๐ Evaluation of homology modeling of the severe acute respiratory syndrome (SARS) coronavirus main protease for structure based drug design
To accelerate the development of drugs against severe acute respiratory syndrome (SARS), we constructed a homology model of the SARS coronavirus main protease using our modeling software, FAMS Ligand&Complex, and released it before the X-ray structure was solved. The X-ray structure showed our model as accurately predicted and useful for structure based drug design. ยฉ 2004 Pharmaceutical Society of Japan.
keywords
๐ severe acute (1373)
๐ main protease (44)
๐ drug design (36)
๐ respiratory syndrome (2004)
๐ acute respiratory (1734)
author
๐ค Takeda-Shitaka, Mayuko
๐ค Nojima, Hiroyuki
๐ค Takaya, Daisuke
๐ค Kanou, Kazuhiko
๐ค Iwadate, Mitsuo
๐ค Umeyama, Hideaki
year
โฐ 2004
issn
๐ 00092363 13475223
volume
52
number
5
page
643-645
citedbycount
12
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