👤 Lei, Jian

Keywords

🔗 syndrome coronavirus (1074) 🔗 papain-like protease (67) 🔗 host cell (262) 🔗 innate immune (105) 🔗 immune response (314) 🔗 respiratory syndrome (2004) 🔗 crystal structure (114) 🔗 magnetic resonance (14) 🔗 severe acute (1373) 🔗 renal failure (30) 🔗 innate immunity (35) 🔗 human coronavirus (623) 🔗 acute respiratory (1734) 🔗 viral replication (258)

Articles (4)

Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin
👤 Lei, Jian 👤 Hilgenfeld, Rolf ⏰ 2016 📚 Virologica Sinica
Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein
👤 Lei, Jian 👤 Kusov, Yuri 👤 Hilgenfeld, Rolf ⏰ 2018 📚 Antiviral Research
Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features
👤 Lei, Jian 👤 Mesters, Jeroen R. 👤 Drosten, Christian 👤 Anemüller, Stefan 👤 Ma, Qingjun 👤 Hilgenfeld, Rolf ⏰ 2014 📚 Antiviral Research
P53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1
👤 Ma-Lauer, Yue 👤 Carbajo-Lozoya, Javier 👤 Hein, Marco Y. 👤 Müller, Marcel A. 👤 Deng, Wen 👤 Lei, Jian 👤 Meyer, Benjamin 👤 Kusov, Yuri 👤 Von Brunn, Brigitte 👤 Bairad, Dev Raj 👤 Hünten, Sabine 👤 Drosten, Christian 👤 Hermeking, Heiko 👤 Leonhardt, Heinrich 👤 Mann, Matthias 👤 Hilgenfeld, Rolf 👤 Von Brunn, Albrecht ⏰ 2016 📚 Proceedings of the National Academy of Sciences of the United States of America