🔗 Six-helix bundle

Articles (19)

• Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides

  👤 Bosch, Berend Jan 👤 Martina, Byron E.E. 👤 Van Der Zee, Ruurd 👤 Lepault, Jean 👤 Haijema, Bert Jan 👤 Versluis, Cees 👤 Heck, Albert J.R. 👤 De Groot, Raoul 👤 Osterhaus, Albert D.M.E. 👤 Rottier, Peter J.M. ⏰ 2004 📚 Proceedings of the National Academy of Sciences of the United States of America

• Protective effect of intranasal regimens containing peptidic middle east respiratory syndrome coronavirus fusion inhibitor against MERS-CoV infection

  👤 Channappanavar, Rudragouda 👤 Lu, Lu 👤 Xia, Shuai 👤 Du, Lanying 👤 Meyerholz, David K. 👤 Perlman, Stanley 👤 Jiang, Shibo ⏰ 2015 📚 Journal of Infectious Diseases

• Fusion core structure of the severe acute respiratory syndrome coronavirus (SARS-CoV): In search of potent SARS-CoV entry inhibitors

  👤 Chu, Ling Hon Matthew 👤 Chan, Siu Hong 👤 Tsai, Sau Na 👤 Wang, Yi 👤 Cheng, Christopher Hon Ki 👤 Wong, Kam Bo 👤 Waye, Mary Miu Yee 👤 Ngai, Sai Ming ⏰ 2008 📚 Journal of Cellular Biochemistry

• Serine-scanning mutagenesis studies of the C-terminal heptad repeats in the SARS coronavirus S glycoprotein highlight the important role of the short helical region

  👤 Follis, Kathryn E. 👤 York, Joanne 👤 Nunberg, Jack H. ⏰ 2005 📚 Virology

• The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses

  👤 Forni, Diego 👤 Filippi, Giulia 👤 Cagliani, Rachele 👤 De Gioia, Luca 👤 Pozzoli, Uberto 👤 Al-Daghri, Nasser 👤 Clerici, Mario 👤 Sironi, Manuela ⏰ 2015 📚 Scientific Reports

• Structural characterization of the fusion-active complex of severe acute respiratory syndrome (SARS) coronavirus

  👤 Ingallinella, Paolo 👤 Bianchi, Elisabetta 👤 Finotto, Marco 👤 Cantoni, Giovanna 👤 Eckert, Debra M. 👤 Supekar, Vinit M. 👤 Bruckmann, Chiara 👤 Carfi, Andrea 👤 Pessi, Antonello ⏰ 2004 📚 Proceedings of the National Academy of Sciences of the United States of America

• Biochemical Analysis of Coronavirus Spike Glycoprotein Conformational Intermediates during Membrane Fusion

  👤 Kawase, Miyuki 👤 Kataoka, Michiyo 👤 Shirato, Kazuya 👤 Matsuyama, Shutoku ⏰ 2019 📚 Journal of virology

• Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: Implications for virus fusogenic mechanism and identification of fusion inhibitors

  👤 Liu, Shuwen 👤 Xiao, Gengfu 👤 Chen, Yibang 👤 He, Yuxian 👤 Niu, Jinkui 👤 Escalante, Carlos R. 👤 Xiong, Huabao 👤 Farmar, James 👤 Debnath, Asim K. 👤 Tien, Po 👤 Jiang, Shibo ⏰ 2004 📚 Lancet

• Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

  👤 Lu, Lu 👤 Liu, Qi 👤 Zhu, Yun 👤 Chan, Kwok Hung 👤 Qin, Lili 👤 Li, Yuan 👤 Wang, Qian 👤 Chan, Jasper Fuk Woo 👤 Du, Lanying 👤 Yu, Fei 👤 Ma, Cuiqing 👤 Ye, Sheng 👤 Yuen, Kwok Yung 👤 Zhang, Rongguang 👤 Jiang, Shibo ⏰ 2014 📚 Nature Communications

• Two-step conformational changes in a coronavirus envelope glycoprotein mediated by receptor binding and proteolysis

  👤 Matsuyama, Shutoku 👤 Taguchi, Fumihiro ⏰ 2009 📚 Journal of Virology

• Characterization of the prefusion and transition states of severe acute respiratory syndrome coronavirus S2-HR2

  👤 McReynolds, Susanna 👤 Jiang, Shaokai 👤 Guo, Ying 👤 Celigoy, Jessica 👤 Schar, Christine 👤 Rong, Lijun 👤 Caffrey, Michael ⏰ 2008 📚 Biochemistry

• Role of spike protein endodomains in regulating coronavirus entry

  👤 Shulla, Ana 👤 Gallagher, Tom ⏰ 2009 📚 Journal of Biological Chemistry

• Identification of a novel inhibitor against middle east respiratory syndrome coronavirus

  👤 Sun, Yaping 👤 Zhang, Huaidong 👤 Shi, Jian 👤 Zhang, Zhe 👤 Gong, Rui ⏰ 2017 📚 Viruses

• Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus

  👤 Tripet, Brian 👤 Kao, Daniel J. 👤 Jeffers, Scott A. 👤 Holmes, Kathryn V. 👤 Hodges, Robert S. ⏰ 2006 📚 Journal of Structural Biology

• Potent MERS-CoV fusion inhibitory peptides identified from HR2 domain in spike protein of bat coronavirus HKU4

  👤 Xia, Shuai 👤 Lan, Qiaoshuai 👤 Pu, Jing 👤 Wang, Cong 👤 Liu, Zezhong 👤 Xu, Wei 👤 Wang, Qian 👤 Liu, Huan 👤 Jiang, Shibo 👤 Lu, Lu ⏰ 2019 📚 Viruses

• A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

  👤 Xia, Shuai 👤 Yan, Lei 👤 Xu, Wei 👤 Agrawal, Anurodh Shankar 👤 Algaissi, Abdullah 👤 Tseng, Chien Te K. 👤 Wang, Qian 👤 Du, Lanying 👤 Tan, Wenjie 👤 Wilson, Ian A. 👤 Jiang, Shibo 👤 Yang, Bei 👤 Lu, Lu ⏰ 2019 📚 Science Advances

• Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core

  👤 Xu, Yanhui 👤 Lou, Zhiyong 👤 Liu, Yiwei 👤 Pang, Hai 👤 Tien, Po 👤 Gao, George F. 👤 Rao, Zihe ⏰ 2004 📚 Journal of Biological Chemistry

• Crystallization and preliminary crystallographic analysis of the heptad-repeat complex of SARS coronavirus spike protein

  👤 Xu, Yanhui 👤 Su, Nan 👤 Qin, Lan 👤 Bai, Zhihong 👤 Gao, George F. 👤 Rao, Zihe ⏰ 2004 📚 Acta Crystallographica Section D: Biological Crystallography

• Biophysical characterization of HRC peptide analogs interaction with heptad repeat regions of the SARS-coronavirus Spike fusion protein core

  👤 Yan, Zhe 👤 Tripet, Brian 👤 Hodges, Robert S. ⏰ 2006 📚 Journal of Structural Biology