🔗 Fusion proteins

Articles (43)

• Influence of hydrophobic and electrostatic residues on SARS-coronavirus S2 protein stability: Insights into mechanisms of general viral fusion and inhibitor design

  👤 Aydin, Halil 👤 Al-Khooly, Dina 👤 Lee, Jeffrey E. ⏰ 2014 📚 Protein Science

• Conformational reorganization of the SARS coronavirus spike following receptor binding: Implications for membrane fusion

  👤 Beniac, Daniel R. 👤 de Varennes, Shauna L. 👤 Andonov, Anton 👤 He, Runtao 👤 Booth, Tim F. ⏰ 2007 📚 PLoS ONE

• Ginkgolic acid inhibits fusion of enveloped viruses.

  👤 Borenstein, Ronen 👤 Hanson, Barbara A 👤 Markosyan, Ruben M 👤 Gallo, Elisa S 👤 Narasipura, Srinivas D 👤 Bhutta, Maimoona 👤 Shechter, Oren 👤 Lurain, Nell S 👤 Cohen, Fredric S 👤 Al-Harthi, Lena 👤 Nicholson, Daniel A ⏰ 2020 📚 Sci Rep

• Cathepsin L functionally cleaves the severe acute respiratory syndrome coronavirus class I fusion protein upstream of rather than adjacent to the fusion peptide

  👤 Bosch, Berend Jan 👤 Bartelink, Willem 👤 Rottier, Peter J.M. ⏰ 2008 📚 Journal of Virology

• Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides

  👤 Bosch, Berend Jan 👤 Martina, Byron E.E. 👤 Van Der Zee, Ruurd 👤 Lepault, Jean 👤 Haijema, Bert Jan 👤 Versluis, Cees 👤 Heck, Albert J.R. 👤 De Groot, Raoul 👤 Osterhaus, Albert D.M.E. 👤 Rottier, Peter J.M. ⏰ 2004 📚 Proceedings of the National Academy of Sciences of the United States of America

• Coronavirus escape from Heptad Repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein

  👤 Bosch, Berend Jan 👤 Rossen, John W.A. 👤 Bartelink, Willem 👤 Zuurveen, Stephanie J. 👤 De Haan, Cornelis A.M. 👤 Duquerroy, Stephane 👤 Boucher, Charles A.B. 👤 Rottier, Peter J.M. ⏰ 2008 📚 Journal of Virology

• The coronavirus spike protein is a class I virus fusion protein: Structural and functional characterization of the fusion core complex

  👤 Bosch, Berend Jan 👤 Van der Zee, Ruurd 👤 De Haan, Cornelis A.M. 👤 Rottier, Peter J.M. ⏰ 2003 📚 Journal of Virology

• Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner

  👤 Burkard, Christine 👤 Verheije, Monique H. 👤 Wicht, Oliver 👤 van Kasteren, Sander I. 👤 van Kuppeveld, Frank J. 👤 Haagmans, Bart L. 👤 Pelkmans, Lucas 👤 Rottier, Peter J.M. 👤 Bosch, Berend Jan 👤 de Haan, Cornelis A.M. ⏰ 2014 📚 PLoS Pathogens

• Cleavage of group 1 coronavirus spike proteins: How furin cleavage is traded off against heparan sulfate binding upon cell culture adaptation

  👤 De Haan, C. A.M. 👤 Haijema, B. J. 👤 Schellen, P. 👤 Wichgers Schreur, P. 👤 Te Lintelo, E. 👤 Vennema, H. 👤 Rottier, P. J.M. ⏰ 2008 📚 Journal of Virology

• Coronavirus and influenza virus proteolytic priming takes place in tetraspanin-enriched membrane microdomains

  👤 Earnest, James T. 👤 Hantak, Michael P. 👤 Park, Jung Eun 👤 Gallagher, Tom ⏰ 2015 📚 Journal of Virology

