Jun 👤 Aubin, Yoann 👤 Ratia, Kiira 👤 Chaudhuri, Rima 👤 Baez, Yahira 👤 Sleeman, Katrina 👤 Coughlin, Melissa 👤 Nichols, Daniel B. 👤 Mulhearn, Debbie C. 👤 Prabhakar, Bellur S. 👤 Baker, Susan C. 👤 Johnson, Michael E. 👤 Mesecar, Andrew D. ⏰ 2009 📚 Journal of Medicinal Chemistry

• Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: Design, synthesis, protein-ligand X-ray structure and biological evaluation

  👤 Ghosh, Arun K. 👤 Takayama, Jun 👤 Rao, Kalapala Venkateswara 👤 Ratia, Kiira 👤 Chaudhuri, Rima 👤 Mulhearn, Debbie C. 👤 Lee, Hyun 👤 Nichols, Daniel B. 👤 Baliji, Surendranath 👤 Baker, Susan C. 👤 Johnson, Michael E. 👤 Mesecar, Andrew D. ⏰ 2010 📚 Journal of Medicinal Chemistry

• Antiviral activity of glycyrrhizic acid derivatives against SARS-coronavirus

  👤 Hoever, Gerold 👤 Baltina, Lidia 👤 Michaelis, Martin 👤 Kondratenko, Rimma 👤 Baltina, Lia 👤 Tolstikov, Genrich A. 👤 Doerr, Hans W. 👤 Cinatl Jr., Jindrich ⏰ 2005 📚 Journal of Medicinal Chemistry

• Discovery, synthesis, and structure-based optimization of a series of N -(tert -Butyl)-2-(N -arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease

  👤 Jacobs, Jon 👤 Grum-Tokars, Valerie 👤 Zhou, Ya 👤 Turlington, Mark 👤 Saldanha, S. Adrian 👤 Chase, Peter 👤 Eggler, Aimee 👤 Dawson, Eric S. 👤 Baez-Santos, Yahira M. 👤 Tomar, Sakshi 👤 Mielech, Anna M. 👤 Baker, Susan C. 👤 Lindsley, Craig W. 👤 Hodder, Peter 👤 Mesecar, Andrew 👤 Stauffer, Shaun R. ⏰ 2013 📚 Journal of Medicinal Chemistry

• A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods

  👤 Kaeppler, Ulrich 👤 Stiefl, Nikolaus 👤 Schiller, Markus 👤 Vicik, Radim 👤 Breuning, Alexander 👤 Schmitz, Werner 👤 Rupprecht, Daniel 👤 Schmuck, Carsten 👤 Baumann, Knut 👤 Ziebuhr, John 👤 Schirmeister, Tanja ⏰ 2005 📚 Journal of Medicinal Chemistry

• Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target

  👤 Lin, Shing Yen 👤 Liu, Chia Ling 👤 Chang, Yu Ming 👤 Zhao, Jincun 👤 Perlman, Stanley 👤 Hou, Ming Hon ⏰ 2014 📚 Journal of Medicinal Chemistry

• Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease

  👤 Lu, I. Lin 👤 Mahindroo, Neeraj 👤 Liang, Po Huang 👤 Peng, Yi Hui 👤 Kuo, Chih Jung 👤 Tsai, Keng Chang 👤 Hsieh, Hsing Pang 👤 Chao, Yu Sheng 👤 Wu, Su Ying ⏰ 2006 📚 Journal of Medicinal Chemistry

• An overview of severe acute respiratory syndrome-coronavirus (SARS-CoV) 3CL protease inhibitors: Peptidomimetics and small molecule chemotherapy

  👤 Pillaiyar, Thanigaimalai 👤 Manickam, Manoj 👤 Namasivayam, Vigneshwaran 👤 Hayashi, Yoshio 👤 Jung, Sang Hun ⏰ 2016 📚 Journal of Medicinal Chemistry

• Discovery of Hydrocarbon-Stapled Short α-Helical Peptides as Promising Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Fusion Inhibitors

  👤 Wang, Chao 👤 Xia, Shuai 👤 Zhang, Peiyu 👤 Zhang, Tianhong 👤 Wang, Weicong 👤 Tian, Yangli 👤 Meng, Guangpeng 👤 Jiang, Shibo 👤 Liu, Keliang ⏰ 2018 📚 Journal of Medicinal Chemistry

• Design, synthesis, testing, and quantitative structure-activity relationship analysis of substituted salicylaldehyde Schiff bases of 1-amino-3-hydroxyguanidine tosylate as new antiviral agents against coronavirus

  👤 Wang, Pou Hsiung 👤 Lien, Eric J. 👤 Keck, James G. 👤 Lai, Michael M.C. ⏰ 1990 📚 Journal of Medicinal Chemistry

• Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus

  👤 Wen, Chih Chun 👤 Kuo, Yueh Hsiung 👤 Jan, Jia Tsrong 👤 Liang, Po Huang 👤 Wang, Sheng Yang 👤 Liu, Hong Gi 👤 Lee, Ching Kuo 👤 Chang, Shang Tzen 👤 Kuo, Chih Jung 👤 Lee, Shoei Sheng 👤 Hou, Chia Chung 👤 Hsiao, Pei Wen 👤 Chien, Shih Chang 👤 Shyur, Lie Fen 👤 Yang, Ning Sun ⏰ 2007 📚 Journal of Medicinal Chemistry

• Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor

  👤 Yang, Syaulan 👤 Chen, Shu Jen 👤 Hsu, Min Feng 👤 Wu, Jen Dar 👤 Tseng, Chien Te K. 👤 Liu, Yu Fan 👤 Chen, Hua Chien 👤 Kuo, Chun Wei 👤 Wu, Chi Shen 👤 Chang, Li Wen 👤 Chen, Wen Chang 👤 Liao, Shao Ying 👤 Chang, Teng Yuan 👤 Hung, Hsin Hui 👤 Shr, Hui Lin 👤 Liu, Cheng Yuan 👤 Huang, Yu An 👤 Chang, Ling Yin 👤 Hsu, Jen Chi 👤 Peters, Clarence J. 👤 Wang, Andrew H.J. 👤 Hsu, Ming Chu ⏰ 2006 📚 Journal of Medicinal Chemistry

• Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors

  👤 Zhou, Lu 👤 Liu, Ying 👤 Zhang, Weilin 👤 Wei, Ping 👤 Huang, Changkang 👤 Pei, Jianfeng 👤 Yuan, Yaxia 👤 Lai, Luhua ⏰ 2006 📚 Journal of Medicinal Chemistry