👤 Takayama, Jun

Keywords

🔗 enzymatic activity (29) 🔗 severe acute (1373) 🔗 papain-like protease (67) 🔗 innate immune (105) 🔗 human coronavirus (623) 🔗 immune response (314) 🔗 respiratory syndrome (2004) 🔗 acute respiratory (1734) 🔗 results indicate (178) 🔗 viral replication (258) 🔗 drug design (36) 🔗 crystal structure (114)

Articles (3)

Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases
👤 Clementz, Mark A. 👤 Chen, Zhongbin 👤 Banach, Bridget S. 👤 Wang, Yanhua 👤 Sun, Li 👤 Ratia, Kiira 👤 Baez-Santos, Yahira M. 👤 Wang, Jie 👤 Takayama, Jun 👤 Ghosh, Arun K. 👤 Li, Kui 👤 Mesecar, Andrew D. 👤 Baker, Susan C. ⏰ 2010 📚 Journal of Virology
Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome - Coronavirus papain-like protease
👤 Ghosh, Arun K. 👤 Takayama, Jun 👤 Aubin, Yoann 👤 Ratia, Kiira 👤 Chaudhuri, Rima 👤 Baez, Yahira 👤 Sleeman, Katrina 👤 Coughlin, Melissa 👤 Nichols, Daniel B. 👤 Mulhearn, Debbie C. 👤 Prabhakar, Bellur S. 👤 Baker, Susan C. 👤 Johnson, Michael E. 👤 Mesecar, Andrew D. ⏰ 2009 📚 Journal of Medicinal Chemistry
Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: Design, synthesis, protein-ligand X-ray structure and biological evaluation
👤 Ghosh, Arun K. 👤 Takayama, Jun 👤 Rao, Kalapala Venkateswara 👤 Ratia, Kiira 👤 Chaudhuri, Rima 👤 Mulhearn, Debbie C. 👤 Lee, Hyun 👤 Nichols, Daniel B. 👤 Baliji, Surendranath 👤 Baker, Susan C. 👤 Johnson, Michael E. 👤 Mesecar, Andrew D. ⏰ 2010 📚 Journal of Medicinal Chemistry