• Serine-scanning mutagenesis studies of the C-terminal heptad repeats in the SARS coronavirus S glycoprotein highlight the important role of the short helical region

  👤 Follis, Kathryn E. 👤 York, Joanne 👤 Nunberg, Jack H. ⏰ 2005 📚 Virology

• Interaction of a peptide from the pre-transmembrane domain of the severe acute respiratory syndrome coronavirus spike protein with phospholipid membranes

  👤 Guillen, Jaime 👤 Moreno, Miguel R. 👤 Pérez-Berná, Ana J. 👤 Bernabeu, Angela 👤 Villalaín, José ⏰ 2007 📚 Journal of Physical Chemistry B

• Solution structure of the severe acute respiratory syndrome-coronavirus heptad repeat 2 domain in the prefusion state

  👤 Hakansson-McReynolds, Susanna 👤 Jiang, Shaokai 👤 Rong, Lijun 👤 Caffrey, Michael ⏰ 2006 📚 Journal of Biological Chemistry

• Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity

  👤 Harcourt, Brian H. 👤 Jukneliene, Dalia 👤 Kanjanahaluethai, Amornrat 👤 Bechill, John 👤 Severson, Kari M. 👤 Smith, Catherine M. 👤 Rota, Paul A. 👤 Baker, Susan C. ⏰ 2004 📚 Journal of Virology

• Ready, set, fuse! the coronavirus spike protein and acquisition of fusion competence

  👤 Heald-Sargent, Taylor 👤 Gallagher, Tom ⏰ 2012 📚 Viruses

• Identification of in vivo-interacting domains of the murine coronavirus nucleocapsid protein

  👤 Hurst, Kelley R. 👤 Koetzner, Cheri A. 👤 Masters, Paul S. ⏰ 2009 📚 Journal of Virology

• Structural characterization of the fusion-active complex of severe acute respiratory syndrome (SARS) coronavirus

  👤 Ingallinella, Paolo 👤 Bianchi, Elisabetta 👤 Finotto, Marco 👤 Cantoni, Giovanna 👤 Eckert, Debra M. 👤 Supekar, Vinit M. 👤 Bruckmann, Chiara 👤 Carfi, Andrea 👤 Pessi, Antonello ⏰ 2004 📚 Proceedings of the National Academy of Sciences of the United States of America

• A fluorogenic peptide cleavage assay to screen for proteolytic activity: Applications for coronavirus spike protein activation

  👤 Jaimes, Javier A. 👤 Millet, Jean K. 👤 Goldstein, Monty E. 👤 Whittaker, Gary R. 👤 Straus, Marco R. ⏰ 2019 📚 Journal of Visualized Experiments

• Biochemical Analysis of Coronavirus Spike Glycoprotein Conformational Intermediates during Membrane Fusion

  👤 Kawase, Miyuki 👤 Kataoka, Michiyo 👤 Shirato, Kazuya 👤 Matsuyama, Shutoku ⏰ 2019 📚 Journal of virology

• Amino acids 1055 to 1192 in the S2 region of severe acute respiratory syndrome coronavirus S protein induce neutralizing antibodies: Implications for the development of vaccines and antiviral agents

  👤 Keng, Choong Tat 👤 Zhang, Aihua 👤 Shen, Shuo 👤 Lip, Kuo Ming 👤 Fielding, Burtram C. 👤 Tan, Timothy H.P. 👤 Chou, Chih Fong 👤 Chay, Boon Loh 👤 Wang, Sifang 👤 Fu, Jianlin 👤 Yang, Xiaoming 👤 Seng, Gee Lim 👤 Hong, Wanjin 👤 Tan, Yee Joo ⏰ 2005 📚 Journal of Virology

• The nonstructural protein 8 (nsp8) of the SARS coronavirus interacts with its ORF6 accessory protein

  👤 Kumar, Purnima 👤 Gunalan, Vithiagaran 👤 Liu, Boping 👤 Chow, Vincent T.K. 👤 Druce, Julian 👤 Birch, Chris 👤 Catton, Mike 👤 Fielding, Burtram C. 👤 Tan, Yee Joo 👤 Lal, Sunil K. ⏰ 2007 📚 Virology

• Mucosal immunization with surface-displayed severe acute respiratory syndrome coronavirus spike protein on Lactobacillus casei induces neutralizing antibodies in mice

  👤 Lee, Jong Soo 👤 Poo, Haryoung 👤 Han, Dong P. 👤 Hong, Seung Pyo 👤 Kim, Kwang 👤 Cho, Michael W. 👤 Kim, Eun 👤 Sung, Moon Hee 👤 Kim, Chul Joong ⏰ 2006 📚 Journal of Virology

• A polycistronic mRNA specified by the coronavirus infectious bronchitis virus

  👤 Liu, D. X. 👤 Cavanagh, D. 👤 Green, P. 👤 Inglis, S. C. ⏰ 1991 📚 Virology

• Identification of two new polypeptides encoded by mRNA5 of the coronavirus infectious bronchitis virus

  👤 Liu, D. X. 👤 Inglis, S. C. ⏰ 1992 📚 Virology

• Roles in cell-to-cell fusion of two conserved hydrophobic regions in the murine coronavirus spike protein

  👤 Luo, Zongli 👤 Weiss, Susan R. ⏰ 1998 📚 Virology

• Characterization of a highly conserved domain within the severe acute respiratory syndrome coronavirus spike protein S2 domain with characteristics of a viral fusion peptide

  👤 Madu, Ikenna G. 👤 Roth, Shoshannah L. 👤 Belouzard, Sandrine 👤 Whittaker, Gary R. ⏰ 2009 📚 Journal of Virology

• Production of pseudotyped particles to study highly pathogenic coronaviruses in a biosafety level 2 setting

  👤 Millet, Jean K. 👤 Tang, Tiffany 👤 Nathan, Lakshmi 👤 Jaimes, Javier A. 👤 Hsu, Hung Lun 👤 Daniel, Susan 👤 Whittaker, Gary R. ⏰ 2019 📚 Journal of Visualized Experiments

• Peptides derived from HIV-1, HIV-2, Ebola virus, SARS coronavirus and coronavirus 229E exhibit high affinity binding to the formyl peptide receptor

  👤 Mills, John S. ⏰ 2006 📚 Biochimica et Biophysica Acta - Molecular Basis of Disease

• Identification of the fusion peptide-containing region in betacoronavirus spike glycoproteins

  👤 Ou, Xiuyuan 👤 Zheng, Wangliang 👤 Shan, Yiwei 👤 Mu, Zhixia 👤 Dominguez, Samuel R. 👤 Holmes, Kathryn V. 👤 Qian, Zhaohui ⏰ 2016 📚 Journal of Virology

• A three-stemmed mRNA pseudoknot in the SARS coronavirus frameshift signal

  👤 Plant, Ewan P. 👤 Pérez-Alvarado, Gabriela C. 👤 Jacobs, Jonathan L. 👤 Mukhopadhyay, Bani 👤 Hennig, Mirko 👤 Dinman, Jonathan D. ⏰ 2005 📚 PLoS Biology

• Identification and characterization of the putative fusion peptide of the severe acute respiratory syndrome-associated coronavirus spike protein

  👤 Sainz Jr., Bruno 👤 Rausch, Joshua M. 👤 Gallaher, William R. 👤 Garry, Robert F. 👤 Wimley, William C. ⏰ 2005 📚 Journal of Virology

• Role of spike protein endodomains in regulating coronavirus entry

  👤 Shulla, Ana 👤 Gallagher, Tom ⏰ 2009 📚 Journal of Biological Chemistry

• Structural characterization of the SARS-coronavirus spike S fusion protein core

  👤 Tripet, Brian 👤 Howard, Megan W. 👤 Jobling, Michael 👤 Holmes, Randall K. 👤 Holmes, Kathryn V. 👤 Hodges, Robert S. ⏰ 2004 📚 Journal of Biological Chemistry

• Self-assembly of severe acute respiratory syndrome coronavirus membrane protein

  👤 Tseng, Ying Tzu 👤 Wang, Shiu Mei 👤 Huang, Kuo Jung 👤 I-Ru Lee, Amber 👤 Chiang, Chien Cheng 👤 Wang, Chin Tien ⏰ 2010 📚 Journal of Biological Chemistry

• Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

  👤 Walls, Alexandra C. 👤 Tortorici, M. Alejandra 👤 Bosch, Berend Jan 👤 Frenz, Brandon 👤 Rottier, Peter J.M. 👤 DiMaio, Frank 👤 Rey, Félix A. 👤 Veesler, David ⏰ 2016 📚 Nature

• Discovery of Hydrocarbon-Stapled Short α-Helical Peptides as Promising Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Fusion Inhibitors

  👤 Wang, Chao 👤 Xia, Shuai 👤 Zhang, Peiyu 👤 Zhang, Tianhong 👤 Wang, Weicong 👤 Tian, Yangli 👤 Meng, Guangpeng 👤 Jiang, Shibo 👤 Liu, Keliang ⏰ 2018 📚 Journal of Medicinal Chemistry

• The nucleocapsid protein of coronavirus mouse hepatitis virus interacts with the cellular heterogeneous nuclear ribonucleoprotein A1 in vitro and in vivo

  👤 Wang, Yicheng 👤 Zhang, Xuming ⏰ 1999 📚 Virology

• Identification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell

  👤 Wicht, Oliver 👤 Burkard, Christine 👤 de Haan, Cornelis A.M. 👤 van Kuppeveld, Frank J.M. 👤 Rottier, Peter J.M. 👤 Bosch, Berend Jan ⏰ 2014 📚 Journal of Virology

• Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core

  👤 Xu, Yanhui 👤 Lou, Zhiyong 👤 Liu, Yiwei 👤 Pang, Hai 👤 Tien, Po 👤 Gao, George F. 👤 Rao, Zihe ⏰ 2004 📚 Journal of Biological Chemistry

• Crystallization and preliminary crystallographic analysis of the heptad-repeat complex of SARS coronavirus spike protein

  👤 Xu, Yanhui 👤 Su, Nan 👤 Qin, Lan 👤 Bai, Zhihong 👤 Gao, George F. 👤 Rao, Zihe ⏰ 2004 📚 Acta Crystallographica Section D: Biological Crystallography

• Characterization of the heptad repeat regions, HR1 and HR2, and design of a fusion core structure model of the spike protein from Severe Acute Respiratory Syndrome (SARS) coronavirus

  👤 Xu, Yanhui 👤 Zhu, Jieqing 👤 Liu, Yiwei 👤 Lou, Zhiyong 👤 Yuan, Fang 👤 Liu, Yueyong 👤 Cole, David K. 👤 Ni, Ling 👤 Su, Nan 👤 Qin, Lan 👤 Li, Xu 👤 Bai, Zhihong 👤 Bell, John I. 👤 Pang, Hai 👤 Tien, Po 👤 Gao, George F. 👤 Rao, Zihe ⏰ 2004 📚 Biochemistry

• Genetic analysis of determinants for spike glycoprotein assembly into murine coronavirus virions: Distinct roles for charge-rich and cysteine-rich regions of the endodomain

  👤 Ye, Rong 👤 Montalto-Morrison, Cynthia 👤 Masters, Paul S. ⏰ 2004 📚 Journal of Virology

• The 3C-like proteinase of an invertebrate nidovirus links coronavirus and potyvirus homologs

  👤 Ziebuhr, John 👤 Bayer, Sonja 👤 Cowley, Jeff A. 👤 Gorbalenya, Alexander E. ⏰ 2003 📚 Journal of Virology